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Personal Information

Name Khalid Ayub Jadoon

Date of Birth 27th February 1975

Nationality British

Address ** ********** ****, *******, *** 3AD, West Midlands UK Email advn66@r.postjobfree.com, advn66@r.postjobfree.com Full Registration with General Medical Council UK with License to Practice (Reg No. 6035544) Consultant Physician & Endocrinologist Royal Wolverhampton NHS Trust Honorary Clinical Associate Professor School of Biomedical Sciences, University of Birmingham Recipient of clinical excellence award level 1 for commitment and dedication Professional Qualifications/Memberships

FRCP Royal College of Physicians (London) UK 31/12/2021 PhD University of Nottingham 16/12/2016

CCT General Medical Council UK 27/08/2015

MRCP (Endo & Diab) Royal College of Physicians London 21/07/2014 MRCP (UK) Royal College of Physicians London 19/07/2006 MBBS University of Peshawar Pakistan 31/12/1999

Employment History

I started my postgraduate training in Diabetes & Endocrinology in 2008 and worked at various district general and university hospitals in the East Midlands Deanery of the UK until my CCT in August 2015. During my training, I spent three years to undertake basic and clinical research, investigating the role of cannabinoids in type 2 diabetes and cardiovascular disease, and as a result the University of Nottingham awarded me with doctoral degree in December 2016. I am currently working as Consultant in Diabetes & Endocrinology, at The Royal Wolverhampton Hospitals NHS Trust. I have summarized my employment history below. Consultant Endocrinologist Royal Wolverhampton Hospitals NHS Trust June 2016 to date Consultant Endocrinologist University Hospitals of Nottingham NHS Trust July 2015 - May 2016 Specialist Registrar University Hospitals of Nottingham NHS Trust June 2014 - June 2015 Clinical Research Fellow University of Nottingham Feb 2011 - May 2014 Specialist Registrar Sherwood Forest Hospitals NHS Trust Aug 2010 - Jan 2011 Specialist Registrar University Hospitals of Nottingham NHS Trust Aug 2009 - Jul 2010 Specialist Registrar United Lincolnshire Hospitals NHS Trust April 2008 - Jul 2009 Roles and Responsibilities

Mortality lead for Diabetes directorate

Clinical lead for Cystic Fibrosis related Diabetes Mortality Reviewer – part of learning from death initiative by RCP London Senior Academy Tutor Wolverhampton Medical Institute for 4th year medical students OSCE examiner – University of Birmingham UK

Clinical and Educational Supervisor for Internal Medicine Trainees and senior clinical fellows 2

Current Job Commitments

Outpatient work;

Type 1 diabetes including Insulin pump therapy with use of CGM technology Type 2 diabetes and chronic kidney disease

Diabetic Foot disease

Cystic fibrosis related Diabetes

Parathyroid, Pituitary, Adrenal and Reproductive Endocrinology Thyroid disease and Radio Active Iodine

Inpatient work involves;

Daily review of general medical and diabetic patients Leading acute medical take on pro rata basis

Supporting other specialties in managing inpatient diabetes/endocrine related problems Teaching Commitments

Teaching 3rd and 4th year medical students, clinical nursing staff and Family Physician colleagues Senior Academy Tutor with mentoring responsibilities for 4th year medical students Three years experience as Teaching Fellow during clinical research from Feb 2011 to May 2014 OSCE examiner 3rd and 5th year medical students (University of Birmingham Medical School) To enhance my teaching skills, I have attended various courses including,

• Professional support & Engagement (University of Birmingham)

• Teaching and Assessing Clinical Skills (University of Nottingham)

• Teaching Improvement Programme System (University of Nottingham)

• Physicians as Educators (Royal College of Physicians UK) Management Training and Experience

First hand experience of managing a team consisting of junior medical colleagues and allied healthcare professionals in providing holistic patient care while maintaining highest standards of professionalism. Attendance at following management and leadership courses during higher medical training; 2015: Management and Leadership course: Two-day intensive course preparing specialist trainees to face up to the challenges of a busy and rapidly changing healthcare system. 2015: Pre-consultant course: Developing skills to work effectively as a consultant in a busy healthcare system whilst maintaining the right work-life balance. 2014: Commissioning and Diabetes Service Re-design: A full day session organized for specialty trainees in endocrinology and diabetes.

Research

I investigated the metabolic and cardiovascular effects of two phytocannabinoids, Cannabidiol (CBD) and Tetrahydrocannabivarin (THCV), in type 2 diabetes and the effects of CBD on cardiovascular response to stress in healthy volunteers, in phase 2 clinical trials. My research showed that THCV improved glycaemic handling after an oral glucose load while CBD reduced cardiovascular response to stress. In addition, part of research involved looking at the effects of these two compounds on adipocytes and vascular endothelial cells and I was awarded PhD for my work by University of Nottingham in December 2016. 3

Publications

Jadoon KA, Tan GD, O'Sullivan SE. A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study. JCI Insight. 15;2(12). Wheal AJ, Jadoon K, Randall MD, O'Sullivan SE. In Vivo Cannabidiol Treatment Improves Endothelium- Dependent Vasorelaxation in Mesenteric Arteries of Zucker Diabetic Fatty Rats. Front Pharmacol.18;8:248. Jadoon KA, Ratcliffe SH, Barrett DA, Thomas EL, Stott C, Bell JD, O'Sullivan SE, Tan GD. Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study. Diabetes Care. 39(10):1777-86.

Jadoon K, Idris I. Dapagliflozin: A Once-Daily Oral Therapy Sodium-Glucose Cotransporter-2 Inhibitor for the Treatment of Adult Patients with Type 2 Diabetes. Clinical Medicine Insights: Therapeutics 2011:3 185–194 Jadoon K, Wijngaart H, Olczak S. Bariatric Surgery does not cure all Type 2 Diabetes. BMJ Case Reports 2009

[doi:10.1136/bcr.08.2008.0755]

Wilmot EG, Jadoon KA, Olczak SA. Charcot's neuroarthropathy of the wrist in type 2 diabetes. Practical Diabetes International 2008; 25(7): 263

Presentations and Posters

2021: Effect of age on parathyroid hormone response to vitamin D insufficiency in primary hyperparathyroidism – E poster - Annual European Congress of Rheumatology EULAR 2021 2020: Effect of vitamin D on parathyroid hormone, serum calcium and bone mineral density in patients with primary hyperparathyroidism being managed conservatively – Accepted as E poster for British Rheumatology Society 2021 Annual Conference

2019: Investigating the Use and Frequency of Blood Glucose Monitoring in Hospital Inpatients with Stable Non-insulin Dependent Diabetes – Poster presentation at EASD 2019 Barcelona Spain 2015: Cannabidiol (CBD) decreases resting blood pressure and blood pressure response to stress in healthy volunteers – Poster presentation at International Cannabinoid Conference Italy 2015 2014: THCV improves glycaemic control in type 2 diabetes – Poster presentation Diabetes UK, Annual Professional Conference 2014

Language Skills

Fluent in English, Urdu, Hindi and Punjabi

References

Available on request

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