CURRICULUM VITAE

Dr. HANMANTH REDDY VULUPALA

Plot No 56, Sagar enclave, Sagarring road, Bairamalguda, Hyderabad-500079 Mobile: +91-995*******,

E-mail: adr4kz@r.postjobfree.com

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Career Objective

To pursue an active research career in organic chemistry where i can utilize the experience and training in organic synthesis and contribute my best for the development of science and the organization.

Academic Qualifications

March 2009 – June 2015 Ph. D. in Synthetic Organic Chemistry Research Supervisor: Dr. Lingaiah Nagarapu

Thesis Title: “A Novel Diversified Methods for the Synthesis of 2-Hydroxy Indanone Templates and Total Synthesis of Galantinic acid and Xestoaminol-C”.

CSIR - Indian Institute of Chemical Technology, Hyd. July 2006 - May 2008 Master of Science in Organic Chemistry Osmania University,

Hyderabad, India.

July 2002 - May 2005 Bachelor of Science

Osmania University,

Hyderabad, India.

Research Experience

Associate scientist III at Sai life sciences, Hyderabad, December 2020- Present. Presently we are working multiple projects.

Associate scientist II at Chemveda life sciences, Hyderabad, November 2018- November 2020. During this period, i have worked for multiple projects. In this period, i maintained small team, weekly work updates, LNBs and ELNBs.

Postdoctoral Research Associate, at Academia Sinica, Taipei, Taiwan from May 2016-December 2017. Under the Supervision of Prof. Dr. Chung Yi Wu, I have completed the Synthesis of various structural units of the capsular polysaccharide of streptococcus pneumoniae serotypes 6A, 6B, 6C and 6D.

As part of my PhD project, I have successfully synthesized biologically active molecules like Galantinic acid, Xestoaminol C, 2-(hydroxymethyl)-7,8-dihydro- 1H- indeno[5, 4-b] furan-6 (2H)-one and it’s analogues.

Experienced in handling moisture sensitive reactions and reagents.

Well versed in handling the enzymatic resolution reactions of alcohols with various enzymes.

Exceptional experimental and theoretical knowledge in carbohydrate chemistry. Research skills

1. Creating the proper network of reactions to achieve target complex molecules from readily available simple starting materials.

2. Developing the tools, i.e., the reactions and reagents. Ability to produce independent research outputs of high quality.

3. Expertise in writing research proposals.

4. Expertise in analyzing spectroscopic data like NMR, Mass, IR etc. 5. Profound efficiency in handling of hygroscopic, air sensitive reagents and reactions. 6. Good knowledge of the computing and software: Microsoft Office, ISIS Draw, Chemoffice, Sci-Finder, Reaxys, ISI-Web of Knowledge and Scopus. 7. Experienced in handling the IR instrument for functional group identification. 8. Capable of collaborative and independent work.

Research Interest

Development of new methodologies and application in total synthesis of natural products.

Total Synthesis of natural product molecules.

Asymmetric synthesis (metal and organocatalysis)

Drug design and development.

Development of New Organic Transformations by Organometallic Compounds. Awards and Fellowships

Awarded Senior Research Fellowship (SRF) by the Council of Scientific and Industrial Research (CSIR) from April 2011-March 2014.

Awarded Junior Research Fellowship (JRF) by the Council of Scientific and Industrial Research (CSIR) from March 2009 - March 2011.

Publications:

1. Molecular Iodine–Catalyzed Synthesis of 1,2,3,6-Tetrahydropyrimidines. Lingaiah Nagarapu, Hanmanth Reddy Vulupala, Ch.Venkatanarsimhaji, Rajashaker Bantu & Ramakrishna Reddy. A. Synthetic comm., 2012, 42, 2131-38. 2. Efficient synthesis and resolution of novel 2-(hydroxymethyl)-7,8-dihydro-1H- indeno[5, 4-b] furan-6 (2H)-one by lipase Pseudomonas cepacia. Lingaiah Nagarapu, Hanmanth Reddy Vulupala, Rajashaker Bantu, Yashodakrishna Sajja, Jagadeesh Babu Nanubolu. Tetrahedron: Asymmetry, 25, 2014, 578-82. 3. Total synthesis of Xestoaminol-C from D-Glucose. Hanmanth Reddy Vulupala, Yashodakrishna Sajja, Rajashekar Bantu, Lingaiah Nagarapu. Current Organic Chemistry, 19, 2015, 2040-2045. 4. Three-component, one-pot synthesis of benzo[6,7]cyclohepta[1,2-b] pyridine derivatives under catalyst free conditions and evaluation of their anti-inflammatory activity Yasodakrishna Sajja, Hanmanth Reddy Vulupala, Rajashaker Bantu, Lingaiah Nagarapu, Sathish Babu Vasamsetti, Srigiridhar Kotamraju, Jagadeesh Babu Nanubolu. Bioorg. Med. Chem. Lett., 26, 2016, 858–863.

5. A convenient synthesis and screening of benzosuberone bearing 1,2,3-triazoles against Mycobacterium tuberculosis

Yasodakrishna Sajja, Sowmya Vonguru, Lavanya Jilla, Hanmanth Reddy Vulupala, Rajashaker Bantu, Perumal Yogeswari, Dharmarajan Sriram, Lingaiah Nagarapu. Bioorg. Med. Chem. Lett., 26, 2016, 4292-4295.

6. Design, synthesis, and in vitro antituberculosis activity of benzo[6,7]cyclohepta[1,2- b]pyridine-1,3,4-oxadiazole derivatives

Yasodakrishna Sajja, Sowmya Vanguru, Hanmanth Reddy Vulupala, Lingaiah Nagarapu, Yogeswari Perumal, Dharmarajan Sriram, Jagadeesh Babu Nanubolu. Chemical Biology & Drug Design, 2017, 1-5.

7. Design, synthesis and in vitro anti-tuberculosis activity of benzo [6,7]cyclohepta[1,2- b]pyridine-1,2,3-triazole derivatives

Yasodakrishna Sajja, Sowmya Vanguru, Hanmanth Reddy Vulupala, Rajashaker Bantu, Perumal Yogeswari, Dharmarajan Sriram, Lingaiah Nagarapu. Bioorg. Med. Chem. Lett., 27, 2017, 5119-5121.

8. Ceric ammonium nitrate (CAN)-catalyzed, efficient, one-pot, three-component, aza- diels-alder reactions for a facile synthesis of tetrahydropyranoquinoline derivatives. Ravinder Goud Puligoundla, Hanmanth Reddy Vulupala, Nagaiah Kommu & Sudhakar Babu Kondra. Synthetic comm., 2015, 45, 504-512.

9. Potent ACE inhibitors from 5-hydroxy indanone derivatives. Hanmanth Reddy Vulupala, Yasodakrishna Sajja, Pankaj K. Bagul, Raviteja Bandla, Lingaiah Nagarapu, Sanjay K. Benerjee. Bioorganic Chemistry, 77, 2018, 660–665. 10. Synthetic Library of Oligosaccharides Derived from the Capsular Polysaccharide of Streptococcus pneumoniae Serotypes 6A and 6B and Their Immunological Studies. Ravinder Mettu, Yu-Hsuan Lih, Hanmanth Reddy Vulupala, Chiang-Yun Chen, Mei-Hua Hsu, Hong-Jay Lo, Kuo-Shiang Liao, Yang-Yu Cheng, Cheng-Hsun Chiu and Chung-Yi Wu. ACS Infect. Dis. 2022, 8, 3, 626–634.

Conference and Symposiums

Organic synthesis and human well-being: Emerging opportunities and challenges.

[OSHWB-2010], held at IICT, Hyderabad, India on August 1-4, 2010.

National seminar on “New Dimensions in Chemical Sciences” [NDCS-2010], held at Osmania University, Hyderabad, India on January 30th, 2010.

International Symposium on “Chemistry and Chemical Biology of Natural Products.

[CCBNP-2012], held at IICT, Hyderabad, India on August 2-4, 2012.

Innovations in Science and Technology for Emerging Knowledge Society. (A.P.Science Congress -2013), held at Hyderabad Central University, Hyderabad, India, November 14- 16, 2013.

International Symposium on “Nature Inspired Initiatives in Chemical Trends” [NIICT- 2014], held at IICT, Hyderabad, India on March 2-5, 2014.

101st Indian Science Congress [ISC-101] Seminar participation, held at University of Jammu, Jammu Kashmir, India on February 3-7, 2014. Personal Details

Date of Birth : 15th Feb 1985

Nationality : Indian

Gender : Male

Marital status : Married

References

1. Dr. Lingaiah. Nagarapu

Principal Scientist, Crop Protection Chemicals Division, CSIR-Indian Institute of Chemical Technology, Hyderabad-500007 Telangana, India.

E-mail: adr4kz@r.postjobfree.com

Mobile no: +91-986*******

2. Dr. B.V. Subba Reddy FNASc,

Head of Semiochemicals & Crop Protection Chemicals Divisions, CSIR-Indian Institute of Chemical Technology, Hyderabad-500 007 Telangana, India.

E-mail: adr4kz@r.postjobfree.com

Mobile no: +91-994*******

3. Dr. Chung Yi Wu

Research Fellow and TBF Chair in Biotechnology,

The Genomics Research Center, Academia Sinica

128 Academia Road, Sec. 2, Nankang, Taipei, 115

Taiwan, ROC

Email: adr4kz@r.postjobfree.com

Telephone: +886-*-****-****

Declaration

I declare that all the above information disclosed by me is true to the best of my knowledge.

(Dr. Hanmanth Reddy Vulupala)

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