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Quality Analyst Chester

Location:
Winston-Salem, NC, 27106
Salary:
80000-100000
Posted:
July 25, 2021

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Resume:

Summary

Detail-oriented chemistry scientist with expertise in the field of Analytical and Medicinal Chemistry and passionate about research and development & quality control positions. Extensive Expertise (13+ years) in interdisciplinary chemical R&D, experimental methodologies either spectroscopic, chromatographic or electrochemical, synthesis, production, formulation, processing, biological and pharmaceutical applications of drugs in different matrices. Adopted proficiency in Good Laboratory Practices, lab maintenance, data collection & analysis, and ICH & FDA guidelines. Green Card Holder based on scientific qualifications and eligible to work in the USA.

Highlights of Qualifications (Technical & Experimental Skills)

Strong knowledge in fundamentals of Analytical, Organic and Medicinal Chemistry.

Excellent hands-on experience in dealing with chromatographic techniques like HPLC, LC/MS and CE beside titration, elemental analysis, UV-Vis spectroscopic and fluorometric techniques using different instruments like Agilent®, Beckman Coulter®, Labomed®, Genesys®, Thermo Scientific®, Genway® and waters®.

Analytical method development and good practice in pharmaceutical analysis (GMP, GLP).

Excellent application of analytical validation parameters such as linearity, precision, accuracy, selectivity, specificity, robustness, ruggedness, LOD, LOQ, system suitability parameters and stability-indicating studies.

Adopted proficiency in organic chemistry including NMR, FTIR, Mass characterization, chemical synthesis, drug design and modeling using MOE software.

Experience in computational chemistry and manipulating the spectra data like Dual-wavelength, Advanced Absorption Subtraction, Ratio Derivative, Ratio Difference, Spectrum Subtraction, Zero Crossing, Area Under Curve, Q-Absorbance, Bivariate and Simultaneous Equation Methods in addition to chemometric analysis.

Proficient in instrument set-up and maintenance, safety training.

Proven record of managing multiple projects with the ability to prioritize multiple competing tasks to achieve project timelines in a fast-paced and stressful work environment while maintaining quality assurance standards and excellent teamwork.

Highly analytical, data-driven, problem-solving, professional communication skills, present/explain complicated information to non-technical audiences, and prepare clear, concise reports, and invention disclosures. Skilled in ChemDraw, MOE, Matlab, for data analysis.

Education:

Ph.D. in Medicinal Chemistry: based on joint supervision program between Wake Forest University, USA and Faculty of Pharmacy, Zagazig University, Egypt. 2012–2016

Master in Medicinal Chemistry: Faculty of Pharmacy, Zagazig University, Egypt. 2008–2011 B.SC. of Pharmaceutical Sciences (Honours): Faculty of Pharmacy, Zagazig University, Egypt.2002–2007

Professional Experience Highlights:

Postdoctoral researcher: University of Chester, UK. 2019–2020

-Accomplishments (12 peer-reviewed journal articles in the field of spectrophotometry and HPLC techniques)

- Led research to design novel, highly emissive dyes for detection of COVID-19 spike proteins.

- Led research to design new compounds with anti-cancer activities.

Head of Bioequivalence and Accurate Measurement Unit, Faculty of Pharmacy, Zagazig University, Egypt. 2016-2019

- Supervised 5 analytical projects for postgraduate researchers in the field of HPLC and UV-Vis spectrophotometry (20 peer-reviewed journal articles).

-Performed pharmacokinetic and toxicological studies for certain co-administered in rat plasma using LC/MS (3 peer-reviewed journal articles).

-Led research to determine certain drugs and their metabolites in human serum for undergraduate students (one peer-reviewed journal article).

-Certified Instrumental Analysis Trainer: HPLC and spectrophotometry.

Ph.D. visiting scholar: Department of Chemistry, Wake Forest University, NC, USA. 2013–2015

-Supervised analytical projects for undergraduate students in the field of graphene quantum dots and squarylium dyes.

-Led research to analyze spectral characters of some boronic acid-based squarylium dyes and their applications in pharmaceutical and biological fields either using fluorimetry or capillary electrophoresis techniques (5 peer-reviewed journal articles).

PROFESSIONAL and PERSONAL DEVELOPMENT:

-Participation in 12 scientific conferences: 1 in the USA and 11 in Egypt.

-Completed Thornton Science Park (TSP) Site Induction Course at University of Chester, England (16 December 2019).

-Completed LC-MS Method Validation Course Program at the University of Tartu, Estonia (26 November 2019 -7 February 2020).

-Completed Remote Material Control and Accountability course for the Pharmaceutical Sector (Components of a Chemical Inventory Management System and CMS, CRDF Global, USA (7 July 2021).

-Programs Attended at the Faculty and Leadership Development Center, Zagazig University.

1. Ethics for Scientific Research Program (21-23 August 2010).

2. Effective Presentation Skills Program (24-26 August 2010).

3. Competitive Local and International Research Projects Program (28-30 August 2010).

4. Communication Skills in Different Types of Education Program (31 August - 2 September 2010).

5. International Scientific Publishing Program (4-6 September 2010).

6. Fulfillment of the Quality Assurance Criteria (2 October 2010).

7. Accreditation Standards: Practices and Indicators for Self-Study Preparation (2 September 2019).

8. Strategic Planning Program (21-26 September 2020).

9. Research Team Management Program (25-28 September 2020).

10. Using Technology in Teaching Program (29 September - 2 October 2020).

11. E-Learning Program (6-9 October 2020).

12. Effective Teaching and Learning Strategies for Institutes of Higher Education Program (4-5 November 2020).

Selected Publications:

-Fatma Ibrahim, Mohamed S. Elgawish, Eman Mehanna, Sobhy M. El-Adl, Mohamed M. Baraka, Samy M. Ibrahim, Mahmoud M. sebaiy. Toxicity Profile and Pharmacokinetic Study of Antibiotic Mixtures, Gentamicin and Vancomycin, in rat plasma by Eco-friendly Liquid Chromatography coupled Tandem Mass Spectrometry. Chem. Res. Toxicol. 33 (10): 2647-2658 (2020). https://doi.org/10.1021/acs.chemrestox.0c00285

-Mohsen M. Zareh, Monir Z. Saad, Wafaa S. Hassan, Mostafa E. Elhennawy, Moustafa K. Soltan, Mahmoud M. Sebaiy. Grаdiеnt HPLC Mеthоd fоr Simultаnеоus Dеtеrminаtiоn оf Еight Sаrtаn аnd Stаtin Drugs in Thеir Purе аnd Dоsаgе Fоrms. Pharmaceuticals. 13(2): 32 (2020). doi:10.3390/ph13020032

-Mahmoud M. Sebaiy, Sobhy M. El-Adl, Amr A. Mattar. Different techniques for overlapped UV spectra resolution of some co-administered drugs with paracetamol in their combined pharmaceutical dosage forms. Spectrochim. Acta A Mol. Biomol. Spectrosc. 224: 117429 (2020). https://doi.org/10.1016/j.saa.2019.117429

-Kazuki Ouchi, Christa L. Colyer, Mahmoud Sebaiy, Jin Zhou, Takeshi Maeda, Hiroyuki Nakazumi, Masami Shibukawa, Shingo Saito. Molecular Design of Boronic Acid-Functionalized Squarylium Cyanine Dyes for Multiple Discriminant Analysis of Sialic Acid in Biological Samples: Selectivity toward Monosaccharides Controlled by Different Alkyl Side Chain Lengths. Anal. Chem. 87: 1933−1940 (2015). https://doi.org/10.3390/chromatography3010001

-More publications can be accessed at https://scholar.google.com/citations?user=Rr4BR1kAAAAJ&hl=en

HPLC, GC, UV, ICP-MS, FTIR, TOC, CE, ICE, Karl Fisher, Plate Reader SDS-PAGE, western blotting, IEF, ELISA, PCR, cGM, QC experience, spectrophotometer, Reviewing assays, Equipment Calibration, Writing Quality Records, UV-Vis, PNP, Osmolarity, PCR & CE, pH, Conductivity,



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