Laura Jean Hempleman

928-***-****

***** ******** ******* *** ****

San Diego CA 92128

adznnp@r.postjobfree.com

Graduate from Northern Arizona University with BS in Biological Sciences. Excellent time management skills that is able to adapt and learn in any situation. Dedication and interest in biological research. EDUCATION

2011-2015 Bachelor’s Degree in Northern Arizona University Biological Sciences

(December 18, 2015)

EMPLOYMENT

2022 (September)- Current

Crinetics Pharmaceuticals

Supervisor: Odalie Mamayson

Senior Research Associate, Toxicology

• Directly interface with contract research organizations (CROs) to request quotes and derive cost estimates, schedule and place studies, and oversee the generation and approval of contracts and subsequent invoicing

• Assist in the preparation, review, and/or finalization of study protocol and reports

• Coordinate shipping/receipt of test article and study-related samples to appropriate CROs

• Assist project toxicologists in analyzing and summarizing study data

• Track and maintain study specific and financial milestones

• Perform QC on toxicology and safety pharmacology sections of regulatory submissions (INDs, DSURs, IBs, and NDAs)

• Provide support to build and maintain different study databases 2018 (August)- 2022 (July)

Heron Therapeutics: Translational Science

Supervisor: Adrienne Griffith/ Dr. Clynn Wilker

Research Coordinator/Senior Research Coordinator (Dec 2019)/ Specialist –Pharmaceutical and Translational Sciences (Dec 2021)

• Assists with technical documents, including protocols, reports, CMC-related regulatory submissions.

• Manage NDAs, MSAs, Consulting Agreements, Requests for Proposals, and Statements of Work using Heron Contracts Management System.

• Collaborate with the Heron Legal Department and the Vendor Legal Department and assist with negotiations by email, as needed.

• Communicate directly with vendors to ensure that contracts are set up according to Heron practices.

• Request and manage purchase orders using iPurchase.

• Assist with tracking vendor invoices, as needed.

• Responsible for organization and maintenance of appropriate records (logbooks, inventories, and other spreadsheets).

• Write SOPs, test methods, and development reports.

• Upload, track and manage document workflows in Veeva RIM for the affiliated group and provide status updates.

• Data management in LIMS.

• Technical data review.

• Work with other groups to route, approve, issue and retain documentation.

• Organize and maintain a safe, efficient laboratory environment including equipment logs, calibration scheduling and inventories.

• Assist with QC review of regulatory submission documents.

• Verify Stability and Lot Release data in SLIM and Lot Release Tracker.

• Assign report numbers, and keep PharmSci documents up to date in Veeva. 2016 (September)- 2018 (August)

La Jolla Institute for Immunology

Supervisor: Dr. Anjana Rao/ Dr. Patrick Hogan

Laboratory Technician I/ Laboratory Manager (Promoted August 2017)

• Inform and help enforce lab policies

• Purchase reagents, negotiate discounts, and maintain inventory

• Work with the accounting department to manage invoices

• Write and amend Animal, Biohazard and Recombinant DNA protocols

• Help maintain common equipment and contact service when needed

• Track incoming and outgoing reagents and necessary MTA documentation

• Communicate with various administrative departments to make sure that the lab and its members are aware of institute policies and regulations

• Maintain a large and complex mouse colony, including breeding and genotyping

• Demonstrated proficiency in animal dissection, injections and tissue collection

• Demonstrated proficiency in basic and advanced tissue culture techniques

• Proven experience in accurate record keeping with ability to organize, analyze, and calculate data

• Superior oral and written communication skills

2016 (February)- 2016 (September)

The Scripps Research Institute

Supervisor: James Vestal/ Kelly Hall

Animal Care Technician I

• The daily care of research animals including feeding, cage washing, maintaining a clean environment and monitoring the overall health of the animals.

• Transfers animals from dirty to clean caging providing appropriate feed, water and bedding. Notify appropriate personnel of abnormal conditions.

• Conducts daily animal health observations and completes health reports identifying sick animals. Performs basic animal health treatments with direction from the veterinary staff.

• Cleans, sanitizes and autoclaves caging, equipment and refills water bottles. May also clean and replace excreta pans or pads. Receives feed, bedding, and supplies. Autoclaves feed, bedding, and cages in preparation for use.

• Maintains cagewash equipment including cleaning the screens, jets, and manifolds. Performs preventative maintenance such as descaling tanks and polishing machine. Reports maintenance needs to the appropriate personnel.

• Performs general housekeeping duties including but not limited to sweeping and mopping work areas and hallways. Properly disposes of waste. Euthanizes rodents according to written procedures. Performs other duties as assigned

2015 (May)- 2016 (January)

Northern Arizona University

Supervisor: Scott Nichols DVM

Animal Research Technician

• Responsible for monitoring animal health.

• Assess and remove animals from studies for health or safety reasons if needed.

• Know the requirements of each species housed.

• Know and teach proper handling techniques for each species.

• Monitor facility and investigator equipment, troubleshoot and contact appropriate personnel if problems occur. Monitor environmental conditions of animal holding rooms for appropriateness, with regard to species.

• Evaluate clinical signs

• Record keeping

2012 (March)- 2015 (November) Flanagan Stables

Supervisor: Christye Flanagan

Farm Manager

• Developing & enforcing feed & cleaning schedules, overseeing daily horse care

• Ordering supplies & feed

• Dispensing & applying prescribed medications and treatments

• Developing exercise routines

• Available for emergency after-hours

• Arranging and overseeing vet visits, worming & shots as well as other aspects of routine maintenance

PUBLICATIONS:

Chen, J.; Lopez-Moyado, I.F.; Seo, H.; Lio, C.J.; Hempleman, L.J.; Sekiya, T.; Yoshimura, A.; Scott- Browne, J.P.; Rao, A. NR4A transcription factors limit CAR T cell function in solid tumours. Nature 2019, 567, 530–534.

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