Andrei Surguchov, Ph.D.

Faculty member, Kansas University Medical Center,

Senior Medical Writer/Editor (part time) in Giddy, EasyEditing, Responsum Health

913-***-****, ady0oj@r.postjobfree.com; ady0oj@r.postjobfree.com

OBJECTIVE:

A challenging position of Assistant Editor for Neuroscience Communications which requires qualities of a technical leader and manager with excellent customer-focused leadership. The position is based on my experience in writing news articles of various lengths for different audiences, reviewing and editing of manuscripts, abstracts and posters in neuroscience.

SUMMARY OF QUALIFICATION:

Expertise in multiple areas of neuroscience. Experience in reviewing and editing scientific and medical texts in

· Ability to clearly articulate scientific and clinical data in written and verbal communication, knowledge of AMA writing style and GPPIII and

ICMJE guidelines. Experience with advanced writing features in MS Word.

· Reliable time management skills and ability to manage expectations and time schedule associated with responding to client needs.

· As a researcher and editor I perform literature searches and prepare summaries of literature

· Knowledge of GPP3 and ICMJE as well as other best practices relative to medical writers

Excellent team-working and oral and written communication skills as evidenced by:

oPreparing scientific data for publication: published ~75 review and research papers.

oPreparing and giving presentations in either oral or poster formats:

30 oral and poster presentations at a variety of scientific meetings.

Writing grant proposals for federal institutions and private foundations.

Analytical skills:

Analysis of complex scientific results both for laboratory experiments and published data.

Ability to clearly articulate scientific and clinical data in written and verbal communication. Experience with advanced writing

features in MS Word and other Microsoft Office software.

Editing and reviewing manuscripts for a peer-reviewed journals.

Working in a goal-oriented collaborative environment.

EDITOR, REVIEWER:

Certificate of Outstanding reviewer in Tissue and Cell, Archives of Biochemistry and Biophysics, 2017, 2018. Certificate of Recognized reviewer in Tissue and Cell, Archives of Biochemistry and Biophysics, Experimental Eye Research, Molecular and Cellular Neuroscience, Neuroscience

Letters, FASEB, and other journals.

KEY RESEARCH CONTRIBUTIONS:

2001- 2016 - Research biologist and Medical writer VA Medical Center, Kansas City, MO

2021 – Aug 2022 – Research Analyst, Hughes Hubbard &Reed LLP.

Writing experience:

Wrote and edited 70 manuscript for high ranking biomedical journals, all of them were published.

Associate Professor - 1998 - 2001 Washington University, St. Louis, MO

Performed structure-function studies of synuclein’s role in health and human diseases. Studied matrix metalloproteinase 9 (MMP-9) in neurodegenerative diseases and cancer.

Senior Investigator 1995-1998 University of Utah, UT

Identified a new retinal protein synoretin (g-synuclein) and investigated its role in health and diseases.

Published two research papers and made 3 oral/poster presentation at ARVO meetings

Assistant Professor,

1992-1995 Baylor College of Medicine, Houston, TX

Investigated genetic control of lipid metabolism and role of apolipoproteins in cardio-vascular diseases

Established a correlation between polymorphism in apolipoprotein III promoter region and predisposition to hyperlipoproteinemia

Found a role of apolipoprotein E (apo-E) in polymorphisms in coding region and the development of atherosclerosis and hyperlipoproteinemia.

Published five articles in scientific journals.

EDUCATION:

Ph.D. Biochemistry and Molecular Biology, Moscow University, Russia

M.S. Biochemistry, Moscow University, Russia

B.S. Biochemistry, Moscow University, Moscow, Russia

PROFESSIONAL ACTIVITIES:

Society for Neuroscience, 2010 - 2019current

Association for Research of Vision and Ophthalmology (ARVO) 1999 -2012

Invited reviewer for peer review journals 2012- current

Chief Editor – Biochemistry Research International; Member of Editorial Board in Frontiers in Molecular Neuroscience, Cell Biochemistry and other 10 Scientific Journals, 2014- current

SELECTED PEER-REVIEWED PUBLICATIONS:

Chapters in the books.

1 A. Surguchov. Molecular and cellular biology of synucleins. International Review of Cell and

Molecular Biology, 270, 225-317, 2008.

2 A. Surguchov. Intracellular dynamics of synucleins: Here, there and everywhere. International

Review of Cell and Molecular Biology, 2015, 320:103-169.

3 Surguchov A. in “Protein Aggregation” (Editor: DA Stein). Folding and unfolding of synucleins,

Nova Science Publishers, 2011

4 Surguchov A.” Advances in Brain Research” (Eds: OB. Williams, GI Wilson). “Two Faced

Members of the Family: The Synucleins”, 2012.

5 Surguchov A. Academic Editor. “Synucleins: Biochemistry and role in diseases”, 2018.

IntechOpen.

6 Surguchov A. Reviewer of the book "Frontiers in Clinical Drug Research - Alzheimer Disorders”.

Bentham Science Publishers. 2018.

7 Emamzadeh FN and Surguchov A. Parkinson’s disease. In: ”Predictive imagable biomarkers for

brain disorders”. June 2019, Front. Neurol. Eds: PK. Mandal, L Ersland, doi:

10.3389/fneur.2019.00583.

8 Surguchov A. Biomarkers in Parkinson’s disease. Chapter in a book: “Towards Translating

Biomarker Research of Neurodegenerative Diseases to Clinical Practice”, Neuromethods Series by

Springer Nature. Eds. P. Peplow, B. Martinez, TA Gennarelli. 2022, 173, pp. 155–180.

Articles in peer reviewed journals

Pronin AN, Morris AJ, Surguchov A, Benovic JL. Synucleins are a novel class of substrates for G

protein-coupled receptor kinases. J Biol Chem. 2000, 275, 265**-***** (>450 citations).

A. Surguchov, B. McMahon, E. Masliah, I. Surgucheva. Synucleins in ocular tissues. J Neurosci Res,

2001, 65, 68-77

A. Surguchov, RE. Palazzo, and I. Surgucheva. Gamma synucleins: subcellular localization in

neuronal cells and effect on signal transduction. Cell Motility and Cytoskeleton, 2001, 49, 218-228

Surgucheva I., McMahan B, F. Ahmed, Tomarev S, Wax MB, Surguchov A. 2002. Synucleins in

glaucoma. J Neurosci Res, 68: 97-106.

Surgucheva I, Sivak, JM, Fini ME, Palazzo RE and Surguchov A. Effect of g-synuclein expression on

matrix metalloproteinases. Arch Biochem Biophys. 2003, 410:167-176.

Maurage CA, Ruchoux MM, De Vos R, Surguchov A, Destee A. Retinal involvement in dementia with

Lewy bodies: A clue to hallucinations? Ann Neurol. 2003, 54 (4):542-7.

Snyder HM, Mensah K, Surgucheva I, Festoff B, Surguchov A, Wolozin B. β-Synuclein prevents

Proteasomal inhibition by α-synuclein but not g-synuclein. J Biol Chem, 2005. 4; 280:7562-9.

Surgucheva, B. Yue, BC Park, S Tomarev and A. Surguchov. Interaction of myocilin with g-synuclein

and its role in neurodegeneration in glaucoma. Cell Mol Neurobiol, 2005, 25, 6, 1009-33

Surgucheva I, Ninkina N, Buchman VL, Grasing K, A. Surguchov. Protein aggregation in retinal cells

and approaches to cell protection. Cellular Molecular Neurobiology, 2005, 25, 6, 1051-1066.

Surgucheva I, McMahon B., A. Surguchov. Dynamic intracellular localization of g-synuclein: a clue

to its functions. Cell Motility and Cytoskeleton, 2006, 63, 8, 447-458.

Surgucheva I, Surguchov A. 2008. g-Synuclein: Cell-Type Specific Promoter Activity and Binding to

Transcription Factors. J Mol Neuroscience, 2008; 35(3):267-71.

A. Surguchov. Molecular and cellular biology of synucleins. International Review of Cell and

Molecular Biology, 2008, 270, 225-317.

I Surgucheva, A Shnyra, J Goldberg, A. Weisman and A Surguchov. g-Synuclein as a marker of the

retinal ganglion cells, Molecular Vision, 2008, 14:1540-1548.

I Surgucheva, V Shestopalov and A Surguchov. Effect of g-synuclein silencing on apoptotic

pathways in retinal ganglion cells. J Biol Chem, 2008, 284 (52): 36377-85.

A. Surguchev and A. Surguchov. Conformational Diseases: Looking into the eyes. Brain Research

Bulletin, 2010, 81, 12-24

Surgucheva I, Chidambaram K, Willoughby DA, Surguchov A. MicroRNA regulates MMP-9

expression. J Ocular Biology, Diseases and Bioinformatics, 2010; 3: 41-52,

Surgucheva I, McMahon B, Surguchov A. Patterns of synuclein expression throughout lens

development. J Biophys Chem. 2010; 1: 12-18

Surgucheva I and Surguchov A. Expression of caveolins in trabecular meshwork cells and its

implication in pathogenesis of glaucoma. Molecular Vision 2011;17: 2878-2888

Surgucheva I, Sharov V; Surguchov, A. g-Synuclein: Seeding of α-Synuclein Aggregation and

Transmission Between Cells. Biochemistry, 2012; 51(23):4743-54

Surguchov A. Synucleins: are they two-edged swords? J Neurosci Res, 2013; 91 (2):161-6.

Surguchov A. Parkinson’s disease: Is there a light at the end of a tunnel? (Editorial). Advances in

Parkinson’s Disease, Nov 2013, 2, 3, 116-117.

Surgucheva I, Gunewardena S, Rao HS, Surguchov A. Cell-specific post-transcriptional regulation of

g-synuclein gene by micro-RNAs. PLOS One, Sep 2013, PONE-D-13-25172

Surguchov A. What do synucleins do in the nucleus? (Editorial). Journal of Genetics, Molecular and

Biology, 2014, 1, 1.

Surguchov A. SNCG (synuclein, gamma). Atlas Genet Cytogenet Oncol Haematol. June 2014. URL:

http://AtlasGeneticsOncology.org/Genes/SNCGID42343ch10q23.html

Surgucheva I, Newell KL, Burns J and Surguchov A. New α- and g-Synuclein Immunopathological

Lesions in Human Brain. Acta Neuropathologica Com, 2014, 2: 132.

Surgucheva I, He S, Sharma R, Rich M, Ninkina NN, Stahel P, Surguchov A. Role of synucleins in

traumatic brain injury. Mol Cell Neurosci. 2014, 63, 114–123.

Surguchev A, Surguchov A. Effect of a-synuclein on membrane permeability and synaptic

transmission: a clue to neurodegeneration? J Neurochemistry, 2015; 132 (6): 619-21

Surguchov A. Intracellular dynamics of synucleins: Here, there and everywhere. International Review

of Cell Molecular Biology, 2015; 320:103-169.

Surguchov A. Atlas of Genetics and Cytogenetics in Oncology and Hematology, 2015, 19, 210-217.

Surguchov A. Parkinson’s disease: early diagnosis and association with melanoma. Brain Sci. 2016,

6(2), 17; doi: 10.3390/brainsci6020017.

Surguchov A. g-Synuclein as a cancer biomarker: viewpoint and new approaches. Oncomedicine,

2016, 1:1-3. doi:10.7150/oncm.16748.

Surguchov A. Type-2 diabetes and Parkinson’s disease: a cross-talk between main players. Journal

of Diabetes Mellitus and Metabolic Syndrome, 2016, 1, 1-7.

Surguchov A, Singh V, Surgucheva I, Sharma M, Singh V. New putative epigenetic mechanism of

epilepsy. Frontiers in Neurology, 2017, 8:3. doi: 10.3389/fneur.2017.00003.

Surguchev AA and Surguchov A. Synucleins and gene expression: ramblers in a crowd or cops

regulating traffic? Front. Mol. Neurosci. July 2017, 10, 1-7 224 doi: 10.3389/fnmol.2017.00224

Surguchov A. α-Synuclein Interacts with Lipoproteins in Plasma. Frontiers in Molecular

Neuroscience, 2017, Nov 2, 2017. doi: 10.1007/s12031-017-0967-0.

Emamzadeh FN and Surguchov A. Parkinson’s disease: Biomarkers, Treatment, and Risk Factors .

Frontiers in Neuroscience, Neurodegeneration, 12, 61230, August 2018

https://doi.org/10.3389/fnins.2018.00612

Surguchov A. Academic Editor of a Book: “Synucleins: Biochemistry and role in diseases”, 2018.

IntechOpen.

Surguchov A. Protein-DNA interaction: one step closer to understanding the mechanism of

neurodegeneration. October 2018, J Neurosci Res., DOI: 10.1002/jnr.24346.

Surguchov A. Reviewer of the book chapter "Frontiers in Clinical Drug Research - Alzheimer

Disorders”. Bentham Science Publishers. 2018.

Surguchev AA, Surguchov A. Integrins-A missing link in synuclein's pathogenic mechanism.

J Neurosci Res. 2019 Jan 16. doi: 10.1002/jnr.24384. PMID: 30648275

Surguchev AA, Emamzadeh FN, Surguchov A. Cell responses to extracellular a-synuclein.

Molecules 2019, 24(2), 305; https://doi.org/10.3390/molecules24020305.

Mojbafan M, Tina S, Zafarghandi Motlagh F, Surguchov A, Nilipour Y, Zeinali S. Genetic variability in

Iranian limb-girdle muscular dystrophy type 2B patients: An evidence of a founder effect. Mol Genet

Genomic Med. 2019 Dec;7(12):e1029. doi: 10.1002/mgg3.1029

Surguchov A, Emamzadeh FN, Surguchov AA. Amyloidosis and longevity: a lesson from plants.

Biology, 2019, 8(2), 43; https://doi.org/10.3390/biology8020043

Emamzadeh FN and Surguchov A. Parkinson’s disease. In: ”Predictive imagable biomarkers for

brain disorders”. June 2019, Front. Neurol. Eds: PK. Mandal, and L Ersland.

Surguchov A. “Little pigeons can carry great messages” in a book: “Synucleins: Biochemistry and

role in diseases”, IntechOpen, 2019.

Surguchov A. Invertebrate Models Untangle the Mechanism of Neurodegeneration in Parkinson's

Disease. Cells. 2021 Feb 16;10(2):407. doi: 10.3390/cells10020407

Surguchov A. Caveolin: a new link between diabetes and Alzheimer’s disease. Cell Mol

Neurobiology, 2020 Jan 23. doi: 10.1007/s10571-020-00796-4

Surguchev AA, Surguchov A. A member of the ABC transporter family in healthy and ailing brain.

(Editorial) Brain Sciences, February 2020, 10, 121; doi:10.3390/brainsci10020121

Surguchov A. Analysis of protein conformational strains – a key for new diagnostic methods.

International Journal of Molecular Science, 2020, 21, 2801; doi:10.3390/ijms21082801

Surguchov A. When pandemic meets epidemic: COVID-19 and neurodegenerative diseases

(Editorial) Biochemistry Research International, 2020

Surguchov A, Barnel L, Surguchev AA. Phytochemicals as regulators of genes involved in

synucleinopathies. Biomolecules, 2021, 11 (5), 624

Surguchov A ”Biomarkers in Parkinson’s Disease”. Chapter in a book Peplow PV et al., eds. Neurodegenerative

Diseases Biomarkers. 2022. Neuromethods, vol 173. pp 155-180. Humana, New York, NY.

https://link.springer.com/protocol/10.1007/978-1-0716-1712-0_7

Surguchov A., Surguchev AA. Synucleins: new data on misfolding, aggregation and role in diseases.

Biomedicines, 2022;10 (12):3241. doi: 10.3390/biomedicines10123241.

Surguchov A. alpha-Synuclein and mechanisms of epigenetic regulation. Brain Sciences, 2023, 13, 150.

https://doi.org/10.3390/

Surguchov A, Emamzadeh FN, Titova M, Surguchev A. Controversial properties of amyloidogenic proteins and

peptides: new data in the COVID era. Biomedicines 2023, 10, 11(4):1215. DOI: 10.3390/biomedicines11041215

Scopus: https://www.scopus.com/authid/detail.uri?authorId=700-***-****

Website: http://genetics1972.org/Andrei/

Linkedin: https://www.linkedin.com/in/andre-surguchov-a5231713

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