Research Specialist Associate

Dr. KALPITA BANERJEE, PhD

aduanx@r.postjobfree.com

Ph: +1-423-***-****

New York, NY

Permanent resident/Green Card

https://www.linkedin.com/feed/

SUMMARY:

• Passionate molecular biology scientist, made a substantial contribution to the field of molecular biology with a focus on identifying novel targets involved in several biological disorders.

• Worked in an academic environment, with a group or individually, to lead multiple projects for signaling, drug target and therapeutic development.

• Worked with a cross-disciplinary team withing the same Institute or with national/international collaborators for the execution of the required experiments and for the best outcome of the projects.

• 10 years of combined experience in working with diverse cell line and with mice/rat or human samples to understand various cellular pathways involved in metabolic or neurological diseases.

• Successfully identified few possible novel drug target pathways which can control different cell death mechanism (apoptosis/necroptosis/autophagy etc.) and specifically to arrest a broad range of diseases including aging disease, oncology related and others.

• Hands on experience in core facility operations and customer dealing, lab management, grant writing (2), paper writing (15), paper reviewing (60+), editorial management, oral and poster presentation/judge, protocol/assay development and train to junior employees/students (2014 Siemens Competition in Math, Science and Technology, I was listed as research project mentor for 1 of 10 shortlisted).

• Number of citations of my research work: >600

AREAS OF EXPERTISE:

Standardize, develop and implemented new experiments and protocols and improve laboratory workflow efficiency. Assay development (cell based, biochemical etc.) with various technology including the following:

• Western Blot, Co-IP, Immunocytochemistry, Immunohistochemistry

• DNA-RNA Isolation, PCR, qPCR, Transfection

• Epigenomics, single cell RNA, library prep, sequencing

• Subcellular fractionation, Biochemical assays, Enzyme assays

• Confocal Microscopy

• Flow Cytometry & CRISPR(Basic)

• Cell culture

• OCT (Mouse eye), Mitochondria isolation from Rat brain

• Computer/statistical software: Microsoft office, Photoshop, GraphPad Prism SCIENTIFIC AND RESEARCH EXPERIENCE:

Research Specialist: 2021-ongoing

Weill Cornell Medical College

I am working in Epigenomic core facility focusing on single cell RNA sequencing, DNA methylation and sequencing, library preparation and implementation of multiple applications of epigenomics in variable research including cancer and precision medicine.

Postdoc Associate: 2017 - 2021

Weill Cornell Medical College

I was working on retinal degeneration and its association with ER stress, other signaling pathways and drug development. Our main aim is to identify the main damaging pathway and to develop a therapeutic target against vision loss. Research Associate: 2015 - 2017

East Tennessee State University

I was working on ER stress and its association with mitochondria and the induction of cell death in spinal cord injury/stroke model. Postdoctoral research scholar: 2012 - 2015

Burke-Cornell Medical Research Institute.

I was working on the topic of neurodegenerative diseases. My focus was on mitochondrial damage in Alzheimer’s disease model with special emphasis on α- ketoglutarate dehydrogenase enzyme.

EDUCATION:

PhD, BIOCHEMISTRY (Molecular Neuroscience)

Calcutta University, India 2005 - 2011

My doctoral work was focused on Parkinson’s disease and aging. Specifically, the effect of a-synuclein and dopamine on mitochondria and neuronal cell death PUBLICATION:

https://scholar.google.com/citations?hl=en&user=8sbb9gAAAAJ&view_op=list_works&sortby=pubdate

(Lastest 3 published)

1. Pan C, Banerjee K@, Lehmann G, Almeida D, Hajjar KA, Benedicto I, Jiang Z, Radu A R, Thompson D, Boulan ER and Nociari MM (2021) Lipofuscin causes atypical necroptosis through lysosomal membrane permeabilization. PNAS.

[@equal first authorship]. PMID 34782457.

2. Banerjee K, Keasey MP, Razskazovskiy V, Visavadiya NP, Jia C, Hagg T (2017) Reduced FAK-STAT3 signaling contributes to ER stress-induced mitochondrial dysfunction and death in endothelial cells. Cellular Signaling. PMID 28495589. 3. Visavadiya NP, Banerjee K, Keasey MP, Razskazovskiy V, Cuihong J, Hagg T

(2016) Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3. Cell Commun Sig. PMID 27978828.

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