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Dr. Mahendar Lodi

+91-800******* adzmy2@r.postjobfree.com

Pallerla village, Atmakur Mandal, Yadadribhongiri District, Telangana, 500039

: I am an enthusiastic, self-motivated and self-learning person, seeking suitable and challenging career in a dynamic and rewarding research organization where my quality skills and knowledge can be utilized towards success and growth of the organization.

: Scientific Manager (Team Lead) March-2021-Present Aragen Life Sciences Hyderabad

• Supervised Team with 5-7 chemists (FTE) projects.

• Contributed and actively participated in research conception, route scouting, process development and execution to address defined problems.

• Interacted with clients and reported progress reports on weekly basis.

• Synthesized CRO molecules from mg to multi G scale.

• Interacted with clients on weekly basis by Tele/Video conferences.

Kothari Postdoctoral Fellow Nov-2019-Mar-2021

University of Hyderabad Hyderabad

• Developed an efficient and practically viable Lewis base catalyzed [2+3] cycloaddition protocol for the synthesis of fully substituted (E)-styrylthiophene with δ-acetoxy allenoates. Postdoctoral Research Fellow Jan-2017-Jan-2018

University of York United Kingdom

• Worked on the Synthesis of Cyclic Peptide Mimetics by the Successive Ring Expansion of Lactams.

Research Associate Nov-2015-Jan-2017

IIT Hyderabad India

• Developed methods for re-usable heterogeneous catalysis of Pd/Cu-doped on carbon nanomaterials (Carbon nanotubes

& graphite).

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Ph. D in Synthetic Organic Chemistry Jun-2010-Dec-2015 IIT Hyderabad India

Title of my thesis is “Transition Metal Catalyzed One-pot Domino Transformations: Synthesis of Novel Heterocyclic Compounds”. Prof. G. Satyanarayana

M.Sc. in Organic Chemistry 2006- 2008

Kakatiya University Warangal

First division with distinction

B.Sc. in Chemistry Zoology and Botany 2003- 2006

Osmania University Hyderabad

First division

• Awarded Dr. Kothari Postdoctoral Research Fellowship from UGC, India, 10/2019.

• Awarded Advanced Postdoctoral Research Fellowship, from University of Cyprus, Cyprus, 03/2019.

• Awarded Postdoctoral Research Fellowship from

POSTECH University, Pohang, South Korea, 09/2018.

• Awarded Postdoctoral Research Fellowship from The Hebrew University, Jerusalem, Israel, 08/2016.

• Awarded SERB-Overseas Postdoctoral Research

Fellowship (SERB-OPDF), DST, India, to peruse research in the University of York, York, United Kingdom 12/2016.

• Excellence in Research Award by IIT Hyderabad for the both year of 2014 and 2015.

• Awarded Junior Research Fellowship from the University Grants Commission (UGC), New Delhi, India, 07/2009.

• Expertise in design and executing multi-step synthesis of targeted organic molecules in short and efficient synthetic routes.

• Drug Discovery and Medicinal Chemistry.

• Expertise in the development of novel organic synthetic methodologies including C-H activation.

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• Interacted with clients and reported the progress on weekly basis.

• Efficient supervision of the team members.

• Capable of both collaborative and independent research.

• Experienced in working with international pharmaceutical R & D projects, high professional in reaching goals within time limits and standards.

• Effective communication and team management.

SERB-OPDF project:

Award No: SB/OS/PDF-158/2015-16

Title: Dial-a-Macrocycle: Designer Macrocycles via Successive Ring Expansion

Scaffolds: Application to Synthesis of Bioactive Molecules Grant amount: Rs. 26,99,090/- (Rupees twenty six lakhs 99 thousand ninety rupees only)

Oral Presentation given at Conference titled “(J-NOST) National Conference on Organic Synthesis -2014”,

organized by IIT Madras, on December 4-6, 2014.

Poster-Presented at Conference titled “Chemical Research Society of India (CRSI)-National Symposium” jointly organized by NIT Trichy and Bharathidasan University, during July 23-27, 2015.

Oral Presentation given at Dr. K.V. Rao Scientific Society Annual Research Awards 2014-15.

Poster Presentation at 2017 RSC Organic Division North East Regional Meeting held in the Department of Chemistry, Durham University, UK.

Poster Presentation in 2017 at JEOL Postdoc Poster Competition held in the Department of Chemistry, University of York, UK.

Date of birth: 04th July 1985

Marital status: Married

Permanent Address: Pallerla village, Atmakur Mandal, Yadadribhongiri District, Telangana, Pin cod e: 508111, India.

:

1. Evaluating the Viability of Successive Ring Expansions Based on Amino Acid and Hydroxyacid Side Chain Insertion

Aggie Lawer, Ryan G. Epton, Thomas C. Stephens, Kleopas Y. Palate, Mahendar Lodi, 4

Emilie Marotte, Katie J. Lamb, Jade K. Sangha, Jason M. Lynam and William P. Unsworth, Chem. Eur. J. 2020, 26, 12674.

2. Synthesis of Cyclic Peptide Mimetics by the Successive Ring Expansion of Lactams. Thomas C. Stephens, Mahendar Lodi, Andrew M. Steer, Yun Lin, Matthew T. Gill and William P. Unsworth, Chem. Eur. J. 2017, 23, 13314. 3. A domino palladium-catalyzed C-C and C-O bonds formation via dual O-H bond activation: Synthesis of 6,6-dialkyl-6H-benzo[c]chromenes. L. Mahendar, J. Krishna, A. G. K. Reddy, B. Venkatramulu and G. Satyanarayana, Org. Lett., 2012, 14, 628.

4. Substitution Controlled Functionalization of ortho-Bromobenzylic Alcohols via Palladium Catalysis: Synthesis of Chromenes and Indenols. L. Mahendar and G. Satyanarayana, J. Org. Chem., 2014, 79, 2059. 5. Domino [Pd]-Catalysis: One-pot Synthesis of Isobenzofuran-1(3H)-ones. L. Mahendar and G. Satyanarayana, J. Org. Chem., 2016, 81, 7685. 5

6. Domino One-Pot Process for the Synthesis of Isobenzofuran-1(3H)-ones via [Cu]- Catalysis Using Water as the Green Solvent.

L. Mahendar and G. Satyanarayana, J. Org. Chem., 2015, 80, 7089. 7. [Cu]-Catalyzed domino Sonogashira coupling followed by intramolecular 5-exo-dig cyclization: Synthesis of 1,3-dihydro-2-benzofurans. L. Mahendar, A. G. K. Reddy, J. Krishna and G. Satyanarayana, J. Org. Chem., 2014, 79, 8566.

8. [Cu]-Catalyzed Direct Coupling of Dibromoalkenes: Synthesis of Symmetrical 1,3- Diynes and Triazoles.

L. Mahendar, B.V. Ramulu and G. Satyanarayana, Synth. Commun. 2017, 47, 1151. 9. Nano-sized Recyclable PdO Supported Carbon Nanostructures for Heck Reaction: Influence of Carbon Materials.

B. Laxminarayana, L. Mahendar G. Satyanarayana and Ch. Subrahmanyam, ChemistrySelect, 2017, 2, 2703.

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10. Fabrication of Pd/CuFe2O4 hybrid nanowires: Heterogeneous catalyst for Heck couplings.

B. Laxminarayana, L. Mahendar, P. Ghosal,b B. Sreedhar, G. Satyanarayana and Ch. Subrahmanyam, New J. Chem. 2018, 42, 1646.

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11. Organic Transformations Catalyzed by Palladium Nanoparticles on Carbon Nanomaterials.

B. Laxminarayana, L. Mahendar G. Satyanarayana and Ch. Subrahmanyam, J. Chem. Sci. 2018, 130:47.

12. Copper Catalyzed Coupling of Protecting Group Free and Sterically Hindered 2- Bromobenzyl Tertiary Alcohols with Phenols and Anilines: Facile Synthesis of 7

Xanthenes and Dihydroacridines.

L. Mahendar and G. Satyanarayana, RSC Advances, 2016, 6, 20588. 13. Lewis Acid Catalyzed Mild Method for Head to Tail Dimerization or Cyclization of tert-Alcohols.

B.V. Ramulu, L. Mahendar and G. Satyanarayana, Asian J. Org. Chem. 2016, 5, 207. 14. Palladium-mediated highly regio- and stereoselective intermolecular -arylation on allylic alcohols: Synthesis of functionalized allylic alcohols. J. Krishna, A. G. K. Reddy, B. V. Ramulu, L. Mahendar and G. Satyanarayana, Synlett, 2012, 23, 375.

15. An efficient intermolecular [Pd]-catalyzed C–C and intramolecular [Cu]-catalyzed C–O bonds formation: synthesis of functionalized flavans and benzoxepine. B. Suchand, J. Krishna, B.V. Ramulu, D. Dibyendu, A. G. K. Reddy, L. Mahendar and G. Satyanarayana, Tetrahedron Lett., 2012, 53, 3861.

16. Simple, copper(I)-catalyzed oxidation of benzylic/allylic alcohols to carbonyl compounds: Synthesis of functionalized cinnamates in one pot. A. G. K. Reddy, L. Mahendar and G. Satyanarayana, Synth. Commun., 2014, 44, 2076. 17. Transition metals catalyzed C-C and C-O bonds formation: Facile synthesis of flavans and benzoxepines.

B.V. Ramulu, L. Mahendar, J. Krishna, A. G. K. Reddy and G. Satyanarayana, Tetrahedron, 2013, 69, 8305.

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Prof. G. Satyanarayana

Department of Chemistry

IIT Hyderabad, Kandi 502 285

Sangareddy, Telangana State, India.

Email: adzmy2@r.postjobfree.com

Tel: +91-40-230*-****

Dr. William P. Unsworth

Department of Chemistry

The University of York

Heslington, York.

United Kingdom, YO105DD

Email: adzmy2@r.postjobfree.com

Tel: (01904) 322596

Prof. Ch. Subrahmanyam

Department of Chemistry

IIT Hyderabad, Kandi 502 285

Sangareddy District, Telangana State, India.

Email: adzmy2@r.postjobfree.com

Tel: +91-40-230*-****

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