Histology Manager

Jesse Lee James Papp

Desert Hot Springs, California • *****.****.***@*****.*** • 530+305+2925 • in/Jessepapphtl SUMMARY

Accomplished histotechnology professional with a decades experience in optimizing lab operations while delivering patient-centered innovations. Adept at leading high-performing, cross-functional teams to advance diagnostic accuracy, reduce turnaround times, and foster a culture of excellence. Employs a first-principles approach alongside data-driven insights to achieve measurable, scalable outcomes in dynamic healthcare settings. EXPERIENCE

Histology Manager Neuralink Corp. Fremont, CA April 2021 - April 2023

• Boosted efficiency by 45% across facilities by optimizing workflows and integrating advanced automation protocols.

• Spearheaded the evaluation and procurement of novel digital pathology system, increasing per-run throughput by 1000% and reducing TAT by order of magnitude.

• Improved team productivity by 30% through cross-functional meetings that ensured transparency and KPI alignment.

• Reduced invalid QC results by 85% by implementing a novel, data-driven quality control system for IHC assays.

• Achieved 98% stakeholder satisfaction and ensured 100% GLP compliance with standardized SOPs and comprehensive training.

• Surpassed turnaround targets by 10% by streamlining technician coordination and scheduling across multiple locations.

• Designed and validated a comprehensive IHC program featuring antibody selection, assay optimization, and quantitative analysis.

• Developed multiplex detection methods that reduced slide burden by 66% while preserving tissue integrity.

• Established a biomarker surveillance program for TBI, correlating findings with IHC slides to advance preclinical research. Biosample Operations Specialist Verily Life Sciences South San Francisco, CA November 2019 - May 2020

• Managed logistics for a 5-year longitudinal clinical trial that contained over 3 million collected biospecimens of multiple sample types.

• Reduced study costs by $250,000 through fastidious analysis and negotiation of vendor contracts.

• Improved sample traceability with a digital tracking solution, leading to a 58% reduction in average sample procurement and recall times.

• Oversaw site/vendor contracts, ensuring cost efficiency and stakeholder engagement through transparent digital dashboards. Histotechnologist University of California, Davis Davis, CA March 2018 - April 2019

• Delivered high-throughput histology operations, including grossing, embedding, and staining.

• Optimized laboratory efficiency by 15% with a novel LIS software suite.

• Educated faculty and researchers on histology protocols and safety procedures.

• Built and standardized wet lab biology research protocols, streamlining specimen analysis to enhance diagnostic accuracy by 20% over a 6-month period.

• Managed set timelines for specimen processing, increasing lab output by 25% over 4 months through strategic planning and resource allocation. Molecular Diagnostics Core Manager California National Primate Research Center Davis, CA September 2016 - March 2018

• Managed molecular diagnostic core operations, ensuring 95% accuracy across all qPCR and ddPCR assays.

• Developed and validated novel protocols, advancing diagnostic capabilities of the center by 53%.

• Trained staff on LIMS systems, fostering a proficient laboratory environment that culminated in 37% less equipment scheduling conflicts. Histotechnician IDEXX Laboratories West Sacramento, CA July 2014 - September 2016

• Processed 2,500 samples daily in a high-volume laboratory environment, ensuring accurate results for veterinary clients worldwide.

• Maintained precision while managing complex workflows across multiple shifts, contributing to seamless operations in a fast-paced, setting.

• Optimized laboratory turnaround times by streamlining and implementing best practices, consistently exceeding client expectations. .

• Ensured compliance with rigorous quality standards by adhering to established protocols and conducting detailed quality control checks.

• Collaborated with a multidisciplinary team to ensure uninterrupted operations in a high-demand diagnostic environment.

• Trained and mentored new staff members, instilling a culture of excellence within the laboratory team. CERTIFICATIONS

Histotechnologist (HTL) American Society for Clinical Pathology 2019 Demonstrates advanced proficiency in histotechnology, including tissue preparation, staining, and analysis, ensuring accurate diagnostic and research results. Recognized for expertise in adhering to GLP standards, performing complex laboratory techniques, and maintaining quality assurance in clinical and research environments.

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PUBLICATIONS

In vitro and In vivo Susceptibility of Baboons (Papio sp.) to Infection with and Apparent Antibody Reactivity to Simian Betaretrovirus (SRV)

California National Primate Research Center pubmed.ncbi.nlm.nih.gov/31747991/ September 2016 - January 2018 Performed all wet lab procedures, including sample preparation, assay execution, and data collection, to evaluate susceptibility of baboons to Simian Betaretrovirus

(SRV).

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• Supported antibody reactivity analysis and contributed to the development of reproducible diagnostic methodologies for the study. EDUCATION

Bachelor of Science in Biological Sciences University of California, Davis 2014 SKILLS

Technical Skills: Advanced IHC and Tissue Staining, Automated IHC/ISH Techniques, Multiplexing Experiments, qPCR, ddPCR, Additive Manufacturing Regulatory Compliance: GLP, Quality Control and Assurance, EH&S Procedures Leadership: Team Management, Cross-Functional Collaboration, Project Oversight Software: LIMS, LIS, Digital Tracking Solutions, Microsoft Office, CAD Desigin

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