Research Associate Senior Scientist

PRADEEP V

Mobile: +91-979*******/+91-866******* Email: *******.***@*****.***

LinkedIn: linkedin.com/in/pradeep-venkatesan

PROFILE SUMMARY

Experienced toxicology professional with 6+ years of industry experience in research, product development, publication, and project management

Proficient in in vivo toxicology and safety pharmacology testing, data analysis, and report writing

Expertise in acute and chronic systemic toxicity, respiratory safety, carcinogenicity, and biocompatibility testing of pharmaceuticals, agrochemicals and medical devices

Skilled in statistical analysis using GraphPad Prism and experience in using various other software tools

Knowledge of regulatory guidelines such as OECD-GLP, ISO17025, AAALAC, ICH, OCSPP and CPCSEA

Strong communication and interpersonal skills, with the ability to collaborate effectively with internal and external teams

Demonstrated ability to meet project deadlines and commitments, with a proactive and results-driven approach

Proficient in animal handling and surgical procedures, such as dissection of rats, mice, and rabbits for experimentation

Experience in designing and executing toxicology and safety pharmacology studies, and working in compliance with OECD-GLP, ISO17025, AAALAC, ICA, OCSPP and CPCSEA guidelines

AREAS OF EXPERTISE

Toxicological risk assessment

Medical writing

Technical report writing

Safety assessment

Regulatory compliance

Experimental design and data analysis

Animal welfare regulations

Biostatistics

Quality control and assurance

Good laboratory practices (GLP)

Excel Spreadsheet validation

Team management and leadership

Scientific writing and editing

Research & development skills

Stakeholder engagement

Study design and protocol development

Wholebody Plethysmography

Communication skills

Inhalation

Pharmacokinetics

Interpersonal and leadership skills

Respiartory safety studies

pharmacodynamics

ACADEMICS & ACCREDITATION

Bachelor of Technology in Biotechnology from Jeppiaar Engineering College, India – 2016

CURRENT EMPLOYMENT

Dec 2022 - Till Date Anthem Biosciences Private Limited, India

Senior Scientist - Toxicology

Design, plan, and execute in vivo toxicological and pharmacological safety studies

Analyze and interpret toxicological and pharmacological safety study results

Conduct Central Nervous Safety and Respiratory Safety Pharmacology Studies according to ICH Guideline

Perform acute 6 pack toxicity studies on various pharmaceutical and agrochemicals using mice, rat, and rabbits

Conduct Repeated Dose Toxicity studies on rats and rabbits according to OECD and New Drugs and Clinical Trail Rules Guidelines

Prepare toxicological study plans and reports

Handle and conduct inhalation studies using Nose only inhalation chambers (CH and EMMS)

Ensure compliance with OECD-GLP, ISO 17025, AAALAC, and CPCSEA guidelines

Preparation of SOP

Oct 2018 – Dec 2022 Bioneeds India Private Ltd, India

Associate Scientist - Toxicology

Currently designing, planning, and executing in vivo toxicological and biocompatibility studies on various classes of medical devices through different routes of administration such as systemic toxicity, skin sensitization, intracutaneous dermal irritation, penile, vaginal, and mucous irritation

Currently conducting acute 6 pack toxicity studies of various pharmaceuticals and agrochemicals in mice, rats, and rabbits, and chronic vapor generator study in rats

Preparing extracts in accordance with ISO 10993 - Part 12 and toxicological study reports

Interpreting toxicological and biocompatibility study results and ensuring compliance with OECD-GLP, ISO17025, AAALAC, EPA-OCSPP, and CPCSEA guidelines

Apr 2018 – Oct 2018 Liveon Biolabs Pvt Ltd, India

Research Associate - Toxicology

Designed, planned, and executed in vivo toxicological and biocompatibility studies

Conducted acute & chronic systemic toxicity studies on various pharmaceuticals, agrochemicals, medical devices in mice, rats, and rabbits

Skilled in statistical analysis using GraphPad Prism software

Proficient in analyzing and interpreting study results and reviewing reports

Oct 2016 – Jan 2018 Centre for Toxicology and Developmental Research, SRU, India

Junior Research Associate - Toxicology

Performed acute and chronic toxicity evaluations on a variety of pharmaceutical and agrochemical substances in animal models including mice, rats, and rabbits.

Carried out pharmacological and toxicological development studies to assess the safety and efficacy of drugs

Conducted experiments using animal models such as the carrageenan-induced inflammatory model and the high-fat diet-induced diabetes mice model to investigate the effectiveness of potential treatments

Conducted ocular kinetics studies in rabbits to assess the movement and absorption of drugs within the eye

Proficient in dissection of rats, mice, and rabbits for experimentation

Experienced in administering substances via various routes and in handling laboratory animals such as rabbits, rats, mice, and guinea pigs

Conducted behavioural assays of rodents using various maze models, including elevated plus maze, open field test, grip strength, and infrared actimeter

Skilled in analyzing behavioural data to evaluate the efficacy of potential treatments or interventions

PROJECTS HANDLED

Acute systemic toxicity study in mice Study director ISO 10993 - Part 11 and USP 88

Skin sensitization study in guinea pig Study director ISO 10993 - Part 10

Intracutaneous reactivity test and dermal skin reaction in rabbits Study director ISO 10993 - Part 10 and USP 88

Eye irritation test in rabbits Study director ISO 10993 - Part 10

Penile and vaginal irritation study in rabbits Study director ISO 10993 - Part 10

Acute oral and dermal toxicity study in rats Study director OECD 423, 420 and 402

Acute Skin and Eye irritation/corrosion study in rabbit Study director OECD 404 and 405

Skin sensitization study in guinea pig Study director OECD 406

Acute inhalation toxicity study in rats Study personnel OECD 403

28 days and 90 days oral toxicity studies in rat Study personnel OECD 407 and 408

28 days and 90 days dermal toxicity studies in rat Study personnel OECD 410 and 411

Respiratory safety studies in rat using wholebody plethysmography

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