Medical Doctor Cancer Center
Resume:
Linda Hamadene
Medical Doctor
Dedicated Medical Doctor with over five years of experience in cancer immunology research at Memorial Sloan Kettering Cancer Center and then at Weill Cornell Medicine. Google Scholar Citations *****.*********@*****.*** 516-***-****
Virginia, USA linkedin.com/in/linda-hamadene-md-6a3243190 DEGREES/CERTIFICATES
Educational Commission for Foreign Medical Graduates Certification (05/2019) ECFMG is the authorized credential evaluation and guidance agency for non-U.S. physicians and graduates of non-U.S. medical schools Medical Doctor Degree (09/2015)
Seven years of medical school (pre-clinical, clinical, and an intern year) PUBLICATIONS
original research paper
T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants Author(s)
Daniel Hirschhorn, Sadna Budhu, Lukas Kraehenbuehl, Mathieu Gigoux, David Schröder, Andrew Chow, Jacob M Ricca, Billel Gasmi, Olivier De Henau, Levi Mark B Mangarin, Yanyun Li, Linda Hamadene, Anne-Laure Flamar, Hyejin Choi, Czrina A Cortez, Cailian Liu, Aliya Holland, Sara Schad, Isabell Schulze, Allison Betof Warner, Travis J Hollmann, Arshi Arora, Katherine S Panageas, Gabrielle A Rizzuto, Rebekka Duhen, Andrew D Weinberg, Christine N Spencer, David Ng, Xue-Yan He, Jean Albrengues, David Redmond, Mikala Egeblad, Jedd D Wolchok, Taha Merghoub.
03/30/2023
Cell
article link
original research paper
Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness
Author(s)
Daniel Hirschhorn, Allison Betof Warner, Rachana Maniyar, Andrew Chow, Levi M.B. Mangarin, Adam D. Cohen, Linda Hamadene, Gabrielle A. Rizzuto, Sadna Budhu, Nathan Suek, Cailian Liu, Alan N. Houghton, Taha Merghoub, and Jedd D. Wolchok. 10/22/2021
JCI Insight
article link
poster presentation
Immune modulation of the T cell repertoire in mice following immunotherapy and chemotherapy combination treatments
Author(s)
Yuval Elhanati; Mariam M. George; Hyejin Choi; Rachana Maniyar; Linda Hamadane; Neeman Mohibullah; Benjamin D. Greenbaum; Taha Merghoub.
04/04/2023
It was presented at the American Association for Cancer Research (AACR) poster link poster presentation
T cell immunotherapies trigger neutrophils to eliminate heterogenous tumors Author(s)
Sadna Budhu, David Redmond, Jacob Ricca, Billel Gasmi, Mathieu Gigoux, Cailian Liu, Yanyun Li, Czrina Cortez, David Schroder, Arshi Arora, Travis Hollman, Lukas Kraehenbuehl, Hyejin Choi, Sara Schad, Isabell Schulze, Rebekka Duhen, Andrew Weinberg, Andrew Chow, Mikala Egeblad, Katherine Panageas, Gabrielle Rizzuto, Olivier de Henau, Aliya Holland, Jean Albrengues, Linda Hamadane, David Ng, Xue-Yan He, Jedd Wolchok, Taha Merghoub and Daniel Hirschhorn. 11/07/2022
It was presented at the Society for Immunotherapy of Cancer (SITC) poster link April 10, 2025 Page 2 of 6
PUBLICATIONS
poster presentation
Signal-regulatory protein alpha (SIRPα) confers tumor cell resistance to anti-tumor immunity," which was presented at SITC 2022 (Society for Immunotherapy of Cancer
Author(s)
Chien-Huan Weng, Linda Hamadene, Shabnam Eghbali, Divya Venkatesh, Sébastien Monette, Levi Mangarin, Fadi Samaan, Cailian Liu, Pamela Holland, Jedd Wolchok and Taha Merghoub.
11/07/2022
It was presented at the Society for Immunotherapy of Cancer (SITC) poster link poster presentation
combination of cyclophosphamide with immune checkpoint blockade inhibition elicits potent tumor control in a preclinical melanoma model
Author(s)
Linda Hamadene; Mariam M. George; Daniel Hirschhorn; Alan N. Houghton; Allison Betof Warner; Jedd D. Wolchok; Taha Merghoub. May 2022
I presented this poster abstract at the Geoffrey Beene Cancer Retreat/Memorial Sloan Kettering Cancer Center. poster presentation
Potential role of CD47 in T cell exhaustion program Author(s)
Chien-Huan Weng; Fadi Samaan; Sadna Budhu; Levi Mangarin; Sébastien Monette; Cailian Liu; Stephane Pourpe; Linda Hamadene; Hong Zhong; Xia Yang; David Schroder; Roberta Zappasodi; Pamela Holland; Jedd D. Wolchok; Taha Merghoub. 06/15/2022
It was presented at the American Association for Cancer Research (AACR) poster link poster presentation
Combination of cyclophosphamide with immune checkpoint blockade inhibition elicits potent tumor control in a preclinical melanoma model
Author(s)
Mariam M. George; Allison Betof Warner; Linda Hamadene; Daniel Hirschhorn; Alan N. Houghton; Jedd D. Wolchok; Taha Merghoub. 06/15/2022
It was presented at the American Association for Cancer Research (AACR) poster link poster presentation
Combination of cyclophosphamide chemotherapy with immune modulation overcomes resistance to checkpoint blockade in a pre-clinical melanoma model
Author(s)
Allison Betof Warner; Daniel Hirschhorn; Levi M. Mangarin; Linda Hamadene; Adam D. Cohen; Gabrielle A. Rizzuto; Jedd D. Wolchok; Taha Merghoub.
07/01/2021
It was presented at the American Association for Cancer Research (AACR) poster link April 10, 2025 Page 3 of 6
WORK EXPERIENCE
Research Specialist
Weill Cornell Medicine
12/2022 - 11/2024, NY, USA
Merghoub Laboratory, part of the Edward Meyer Cancer Center, led by Dr. Jedd D. Wolchok. Our research project is focusing on the study of means to improve response to immune-based therapies in cancer. We are studying the effects of combining chemotherapy with immunotherapy and its role in regulating the anti-tumor activity in the context of multiple currently approved treatment regimens.
Design and develop preclinical research models focused on improving cancer patients' responses to FDA-approved immune-based therapies. Collect, analyze, and interpret data, then present them during our Laboratory meetings. Establish a biorepository bank permitting the collection and processing of human tumor samples helpful for multiple clinical trials. Patient Medical Chart Review for a Retrospective Study Prostate-Sparing Cystectomies for Bladder Cancer. Patient enrollment for a Multi-Cancer Early Detection Test clinical trial focused on cancer screening. Read and interpret scientific and medical literature and evaluate the study design and results. Good Clinical Practice (GCP) and Human Subjects Protection (HSP) certification. Contact : Pr. Taha Merghoub - *********@***.*******.*** Research Assistant
Memorial Sloan Kettering Cancer Center
04/2022 - 11/2022, NY, USA
Merghoub-Wolchok Laboratory
I have been promoted to a Research Assistant position as I am working on different projects mainly focusing on improving anti tumor immunity.
Contact : Pr. Taha Merghoub - *********@***.*******.*** Senior Research Technician
Memorial Sloan Kettering Cancer Center
11/2019 - 04/2022, NY, USA
Merghoub-Wolchok Laboratory
Our research project is focusing on the study of means to improve response to immune-based therapies in cancer. We are studying the effects of combining chemotherapy with immunotherapy and its role in regulating the anti-tumor activity in the context of multiple currently approved treatment regimens.
Read and interpret scientific and medical literature. designing and conducting In vivo and in vitro experiments. banking blood/tumor tissue under different protocols for further use in basic research science. Contact : Pr. Taha Merghoub - *********@***.*******.*** Intern
Beni Messous Hospital
12/2014 - 09/2015, Algiers, Algeria
University-Based Hospital
Pediatrics training : Emergency room duties, pediatric hematology/oncology and nephrology, adolescent care, conducted physical examination,
General Surgery training : Emergency room duties, attended operating room procedures, direct inpatients care (history, physical examination, work up), basic surgical skills
Internal Medicine training : Emergency room duties, direct inpatients care (history, physical examination, work up), attended medical conferences, discussed patients cases
Achievements/Tasks
Achievements/Tasks
Project description:
Hands on Clinical experience
April 10, 2025 Page 4 of 6
WORK EXPERIENCE
Intern
Obstetric and Gynecology Clinic GHARAFA
09/2014 - 12/2014, Algiers, Algeria
University Based Clinic
Obstetrics and Gynecology training: Emergency Room duties, labor, delivery, recovery and postpartum care, direct inpatients care
(history, physical examination, work up)
SKILLS
Wet-Laboratory
skills:
In vivo animal studies, cell culture, scRNA seq, flow cytometry, cytokine analysis, killing assay, protein quantification, transfection, multiplex immunoassays for cytokines. Data analysis: Pattern recognition, multivariate analysis, statistical analysis (GraphPad) Public speaking
and
communication
skills:
Numerous presentations were made at 1) our weekly meetings with our Laboratory team members, 2) conferences, and 3) institutional meetings with potential collaborators. Built and sustained long-term professional relationships. Project
management and
interpersonal
skills:
Established collaborative work involving multiple parties (researchers, surgeons, oncologists, nurses, administrative staff ...) where I had to discuss, coordinate, plan, and establish a pipeline for different projects. Leadership and
conflict
resolution:
I led different project initiatives involving individuals from various backgrounds, and I had to accommodate their communication styles and adapt to changing situations. EDUCATION
United States Medical Licensing Examinations
Kaplan Test Prep
05/2018 - 12/2018, New York, NY
USMLE step 2 Clinical Knowledge
United States Medical Licensing Examinations
Kaplan Test Prep
11/2016 - 01/2018, New York, NY
USMLE step 1
Doctor of Medicine
Université d'Alger Benyoucef Benkhedda Faculté des Sciences Médicales 10/2008 - 09/2015, Algiers, Algeria
Doctor of Medicine
ACHIVEMENTS
Job promotion: (04/2022)
I have been promoted from a Senior Research Technician to a Research Assistant. Mayoral Service Recognition Program: (2019)
I was awarded a certificate of recognition signed by the Mayor of the City of New York, Mr. Bill de Blasio, for my commitment, dedication, and volunteerism to strengthen my community after volunteering at Maimonides Medical Center. Hands on clinical experience
Health/Medical preparatory program:
Health/Medical preparatory program:
Degree :
April 10, 2025 Page 5 of 6
ACHIVEMENTS
Passed USMLE step 2 Clinical Knowledge (06/2019)
score : 223
passed USMLE step 2 Clinical Skills (05/2019)
passed USMLE step 1 : (05/2018)
score : 238
Graduation (Doctor of Medicine) (09/2015)
VOLUNTEER EXPERIENCE
Clinical Research Coordinator for the Grail Study: Weill Cornell Medicine / New York Presbyterian
08/2023 - 09/2024, NYC, USA
Enrollment of patients into this study with the objective is to validate this blood test as a Multi-Cancer Early Detection Test which allows patients to be screened for a shared signal by more than 50 cancer types, increasing the chance of finding cancer early. Contact : Dr. Cora Sternberg - *******@***.*******.*** Clinical observer at Dr. Wolchok's outpatient clinic Memorial Sloan Kettering cancer Center
08/2022 - 09/2023, NYC, USA
melanoma outpatient clinic
Shadowing Dr. Wolchok while he is taking care of his patients. asking questions, and discussing the different treatment options. Contact : Dr. Jedd Wolchok - *******@***.*******.*** Clinical observer at Dr. Ashfaq Marghoob's outpatient clinic Memorial Sloan Kettering Cancer Center
05/2023 - 10/2023, NYC, USA
Dermatology Clinic
learning how to describe cutaneous lesions using polarized light dermatoscope then discussing the differential diagnosis. Contact : Dr. Ashfaq Marghoob - ********@*****.*** Clinical observer at Dr. Chow's outpatient clinic
Memorial Sloan Kettering Cancer Center
07/2021 - 10/2021, NYC, USA
thoracic oncology clinic / inpatient rounds
Shadowing Dr. Chow while he is taking care of his patients. asking questions, participate in giving the differential diagnosis for each patient's main complaint and discuss the different treatment options. Contact : Dr. Andrew Chow - **********.*****@*****.*** Clinical observer
Maimonides Medical Center
01/2019 - 01/2019, NYC, USA
Hospital based in Brooklyn, New York City, NY, USA hardworking, took initiative, good cooperation with staff, good interaction with patients. Recognition letter signed by the Mayor of NYC: Mr. Bill De Blasio. Contact : Dr Hiba ALI - ********@*****.***
Tasks/Achievements
Tasks/Achievements
Tasks/Achievements
Tasks/Achievements
Tasks/Achievements
April 10, 2025 Page 6 of 6
VOLUNTEER EXPERIENCE
Medical Scribe
Artisans of Medicine NYC
07/2019 - 11/2019, NYC, USA
Brooklyn, NY
I accompany Dr. Joudeh while caring for his patients, asking questions, giving the differential diagnosis for each patient's main complaint, and discussing the different treatment options.
I gathered the patient's medical history, observed the physical examination performed by Dr. Joudeh, and completed the patient note once the visit concluded and the treatment plan was reviewed. Contact : Dr. Ramsey JOUDEH
LANGUAGES
Berber
languages
Arabic
French English
Tasks/Achievements
Contact this candidate