Data Science Artificial Intelligence

Tomas Drgon, page # *

Curriculum Vitae of Tomas Drgon PhD

CURRENT:

**** – present:

Data Scientist

Dataforward – Data Science Education Program Lead

Office of Digital Transformation (ODT)

Office of the Commissioner (OC)

U.S. Food and Drug Administration

Phone: 443-***-****

Email: *****.*****@***.***.***

2016 – present:

Guest Lecturer

Data Science, Artificial Intelligence, Machine Learning, Regulatory Science Dpt. Of Biochemistry and Molecular & Cellular Biology Georgetown University

DAILY DUTIES:

- Leads FDA data science education program (Dataforward)

- Leads team that develops the Dataforward data science curriculum

- Leads efforts on prioritization and risk assessment of data science projects

- Leads the development of data science solutions for urgent FDA data problems

- Advises FDA staff on applying data science to solve FDA regulatory and operational problems

- Works closely with Booz Allen Hamilton and Deloitte contract staff in development of data solution to cutting edge FDA data and AI problems

- Works with computational infrastructure teams to update the FDA IT system capabilities to be able to tackle modern and emerging data science problems

- Provides expert advice to FDA leadership on data science horizon scanning and policy issues regarding the employment of data science methods at the FDA and DHHS

- Develops guidance on best practices in the application of data science methods in regulatory science

- Serves as a liaison between data scientists, policy experts, medical professionals, representatives of the industry

- Leads cross-Center FDA wide data science, machine learning, and artificial intelligence workgroups

- Uses modern analytic tools such as R, Python, and works with analysts using SAS, SQL, Tableau, powerBI and others to address FDA data problems

- Participates in cross agency and industry data science workgroups (Interagency R group, Rgovys, ISPE GAMP Blockchain Interest Group) EDUCATION:

PhD biochemistry and molecular biology (1994)

Department of Biochemistry, Comenius University, Bratislava, Slovakia BSc/MSc chemical engineering (1983-1987)

Department of Food Technology, Slovak University of Technology, Bratislava, Czechoslovakia

Tomas Drgon, page # 2

LEADERSHIP, EXPERIENCE AND INTERESTS:

Dataforward: FDA-wide data science upskilling program FDA Scientific Computing Board - member

Data science driven program analysis and evaluation: drugs, medical devices, food, biotechnology, workforce models and resource allocation, risk analysis, effort prioritization.

FDA Data Science Workgroups:

- FDA Modeling and Simulation Workgroup (ex-chair, now co-chair)

- FDA Data Science Council (member)

- Artificial Intelligence Workgroup

Inter-agency/Industry Data Science Workgroups:

- R Validation Hub (R Consortium workgroup)

- ISPE GAMP Special Interest Group for Blockchain (ispe.org)

- Interagency R group (BLS, CDC, EPA, USGS, BLS, USDA, ASP, SEC, AHRQ, DHS, Census Bureau, and FDA)

- BioCompute Objects Project

Scientific Review (CSR/NIH):

- Tobacco Regulatory Science

- Neural Basis of Psychopathology, Addictions and Sleep Disorders (NPAS)

- Brain Phenotypes Special Emphasis Panels

Other interests: Data science, regulatory science, science policy, quantitative policy models and evaluation, peer review, conflict of interest, Prospect Theory and behavioral economics, biostatistics, AI/ML, LLM, bioinformatics, systems sciences, systems biology, genomics, behavioral and psychiatric genetics LEADERSHIP TRAINING:

FDA: Potential Supervisors Program (2023)

Leading with Impact (OD201) August 15 – 26 2022

Soft Skills for Professionals (MG132) October 22-24 2019 StrengtsFinder/CliftonStrengths workshop, July 31 – August 1 2018 Soft Skills for ORA Professionals December 6-8 2016 Change Management (Course ID OD105) July 28 2016

NIH: Excellent Leadership (2013)

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PROFESSIONAL EXPERIENCE:

2014 – 2024: Program Analyst

Office of Regulatory Affairs

FDA, Silver Spring MD

Daily duties:

- Led efforts in program evaluation and program analysis in all FDA commodity areas, with a special focus on foods, work planning, audits, inspections, sampling plans, and data science education. Chaired the FDA Modeling and Simulation Workgroup, and participated in outreach and education efforts in collaboration with the FDA Office of Chief Scientist.

2010 - 2014: Scientific Review Officer

Center for Science Review

NIH, Bethesda MD

Daily duties:

- Organized NIH peer review of broad range of data science grant applications including biostatistics, research design, system sciences, data science models of social behavior, tobacco regulation research, small business research initiatives.

- Advised grant applicants and made sure that the grants subject matter matched the data science scope of the funding proposals.

- Participated in the development of data science funding mechanisms.

- Used data science analytic tools such as R, Python, SAS, and SQL to match grant applications with reviewers with appropriate data science expertise. 2001 – 2010: Staff fellow

National Institute on Drug Abuse

NIH, Baltimore MD

Daily duties:

- Performed human genetic data collection and analyzed collected data with data science methods such as Principal Component Analysis, Hierarchical Clustering, Bayesian Networks, Network Analysis, and Monte Carlo methods.

- Used data analytic tools such as R, Python, SAS, Perl, and custom Bayesian Networks software to analyze data on daily basis.

- Developed and validated data science methods for analysis of human genetic data

- Co-authored papers on data science analysis of human clinical trials in psychiatric genetics and substance dependence.

1999 – 2001: Research associate

Center of Marine Biotechnology

University of Maryland Biotechnology Institute, Baltimore, MD Research: environmental health policy, environmental molecular biology 1994 – 1999: Postdoctoral fellow

NIDDK

NIH, Bethesda, MD

Research: morphogenesis and polarity development in eukaryotic cells 1990 - 1994: Ph.D. student

Department of Biochemistry, Comenius University, Bratislava, Slovakia Research: mitochondrial function and biogenesis.

1992 - FEBS/Swiss National Science Foundation Fellow Biozentrum, University of Basel, Basel, Switzerland 1989 - 1990 Graduate research fellow

Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Czechoslovakia 1989: Graduate research fellow

Food Industry Research Center, Bratislava, Czechoslovakia Tomas Drgon, page # 4

PEER REVIEW:

NIH grant reviewer in following study sections and Special Emphasis Panels: 1. Tobacco Centers of Regulatory Science ZRG1 ICN-R (50) (Jan 2023) 2. Cognitive and Neuropathological Signatures of Alzheimer's Disease, Brain Injury and Aging ZRG1 BDCN-W (02) M (Aug 2021)

3. Neuropsychiatric Disorders ZRG1 BDCN-J (02) M (July 2021) 4. Special Topics in Aging: Falls and Frailty, Diet, Inflammation and Hydrocephalus ZRG1 BDCN-W (91) S (Dec 2020)

5. Secondary Data Analyses to Explore NIMH Research Domain Criteria ZRG1 BDCN-J (55) R - PAR17-158 (July 2020)

6. Neural Basis of Psychopathology, Addictions and Sleep Disorders (NPAS) (Feb 2020) 7. Special Topics in Aging: Frailty, Deliurm, Immunosenescence, Cognition, and Alzheimer's Disease ZRG1 BDCN-W (92) S (Aug 2019)

8. Neural Basis of Psychopathology, Addictions and Sleep Disorders (NPAS) (June 2019) 9. Role of Mitochondria or Insulin Sensitivity in Aging ZRG1 BDCN-W (91) (March 2019) 10. Neural Basis of Psychopathology, Addictions and Sleep Disorders (NPAS) (Feb 2019) 11. Neural Basis of Psychopathology, Addictions and Sleep Disorders (NPAS) (Oct 2018) 12. Tobacco Centers of Regulatory Science ZRG1 IFCN-L (40) P (2018) FDA project peer review:

AI Spark Tank – Artificial intelligence solutions to FDA data problems (2025) Broad Agency Announcement: Regulatory Science Extramural Research and Development Projects (2015 - present)

TEACHING AND MENTORSHIP:

2024 – cont: Dataforward data science education program - lead 2019 – cont: Modeling and Simulation Office Hours – FDA-wide data science tutorial program – founder/administrator/lecturer

2018 – cont: Department of Biochemistry and Molecular & Cellular Biology, Georgetown University, MSc program in Biotechnology – guest lecturer – data science, artificial intelligence, machine learning, regulatory science 2018 SixSigma Lean - Instructor (Chapter 24 – Design of Experiments) 2010 – 2014: Center for Science Review, NIH: Outreach on grant writing and peer review. 2001 – 2010: Mentorship:

- Minority Recruitment and Training Program (NIDA).

- Physicians Training and Research Program (Temple University).

- Fogarty International Center Visiting Postdoctoral Fellowship program.

- MSc program at Johns Hopkins University School of Medicine. 1992 – 1994: Comenius University: undergraduate courses, tutorials and labs in biochemistry and molecular biology.

Tomas Drgon, page # 5

FELLOWSHIPS AND AWARDS:

FDA Commissioners Community Service Award – For student mentorship in aimHi program

(2024)

FDA Honor Award – For innovative and strategic approaches to advance the foods program’s economic adulteration initiatives and significant accomplishments with limited resources (2024), FDA Honor Award - For creating a cross-center forum to inform and discuss data science fundamentals that underlie artificial intelligence and its implications to the regulatory environment (2024)

ORA Honor Award – Implementation of Standardized Recall Audits (2022), FDA Commissioner Recognition Award – COVID19 FDA Level Advisory (2021), FDA Commissioner Recognition Award – Human and Animal Food Inventory Analysis (2019), FDA Office of Commissioner Honor Award (2018), FDA

Leveraging Collaboration Award (2016), FDA

NIH Directors Award – Addiction genetics workshop (2014), NIH Excellent University (2008) Speaking tour sponsored by the European Social Fund (EU), Bratislava, Slovakia.

NIDA Director’s Award of Merit (2005), NIH

Fogarty fellowship (1994-1999), NIH

FEBS fellowship (1992), University of Basel, Basel, Switzerland Swiss National Science Foundation Fellowship, 1992, University of Basel, Basel, Switzerland Tomas Drgon, page # 6

LIST OF PAPERS:

1. Riaz Ahmed KB, Pathmanathan P, Kabadi SV, Drgon T, Morrison T (2023) Annals of Biomedical Engineering 51: 6 - 9 Editorial on the FDA Report on Successes and Opportunities in Modeling & Simulation for FDA

2. Kasturi KN and Drgon T (2017) Applied and Environmental Microbiology 83: e00644-17 Evaluation of a Real-time PCR Method for Detection of Salmonella spp in Environmental Samples

3. Lee CT, Bendriem RM, Kindberg AA, Worden LT, Williams MP, Drgon T, Mallon BS, Harvey BK, Richie CT, Hamilton RS, Chen J, Errico SL, Tsai SY, Uhl GR and Freed WJ

(2015) Cell Reports 10: 616-636, Functional Consequences of 17q21.31/WNT3-WNT9B Amplification in hPSCs with respect to Neural Differentiation 4. Lee CT, Kindberg AA, Bendriem RM, Drgon T, Mallon BS, Uhl GR, Freed WJ (2014) Cell Transplantation 23: 776, Identification of 17q21. 31/WNT3-WNT9B Amplification Related to Accelerated Mesodiencephalic Dopaminergic Differentiation of Human Pluripotent Stem Cells

5. Uhl GR, Walther D, Drgon T (2013) Genetics of Substance Use, Abuse, Cessation, and Addiction: Novel Data Implicate Copy Number Variants, In: The Effects of Drug Abuse on the Human Nervous System, Eds: Madras B, Kuhar M, Academic Press, eBook ISBN: 978**********

6. Uhl GR, Drgon T (2012) Drug Abuse and Addiction in Medical Illness, pp 95-105, Springer New York, ISBN 978-1-4614-3375-0

7. Johnson C, Drgon T, Walther D, Uhl GR (2011) PLoS One 6(7):e19210 Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence

8. Drgon T, Johnson C, Nino M, Drgonova J, Walther D and Uhl GR (2011) Am J Med Genet B Neuropsychiatr Genet 156:125-38, Replicated genome wide association for dependence on illegal substances: genomic regions identified by overlapping clusters of nominally positive SNPs

9. Uhl GR, Drgon T, Johnson C, Ramoni MF, Behm FM and Rose JE (2010) Molecular Medicine 16:513-26, Genome wide association for smoking cessation success in a trial of precessation nicotine replacement

10. Rose J, Behm FM, Drgon T, Johnson C and Uhl GR (2010) Molecular Medicine 16:247-53 Personalized smoking cessation is informed by pre-cessation smoking and interactions between nicotine dose, dependence and “quit success” genotype scores 11. Drgon T, Zhang PW, Johnson C, Walther D, Hess J, Nino M and Uhl GR (2010) PLoS ONE 5:e8832, Genome wide association for addiction: replicated results using two analytic approaches

12. Uhl GR, Drgon T, Johnson C, Walther D, Aveyard P, Murphy M, Johnstone EC and Munafo M (2010) Pharmacogenomics 11:357-67, Genome wide association for smoking cessation success: participants in the patch in practice trial of nicotine replacement 13. Uhl GR, Drgon T (2010) Genetic contributions to individual differences in vulnerability to addiction and abilities to quit, In: Drug Abuse and Addiction in Medical Illness: Causes, Consequences, and Treatment; Eds: Verster JC, Brady K, Galanter M, Conrod PJ, Humana Press (ISBN-10: 160*******, ISBN-13: 978-1603275156) 14. Uhl GR, Drgon T, Johnson C, Liu QR (2010) Vulnerability to Substance Abuse, In: Addiction Medicine: Science and Practice,Ed: Johnson BA, Springer (ISBN: 978-1-4419- 0337-2)

15. Drgon T, Johnson C, Walther D, Albino AP, Rose JE and Uhl GR (2009) Molecular Medicine 15:268-274, Genome wide association for smoking cessation success: participants in a trial with adjunctive denicotinized cigarettes Tomas Drgon, page # 7

16. Uhl GR, Drgon T, Li CY, Johnson C, Liu QR (2009) Drug Alcohol Depend 104 Suppl 1:S58-63, Smoking and smoking cessation in disadvantaged women: assessing genetic contributions (review)

17. Johnson C, Drgon T, McMahon FJ and Uhl GR (2009) Am J Med Genet B Neuropsychiatr Genet 150:182-90, Convergent genome wide association results for bipolar disorder and substance dependence

18. Drgon T, Montoya I, Johnson C, Liu QR, Walther D, Hamer D and Uhl GR (2009) Molecular Medicine 15:21-27, Genome wide association for nicotine dependence and smoking cessation success in NIH research volunteers 19. Uhl GR, Drgon T, Johnson C and Liu QR (2009) J Neurogen 23:272-82, Addiction genetics and pleiotropic effects of common haplotypes that make polygenic contributions to vulnerability to substance dependence. (review)

20. Uhl GR, Drgon T, Johnson C and Rose J (2009) Pharmacogen J. 9:111-5, Nicotine abstinence genotyping: assessing the impact on smoking cessation clinical trials 21. Johnson C, Drgon T, Liu QR, Zhang PW, Walther D, Li CY, Ding Y, Anthony J, Eaton W and Uhl GR (2008) BMC Med Genet. 9:113, Genome wide association for substance dependence: convergent results from epidemiologic and research volunteer samples 22. Uhl GR, Drgon T, Johnson C, Li CY, Hess J, Naiman D and Liu QR (2008) Molecular genetics of addiction and related heritable phenotypes: genome wide association approaches identify “connectivity constellation” and drug target genes with pleiotropic effects. GR Uhl ed In: Addiction Reviews 1141:318-381, Annals of the New York Academy of Sciences, New York. (review)

23. Uhl GR, Liu QR, Drgon T, Johnson C, Walther D, Rose JE, David SP, Niaura R and Lerman C (2008) Arch Gen Psychiatry 65:683-693, Molecular genetics of successful smoking cessation: convergent genome-wide association results 24. Schmidt M, Drgon T, Bowers B, Cabib E. (2008) FEMS Yeast Res. 8:362-73, Hyperpolarized growth of Saccharomyces cerevisiae cak1 (P212S) and cla4 mutants weakens cell walls and renders cells dependent on chitin synthase 3 25. Uhl GR, Drgon T, Liu QR, Johnson C, Walther D, Komiyama T, Harano M, Sekine Y, Inada T, Ozaki N, Iyo M, Iwata N, Yamada M, Sora I, Chen CK, Liu HC, Ujike H, Lin SK. (2008) Arch Gen Psychiatry 65:345-55, Genome-wide association for methamphetamine dependence: convergent results from 2 samples

26. Uhl GR, Drgon T, Johnson C, Fatusin OO, Liu QR, Contoreggi C, Li CY, Buck K, Crabbe J

(2008) Biochem Pharm 75:98-111, “Higher order” addiction molecular genetics: convergent data from genome-wide association in humans and mice. (review) 27. Hishimoto A, Liu QR, Drgon T, Pletnikova O, Walther D, Zhu XG, Troncoso JC, Uhl GR.

(2007) Hum Mol Genet 16:2880-91, Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms 28. Saito K, Drgon T, Krupatkina DN, Drgonova J, Terlizzi DE, Mercer N, Vasta GR. (2007) Appl Environ Microbiol 73:6410-20, Effect of biotic and abiotic factors on the in vitro proliferation, encystment, and excystment of Pfiesteria piscicida 29. Uhl GR, Liu QR, Drgon T, Johnson C, Walther D and Rose J (2007) BMC Genetics 8:10, Molecular genetics of nicotine dependence and abstinence: Whole genome association studies with 520,000 SNPs

30. Liu QR, Drgon T, Johnson C, Walther D, Hess J and Uhl GR (2006) Am J Med Genet B Neuropsychiatr Genet 141:918-25, Addiction molecular genetics: 639,401 SNP whole genome association reveals many “cell adhesion” gene variants 31. Drgon T, D’Addario C and Uhl GR (2006) Am J Med Genet B Neuropsychiatr Genet 141:844-53, Linkage disequilibrium, haplotype and association studies of a chromosome 4 GABA receptor gene cluster: candidate gene variants for addictions 32. Johnson C, Drgon T, Liu QR, Walther D, Edenberg H, Rice J, Foroud T and Uhl GR (2006) Am J Med Genet B Neuropsychiatr Genet 141:844-53, Pooled association genome scanning Tomas Drgon, page # 8

for alcohol dependence using 104,268 SNPs: Validation and use to identify alcoholism vulnerability loci in unrelated individuals from the Collaborative Study on the Genetics of Alcoholism

33. Drgon T, Lin Z, Wang GJ, Fowler J, Kouzmenko A, Pablo J, Mash DC, Volkow N and Uhl GR (2006) Cellular and Molecular Neurobiology 26:875-89, Common human 5’ dopamine transporter (SLC6A3) haplotypes yield varying expression levels in vivo 34. Liu QR, Drgon T, Walther D, Johnson C, Poleskaya O, Hess J, Uhl GR. (2005) Proc Natl Acad Sci U S A. 2005 102:11864-9, Pooled association genome scanning: validation and use to identify addiction vulnerability loci in two samples 35. Lin Z, Walther D, Yu XY, Li S, Drgon T, Uhl GR. (2005) Hum Mol Genet.14:1393-404, SLC18A2 promoter haplotypes and identification of a novel protective factor against alcoholism

36. Liu QR, Walther D, Drgon T, Polesskaya O, Lesnick TG, Strain KJ, de Andrade M, Bower JH, Maraganore DM, Uhl GR (2005) Am J Med Genet B Neuropsychiatr Genet. 134:93-103, Human brain derived neurotrophic factor (BDNF) type 1 and type 2 genes, splicing patterns and assessments of associations with substance abuse and Parkinson’s disease 37. Drgon T, Saito K, Gillevet PM, Sikaroodi M, Whitaker B, Krupatkina DN, Argemi F, Vasta GR (2005) Appl. Environmental Microbiol 71:519-529, Characterization of Ichthyocidal Activity of Pfiesteria piscicida: Dependence on the Dinospore Cell Density 38. Lin Z, Walther D, Yu XY, Drgon T, Uhl GR (2004) Pharmacogenetics 14:805-11, The human serotonin receptor 2B: coding region polymorphisms and association with vulnerability to illegal drug abuse

39. Schmidt M, Varma A, Drgon T, Bowers B and Cabib E (2003) Mol. Biol. Cell 14:2128- 2141, Septins, under Cla4p regulation, and the chitin ring are required for neck integrity in budding yeast

40. Saito K, Drgon T, Robledo JAF, Krupatkina DN and Vasta GR (2002) Appl. Environmental Microbiol. 68:5394-407, Characterization of the rRNA locus of Pfiesteria piscicida and development of standard and quantitative PCR-based detection assays targeted to the nontranscribed spacer

41. Quesenberry MS, Saito K, Krupatkina DN, Robledo JAF, Drgon T, Pecher WT, O’Leary N, Alavi M, Miller T, Schneider RE, Belas R, Deeds JR, Place AR, Zohar Y and Vasta GR

(2002) J. Appl. Phycol. 14:241-254, Bioassay for Ichthyocidal Activity of Pfiesteria piscicida: Characterization of a Culture Flask Assay Format 42. Crotti LB, Drgon T and Cabib E (2001) Anal. Biochem. 292:8-16, Yeast Cell Permeabilization by Osmotic Shock Allows Determination of Enzymatic Activities In Situ 43. Drgonova J, Drgon T, Roh D-H and Cabib E (1999) J. Cell Biol. 146:373-387, The GTP- binding Protein Rho1p is Required for Cell Cycle Progression and Polarization of the Yeast Cell

44. Cabib E, Drgonova J and Drgon T (1998) Annual Review of Biochemistry 67:307-333, Role of Small G-proteins in Yeast Cell Polarization and Wall Biosynthesis (review) 45. Cabib E, Drgon T, Drgonova J, Ford RA and Kollar R (1997) Biochemical Society Transactions 25:200-204, The Yeast Cell Wall, a Dynamic Structure Engaged in Growth and Morphogenesis (review)

46. Drgonova J, Drgon T, Tanaka K, Kollar R, Chen G-Ch, Ford RA, Chan CSM, Takai Y and Cabib E (1996) Science 272:277-279, Rho1p, a Yeast Protein at the Interface Between Cell Polarization and Morphogenesis

47. Lohret TA, Murphy RC, Drgon T and Kinnally KW (1996) J.Biol.Chem 271:4846-4849, Activity of the Mitochondrial Multiple Conductance Channel is independent of the Adenine Nucleotide Translocator

48. Drgon T, Sabova L, Gavurnikova G and Kolarov J (1992) FEBS Letters 304:277-280 Yeast ADP/ATP Carrier (AAC) Proteins Exhibit Similar Enzymatic Properties, but their Deletion Produces Different Phenotypes

Tomas Drgon, page # 9

49. Drgon T, Sabova L, Nelson N and Kolarov J (1991) FEBS Letters 289:159-162 ADP/ATP Translocator is Essential only for Anaerobic Growth of the Yeast S. cerevisiae. SELECTED ABSTRACTS AND PRESENTATIONS:

1. Drgon, T (2023) (invited) “Public Health Economic Aspects in Development and Evaluation of Sampling Strategies for Human Food.” in Hot Topic Session - Risk Assessment and Risk Management: Current Issues in Sampling and Analysis. AOAC Annual Meeting and Exposition August 25-30 New Orleans LA

2. Drgon T (2022) (invited) Artificial Intelligence and Machine Learning – Technologist’s Perspective Biotechnology Program, Georgetown University, October 5 2022, Washington DC 3. Drgon T (2020) (invited) FDA – History, Structure, Law – Biotechnology Program, Georgetown University, April 27 2020, Washington DC

4. Drgon T (2019) (invited) FDA – History, Structure, Law – Biotechnology Program, Georgetown University, April 29. 2019, Washington DC

5. Drgon T (2018) (invited) FDA – History, Structure, Law – Biotechnology Program, Georgetown University, April 30. 2018, Washington DC

6. Drgon T (2013) (invited) Peer-review at the NIH, Joint Statistical Meetings - American Statistical Association, August 3 – 8, Montreal, Canada

7. Drgon T (2012) (invited) Peer-review at the NIH, Institute on Systems Science and Health (ISSH) June 10-15, Washington University, St. Luis MO

8. Drgon T (2012) (invited) Peer-review at the NIH, Junior investigators’ grant writing workshop, ENAR, March 31, Washington DC

9. Uhl GR, Drgon T, Liu QR, Johnson C, Bolla K, Cadet JL, Rose J, Donna W and Nino M (2009) Convergent Genome-Wide Association Data for Cognitive Ability and Alzheimer's Disease Ann. of Neurology 66, pp: S56-S56 Suppl. 13

10. Drgon T, Johnson C, Rose J, Uhl GR (2009) (poster) Principal Component And Bayesian Network Analyses Of Genome Wide Association Results From Substance Dependence And Smoking Cessation Success Studies. WCPG 2009, November 4-8, San Diego CA 11. Uhl GR, Drgon T, Johnson C, Rose J (2009) (poster) Smoking Cessation Molecular Genetics. WCPG 2009, November 4-8, San Diego CA

12. Rose J, Behm FM, Liu QR, Drgon T, Johnson C, Walther D, Uhl GR (2009) A genotype-based v1.0 score can prospectively predict smoking cessation success Annual Meeting of the Society for Research in Nicotine and Tobacco April 27-30, Dublin, Ireland 13. Drgon T, Johnson C, Uhl GR (2009) (poster) Substance Abuse and Epigenetics, Emerging Evidence for Epigenomic Changes in Human Disease, March 16–17, NIH, Bethesda MD 14. Drgon T, Johnson C, Uhl GR (2008) (poster) Principal Component Analysis and Hierarchical Clustering in 500K and 6.0 Genome Wide Association Datasets, 58th Annual Meeting of the American Society of Human Genetics, Philadelphia, PA 15. Drgon T (2008) (invited) Genotyping of Pooled DNA on Affymetrix Microarrays, GOT Summit: Microarrays in Medicine, May 19-20, Boston MA

16. Drgon T (2008) (invited) Genetics of complex human traits; Excellent University (speaking tour, European Union Social Fund), April 9-19, Bratislava, Slovakia (host: Prof Jordan Kolarov) 17. Drgon T (2008) (invited) Genetics of substance abuse in humans; Excellent University (speaking tour, European Union Social Fund), April 9-19, Bratislava, Slovakia (host: Prof Jordan Kolarov) 18. Drgon T (2008) (invited)Genotype-epigenotype interactions in human narcolepsy. Excellent University (speaking tour, European Union Social Fund), April 9-19, Bratislava, Slovakia (host: Prof Jordan Kolarov)

19. Drgon T, Johnson C, Liu QR and Uhl GR (2007) (poster) Addiction molecular genetics: convergent data from genome-wide association in individuals with European, African and Asian heritages. World Congress on Psychiatric Genetics, October 7-11, New York City NY Tomas Drgon, page # 10

20. Drgon T (2006) (invited) Neuropsychopharmacology 31 Supp.1, S49 VMAT2: Imprinted Allelic Variation and Roles is Narcolepsy, Vulnerability to Amphetamine Dependence and Tetrabenazine Responses. American College of Neuropsychopharmacology (ACNP) 45th Annual Meeting, Hollywood, FL

21. Drgon T, Johnson C, Liu QR, Walther D, Edenberg H, Rice J, Foroud T and Uhl GR (2006) (poster) Pooled association genome scanning for alcohol dependence using 104,268 SNPs: Validation and use to identify alcoholism vulnerability loci in unrelated individuals from the Collaborative Study on the Genetics of Alcoholism. 56th Annual Meeting of the American Society of Human Genetics, New Orleans LA

22. Hishimoto A, Drgon T, Zhu XG and Uhl GR (2005) (poster) Correlations of vesicular monoamine transporter 2 (VMAT2) methylation levels and tetrabenazine responses. 55th Annual Meeting of the American Society of Human Genetics San Diego CA

23. Takahashi M, Drgon T, Walther D, Lin Z, Lin L, Tafti M, Billiard M, Thorpy M, Temple H, Montplaisir J, Mignot E and Uh1 GR (2004) (poster) Vesicular monoamine transporter 2

(SLC18A2) in narcolepsy: Maternally-derived haplotypes are selectively transmitted and methylated with sequence-, haplotype- and parent-of-origin selectivity. Annual Meeting of the American Society for Neuroscience, Washington DC

24. Drgon T, Takahashi M, Walther D, Lin Z, Lin L, Tafti M, Billiard M, Thorpy M, Temple H, Montplaisir J, Mignot E, Uhl GR (2003) (poster) Narcolepsy: involvement of imprinted, differentially-methylated promotor haplotypes of vesicular monoamine transporter 2 (VMAT2). American Journal Of Human Genetics 73 (5): 949 Suppl, 53rd Annual Meeting of the American Society of Human Genetics, November 4-8, 2003, Los Angeles CA 25. Uhl GR, Liu Q-R, Ishiguro H, Gong JP, Zhu X, Drgon T, Drgonova J, Zhang PW, Lin Z, Polesskaya O and Walther D. (2002) (poster) Human Substance Abuse Vulnerability Loci: Identification and Initial Fine Mapping Studies, American Journal Of Human Genetics 71 (4): 1768 Suppl., 52nd Annual Meeting of the American Society of Human Genetics, October 15-19, Baltimore MD

26. Drgon T, Krupatkina DN, Drgonova J and Vasta GR (2000) (poster) Growth Characteristics of Clonal Pfiesteria piscicida in Culture (abstract B3) CDC National Conference on Pfiesteria: From Biology to Public Health October 18-20, 2000, Atlanta GA 27. Drgon T, Saito K, Krupatkina DN, Berard C, Place AR, Kubanek J, Baden DG and Vasta GR (2000)

(poster) Fish Bioassay for Pfiesteria piscicida Toxicity: A Preliminary Comparative Study of Culture Flask and Tank Assay Formats (abstract M4), CDC National Conference on Pfiesteria: From Biology to Public Health, October 18-20, 2000, Atlanta GA 28. Drgonova J, Schott EJ, Coss CA, Krupatkina DN, Drgon T and Vasta GR (2000) (poster) Characterization of Actins and Tubulins from the Heterotrophic Dinoflagellate Pfiesteria piscicida. Subcellular Localization by Immunofluorescence (abstract 110). Symposium on Harmful Marine Algae in the U.S. December 4-9, 2000, Marine Biological Laboratory, Woods Hole MA 29. Drgon T. (2000) (invited) Pfiesteria Hysteria: Harmful algal blooms in the US. Department of Biology, Shippensburg University, Shippensburg PA. Host: Dr. Richard Ford 30. Lohret TA, Murphy RC, Drgon T, Kinnally KW (1996) (poster) Evidence that the adenine nucleotide translocator is not responsible for the mitochondrial multiple conductance channel, MCC. Biophysical Journal 70: (2) TUAM2-TUAM2, Part 2 Biophysical Society Meeting, Baltimore MD 31. Drgonova J; Drgon T; Roh D-H and Cabib E (1996) (poster) The GTP-binding Protein Rho1p is Required for Cell Cycle Progression and Polarization of the Yeast Cell. Meeting of American Society for Developmental Biology University of California at Santa Cruz, Santa Cruz CA, 32. Lohret TA, Murphy RC, Drgon T, Kinnally KW (1995) (poster) Evidence That The Mitochondrial Multiple Conductance Channel, MCC, Is Not Related To The Adenine-Nucleotide Translocator, Molecular Biology Of The Cell 6: 2528-2528 Suppl. S, Meeting of the American Society of Cell Biology, Washington DC

33. Drgon T, Sabova L and Kolarov J (1994) (poster) Yeast ADP/ATP Carrier (AAC) Proteins Exhibit Similar Enzymatic Properties, but their Deletion Produces Different Phenotypes. Joint Meeting of Tomas Drgon, page # 11

the British Society for Cell Biology and the British Society for Developmental Biology, University of East Anglia, Norwich, Great Britain

34. Drgon T; Sabova L; Gavurnikova G and Kolarov J (1993) ADP/ATP Carriers in Yeast: Biosynthesis and Transcriptional regulation. Vienna Yeast Meeting, Institute of Molecular Pathology, Vienna, Austria, Host: Dr. Gustav Amerer 35. Drgon T, Sabova L and Kolarov J (1993) Transcriptional Regulation of the ADP/ATP Carrier Proteins in Yeast.

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