CURRICULUM VITA nd

SURNAME: Luka-Danis

OTHER NAMES: Augustine

(Formerly Augustine Nsa Ani )

DATE/PLACE OF BIRTH 25th February, 1942; Calabar

STATE OF ORIGIN Cross River

LANGUAGES SPOKEN English, Yoruba, Efik

PRIMARY SCHOOL EDUCATION Sacred Heart School, Calabar 1946 – 1948 Holy Cross School, Lagos 1949 – 1954

COLLEGE EDUCATION King’s College, Lagos 1955 – 1961 West African School Certificate 1959

GRADE 1

Higher School Certificate 1961

Army Proficiency Certificate

(King’s College Cadet Unit) Part I 1958

Part II 1959

UNIVERSITY EDUCATION

University of Ibadan, Ibadan 1962 – 1967

University of Rochester, Rochester, New York 1970 – 1972 The Royal College of Surgeons, Edinburgh 1972 – 1973 GRADUATE ACADEMIC QUALIFICATION MB, BS (Ibadan), July 1967 ECFMG (USA) 1969 – (Equivalent of M.D.)

HIGHER POST-GRADUATE QUALIFICATION Fellow of the Royal College of Surgeons

(Edinburgh) 1973

HIGHER POST-GRADUATE AWARDS

AND CERTIFICATION Fellow of the International Academy of Proctology 1982.

“in recognition of high professional

Qualification and having met the requirements

In the specialty of Coloproctology…”

Fellow of the International College

of Surgeons 1984

“in recognition of distinguished professional

achievements and broad specialization in

general, Colon and Rectal Surgery…”

Certificate in Colonoscopy, 1989

Kendrick Memorial Hospital

Moresville, Indiana, U.S.A.

SCHOLARSHIPS, TRAINING

AWARDS, REASERCH GRANTS Federal Government Scholarship

(University of Ibadan) 1962 – 1967

Rochester post-graduate Training/Fellowship

(University of Rochester, Rochester,

New York) 1970

Principal Registration Status

(British Medical Council) 1973

U.I. Senate Research Grant 1975

National Science and Technology

Development Agency (N.S.T.D.A.)

Research Grant Award 1977

MARITAL STATUS Married with four children and

Two grandsons

CONTACT ADDRESS E-mail: adxhlp@r.postjobfree.com

TELEPHONE 080********

PROFESSIONAL AND ACADEMIC EXPERIENCE:

July 1967 to June 1968: House Officer, Surgery & Medicine, Lagos University Teaching Hospital,

Lagos.

July 1968 to July 1969: Senior House Officer, Surgery, Lagos University Teaching Hospital,

Lagos.

August 1969 to June 1970: Registrar, Surgery,

Lagos University Teaching Hospital,

Lagos.

Special National Duty Positions

Brigade Medical Officer

(17th Brigade, Nigeria Army)

Nov. 1967 to May 1968

Rank: Field Captain

3 Field Ambulance, Port Harcourt,

Medical Reception Centre, Bori.

Senior Medical Officer (Surgery),

October 1969 to February, 1970

Rank: Field Major

Military Hospital, Yaba

Army Rehabilitation Centre, Oshodi.

July 1970 to June 1972: Associate Resident/Fellow (Surgery) Resident/Fellow (Surgery)

Strong Memorial Hospital and University

of

Rochester, New York, 14642.

Rotational Service in General Surgery;

Vascular Surgery: Orthopaedic Surgery;

Urology; E.N.T; Thoracic Cardiovascular

Surgery; Colorectal Surgery, Clinical

Teaching

And Demonstration to Medical Students.

Laboratory Processing in Surgical

Anatomy.

Clinical Pathology.

Chairman of Surgery: Prof. C. G. Rob

October 1972 to January 1973: Senior Clinical Attachment, Western Infirmary,

Glasgrow. Scotland General Surgery and

Gastro-Enterology, Consultants: Professor

Williams Kay, Mr. Douglas Clarke

Registrar,

Ayr County Hospital

Ayr, Scotland.

January 1973 Fellow of the Royal College of Surgeons

(Edinburgh)

February 1973 to September 1973 Post Fellowship Registrar in Surgery,

(Principal Registration Status-British

Medical Council)

St. Georges Hospital, London SWI

Mr. James Guillespie

Lord Rodney Smith

St. Stephen’s Hospital,

London W1.

Mr. C. A. Philips

Royal Northern Hospital,

London N7,

Mr. Adrian Matson

Vascular Surgery, General Surgery,

Emergency

Surgery. (With access to full operating

room

Facilities as with Principal Registration

Status)

September 1973 to November 1973: Senior Registrar, Department of Surgery, UCH

Ibadan

Head of Surgical Resident Staff. Surgical

Services

In General and Gastroenterology, Urology,

Gastroscopy, Colon and Rectal Surgery,

Emergency

And accident Surgery.

Design of Surgical Research Work in

Venous

Thrombosis.

Acting Consultant Surgeon (June 1975):

took active part in the teaching of Medical

Students.

Special position:

Acting Consulting Surgeons,

Westley Guild Hospital, Ilesha

(January to April 1975)

April 1976 to December 1978: Consultant Surgeon, UCH, Ibadan Lecturer in Surgery, Examiner in Surgery

University of Ibadan, Ibadan.

Main Specialization: General Surgery,

Thyroidectomy: abdominal surgery –

Gastro

Esophageal surgery for achalasias

Strictures and

Cancer, modalities of Surgical repair for

peptic

Ulcer; Bilary Surgery: pancreatic surgery:

Surgery of the small intestine, colorectal

surgery;

cancer surgery and chemptherapy.

Special interest: Colon and rectal Surgery,

Haemorrhoids, fistulas, and Fissures

(Proctology)

Teaching of medical students in clinical

surgery.

Among the students I taught during this

period are

Dr. (Mrs.) Oduwole (S. S. A. to the Vice

President)

Prof. Adewole (former minister of health)

Training of Surgical Residents in basis

skills,

Technique and knowledge of Surgery.

(The department had no research students for

supervision)

Special Research Interest; Fistula-in-ano:

Fistulagrams. Field studies in Ibadan,

Oghomosho and environs on incidence of

various anal infections e.g. fistulas,

fissure-in-ame

haemorrhoids. Venuos Thrombosis,

clinical

incidence Post operatively, Radioactive

iodine Scanning, venograms.

Head of Surgery: Prof. A. Adeloye

FURTHER SURGICAL

TRAINING AND EXPERIENCE International Academy of Proctology: Kendrick Mechanical Hospital,

Mooresville, Indiana

Nov. – Dec. 1986; June – August, 1989,

Colonoscopy and proctology; laser

Surgery. Hands-on training.

Instructor: Dr. Williams M. Kendrick, M. D

Certificate in colonoscopy; hands-on

Colonoscopy training, excision and biopsy of

Colonic polyps, use of diathermy, snare and

laser beam in colonoscopy for treatment of

colonic polyps and affections.

Photocoagulation, banding, laser surgery in the

treatment of internal haemorrboids,

Condylomata, etc. excision of colonic polyps.

Disagnosis and management of Chron’s

Disease, ulcerative colitis. Diverticular disease, colon cancer, etc.

RESEARCH fistulographic studies of anal fistulas and Influence on surgical management

5-years study – UCH, Ibadan

Retrospective clinical review,

Prospective clinical study; fistulography as

Adjunct: Field study in Ibadan, Idi-ayunre,

Ogbomosho, Radiological classification of

anal fistulae. (Research was part supported by U.I Senate Research Grant)

Natural history of deen vein Thrombosis in Nigeria Patients (Supported by funds from

National Science and Technological

Development Agency) N.S.T.D.A

Could not complete this study because

Of resignation in 1978

OTHER APPOINTMENTS: Medical Director and Consultant January 1979 to 1989 Surgeon, Blue Shield Hospital, Onike-Yaba Consultant Surgeon

St. Nicholas Hospital, Lagos

Organization and administration-

Bi-weekly clinical meetings, training of junior

Doctors for preliminary National Post-graduate

Specialty Board Examinations.

1984 to 1989: Medical Representative of S.O.S.,

Geneva in Nigeria

Emergency management and admission of sick

or injured expatriates preparatory to

transportation overseas by S.O.S. Air

ambulance.

1990 – 2009 Consultant Surgeon

Providence Hospital

Lagos.

2010 – 2012 Chief Consultant Surgeon

Coordinator of Endoscopic and

Laparoscopic procedures

Lagos state University Teaching Hospital

Associate Lecturer in Surgery

Examiner in Surgery

Lagos State University College of Medicine

Ikeja.

Head of General Surgery II Unit, consisting

of an Associate Professor of Surgery (sabbatical), a lecturer in Surgery, a Senior Registrar, Surgical Residence and two House officers.

Initiated the weekly 8-9am pre-ward round

Complications teaching round. Initiated the weekly Joint Unit/Radiology conference which is still

in existence.

Trained and supervised surgical residence.

I was largely responsible for the setting up of

Endoscopic and Laparoscopic procedures in the

Hospital. Gave lectures and clinical teaching to

the medical students and was also an Examiner

in Surgery.

Kelu Specialist Hospial, Victoria Island

2013 – till date Practising Consultant Surgeon & Colonic Endoscopist.

Private Research into Systemic

Inflammatory Response Syndrome

(working into consult with the intensive

care unit of Savannah Hospital,

Surulere)

Presented outcome of research entitled

“treatment of Lassa fever and the covid-

19” to the Federal government and the

Lagos state government through the

Office of transformation Creativity and

Innovation of the Lagos State. (2020)

see attached Appendixes 1 & 2.

PUBLIC SERVICE APPOINTMENT:

1990 -1994 Member, National Orthopaedic Hospitals

Management Board (N.O.H.M.B),

Chairman, Panel of Enquiry into the

Affairs of the Administration of the National

Orthopaedic Hospital, Kano

1994. Reports formed the basis of subsequent

overhaul and rehabilitation of the Hospital.

PUBLISHED SCIENTIFIC WORK: (1) Dermatofibrosarcoma Protruberans of the Patid Gland; Case Report: T. A.

Junaid, A. N. Ani, B. Ejeckam. Br. J.

Oral Surg 12(3) 298-301 January 1975

(2) Fistula-in-ano: Review of 82 cases

A. N. Ani, T.F. Solanke. Dis Colon

January-February, 1976

(3) Gastro collie Fistula: Case Report:

A. N. Ani, F. T. Solanke, Gh Med J.1974.

(4) Simultaneous rapture of the spleen

And Board Ligament in a pregnant

Female: O. Ogunbode, A. N. Ani

Adegboye A. A., Int. Surg. 62(20):

534-5, October 1976

(5) Dematofibrosacoma Protruberans;

Analysis of 6 cases in an African

Population: A. N. Ani, E. B. Attah,

42:934-40, December, 1976.

(6) Decay of Methyl-green-pyrinophillia

In Burkitts Lymphoma: E. A. Attah

A.N Ani, A. Odoh, Acta Cyctologia

21:151,1977, This paper has been

Published by “Current Literature of

Blood” 1977.

(7) Carotid body tumour and allied

Tumours (chemodectomas) A. N. Ani,

T. A Junaid F. D. martinson, A. Adeloye,

Int. Surg. 1079 May-July;

64(4) 43-48 (23 ref)

(8) Radiological evaluation of anal

Fistulae a prospective study of

Fistulograms: A. N. Ani and S. B.

Lagundoye Clin radio 1979 30, 21-24

(9) Anorectal disease in Western Nigeria

Adults: A field survey: A. N. Ani

Dis Col & Rect

June 1983 Vol 26, No. 6 381-385

(10) Intestal Perforation in an adult: A. N

Ani, Itayemi S. J. R. Coll Surg.

Edinb. 1982 May: 27(3) 186-7

(11) Radiological Classification of Anal Fistulae: A N Ani, Am J Proct Gastroenterol No 10; 28-32,

1983.

INTERNATIONAL CONFERENCES: West African Association of Radiologist Conference, Lagos June 1978 (paper present)

West African Assoication of Gastro-

Enterologist Conference, Ibadan

October 1978 (paper presented)

35th Congress of International Academy

Of Proctologist, Athens, March 1982

(Paper work presented)

36th Congress of International Academy

Of Proctologist, Benin, China – September

1983.

36th Congress of International Academy

Of Proctologist, Honoluju, Hawaii, March

1985

133th Congress of International College

Of Surgeons, Madrid-May 1968 (paperwork)

134th Congress of International College

Of Surgeons, Milan-May 19868 (paperwork)

6th Congress of International College

Of Surgeons, (Nigerian Chapter), May

1989.

West African College

Of Surgeons, March 1990

8th Congress of International College

Of Surgeons, Lagos, March 1993.

Scientific Meeting of Association of Academic

Surgeons (Nigerian Chapter) July 2011

Scientific Sessions and Annual General

Meeting of the Association of Resident Doctors

(LASUTH) September 2011 (chaired the opening

Session and declared the ARD Library open)

Member, Society of American Gastro-intestinal

Endoscopic Surgeons (2014)

CURRENTLY

Currently, I am a practicing consultant surgeon in Lagos with research and study interest in Systemic Inflammatory Response Syndrome (S.I.R.S). This condition is usually encountered in surgical cases and emergencies such as; ruptured appendicitis or perforated typhoid enteritis which results in peritonitis. The resultant bacterial sepsis is very profound, with high mobility and mortality rate, because of the component endotoxin released by the respective bacterial involved. Other conditions that fully exhibits S.I.R.S. include organ injuries such as haemorrhagic pancreatitis, bacterial hepatitis, multiple trauma and injuries, extensive (70-90%) burns. All these conditions carried about 30-50% mortality rate. Extensive burns (80- 90%) rarely survive.

I have in the cause of this research which date back to 2012, been able to link Ebola fever with S.I.R.S (2015). Studies carried out subsequently by researchers in Holland came to a similar conclusion and today we have what is generally recognized as viral

“sepsis”, being associated with mutant microbes such as Ebola, SARS, Middle-East respiratory syndrome, Laser fever, and corona virus. I have since been able to identify a formulation of drugs substances that would almost instantaneously reveres SIRS and put the patient in the mode of resolution and healing with optimal endogenous immune response capacity. This would directly translate into the cure for COVID-19 and this knowledge has been registered with the Nigerian Intellectual Property Rights. They has been no known cure for SIRS in history we are currently learning, along with our colleague abroad to carry out a clinical trial for the treatment of COVID-19 in the state of California USA, subject to availability of funding. SUMMARY OF KEY SKILLS

General Surgery

Colorectal Surgery

Thyroidectomy and Pancreatectomy

Colonoscopy

Research and Clinical Trials

Treatment and CURE of Cytokine Storm (in all its clinical presentations) – including Covid-19.

Cytokine Storm is also the main cause of high morbidity and mortality rates

(mortality rates of 30-50%) in Bacterial Sepsis with or without shock, Endotoxeamia and Endotoxic shock, Haemorrhagic panceatitis with or without necrosis, Hepatitis with or without abscess, Multiple injuries, aaaaextensive and multi-procedural surgery, and Extensive (70-95%) burns. All these account for a combined total mortality in excess of 20million annually, globally. Successful treatment of Cytokine Storm will bring the morbidity and mortality rates in these entities down close to zero.

APPENDIX 1

Dr A. Luka-Daniels FRCS(Ed), FICS, FIAP.

TREATMENT OF LASSA FEVER AND CORONAVIRUS (COVID-19) The novel coronavirus 2019-nCov

1

, which is responsible for severe respiratory illness, is on the upward rise with over 317,309 confirmed cases and 13,643 deaths in 188 countries and territories as of March 22, 2020. This raises an urgent need for an effective treatment of the deadly disease; however, current antiviral drugs have limited effects on 2019-nCov (SARS-CoV-2). The evidence from patient samples suggests that 2019-nCov (SARS-CoV-2) is actively acquiring new mutations that may enable it to escape antiviral drugs. This raises a serious challenge to the development of conventional drugs and of vaccines. The same limitations apply to other deadly RNA viruses such as SARS or MERS. Vaccines are most suitable for healthy individuals where active immunization is administered to boost the body’s defense against future invasion of the specific organism. Such immunization will do very little to a sick patient with acute infection and malnutrition because of a depleted immune response capacity. Passive immunization (antibody sera) given to the sick person is generally too transient to have any significant lasting effect. This is amply borne out by the experimental vaccines used in Congo Republic, during the recent outbreak of Ebola virus infection. REGN-EB3 and Ab-114 (both monoclonal antibodies harvested from survivals of Ebola infection) recorded mortality rate of 29% and 34% respectively. To this, Mike Ryan, Head of WHO Emergency Program, commented: “Trial’s positive findings were encouraging, but not enough on their own to bring the epidemic to an end.” Moreover, a new vaccine takes about a year to prepare. Ebola, Lassa fever, Severe Acute Respiratory Syndrome (SARS) and Coronavirus (COVID-19) all have one crucial clinical expression in common - Systemic Inflammatory Response Syndrome (SIRS). SIRS is a generalized inflammatory process in which the patient is very ill with profoundly debilitating effects and widespread tissue injuries and damages, progressing rapidly to organ failure (Multiple Organ Dysfunctional Syndrome (MODS)). Once MODS is established in an advanced stage, the clinical progression is irreversible, and death is inevitable. As a result of SIRS, there is gross depletion of immune response.

SIRS is responsible for the profound morbidity and high mortality rate associated with these viral cases. To date, there has been no known treatment or cure for SIRS. 1

named as SARS-CoV-2 by ICTV Coronaviridae Study Group on February 12, 2020 The author of the proposed treatment regime is the first person to directly link Ebola virus infection to SIRS (2015), (described subsequently in publication by other researchers as viral sepsis, with characteristics similar to bacterial sepsis) and has since identified the prescription for treatment and cure of SIRS. The treatment has been applied to several cases of surgery-related SIRS with dramatic and predictable response and success. Both items of knowledge have since been registered with Nigerian Intellectual Property Rights.

TREATMENT is specifically directed at complete cure of SIRS and the reversal of early organ failures, where they occur. This simultaneously allows complete restoration of all components of sustained endogenous immune response that will enable patients to destroy the virus and overcome infection. All this can be accomplished within a total of 48-72 hours of treatment after which the treatment is tailed off. The prescribed formulation consists of drug substances that are currently in clinical use and have no side-effects or complications.

With exception of those who present with irreversible organ failures, a total 100% cure rate is envisaged, and patients should test negative within one week. It will be the first time that SIRS is being treated and cured in history. In all these cases, it is very important to understand and appreciate what has brought about a state of grossly depleted immune response capacity.

A full complement of endogenous immune response is absolutely vital and must be restored immediately. It is our experience with cases of bacterial sepsis (septicemia), that where the correct and specific antibiotic is administered, patients still go into septic shock and mortality if immune response is depleted.

In these viral infections, an optimal immune response is required, not only to destroy the virus, but also to initiate and conclude resolution and healing.

On COVID-19 infection, additional and supportive treatment include the use of respirator equipment to assist respiration and correct hypoxaemia, and intravenous fluid to correct dehydration, both of which are compounding stimuli that contribute to organ failure. Should there be any secondary bacterial pneumonia, antibiotics can be administered.

Patients would have been investigated on admission (these include: full blood counts, electrolytes, urea, creatinine, blood sugar, etc.) for anemia, diabetes, ureania, and urinal problems, in order to modify the formulation and modality of treatment of SIRS accordingly. In conclusion, the treatment of these viral cases is entirely an aggressive clinical management centered on achieving an optimal endogenous immune response capacity. Complete cure and elimination of SIRS is key to rapid recovery and zero mortality.

Yours Sincerely, Dr. A. Luka-

Daniels

MB, BS., FRCS (Ed.), FICS, FIAP.

Formerly Chief Consultant Surgeon

Coordinator of Endoscopic and Laparoscopic Procedures, LASUTH, Ikeja.

Email: adxhlp@r.postjobfree.com Mobile:

+234 703-***-****

APPENDIX 2

Contact this candidate