SAMUEL CORWIN BIELIGK, MD, FACS

Professional Address:

Mid-Atlantic Surgical Oncology, LLC

**** *. ****** ******

Tulsa, Oklahoma 74136

Contacts:

918-***-**** (home)

443-***-**** (cell)

email: adw3vg@r.postjobfree.com

Board Certification

Diplomate of the American Board of Surgery; May 10, 1994 (Certificate # 39308) MOC recently verified through Dec 2024

10-year re-certification; Oct 17, 2003; 20-year re-certification; Dec 14, 2014 (exp 2024) Board Eligible - Complex General Surgical Oncology - SSO Fellowship 1997 (2015- board created)

BLS/ACLS Certified: 1/22/2020 - ecard code #206********* ATLS Certified: Provider re-certification June 24-25, 2020 New Orleans. La Exp 2024 Licensure

11/3/2011 Oklahoma License#28750 Exp. Date –11/1/2024 4/10/2008 Missouri License#200-***-**** Exp Date - 1/31/2024 6/5/2001 Maryland License# D0057659 Exp. Date – 9/30/2024 4/4/1998 Texas License # K4862 Exp. Date – 8/31/2024 1995 New York License# 199416 Exp. Date – 9/30/2008 (Inactive) 2/6/1989 Louisiana License# 020222 Exp. Date – 10/31/2024 Staff/Faculty Appointments

2022-presentWeatherby Healthcare, Inc Locums General Surgery - Mercy Hospital Ardmore and Union Hospital Elkton Maryland (Christianacare) 2020-2022 Staff Surgeon/Surgical Oncologist – Missouri Delta Medical Center Sikeston, Missouri Developed and worked with St. Francis (Cape Girardeau Oncology team) including participation in multi disciplinary conference attendance to develop neoadjuvant treatment for Breast Cancer patients (not been done before at MDMC) Med Onc contact Michael Naughton, MD

2017-2020 Attending Surgical Oncologist/General Surgeon Tahlequah City Hospital, Tahlequah Oklahoma developed Rural/Native multi disciplinary treatment of complex malignancy including breast in conjunction with medical and radiation oncology Vicki Baker, MD and Fred Willison, MD

2015-2017 Attending Surgical Oncologist/General Surgeon, Warren Clinic & Saint Francis Hospital Cancer Liaison Physician

2011- 15 Attending Surgical Oncologist, Cancer Treatment Centers of America-SRMC Tulsa, Oklahoma

Clinical Assistant Professor of Surgery University of Oklahoma, Tulsa 2008-11 Attending Surgeon, Director of Surgical Oncology and Chairman of Cancer Committee

Mercy Medical Center, Joplin Missouri (Developed and maintained Multi disciplinary Breast management in conjunction with medical and radiation oncology) 2004-8 Assistant Professor, Department of Surgery, Division of Surgical Oncology University of Maryland Medical School, Baltimore, Md Director, Surgical Oncology Baltimore Washington Medical Center 2002-8 Attending Surgeon, Department of Surgery, Baltimore Washington Med Ctr. 301 Hospital Drive, Glen Burnie, Maryland 21061 (included ER coverage) 2001-4 Attending Surgeon, Department of Surgery, St. Agnes HealthCare, 900 Caton Avenue, Baltimore, Maryland 21229

Cancer Liaison Physician

1997-01Assistant Professor, Division of Surgical Oncology, Department of Surgery, University of Texas Southwestern Medical Center @ Dallas, 5323 Harry Hines Blvd, Dallas, Texas 75390-9155

Director, Parkland Tumor Clinic 1998-2000, Chairman Cancer Cmte Post -Graduate Training

1995-97 Surgical Oncology Fellow - Memorial Sloan-Kettering Cancer Center, Department of Surgery, 1275 York Avenue, New York, New York 10021 (Murray F. Brennan/Dan Coit)

1993-95 Research Fellow/Instructor - Tulane University School of Medicine, Department of Surgery, 1430 Tulane Avenue, New Orleans, Louisiana 70112 (Bernard Jaffe/Ken Bost)

1988-93 General Surgery Resident - Tulane University School of Medicine, Department of Surgery, 1430 Tulane Avenue, New Orleans, Louisiana 70112 (Norman McSwain/ Lewis Flint, Jr)

Education

1984-88MD, University of Oklahoma School of Medicine, Oklahoma City, Oklahoma 1979-84BS, Chemical Engineering, University of Oklahoma, Norman, Oklahoma. Honors/Appointments

2021-2022 Chairman Infection Committee, Safety Committee Missouri Delta Medical Center

2014-2020 OSCO (Oklahoma Society of Clinical Oncology) -full board member

(Secretary/Treasurer)

2015-2017 Cancer Liaison physician Cancer Committee, Saint Francis Hospital Tulsa, Oklahoma

2013 Moment of Truth award – SRMC - Cancer treatment centers 2012-2015 Scientific Advisory Committee – Cancer treatment centers 2012-15 Cancer Liaison Physician, Southwestern Reg Med Ctr & Commission on Cancer 2011 Vice President (President Elect) Southwest Missouri Chapter of the ACOS 2011 Member At-Large, Medical Executive Committee, St. John’s Regional Med Ctr 2011 Member At-Large, QI Committee, St. John’s Regional Med Ctr 2009-11 Chairman, Cancer Committee, St. John’s Regional Medical Center 2010 Treasurer, Southwest Missouri Chapter of the Am Coll of Surg 2008-11 Medical Director, Surgical Oncology St. John's Regional Medical Center 2007 PRIDE Award – BWMC Hospital Recognition Award 2005-08 Surgical Peer Review Committee, Baltimore Washington Medical Center Human Subjects Review Committee, Baltimore Washington Medical Center 2004-2008 Surgical Advisory Committee, Baltimore Washington Medical Center 2004-08 Am College of Surgeons - Cancer Liaison Physician, BWMed Ctr 2004-08 Director, Surgical Oncology BWMC-Tate Cancer Center 2003 Beacon of Pride Award, St. Agnes Hospital, Baltimore, MD 2003 Moderator for 2ND annual ASCO Review, Baltimore, MD – Lung Cancer Update 2002-04 Surgery Representative, St. Agnes HealthCare IRB; Surgery Representative, P&T Committee; Center of Excellence Committee, ACGME Clinical Competency Cmte 2002 Moderator for the 1st Annual ASCO Review, Baltimore MD - Sarcoma 2001 Abstract Reviewer for the 4th International Gastric Cancer Congress 2000 Guest Editor for the Journal Cancer “Gastric Cancer manuscript” 2000-01 Chairman, Cancer Committee, UTSW Cancer Program

(Parkland Memorial Hospital-Zale Lipshy University Hospital combined) 1999-01 Faculty, Society of Surgical Oncology advanced laparoscopy course for Surgical oncology fellows (Sponsored by US Surgical/Tyco Corporation) 1999-01 Am College of Surgeons, Cancer Liaison Officer, Parkland Memorial Hospital 1998-01 Cancer Committee, Parkland Memorial Hospital 1997-01 Medical Director, Tumor Clinic - Parkland Memorial Hospital 1996 Sylvester Cancer Center, Miami, Florida - Travel Grant Award

(Presentation of Melanoma sentinel node step sectioning data) 1994-95 Cancer Committee, Medical Center of Louisiana-New Orleans 1993-95 Co-Director, Advanced Trauma Life Support Program, Tulane University Medical Center

1993 State Faculty Appointment, American College of Surgeons - ATLS Program 1993 M. L. Jarrell Traveling Fellowship Award (Tulane Univ Med Ctr) Societies

2000-dateFellow, American College of Surgeons

1995-00Associate Fellow, American College of Surgeons 1992-94Candidate, American College of Surgeons,

2000-dateACOS-Oncology Group, Physician Member

1995-dateSociety of Surgical Oncology

1984-dateAmerican Medical Association

1997-01Association for Academic Surgery

Parkland Surgical Society

1994-01Tulane Surgical Society

2010-15American Society of Peritoneal Surface Malignancy Abstracts/Meeting Presentations

GALLBLADDER MELANOMA (Poster and Presentation). Fred Lee MD1, Deepna Jaiswal DO2, Samuel Bieligk MD3, Pierre Greeff MD3, Guido Sclabas MD1 Univ of Oklahoma College of Medicine1,2 and CTCA3.

Presented at the Annual Resident Conference Univ of Oklahoma Tulsa 2014 Surgical Platform for Complex and Advanced Malignancy at SRMC. Samuel C. Bieligk, MD FACS; Presented at the Annual Cancer Conference Roy L. Schneider Regional Hospital & Charlotte Kimelman Cancer Institute, St. Thomas USVI. February 2014

Cytoreductive Surgery (CRS) and HIPEC in Patients with Recurrent Platinum-Resistant Ovarian Carcinoma C. Komen Brown, MD, PhD; Samuel Bieligk, MD FACS; Rod Flynn, MD; Cancer Treatment Centers of America

Presented at the 8th regional Perfusion Meeting UPMC, Steamboat Springs, Colorado February 2014

MEDICOLEGAL VULNERABILITIES IN CYTOREDUCTIVE SURGERY AND HYPERTHERMIC PERITONEAL CHEMOTHERAPY TREATMENTS FOR CARCINOMATOSIS

Samuel Bieligk ^, Nader Hanna^, and Paul Sugarbaker; Baltimore Washington Medical Center#, University of Maryland School of Medicine^, and Washington Hospital Center* Presented at the 2008 Regional Cancer Therapies Conference in Palm Springs, California February 15-19, 2008

LAPAROSCOPY ASSISTS IN STAGING PATIENTS WITH PERITONEAL CARCINOMATOSIS (PC) AND SELECTION FOR HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY (HIPEC)

Samuel C Bieligk*#, MD & Rod Flynn, MD*; Jesus Esquivel, MD^; Nader Hanna#, MD- Baltimore Washington Med Ctr*, St. Agnes Healthcare^, and University of Maryland Med Ctr# Presented 2007 ASCO, SSO, ASTRO, AGA GI Symposium; Orlando, Florida January 19-22 2007.

METASTATIC SCALP ANGIOSARCOMA PRESENTING AS A LUNG BLEB, Bashir, Ahmad A*; Sardi, Armando*; Bieligk, Samuel C. # Poster presentation at the Southeastern Surg Assoc. 3/06

THE UTILITY OF PERITONEAL CYTOLOGY IN PATIENTS UNDERGOING STAGING/ DIAGNOSTIC LAPAROSCOPY S.C. Bieligk*, J. Fleming^, R. Flynn*, A. Green, R. Ashfaq#, R. Rege^, N. Hanna*

Presented at the ASCO, SSO, & ASTRO GI Cancer Symposium Hollywood, Florida, January 2005

THE UTILITY OF LAPAROSCOPIC PERITONEAL CYTOLOGY IN PATIENTS WITH MALIGNANT DISEASE CONFINED TO THE ABDOMEN

Green, Andrew T*; Fleming, Jason B^; Ashfaq, Raheela#; Rege, Robert^; Sardi, Armando*; Bieligk, Samuel C*. Presented at the St. Agnes HealthCare Resident Research Competition Baltimore, Md 2003 (2nd place award).

THE UTILITY OF LAPAROSCOPIC PERITONEAL CYTOLOGY IN PATIENTS WITH INTRA-ABDOMINAL MALIGNANT DISEASE

Green, Andrew T*; Fleming, Jason B^; Ashfaq, Raheela#; Rege, Robert^; Sardi, Armando*; Bieligk, Samuel C* Presented at the 2003 American College of Surgeons Clinical Congress, Chicago, IL Oct. 2003

EARLY POSTOPERATIVE FEEDING IN A SURGICAL ONCOLOGY PRACTICE Sardi, A; Sher-Ahmed, A; Bieligk, S. Presented at the 55th Annual Cancer Symposium, Society of Surgical Oncology, Los Angeles, CA. March 2003. CYTOREDUCTION AND INTRAOPERATIVE PERITONEAL HYPERTHERMIC PERFUSION FOR CARCINOMATOSIS

Averbach, A; Bieligk, S; Sardi, A. Presented at the 55th Annual Cancer Symposium, Society of Surgical Oncology, Denver, CO. March 2002. LAPAROSCOPIC INTRAPERITONEAL HYPERTHERMIC CHEMOTHERAPY FOR MALIGNANT ASCITES IN PERITONEAL CARCINOMATOSIS

Leonardo Villegas, Samuel Bieligk, Jason B. Fleming, Daniel Jones, Brian Loggie*, Presented at the Society of Gastrointestinal Endoscopic Surgeons Meeting (SAGES) New York, NY October 2001

DETECTION OF ABERRANT PROMOTER METHYLATION IN CELLS FROM LAPAROSCOPIC PERITONEAL WASHINGS OF PATIENTS WITH SUSPECTED INTRA-ABDOMINAL MALIGNANCIES. Yvonne M. Feller, Samuel C. Bieligk, Jason B. Fleming, Sabine Zöchbauer-Müller, Eva Forgacs, Raheela Ashfaq, Daniel B. Jones, Carlos H. Becerra, John D Minna. Poster and Discussion Session presentation at the American Association of Cancer Research, New Orleans, Louisiana. March 2001. Proc Am Assoc Can Res, 2001; 42: 3792a.

DETECTION OF ABERRENT TUMOR SUPRESSOR GENE METHYLATION IN LAPAROSCOPIC PERITONEAL WASHINGS FROM PATIENTS WITH INTRA- ABDOMINAL MALIGNANCIES

Bieligk SC*, Fleming JB, Feller YM, Minna JD. Presented at the 54th Annual Cancer Symposium, Society of Surgical Oncology, Washington, DC. March 2001. THE UTILITY OF LAPAROSCOPY IN THE STAGING EVALUATION AND MANAGEMENT OF UPPER GASTROINTESTINAL MALIGNANCIES

Bieligk SC, Huang H, Fleming JB, Anthony T, Jones DB, Jeyarajah R, DeMaio M, Beitsch P, Huth JB, Rege RV. UTSW Medical Center at Dallas. Presented at the North Texas Chapter of the American College of Surgeons Meeting Feb 2000. THE DETECTION OF MICROMETASTASES IN MELANOMA SENTINEL NODES BY COMPLETE SERIAL SECTIONING AND IMMUNOHISTOCHEMICAL STAINING

Bieligk SC, Klimstra DS, Rosai J, Coit DG. Presented at the Annual Meeting of the American Society of Clinical Oncology, Atlanta, Georgia. May 1999. Proc Am Soc Clin Oncol, 1999; 18: 2074a.

PATIENTS WITH METASTATIC GASTRIC CANCER SELECTED BY LAPAROSCOPY FOR RESECTION HAVE LONGER SURVIVAL

RP DeMatteo*, S Bieligk, S Lahrs, M Beninati, G Schwartz, D Kelsen, MF Brennan, MS Karpeh. Presented at the 52nd Annual Cancer Symposium, Society of Surgical Oncology, Orlando, FL. March 1999.

THE MANAGEMENT OF M1 GASTRIC CANCER WITH LAPAROSCOPY AND PREOPERATIVE CHEMOTHERAPY

SC Bieligk, MF Brennan, G Schwartz, D Kelsen, MS Karpeh. Presented at the Parkland Surgical Society Annual Meeting, Vail, Colorado. June 1998. THE DETECTION OF TYROSINASE mRNA BY REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION (RT-PCR) IN MELANOMA SENTINEL NODES SC Bieligk, RA Ghossein, J Rosai, MF Brennan, S Bhattacharya, DG Coit. Presented at the 51st Annual Cancer Symposium, Society of Surgical Oncology, San Diego, CA. March 1998.

THE DETECTION OF MICROMETASTASES IN MELANOMA SENTINEL NODES BY STEP SECTIONING AND IMMUNOHISTOCHEMICAL STAINING. Bieligk SC, Klimstra DS, Rosai J, Coit DG. Melanoma Research 7 (Suppl 1): S125, 1997PERITONEOVENOUS SHUNTING FOR NON-GYNECOLOGIC MALIGNANT ASCITES

Bieligk SC, Calvo BF, Coit DG. Presented at the 50th Annual Cancer Symposium, Society of Surgical Oncology, Chicago, IL, pg. 48, March 21,1997. ENHANCED PATHOLOGIC ANALYSIS OF SENTINEL NODES FOR DEEP CUTANEOUS MELANOMAS

Bieligk SC, Klimstra DS, Rosai J, Coit DG. Presented at the 50th Annual Cancer Symposium, Society of Surgical Oncology, Chicago, IL, pg. 48, March 21,1997. Publications

•J. Esquivel1, R. Sticca2, P. Sugarbaker3, E. Levine4, T. D. Yan3, R. Alexander5, D. Baratti6, D. Bartlett7, R. Barone8, P. Barrios9, S. Bieligk10, P. Bretcha-Boix11, C. K. Chang12, F. Chu13, Q. Chu14, S. Daniel13, E. de Bree15, M. Deraco6, L. Dominguez-Parra16, D. Elias17, R. Flynn10, J. Foster18, A. Garofalo19, F. N. Gilly20, O. Glehen20, A. Gomez-Portilla21, L. Gonzalez-Bayon22, S. Gonzalez-Moreno23, M. Goodman24, V. Gushchin25, N. Hanna5, J. Hartmann26, L. Harrison27, R. Hoefer28, J. Kane29, D. Kecmanovic30, S. Kelley31, J. Kuhn32, J. LaMont32, J. Lange33, B. Li14, B. Loggie18, H. Mahteme34, G. Mann35, R. Martin36, R. A. Misih37, B. Moran38, D. Morris13, L. Onate-Ocana39, N. Petrelli37, G. Philippe40, J. Pingpank41, A. Pitroff1, P. Piso42, M. Quinones43, L. Riley44, L. Rutstein45, S. Saha46, S. Alrawi29, A. Sardi25, S. Schneebaum47, P. Shen4, D. Shibata31, J. Spellman48, A. Stojadinovic49, J. Stewart4, J. Torres-Melero50, T. Tuttle51, V. Verwaal52, J. Villar53, N. Wilkinson54, R. Younan6, H. Zeh7, F. Zoetmulder52 and G. Sebbag55Cytoreductive Surgery and Intraperitoneal Hyperthermic Chemotherapy in the Management of Peritoneal Surface Malignancies of Colonic Origin: A Consensus Statement. Annals of Surgical Oncology 14(1);2007:128-133

•Spanknebel K, Coit DG, Bieligk SC, Gonen M, Rosai J, Klimstra DS. Characterization of micrometastatic disease in melanoma sentinel lymph nodes by enhanced pathology: recommendations for standardizing pathologic analysis. Am J Surg Pathol. 2005 Mar; 29(3): 305-17.

•Wilkiemeyer, MB; Bieligk, SC; Ashfaq, R; Jones, DB; Rege, RV; Fleming, JB. Laparoscopy Alone is Superior to Peritoneal Cytology in Staging Gastric and Esophageal Carcinoma. Surg Endosc. 2004 May; 18(5): 852-6.

•DeMatteo RP, Brennan MF, Bieligk SC, Lahrs S, Beninati M, Schwartz G, Kelsen D, Karpeh MS. Outcome of Patients with Occult Metastatic Gastric Adenocarcinoma Selected for Surgical Resection Through the Use of Staging Laparoscopy. (Accepted with revisions to Annals of Surgical Oncology).

•Bieligk SC, Brennan MF. “Retroperitoneal Mass” in Surgical Decision Making. pp. 204-7 Fourth Edition.2000 Norton LW, Eiseman B, and Stiegmann G (eds.). W.B. Saunders Company, Philadelphia, Pennsylvania

•Azam M. Saboorian H. Bieligk S. Smith T. Molberg K. Cutaneous angiosarcoma complicating morbid obesity. Archives of Pathology & Laboratory Medicine. 125(4): 531-3, 2001 Apr.

•Doolabh N. Anthony T. Simmang C. Bieligk S. Lee E. Huber P. Hughes R. Turnage R. Primary colonic lymphoma. Journal of Surgical Oncology. 74(4): 257-62, 2000 Aug.

•Anthony T. Fleming JB. Bieligk SC. Sarosi GA. Kim LT. Gregorcyk SG. Simmang CL. Turnage RH. Postoperative colorectal cancer surveillance. Journal of the American College of Surgeons. 190(6): 737-49, 2000 Jun.

•Bieligk SC, Calvo B, Coit DG. Peritoneovenous Shunting for Non-Gynecologic Malignant Ascites. Cancer, 91: 1247-55, 2001.

•Smith T, and Bieligk SC. Angiosarcoma Arising in a Lymphedematous Abdominal Wall: Case Report and Review of the Literature. Surgical Rounds, 24(5): 241, 2001.

•Bieligk S, McClelland R. Melanoma. Selected Readings in General Surgery; 27(3), 2000.

•Bieligk SC, Ghossein RA, Rosai J, Bhattacharya S, Coit DG. The Detection of Tyrosinase mRNA by Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) in Melanoma Sentinel Nodes. Annals of Surgical Oncology; 6(3): 232-240, 1999.

•Bieligk SC, Burke EC, Bains MJ, Shaha A. Postirradiation Sarcoma. Surgical Rounds, 20(3): 87-93, March 1997.

•Sutherland CM, Chmiel J, Bieligk SC, Henson DE, Winchester DP. Patient Characteristics, Treatment, and Outcome of Unknown Primary Melanoma in the United States for the Years 1981and 1987. Am Surg. 62:400-6, 1996.

•Bieligk SC, Jaffe BM. “VIPoma,” in GEP and Multiple Neuroendocrine Tumors. Ed. V. Percopo and E.L. Kaplan. Piccin Nuova Libraria S.p.A., Padova. 1996; pp. 357-69.

•Bieligk S, Jaffe B. Pancreatic Islet Cell Tumors. Surg Clin North Am. 75(5): 1025-40, 1995.

•Bost K, Bieligk S, and Jaffe B. Lymphokine mRNA Expression by Transplantable Murine B Lymphocytic Malignancies: tumor-derived IL-10 as a possible mechanism for affecting the anti-tumor response. Journal of Immunology, 154:718-729, 1995.

•Bieligk S. Subungual Melanoma. Surgical Rounds, 17(7): 445-55. July 1994. Grants

2001-2003St. Agnes HealthCare Foundation$5,000

[Funds immunohistochemical evaluation of esophageal tumors based on molecular markers and retrospective outcomes analysis]

2000Southwestern Center for Minimally Invasive Surgery $12,500

[Support provided to fund the purchase of reagents, disposables and large equipment involved in the molecular analysis of peritoneal washings from patients undergoing laparoscopy for diagnosis and staging]

Clinical Research Protocols

2015(CTCA) Principal Investigator for “HIPEC in patients with peritoneal metastases from Gastric carcinoma” IRB submitted

2012(CTCA) Sub Investigator, IRB SRMC 12-02 Multi-Modality Therapy for Untreated Patients with Resectable or Marginally Resectable Pancreatic Cancer (PI: Theodore Pollock)

2011-14(CTCA) Principal Investigator for EGEN – 301-***-****-**(St Agnes) Institutional Principal Investigator of ACOSOG Intergroup trials Z9000, Z9001 “Adjuvant STI 571 Therapy for Gastrointestinal Stromal Tumors (GIST)” 2002-03(St Agnes) Institutional Principal Investigator of ACOSOG Intergroup trial Z0190 “A Prospective Study of the Prognostic Significance of Microsatellite Instability in Patients with Early Age-of-Onset Colorectal Cancer” 2001-03(St Agnes) Immunohistochemical staining of esophageal malignancies to identify prospective prognostic markers via histologic analysis 2000–01(UTSW)“Prospective Acquisition of Malignant Mucosal Cells in Gastrointestinal Malignancies before Treatment with Chemotherapy and Upon Disease Progression.” Principal Investigator, Carlos Becerra, MD Samuel Bieligk, MD Co- investigator. (IRB #0800-398)

1998-2001 “Laparoscopy in the Staging and Diagnosis of Patients with Upper Gastrointestinal Malignancies.” A study incorporating laparoscopy for the evaluation of the abdomen in patients with tumors of the distal esophagus, stomach, and pancreas. Samuel Bieligk, MD Principal Investigator. (IRB # 0898 33100) 1997“Intraoperative Mapping of Regional Lymphatics Using Lymphoscintigraphy and Isosulfan Blue to Detect and Biopsy Breast Sentinel Nodes” Modified to include the procurement of sentinel lymph node specimens for immunohistochemistry and PCR analysis. HC Cody, III, MD, Principal Investigator. Memorial Sloan-Kettering Cancer Center (Revised to include prospective molecular analysis-Trial still ongoing) 1996“Intraoperative Mapping of Regional Lymphatics Draining the Primary Site of Melanoma Using Lymphoscintigraphy and Isosulfan Blue” Modified to include the procurement of sentinel lymph nodes prospectively for tyrosinase PCR analysis. DG Coit, Principal Investigator. Memorial Sloan-Kettering Cancer Center (Revised to include prospective molecular analysis-Trial still ongoing) 1995“PHASE I trial of B-7 augmented Her-2-neu vaccine for stage IV, failed first line therapy, breast cancer patients” Maroggi E, Bieligk S, Freeman S. Tulane University Medical Center, New Orleans, LA.

Research

2000-01The detection of hypermethylated tumor suppressor genes in peritoneal washings from patients undergoing laparoscopy for staging and diagnosis of intra-abdominal malignancies. With the assistance of John Minna, MD from the Hamon Center for Therapeutic Oncologic Research

1998-99The detection of peritoneal tumor using Ber-EP4 (Epithelial Glycoprotein) from the cytologic washings of patients with UGI malignancies. With the assistance of Adi Gazdar, MD and John Minna, MD from the Hamon Center for Therapeutic Oncologic Research

1997-98The detection of melanoma micrometastases using MIA, MAGE-3, and Tyrosinase in sentinel node specimens. With the assistance of Adi Gazdar, MD and John Minna, MD from the Hamon Center for Therapeutic Oncologic Research 1996-97RT-PCR for the detection of tyrosinase mRNA in melanoma patients sentinel node specimens. With the direction of Ronald Ghossein, MD from the Dept. of Pathology and Daniel G. Coit, MD from the Department of Surgery, Memorial Sloan- Kettering Cancer Center, New York, New York.

1998-2001DETECTION OF ABERRANT PROMOTER METHYLATION IN CELLS FROM LAPAROSCOPIC PERITONEAL WASHINGS OF PATIENTS WITH SUSPECTED INTRA- ABDOMINAL TRACT MALIGNANCIES.

Yvonne M. Feller,* Samuel C. Bieligk,§ Jason B. Fleming,§ Sabine Zöchbauer-Müller,* Eva Forgacs,* Raheela Ashfaq, Daniel B. Jones,§ Carlos H. Becerra, John D Minna* ¥ Hamon Center for Therapeutic Oncology Research* and Departments of Internal Medicine, Pharmacology¥, Surgery§, and Pathology .

University of Texas Southwestern Medical Center, Dallas TX 1993-95RT-PCR of tumor for cytokine analysis and anti IL-10 immunotherapy in a murine B-cell lymphoma model. Collaborative Project with Ken Bost, Ph.D. from the Department of Microbiology and Immunology, and Bernard M. Jaffe, MD with the Department of Surgery. Tulane Medical School. New Orleans, Louisiana. 1984-85Red blood cell deformability in patients with renal insufficiency undergoing hemodialysis . Collaborative project with the University of Oklahoma College of Medicine, Department of Nephrology (David Smith, MD) and the Chemical Engineering Department (E.A. O'Rear, Ph.D.) at the University of Oklahoma, Norman, Oklahoma.

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