DR. SANCHAYAN MANDAL D.O.B June **, ****

Permanent: M: 098********/082********

B-6/119, Kalyani, Nadia

West Bengal- 741235, India email: ads44k@r.postjobfree.com Education:

****-** ********* ** National Board (DrNB), Department of Medical Oncology, N.B.E, (National Bard of Examination), Ministry Of Health and Family Welfare New Delhi

2014-17 Diplomate of National Board (DNB), Department of Radiation Oncology

(Radiotherapy and Clinical Oncology) N.B.E (National Board of Examination), Ministry Of Health and Family Welfare. New Delhi

2001-06 Bachelor of Medicine & Bachelor of Surgery (MBBS), Nilratan Sircar Medical College, NRSMCH, (Calcutta University) Kolkata Special Exams, Workshop, Certification:

2020 PROFESSIONAL DIPLOMA IN CLINICAL RESEARCH (PDCR), Catalyst Clinical Service Pvt, Ltd.

2015 ASCO International Palliative Care Workshop and certification

(EPIC&SGCCRI)

2007-08 USMLE STEP1,STEP2 CK,GRE,TOEFL,ECFMG

Clinical Trials (Associate and co investigator):

A Randomised multicentre double blind, phase III study of AZD 9833 ( oral SERD ) plus Palbociclib versus Anastrazole plus Palbocilcib for treatment of patients with Estrogen +, HER2 Negative, Advanced Breast Cancer (ABC) who have not received any systemic treatmewnt for Advanced Disease ( SERENA - 4)

A Phase 2, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Trastuzumab Deruxtecan (T-DXd, DS-8201a) for the Treatment of Selected HER2 Expressing Tumors (DESTINY-PanTumor02) ( Pancreas, Cervix )

A Phase 3, Open-Label, Randomized Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With EGFR-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure (MARIPOSA-2)

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2- Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01).

A Phase 3 Open-label Trial of Neoadjuvant Trastuzumab Deruxtecan (T-DXd) Monotherapy or T-DXd Followed by THP Compared to ddAC-THP in Participants With High-risk HER2-positive Early-stage Breast Cancer (DESTINY-Breast11).

A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter, International Study of Osimertinib as Maintenance Therapy in Patients With Locally Advanced, Unresectable EGFR Mutation-positive Non-Small Cell Lung Cancer (Stage III) Whose Disease Has Not Progressed Following Definitive Platinum-based Chemoradiation Therapy (LAURA).

A Prospective, Open-label, Phase 4 Study to Evaluate the Safety of Pembrolizumab

(KEYTRUDA®) in Subjects with Unresectable or Metastatic Melanoma or PD-L1 positive Non-small Cell Lung Cancer (NSCLC) in India (Keynote-593)

A Phase III, Randomized, Open-Label, Controlled, Multi-Center, Global Study of First- Line Durvalumab in Combination With Standard of Care Chemotherapy and Durvalumab in Combination With Tremelimumab and Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone in Patients With Unresectable Locally Advanced or Metastatic Urothelial Cancer (NILE).

A Phase III, Open-label, Randomized Study of Osimertinib With or Without Platinum Plus Pemetrexed Chemo, as First-line Treatment in Patients With Epidermal Growth Factor Receptor (EGFR) Mutation Positive, Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLAURA2).

A Phase III Randomized Multi-Center Double-Blind Global Study to Determine the Efficacy and Safety of Durvalumab in Combination With and following Chemoradiotherapy Compared to Chemoradiotherapy Alone for Treatment in Women With Locally Advanced Cervical Cancer (CALLA)

A Phase III, Double-Blind, Placebo-Controlled Study of Neoadjuvant Durvalumab + Chemotherapy Followed by Adjuvant Durvalumab for the Treatment of Patients With Resectable Stages II and III non-small-cell Lung Cancer: (AEGEAN Trial)

A Phase III Randomized, Double-Blind, Placebo-Controlled, Multi- Regional, International Study of Durvalumab in Combination with Gemcitabine plus Cisplatin versus Placebo in Combination with Gemcitabine plus Cisplatin for Patients with First- Line Advanced Biliary Tract Cancers (TOPAZ-1)

Clinical /Work Experience

2019-22 DrNB Superspeciality Fellow, Medical Oncology & Hematology, Artemis Hospital, Gurugram, Haryana

2019-19 Senior Resident, Clinical & Radiation Oncology, VMMC & Safdarjung Hospital, New Delhi

2018-19 Senior Resident, Clinical& Radiation Oncology, Delhi State Cancer Institute (DSCI), New Delhi

2017-18 Senior Resident at Department of Radiotherapy and clinical Oncology, S.G.C.C.R.I, Kolkata

2014-17 DNB Clinical Oncology & Radiotherapy resident at SGCCRI, Thakurpukur, Kolkata

2010-14 Critical Care Medical Officer : Columbia Asia Hospital, Kolkata, Kalyani Millennium Nursing home, Kalyani, Health Care Nursing Home, Kalyani

2007 House Job ship, Department of Medicine, SSKM Hospital, Kolkata

(Feb’07 to April’07)

Fellowships in U.S.A

Department of Cardiology & Critical Care, Texas Heart Institute, St.Luke Hospital, Houston, Texas, U.S.A under Dr.Biswajit Kar (August’08 to September’08).

Department of General Surgery, University of Texas Medical School, Houston, Texas, U.S.A under Dr.Richard Andrassy (August’08 to September ’08).

Department of Cardiothoracic Surgery, Baylor College of Medicine, Houston, Texas, U.S.A under Dr.Jimmy.Howell, and Dr.H.H.Whisennand, (June’08 to July’08).

Department of Cardiovascular Surgery, Methodist Hospital, Houston, Texas, U.S.A under Dr.Eric.K.Peden and Dr.Joseph Naoum, (May ’08 to June’08). Conference/Seminar/CME:

2017 Orally Presented abstract at AROI,W.B Chapter’ An Prospective Observational Study of clinical response and early toxicities of early glottic cancer in patients treated with Simulator based Conventional Telecobalt Radiotherapy v/s 3 Dimensional Conformal Radiation Therapy

2015 ICRO Teaching course “Management of Brain Tumors”, R.R. Cancer Institute, Bareilly

2015 ‘Controversies in Clinical Oncology 2015’by T.M.C,Kolkata

2014 AROICON (Association of Radiation Oncologists of India) Conference 2014 at Imphal, Manipur & ICRO.

Members& Awards:

2022 EMO Member 471660

2017 Won First Prize in AROI Conference Quiz Contest, 2017 February

2015 Life Member of AROI, LM 2170

Publications:

2019 Sanchayan Mandal et al. Prospective Observational Comparative Study of Response and Toxicities in Early Glottic cancer Using Telecobalt Versus 3DCRT. Indian Journal of Otolaryngology and Head & Neck Surgery; 2019,August. ISSN 2231- 3796; DOI.https://doi.org/10.1007/s12070-019-01729-4

2015 Sanchayan Mandal et al.. Choroidal melanoma of left eye with very early liver metastasis. J Can Res Ther 2015;11:957-60.

2015 Sanchayan Mandal et. al. A Case of Multiple Myeloma Presenting with Plasmacytoma of Body of Sphenoid Bone: A Case Report. J Clin Exp Oncol 2015, 4:3.

2015 Sanchayan Mandal et. al. Squamous Cell Carcinoma of Lung with Skull Metastasis: A Case Report. Journal of Pulmonary & Respiratory Medicine. https://www.omicsonline.org/open-access/squamous-cell-carcinoma-of-lung-with-skull- metastasis-a-case-report-2161-105X-1000292.php?aid=63401.

2009 Preeti Tyagi, Maloy B. Mandal, Sanchayan Mandal, Shashikant C.U. Patne, A.N. Gangopadhyay . Pouch colon associated with anorectal malformations contractions fail to show spontaneous contractions, but responds to acetylcholine and histamine in vitro. . J Pediatr Surg. 2009 Nov; 44(11):2156-62

2009 Maloy B Mandal, Manoj K Sahu, Sanchayan Mandal, P K Gupta. In vivo and in vitro bradycardia induced by local anesthetics is potentiated by calcium channel blockers.Indian J Physiol Pharmacol 2009; 53(2) Research Experience:

2009 Research Assistantship, Department of Physiology, Banaras Hindu University (BHU), Varanasi, India (October’08-July’09)

2006 Study of incidence and prevalence of hypertension and risk factors determination in adolescent school going children of Kolkata, India, at Nil Ratan Sircar Medical College & Hospital, Kolkata, India

2006 Study to assess the awareness & practice of universal health precautions as well as the incidence of blood-borne infections due to work related injuries among the health professionals at Nil Ratan Sircar Medical College & Hospital, Kolkata, India.

2005 Study to assess and compare the influence of socio-economic and environmental conditions on the health of a family unit as well as to determine the nutritional and immunization status of under-five children in both urban and rural areas at Nil Ratan Sircar Medical College & Hospital, Kolkata, India. Voluntary Organizational Experience:

2007 Charitable Dispensary of Indian Red Cross society, Kalyani Branch, W.B, India (02/2007 to 02/2008) including the outdoor activities on Health & Hygiene such as Blood group determination, routine health checkups, well child exams and attending outpatient clinics.

1999 Trainer in local swimming club”Kalyani Town Club” (05/1999 to 08/1999)

Personal Skills and Competences:

Computer skills: MS Word, Excel, Power point, Sigma plot 8.0 and Sigma stat, Lab Chart 6Pro, Lab Chart 5 pro; Operational knowledge of SPSS analysis packages, C programming, basic HTML, JavaScript skills

Recreational activities: guitar playing, Cricket, Football, Swimming, Sketching, Stamp collection, listening music, watching movies, cooking, and singing.

Fluent in written and spoken English

Excellent references furnished on request

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