Dr. ANKUR A. KANERIA

***, ***** *********,

Near Pleasure club, Opp. Jain nagar Society, Ghuma, Ahmedabad-380058, Gujarat

E-mail: adnjfo@r.postjobfree.com

Mob: +918*********, +919*********

Profile:

Deputy Manager, Synthetic Development Lab (API Division) in Cadila Pharmaceuticals Ltd having 11 years and 6 months of experience.

Educational Qualification:

Ph.D (Organic Chemistry) (2018) Saurashtra University, Rajkot

M.Sc. (Organic Chemistry) with 66.0% (2008) Saurashtra University, Rajkot

B.Sc. (Chemistry) with 72.0% (2006) from Saurashtra University, Rajkot.

Experience (11 years and 2 months):

1)Name of Company : Cadila Pharmaceuticals Limited (API R&D)

Location : Dholka, Ahmedabad

Designation : Deputy Manager (Synthesis)

Duration : Since Jul’19

To lead a separate project (API) and delivered with time line and with targeted cost.

2)Name of Company : Raks Pharma Pvt. Ltd. (API R&D)

(Division of Amneal Pharmaceutical Pvt. Ltd.)

Location : Ahmedabad

Designation : Asst. Manager (Synthesis)

Duration : Aug’10 to Jul’19

Job Description:

To lead a separate project (API) along with team and delivered with time line.

Proven skills in handling multiple API projects for synthetic development & transfer of the same at plant level for commercialization.

Synthetic route designs, CQA, CMA and CPP identification for process development of API and transformed lab process to commercial scale.

Documentation, Technology transfer and scale up of API at pilot plant and commercial plant.

Preparation of process development report, structure elucidation report of API/Intermediates/KSM

Identification, characterization and synthesis of process related or degradation impurities based on CMC

Trouble shooting and cost reduction of various commercialized API.

Handled day-to-day planning and guided junior team members on effective synthesis and routine lab work.

Control of GENOTOXIC impurities (GTI) during the process development is challenged now a day, to identify GTI impurities and control it as per ICH M7 (R1) guideline.

Conversant with synthetic process development of API’s across various therapeutic categories like

Antidiabetis : Dapagliflozin (Novel route).

Serotonin–norepinephrine reuptake inhibitor (SNRI)(MDD):Milnacipran hydrochloride (Novel route) and Levomilnacipran Hydrochloride (Novel route)

Anticancer : Tipiracil Hydrochoride (Novel route)

Antiplatelet : Clopidogrel bisulfate

Also working in DMF deficiency of Rabeprazole sodium and Divalproex sodium

Also working on Valbenazine Tosylate project as project leader.

3)Name of Company : Oxygen Healthcare Pvt. Ltd. (CRO)

Location : Ahmedabad

Designation : Research associate (Synthesis)

Duration : Oct’09-Aug’10

Job Description:

Synthesis of target compounds

Purification of synthesized compound by different purification techniques

Identification of compound by mass, 1H NMR and 13C NMR

4)Name of Company : Sam Fine Chem Pvt. Ltd. (Intermidiate)

Location : Rajkot

Designation : Research Scientist (R&D)

Duration : Aug’08-Oct’09

Computer knowledge:

M.S.OFFICE

Patent and literature search

Chem sketch and chem draw

SciFinder and Reaxys search

Practical skill:

API Process development

Cost reduction

Impurity Synthesis as per CMC

Process optimization

Plant trouble shooting

Project planning and execution

Regulatory knowledge

Novel route scouting

Technology transfer

Interpretation of Mass, 1H NMR and 13C NMR spectral data, HPLC & GC graph, XRPD

Documentation:

Process development reports

Structure elucidation reports

Specification of KSM, Intermediate & API

Drug license

Daily Experiment summary and comparisons of data

Technical package

Costing Sheet

Patent and publications:

1.Process for the preparation of Dapagliflozin and its intermediates thereof.

Application No. WO2018/029264A1

2.Crystalline form of Ticagrelor

Application No. WO2017118633A1

3.Process for the preparation of Tipiracil hydrochloride

Application No. WO2019002407A1

4.Synthesis, Characterization & Biological evaluation of carbazide and semicarbazide analogue of Pyrrolizine. Chemistry & Biology Interface, 2016, Vol.6, 109-117.

5.Synthesis, Characterization and Antimicrobial Activities of some Novel 3-(4-Bromobenzyl)-5-(Thiophen-2-yl)-4H-1,2,4-Triazol Derivatives. International Letters of Chemistry, Physics and Astronomy, 2016, 68, 10-17.

6.Synthesis, Characterisation and Antimicrobial Activity Studies of Some New N-Substituted Piperidine Derivatives of 2-(4-chloro-4-(4 chlorophenyl)) Piperidine. J. Chem. Pharm. Res., 2017, 9(5):348-353.

Personal:

Full name : Ankur A. Kaneria

Date of Birth : 11th April 1986

Declaration:

I hereby declare that the information furnished above is true to the best of my knowledge.

YOUR’S FAITHFULLY

ANKUR A. KANERIA

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