Research Assistant Associate

Curriculum Vitae

Qi Zhou

Email: *************@*****.***

Citizenship: Canada

Education

Master Degree in Biology Jan. 2001-May 2003

Department of Biology

College of Arts and Sciences

Saint Louis University Graduate School

Saint Louis, MO USA

Associate Degree in Clinical Laboratory Medicine Sept.1985-July 2008

Peking Union Medical College

Beijing, China

Employment History

Researcher Professor, July 2012-Feb. 2017

National Center for Clinical Laboratories

Beijing, China

Research Associate Professor, June 2006-April 2008 & Feb. 2009-July 2012

National Center for Clinical Laboratories

Beijing, China

Research Assistant, July 2003-June 2006

National Center for Clinical Laboratories

Beijing, China

Job Descript: Design research projects, apply for research grants, analyze data, develop of software, and write research paper and so on.

Sr. Technician, Aug. 2008-Feb. 2009

Stero-Chrom Analytical Laboratory

Burnaby, BC Canada

Job Descript: Process human samples, extract dry blood, and analyze food allergen using ELISA method.

Researcher, Apr. 2008-July 2008

IND Diagnostic Inc

Delta, BC Canada

Job Descript: Search literatures, design research project and do pre-experiments on development of analytical kit for amino-transferase.

Research Assistant, July 1996-July 1998

Department of Cell Biology

Duke University Medical Center

Durham, NC USA

Job Descript: Do experiments in the fields of immunity, cell biology and molecular for cancer researches.

Technician/Sr. Technician, Sept. 1988-July 1996 & July 1998-Jan. 2001

Eye Research Center

Peking Union Medical College Hospital

Beijing, China

Job Descript: Do experiments in the field of biochemistry and cell biology.

Grants

1.2013 National Natural Science Foundation of China with the title “Deletion of outliers and establishment of target values in the external quality assessment program”

2.2007 International travel grant from American Associate of Clinical Chemistry

3.2007 Scientific and technical activities for studying abroad scholars from Ministry of Human Resource with the title “Calibration verification and external quality assessment”

4.2005 Scientific and technical activities for studying abroad scholars from Ministry of Human Resource with the title “Linearity survey and external quality assessment”

Achievement

Publications

1.Qi Zhou, Tianjiao Zhang, Simen Ren, Xiaopeng Li, Jihong Hu, Shaonan Li, Zhenxiang Gao. Comparison of the target values established using a robust statistical method and Roche's calibration values. Clin. Lab. 62:205*-****-****

2.Qi Zhou, Jihong Hu, Xiaopeng Li, Shaonan Li, Zhengxiang Gao, Wei Xie, Jianping Xu. Comparison of traditional, trimmed traditional and robust Youden charts. Clin Chim Acta 446:213-***-****

3.Qi Zhou, Jihong Hu, Xiaopeng Li, Shaonan Li, Zhengxiang Gao, Jianping Xu, Wei Xie. Construction and application of the robust Youden plot in an EQA program. Accred Qual Assur 20:195-***-****

4.Zhihong Qi, Fang Zhang, Wanchun Dan, Xiaoyue Liang, Yu Chen, Xiaopeng Li, Qi Zhou. Analytical performance of the Biosino urea reagent kit. Clin Lab 60:183*-****-****

5.Qi Zhou, Xiaopeng Li, Wei Xie, Jianping Xu, Shaonan Li, Jian Guo. Calibration verification for Olympus and Hitachi automatic biochemistry analyzer using albumin. Clin Lab 58:153-159, 2012

6.Qi Zhou, Jianping Xu, Wei Xie, Shaonan Li, Xiaopeng Li. Use of robust ZB and ZW to evaluate proficiency testing data. Clin Chim Acta 412:936-939, 2011

7.Qi Zhou, Jianping Xu, Wei Xie, Shaonan Li, Xiaopeng Li. Linearity study of blood calcium test. Clin Lab 57:327-331, 2011

8.Qi Zhou, Ziyu Shen, Shaonan Li, Xiaopeng Li, Wei Wang, Zhiguo Wang. Robust and traditional statistical methods in the establishment of immunoglobulin E target values in external quality assessment program. Clin Chim Acta 387:66-70, 2008

9.Qi Zhou, Shaonan Li, Xiaopeng Li, Wei Wang, Zhiguo Wang. Comparability of five analytical systems for the determination of T3, T4 and TSH. Clin Chem Lab Med 44:1363-1366, 2006

10.Qi Zhou, Shaonan Li, Xiaopeng Li, Wei Wang, Zhiguo Wang. Detection of outliers and establishment of targets in external quality assessment programs. Clin Chim Acta 372:94-97, 2006

11.Qi Zhou, Wei Xie, Jianping Xu, Shaonan Li, Xiaopeng Li. Calibration verification for blood glucose test in automatic biochemistry analyzers. Chin J Lab Med 35:317-321, 2012 (Chinese)

12.Qi Zhou, Wei Xie, Jianping Xu, Shaonan Li, Xiaopeng Li. Use of robost Z-score to assess creatinine proficiency testing data. Chin J Lab Med 34:1144-1148, 2011 (Chinese)

13.Qi Zhou, Jianping Xu, Wei Xie, Shaonan Li, Xiaopeng Li. Creatinine linear investigation in various assay instruments. Chin J Lab Med 33:782-785, 2010 (Chinese)

14.Qi Zhou. Establishment of targets for immunoglobulin E in external quality assessment program. Lab Med 24:548-551, 2009 (Chinese)

15.Qi Zhou, Shaonan Li, Xiaopeng Li, Wei Wang, Zhiguo Wang. Explore how to detect the outliers in external quality assessment. Chin J Lab Med 30:214-216, 2007 (Chinese)

16.Qi Zhou, Shaonan Li, Xiaopeng Li, Wei Wang, Zhiguo Wang. Evaluation of linearity using the newly approved NCCLS EP6-A Protocol. Chin J Lab Med 29:85-86,2006 (Chinese)

17.Qi Zhou, Shaonan Li, Xiaopeng Li, Wei Wang, Zhiguo Wang. The linearity survey of testing clinical chemical analytes. Lab Med 21(3):222, 2006 (Chinese)

18.Qi Zhou, et al. Comparison of traditional and robust Youden charts. Clin Chem Lab Med (suppl) 53 S1001 2015

19.Qi Zhou, et al. Calibration verification for Hitachi and Olympus automatic biochemistry analyzer with testing blood glucose. Clin Chem (suppl) 57(10) A-135 2011

20.Qi Zhou, et al. Linearity study on testing creatinine with various assay instruments. Clin Chem (suppl) 56(6) A-39 2010

21.Qi. Zhou, et al. Detection of outliers in external quality assessment programs. Clin Chem (suppl) 52(6) D-98 2006

22.Qi. Zhou, et al. Evaluation of linearity using the newly approved NCCLS EP6-A guideline and Dr. Kroll’s EP6-A extended methods. Clin Chem (suppl) 52(6) D-99 2006

23.Qi Zhou, et al. Comparison on performances of analytical systems for measurements of T3, T4 and TSH by external quality assessment. Clin Chem (suppl) 51(6) B-115 2005

24.WN Qi, ZQ Yan, PG. Wang, Q Zhou, LE Chen, AV. Seaber, JS. Stamler, JR. Urbaniak. Gene and protein expressions of nitric oxide synthases in ischemia-reperfused peripheral nerve of the rat. AJP-Cell Physiology 281:3 C849-856, 2001

25.SP Scully, KR Berend, A Toth, WN Qi, Q Zhou, JA Block. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma. Clin Orthop. Jul (376):291, 2000

26.WN Qi, ZQ Yan, Q Zhou, LE Chen, AV Seaber, SP Scully, JR Urbaniak. Ischemia/reperfusion mediates dual-phase change of nitric oxide syntheses mRNA expression in skeletal muscle of adult rats. Tran ORS 24:234, 1999

27.WN Qi, Q Zhou, LE Chen, AV Seaber, SP Scully, JR Urbaniak. Regulation of age factor on gene expression of nitric oxide syntheses in ischemia/reperfused peripheral nerve. Tran ORS24:980, 1999

28.Li WY, Zhou Q, Qin M, Hu TS: Reduction of inositol triphosphate in retinal microvessels by glucose and restimulation by myo-inositol. Exp. Eye Res.45:517 1987

29.Li WY, Tang L, Zhou Q, Qin M, Hu TS: DNA-synthesis regulation and correlation with inositol trisphosphate levels in cultured bovine retinal capillary pericytes. Exp. Eye Res. 49:677 1989

30.Li WY, Zhou Q, Qin M, Hu TS: The biochemical mechanism in vitro of pericyte drop-out in diabetic retinopathy. Chin J Ophthal 25:222 1989 (Chinese)

31.Li WY, Zhou Q, Qin M, Hu TS: Abnormal inositol phospholipids metabolish as a main factor causing pericyte drop-out in diabetic retinopathy. Acta Acad Med Sinic 11:395, 1989 (Chinese)

32.Li WY, Tang L, Zhou Q, Qin M, Ye XD, Hu TS: Attenuation of phosphoinositidase activity and phosphatidylinositol bisphosphate level of bovine retinal capillary pericytes in high glucose. Exp. Eye Res. 48:99 1989

33.Zhou Q, Pang GX, LI WY: Prostaglandin-mediated intercellular communication between corneal endothelial cells and platelets in vitro. Chin Ophthal Res 8:147, 1990 (Chinese)

34.Li WY, Zhou Q, Qin M, Hu TS: Intramural pericyte degeneration in early diabetic retinopathy study in vitro. Chin. Med. J 103:7, 1990 (Chinses)

35.Li WY, Zhou Q, Qin M, Tao L, Hu TS: Reduced absolute rate of myo-inositol biosynthesis of cultured bovine retinal capillary pericytes in high glucose. Exp. Eye Res. 52:569 1991

36.Qin M, Liu XP, Zhou Q, Tao L, Li WY: The frozen bovine RPE ells release a resolvable material which can promote the proliferation of RPE cells Acta Acad Med Sinic 16:462, 1994 (Chinese)

Development of Software

1.Linearity evaluation

2.Calibration verification

3.Deletion of outliers and establishment of robust target values (Patent No:

4.Robust z-scores to assess EQA data

5.Robust Youden plot to illustrate EQA data

Application

The studies on deletion of outliers and establishment of robust target values have been applied in the blind-testing program of Beijing Center for Clinical Laboratory Improvement and mutual recognition program of Beijing-Tianjing-Hebei.

Skills

Advanced data analysis, cell culture, tissue culture, southern, northern and western blotting, SDS-PAGE, ELISA, PCR, HPLC, protein purification, RNA extraction, DNA extraction, hybridization, chromatography, immune precipitation, immune staining, SPSS, Excel, PowerPoint, Word, and so on.

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