CURRICULUM VITAE

A. Personal Information:

Name

Charles F. Sharp, Jr., M.D.

Business Address

Huntington Hospital

*** **** ********** *********

Pasadena, CA 91105

Business Phone

626-***-****

Home Phone

626-***-****

Citizenship

U.S.A

E-Mail Addresses

adtm6h@r.postjobfree.com, mailto:adtm6h@r.postjobfree.com@gmail.com

B. Education:

High School

Coral Gables Senior High, Coral Gables, FL, 1962

College or University

Vanderbilt University, Nashville, TN, BA 1966

Medical School

University of Miami, Coral Gables, FL MD 1970

Internship

LAC/USC Medical Center Los Angeles, CA 1970-71

Residency

LAC/USC Medical Center, Internal Medicine, Los Angeles, CA 1971-71 and 1974-75

Fellowship

Clinical Research Fellow Diabetes/Ortho Service Rancho Los Amigos Hospital, Downey, CA 1975-76

Clinical Research Fellow Section of Endocrinology, LAC/USC Medical Center, Los Angeles, CA 1976-78

Medical Licensure Number

NPI

California G21537

Board Certification

Internal Medicine, 1976

Endocrinology/Metabolism, 1977

Geriatric Medicine, 1990-2010

C. Professional Background:

Academic Appointments

Assistant Professor of Medicine, University of Southern California School of Medicine, Los Angeles, CA, 1978–1984

Associate Professor of Clinical Medicine, University of Southern California School of Medicine, Los Angeles, CA, 1984-1991

Clinical Associate Professor of Medicine, University of Southern California School of Medicine, Los Angeles, CA, 1991-2014

Associate Professor of Clinical Medicine, Division of Endocrinology

Keck School of Medicine of USC, April 2014-September 30, 2019

Emeritus Professor of Medicine, Huntington Hospital 2015-present

Clinical Administrative Appointments

Chief, Outpatient Metabolic Bone Disease Clinic, Orthopaedic Hospital 1979-1984 Director, Osteoporosis Treatment Center, Orthopaedic Hospital, 1984- 1988

Associate Program Director, Internal Medicine Residency, Huntington Memorial Hospital, 1988-present

Chief, Section of Endocrinology, Huntington Memorial Hospital, 1991-present

Vice President, Medical Staff, Huntington Memorial Hospital, 2007-2008

President, Medical Staff, Huntington Memorial Hospital, 2009-2010

Military Service

United States Army, Repubic of Vietnam, 1972-1973

United States Army, Ft McArthur, San Pedro, CA 1973-74

D. Society Memberships:

Endocrine Society, 1980-Present

American Society for Bone and Mineral Research Entry 1982-Present

American College of Nutrition 1985-2012

American College of Physicians 1977-2019

Association of Program Directors in Internal Medicine 1989-2012

E. Research Activities:

Major Areas of Research Interest

Therapy of Metabolic Bone Diseases

Trace Elements in Metabolic Bone Disease

Changes in bone density with diet and exercise

Effect of smoking on fracture healing and bone metabolism

History of Medicine

Research Grants

Sandoz Laboratories 411 Calcitonin Injectable in the Treatment of Established Osteoporosis 1990-91

Sandoz Laboratories 320 Calcitonin Nasal Spray in the Treatment of Established Osteoporosis 1991-1995

Eli Lilly Pharmaceuticals Raloxifene In the Treatment of Established Osteoporosis 1994-1998

F. Bibliography:

Peer Reviewed

1.Rude RK, Oldham SB, Sharp CF Jr, Singer FR: Parathyroid hormone secretion in magnesium deficiency. J Clin Endocrinol Metab 47:800-806, 1978.

2.Sharp C, Bessman A, Wagner F Jr, Garland D: Microbiology of deep tissue in diabetic gangrene. Diabetes Care 1:289-292, 1978.

3.Sharp C, Bessman A, Wagner F Jr, Garland D, Reece E: Microbiology of superficial and Deep Tissues in Infected Diabetic Gangrene. Surg Gynecol Obstet 149:217-219, 1979.

4.Singer FR, Sharp CF Jr, Rude RK: Pathogenesis of hypercalcemia in malignancy. J Min Elec Metab 2:161-178, 1979.

5.Rude RK, Sharp CF Jr, Fredericks RS, Elbaum N, Link J, Irwin L, Singer FR, Urinary and nephrogenous adenosine 3’5’-monophosphate in hypercalcemia of malignancy. J Clin Endocrinol Metab 52:765-771, 1981.

6.Minkin C, Fredericks RS, Pokness S, Rude RK, Sharp CF Jr, Tong M, Singer FR: Bone resorption and humoral hypercalcemia of malignancy; stimulation of bone resorption in vitro by tumor extracts is inhibited by prostaglandin synthesis inhibitors. J Clin Endocrinol Metab 53:941-947, 1981.

7.Sharp CF Jr, Rude RK, Terry R, Singer FR: Abnormal bone and parathyroid histology in carcinoma patients with pseudohyperparathyroidism. Cancer 49:1449, 1982.

8.Gottlieb S, Rude RK, Sharp CF Jr, and Singer FR: Humoral hypercalcemia of malignancy: A syndrome in search of a hormone. American J Med 73:751-755, 1982.

9.Sharp CF Jr, Kaptein EM, Quoin V’verde ., Singer FR, Massry SG, Feinstein EI, Nicoloff JT: Serum thyroid hormone indexes in patients with primary hyperparathyroidism. Arch Int Med 144:313-315, 1984.

10.Sharp CF Jr: Humoral hypercalcemia of malignancy: The role of parathyroid hormone. New York State J Med 85:235-236, 1985.

11.Kirk SE, Sharp CF Jr, Elbaum NE, Endres DB, Simons SM, Mohler JG, Rude RK: Effect of Long Distance Running on Bone Mass in Women. J Bone Min Res 4:515-522, 1989.

12.Endres DB, Villanueva R, Sharp CF Jr, Singer FR: Measurement of Parathyroid Hormone. Endocrinol Metab Clin North Am 18:611-629, 1989.

13.Endres DB, Villanueva R, Sharp CF Jr, Singer FR: Immuno-Chemiluminometric and immunoradiometric determination of intact and total immunoreactive parathyrin: performance in differential diagnosis of hypercalcemia and hypoparathyroidism. Clin Chem 37(2):162-168, 1991.

14.Gruber HE, Gonick HC, Kahalil-Manesh F, Sanchez TV, Motsinger S, Meyer M, Sharp CF Jr: Osteopenia Induced by Long-Term, Low- and High-Level Exposure of the Adult Rat to Lead. Miner Electrolyte Metab 232:65-73, 1997.

15.Caillouette JC, Sharp CF Jr, Zimmerman GJ, Roy S: Vaginal pH as a marker for Bacterial Pathogens and Menopausal Status. Am J Obstet Gynecol 176(6):1270-1277, 1997.

16.Gruber HE, Rude RK, Sharp CF, Ryzen E, Singer FR: Adult Acquired Hypophosphatemic Osteomalacia: Bone Biopsy and Skeletal Features in Two Patients

Annals of Orthopedics and Musculoskeletal Disorders 1 (2) 2018

Book Chapters/Special Articles:

1.Sharp, C.F., Jr. and Singer, F.R.: In: Current Therapy in Endocrinology 1983-84, pp. 266-269, B.C. Decker, Inc., Krieger, D. and Barding, W. eds.

2.Singer, F.R., Sharp, C.F., Jr., Ryzen, E. and Rude, R.K.: Humoral Hypercalcemia Of Malignancy: Role of Parathyroid Hormone and Prostaglandin E2. In: Clinical Disorders of Bone and Mineral Metabolism pp288-290, Excerpta Medica; Boy Frame and John Potts eds., 1983.

3.Sharp, C.F. Jr.: Exercise for the Patient with Osteoporosis. In: Reach for Fitness

A Special Book of Exercise for the Physically Challenged, pp 280-282, Simmons, Richard. Warner Books, 1986

4.Sharp, C.F., Jr., Retrospective on Osteoporosis and the Use of Calcitonin-Salmon. In: New Strategies in the Management of Established Osteoporosis. Proceedings of Calcimar Dialectic, a closed symposium, November 18-19, 1988, Phoenix, Arizona. A publication of Rorer Pharmaceuticals.

5.Sharp, C.F., Jr.: Kidney Stones. Cortlandt Forum March, 1992 pp. 236-245.

Abstracts:

1.Sharp, C.F., Jr. and Bessman, A.M.: Microbiology of deep wound cultures in diabetic gangrene. Diabetes 25(1):385, 1976.

2.Sharp, C.F., Jr. and Bessman, A.M.: Anaerobic bacteria in diabetic gangrene. Clin. Res. 25:123, 1977.

3.Rude, R.K., Oldham, S.B., Sharp, C.F., Jr. and Singer, F.R.: Effect of magnesium on parathyroid hormone secretion in man. Program of the Sixth Parathyroid Conference, p. 30, 1977.

4.Rude, R.K., Link, J., Sharp, C.F., Jr., Oldham, S.B., Elbaum, L., Irwin, L. and Singer, F.R.; Elevation of plasma cAMP in the hypercalcemia of malignancy. Program of the American Association for Cancer Research, p. 134, 1977.

5.Rude, R.K., Oldham, S.B., Sharp, C.F., Jr. and Singer, F.R.: Parathyroid Hormone secretion in magnesium deficiency. Program of the Fifty-Ninth Annual Meeting of the Endocrine Society, p. 235, 1977.

6.Rude, R.K., Oldham, S.B., Sharp, C.F., Jr. and Singer, F.R.: Effects of magnesium on parathyroid hormone in man. Program of the Third International Workshop in Phosphate and other Minerals. Madrid, Spain, 1977.

7.Sharp, C.F., Jr., Rude, R.K., Oldham, S.B., Terry, R. and Singer, F.R.: Abnormal Bone and parathyroid histology in pseudohyperparathyroidism. Clin. Res. 26:428, 1978.

8.Sharp, C.F., Jr., Rude, R.K., Oldham, S.B. and Singer, F.R.: Familial hypercalcemia. Clin. Res. 26:428, 1978.

9.Rude, R.K., Sharp, C.F., Jr., Oldham, S.B. and Singer, F.R.: Plasma cyclic AMP, urinary cyclic AMP, and nephrogenic cyclic AMP in the hypercalcemia of malignancy. Clin. Res. 26: 427, 1978.

10.Rude, R.K., Sharp, C.F., Jr., Oldham, S.B. and Singer, F.R.: Studies of the pathogenesis of pseudohyperparathyroidism. Clin. Res. 26:427, 1978.

11.Sharp, C.F., Jr., Oldham, S.B., Fredericks, R.S., Quismonio, F.P., Jr., Rude, R.K. and Singer, F.R.: Parathyroid Hormone in Non-parathyroid Tumors: A Cause for Hypercalcemia? Program of the Sixty-First Annual Meeting of the Endocrine Society, p. 85, 1979.

12.Sharp, C.F., Jr., Rude, R.K., Oldham, S.B., Terry, R. and Singer, F.R.: Abnormal Bone and parathyroid histology in pseudohyperparathyroidism. Program of the Sixth International Congress of Endocrinology. Melbourne, Australia, p. 304, 1980

13.Minkin, C., Fredericks, R., Rude, R.K., Sharp, C.F., Jr., Oldham, S.B.and Singer, F.R.: Humoral hypercalcemia of malignancy: Characterization of bone resorbing activity in tumor extracts. Program of the Second Annual Meeting of the American Society for Bone and Mineral Research, p. 16, 1980.

14.Rude, R.K., Sharp, C.F., Jr. and Singer, F.R.: Abnormal tubular maximum for magnesium (TmMg) in familial hypocalciuric hypercalcemia (FHH). Presented at the Western Section meeting of the AFCR, Carmel, California 2-4 to 6-8. Clin. Res. 29:59, 1981

15.Sharp, C.F., Jr., Rude, R.K. and Singer, F.R.: Parathyroid hormone in human carcinomas: A doubtful cause of hypercalcemia. Clin. Res. 29:98, 1981

16.Sharp, C.F., Jr., Rude, R.K. and Singer, F.R.: Immunoreactive parathyroid hormone in human carcinomas using an homologous human parathyroid hormone radioimmunoassay. Program of the Sixty-Fourth Annual Meeting of the Endocrine Society, P. 1393, 1982.

17.Rude, R.K., Kirk, S., Elbaum, N. and Sharp, C.F., Jr.: Correlation of cortical and trabecular bone mass in women. Program of the Eighth Annual Meeting of the American Society for Bone and Mineral Research, June, 1986.

18.Sharp, C.F., Jr. and Singer, F.R.: Sodium Fluoride increases bone mineral content of osteoporotic vertebrae. Presented at the 68th Annual Meeting of the Endocrine Society, Anaheim, California, June 25, 1986, program p 23.

19.Singer, F.R., Sharp, C.F., Jr. and Rude, R.K.: Effect of Sodium fluoride treatment on vertebral bone mineral content in osteoporotic patients. Parathyroid Conference, Nice, France, 1986.

20.Kirk, S., Sharp, C.F., Jr., Elbaum, N., Simons, S.M., Mohler, J.G. and Rude, R.K.: Effects of running on bone mass in women. Clin Res 188A, 1987.

21.Gruber, H.E., Stover, S. Sharp, C.F., Jr. and Marshall, G.J.: Depletion of bone mineral content post-lactation: Events dependent on dietary calcium content in the rat. Program of the Ninth Annual Meeting of the American Society for Bone Mineral Research, June 1987.

22.Endres, D.B., Villanueva, R., Sharp, C.F., Jr. and Singer, F.R.: Suppressed Intact and Normal Total Immunoreactive Parathyroid Hormone in Hypercalcemia Associated with Malignancy. Presented at the 71st Annual Meeting of the Endocrine Society, June 1989. Program, p. 470.

23.Gruber, H.E., Sharp, C.F., Jr., Rude, R.K., Ryzen, E., Adams, J.S. and Singer, F.R.: Efficacy of 1,25-(OH)2D3 and Phosphorous in Treatment of Adult Acquired osteomalacia. 1989 Program and Abstracts of the Joint Meeting, American Society for Bone and Mineral Research and the International Conference on Calcium Regulating Hormones. Presented in poster form on September 9, 1989.

24.Gruber, H.E., Sharp, C.F., Jr. and Stover., S.: Densitometric Evidence for a Metabolic Memory for Mineral Metabolism in the Rat. Presented at the Thirteenth Annual Meeting of the American Society for Bone and Mineral Research, San Diego, California, August 26, 1991. Program of the ASBMR 1991 Abstract #545.

25.Sharp, C.F., Jr. and Ross, B.D.: Proton Magnetic Spectroscopy of Brain in Primary Hyperparathyroidism. Program of the Fifteenth Annual Meeting of the American Society for Bone and Mineral Research, August, 1993.

26.Sharp, C.F. Jr.: Granulomatous Thyroiditis in a Chernobyl Survivor presenting as

Acute cervical radiculitis. Program of the 99th Annual Meeting of the Endocrine

Society, San Diego, California, March 7, 2015 Abstract #21629

27. Pham, A.H., Sharp, C.F. Jr.: Primary Hyperparathyroidism presenting as

Diffuse Osteolytic Lesions. Program of the 99th Annual Meeting of the Endocrine

Society, San Diego, California, March 7, 2015 Abstract #21640.

28. Le, W., Wang, E.Y., and Sharp, C.F. Jr.: PTHrP-mediated hypercalcemia associated

With benign uterine leiomyoma. Program of the 99th Annual Meeting of the Endocrine Society, San Diego, California, March 6, 2015 Abstract #20218

OTHER

Member, Board of Directors, Huntington Memorial Hospital Jan 2009-Dec 2014

Emeritus Professor of Medicine, Huntington Memorial Hospital 2015-present

2016 Gamble Award, Huntington Memorial Hospital

Nominee, USC Choi Family Awards for Patient-Centered Care

May 1, 2019

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