Maurizio V. Infante, MD

adzilo@r.postjobfree.com • Verona, Italy

+39-335-******* (M) • +39-045******* (W)

www.linkedin.com/in/maurizio-v-infante-b42a0519

Personal Details:

February 12, 1962 • Milan, Italy

Italian • Male • Married

Summary

Thoracic Surgery Consultant

Results-focused and compassionate surgeon with extensive experience across diverse practices including thoracic surgery and clinical research. Proven success in developing and implementing strategies to advance positive patient management outcomes, as well as industry priorities including effecting cost savings by utilizing lean management systems and organizational adjustments. Collaborative professional skilled at facilitating cross-functional teams with competing priorities to achieve maximum results with minimal resources. Demonstrated background of employing clinical and procedural innovations the increase departmental reputation. Analytical individual skilled at reviewing existing processes and identifying opportunities to enhance accuracy and overall efficiency. Fluent in Italian and English; limited conversational ability in Dutch.

Accomplishments

●I was the Coordinator and eventually the Principal Investigator of the DANTE trial, the first randomized trial to be launched in the world that compared lung cancer screening with spiral CT vs. no intervention in high-risk subjects. In this study 2452 subjects were recruited and followed for a median of 8.35 years. This effort led to the detection of 104 patients (8.23%) lung cancer cases in the screening arm (66 by CT), 47 of whom (3.71%) had stage I disease. I have been since a member of an international group that promotes the implementation of lung cancer screening. (Infante M, et al; DANTE Study Group. Long-term Follow-up Results of the DANTE Trial, a Randomized Study of Lung Cancer Screening with Spiral Computed Tomography. Am J Respir Crit Care Med 2015; 191 (10): 1166-1175. DOI: 10.1164/rccm.201408-1475OC)

●A collateral benefit of the the DANTE study was that it gave an impulse to the development and refinement of minimally invasive lung cancer surgery, that is nowadays the standard of care for early-stage lung cancer but was not so in the early 2000’s when the study was launched. I was eventually elected a member of the board of directors of the Italian VATS Group prospective registry and remained in charge until 2018. (for example please see: Infante MV, et al . What counts more: the patient, the surgical technique, or the hospital? A multivariable analysis of factors affecting perioperative complications of pulmonary lobectomy by video-assisted thoracoscopic surgery from a large nationwide registry. Eur J Cardiothorac Surg. 2019 Jun 30. pii: ezz187. doi: 10.1093/ejcts/ezz187)

●The development of lung sparing lung resection techniques (i.e. segmentectomy by VATS) is one of my achievements as I have successfully completed more than 100 VATS pulmonary segmentectomies with zero mortality and less than 10% morbidity, and developed technical tips and tricks to accomplish the procedure that have been presented at several national meetings since 2017

●Another accomplishment was the development and diffusion of lung nodule management protocols that have improved the outcomes for patients and are in use in the Hospitals where I have worked. (for example please see: Infante M, Berghmans T, Heuvelmans MA, Hillerdal G, Oudkerk M. Slow-growing lung cancer: an emerging entity. From screening to clinical management. European Respiratory Journal 2013; 42: 1706-1722. doi:10.1183/09031936.00186212., and Infante M. A conservative approach for subsolid lung nodules: is it safe enough? (Editorial). Eur Respir J. 2015 Mar;45(3):592-5. doi: 10.1183/09031936.00222914. No abstract available. PMID: 25726534. IF 7,636

●I have improved technical procedures for the management of early-stage and locally advanced mediastinal tumors (for example please see: Infante M, et al. VATS thymectomy for early stage thymoma and myasthenia gravis: combined right-sided uniportal and left-sided three-portal approach. J Vis Surg. 2017 18;3:144. doi: 0.21037/jovs.2017.09.01) and Campisi A et al. Giant thymoma with complete superior vena cava obstruction. Indian J Thorac Cardiovasc Surg. 2023 Jan;39(1):83-85. doi: 10.1007/s12055-022-01442-y.and Campisi A. et al Synchronous follicular dendritic cell sarcoma of the mediastinum and gynecological cancer: a case report. https://dx.doi.org/10.21037/shc-23-15

●I have perfected the surgical technique for the Nuss repair of pectus excavatum with approximately 300 cases successfully completed, two-thirds of whom are adults and with a low 1.8% bar displacement rate (Infante M, et al. What Is the Appropriate Timing for Bar Removal After the Nuss Repair for Pectus Excavatum? J Surg Res. 2023 May;285:136-141. doi: 10.1016/j.jss.2022.12.029.).

Career Experience

●

Head of Thoracic Surgery Department 2016 – Present

University and Hospital Trust, Verona, Italy

Direct a wide range of procedures inclusive of state-of-the-art comprehensive management of all thoracic conditions. Collaborate with multiple departments such as Spinal Surgery, Cardiac, and Head and Neck. Perform surgery for malignant pleural mesothelioma, pleural empyema, lung abscess, chest wall stabilization after major trauma in addition to esophagectomy-gastrectomy cases on upper GI patients. Carried out or assisted some 15 robotic major lung resections.

Coordinate the multidisciplinary thoracic oncology team on a weekly basis to discuss complex cases, including from neighbouring hospitals. On average, 10 to 15 cases are presented and 15 to 20 specialists and trainees attend the on-line meeting. This Multidisciplinary on-line group is considered the best-performing MDT in the University Hospital of Verona.

Oversaw the thymoma and myasthenia gravis multidisciplinary team until 2023.

●Completed approximately 1,000 major lung resections for cancer and/or MDR mycobacterial infections, as well as 250 mediastinal procedures and 70 VATS thymectomy for thymoma and/or myasthenia gravis.

●Managed a variety of chest-wall conditions and carried out resections for sarcoma or lung cancer invading the chest-wall, chronic infection, stabilization for trauma, and over 400 chest wall deformity cases

●Managed invasive lung cancer staging (videomediastinoscopy or mediastinotomy, EBUS),

●Effectively reduced the mean hospital stay after major lung resection from 9 days to 5.4 days on average and maintained perioperative mortality below 0.5% over the past few years.

Consultant Thoracic Surgeon / Head of Clinical Research Section 2004 – 2016

Humanitas Research Hospital, Milan Italy

Supervised the ward in the 720-bed tertiary referral centre. Conducted weekly chest surgery clinics, as well as clinical audits. Provided executive-level consultancy within the Emergency Department. Facilitated weekly cross-functional team meetings. Served as a member of the panel focused on the issuance and review of internal management guidelines for lung cancer, mesothelioma, and thymoma.

●Initiated an institutional pectus surgery program, VATS-lobectomy and VATS-thymectomy program.

●Promoted lung-sparing surgery and pleurectomy / decortication for mesothelioma which is now the standard approach for the department.

●Introduced improvements in the operative and postoperative care of esophageal cancer patients with enhanced recovery after surgery by effecting early administration of liquids and a soft diet per mouth resulting in a postoperative stay of less than ten days.

Additional Experience

Clinical Fellow in Thoracic Surgery, University Hospital Gasthuisberg, Leuven, Belgium

Thoracic Surgery Department, Humanitas Research Hospital, Milan, Italy

General Surgery, Bassini General Hospital, Milan Area, Italy

General Surgery, Abbiategrasso General Hospital, Milan Area, Italy

Thoracic Surgical Oncology, National Cancer Institute, Milan, Italy

Thoracic Surgical Oncology Department Resident, National Cancer Institute, Milan, Italy

Surgical Intensive Care Resident, University Hospital Ospedale Maggiore, Milan, Italy

Gynaecology & Obstetrics Intern, University Hospital Ospedale Maggiore, Milan, Italy

Internal Medicine Intern, University Hospital Ospedale Maggiore, Milan, Italy

General Surgery Intern, University Hospital Ospedale Maggiore, Milan, Italy

Pathology Intern, S. Paolo General Hospital, Milan, Italy

Accident & Emergency Intern, General Hospital of Melegnano, Milan, Italy

Education

Specialist in Thoracic Surgery, State University of Pavia, Pavia, Italy - Magna cum Laude

Specialist in General Emergency Surgery, State University of Milan, Milan, Italy - Magna cum Laude

Doctor of Medicine and Surgery, State University of Milan, Milan, Italy - Magna cum Laude

Licenses & Certifications

Member, Association of Physicians and Surgeons, Verona, Italy, 2017

Member, Association of Physicians and Surgeons, Province of Milan, Italy

Affiliations

Italian Society of Thoracic Surgery and Thoracic Endoscopy European Association for Cardio-Thoracic Surgery European Association of Thoracic Surgeons International Association for the Study of Lung Cancer – Member of the Staging and Prognostic Factors Committee- Thymic Domain and R-Factor Domain

Honors & Awards

Nominee, Research Paper of the Year, BMJ Awards, London, UK

Scholarship Recipient, National Cancer Institute of Milan

Recipient, Alfred Soffer Research Award, American College of Chest Physicians, Meeting, Orlando, FL USA

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