Rutuja Rajeev Patil

Southfield, MI • 646-***-**** • adkted@r.postjobfree.com • linkedin.com/in/rutuja-patil-1 READY TO RELOCATE

OBJECTIVE

I intend to pursue knowledge and contribute to the field of drug discovery in an organization that strives for the betterment of human health.

EDUCATION

2020-Present Wayne State University School of Medicine Detroit, USA MS in Biochemistry and Molecular Biology

GPA: 3.8

2015-2017 Bharati Vidyapeeth’s Poona College of Pharmacy Pune, India Master of Pharmacy; Major in Pharmaceutical Biotechnology GPA: 3.9

2011-2015 Shivaji University Kolhapur, India

Bachelor of Pharmacy, Major in Pharmaceutical Sciences GPA: 3.5

PROFESSIONAL SKILLS

• Drug interaction using molecular docking and its use in new drug discovery, Bioinformatics tools (MEGA, Blast, ExPasy, NCBI bioinformatics tools, Marvin sketch, and Marvin view, Machine learning basics, etc)

• Molecular docking and modeling (Schrodinger Maestro, Autodock, Autodockvina, Discovery Studio Software, Swiss Model and visualization tools like PYMOL, JMOL)

• Isolation of DNA (Animal Tissue, Bacteria), Agarose Gel Electrophoresis, Handling of Bacterial cultures, Restriction Digestion and Transformation, Biochemical and cell line assays, PCR, qPCR

• Research and review writing, oral scientific presentations, and scientific discussions

• Microsoft Office (Word, Excel, Powerpoint)

EXPERIENCE

June 2018- October 2019 Interdisciplinary Science and Technology Research Academy (ISTRA) Pune, India Internship Trainee

• Performed molecular modeling of Curcumin, Difluorinated-curcumin (CDF), and DiFiD using targets such as IL- 1β, TGF-β, MMP-2, MMP-9 and DCLK.

• Studied the expression of IL-1β, PGE2, and TGF-β on the treatment of DiFiD analogs by real-time quantitative polymerase chain reaction (RTqPCR) in human synoviocytes

• Determined the cell viability of analogs for SW-982 cell line

• Performed the nitric oxide assay to study the inflammation-induced due to IL-1β treatment

• Performed gene assays using IL-1β, PGE2, and TGF-β genes that revealed the effectiveness of compounds in the treatment of cancer and osteoarthritis.

August 2017- May 2018 Interactive Research School for Health Affairs (IRSHA) Pune, India Project Assistant

• Worked on an Industrial project of Tata Chemicals Ltd. in the Osteoarthritis lab

• Studied various patented molecules for their anti-osteoarthritic potential using cell line study and gene assay and it was found that all the compounds had various degrees of potential (individual or in combination). August 2016- August 2017

Project Intern

• Worked on a full-fledged project titled “Crosstalk of TNF-α and TNAP gene and its modulation by guggul extract in HepG2 cells”.

• Calculated cell viability dose of TNF-α for HepG2 cell line, studied the possible correlation of TNF-α and TNAP in OA, using cell model and assessed the effect of Guggulsterone treatment on the modulation of TNF-α and TNAP and established the evidence for its anti-arthritic potential using qPCR. Association Project: “Formulation, development, and optimization of solid lipid nanoparticles (SLNs) containing an antihypertensive drug- Ramipril”

• Manufactured Ramipril loaded SLNs were prepared and performed characterization studies like drug entrapment efficiency, particle size, zeta potential, FTIR, X-ray diffraction, Scanning electron microscopy, H1 NMR spectroscopy, in vitro drug release, and stability studies Review Manuscripts: 1. Recent advances in the chemotherapy of cancer and special emphasis on the application of genetics in the treatment of cancer”

2. Anticancer properties of Lawsone

HONORS AND AWARDS:

• Graduate Award Dean, WSU, Fall 2020

• Outstanding Student Award, Shivaji University, 2015

• Leadership: General Secretary of College, Shivaji University, 2013-14 OTHER:

• Volunteering:

1. National Service Scheme, Govt of India N.S.S. Volunteer, 2013-2015. 2. Rajarambapu College of Pharmacy, Kasegaon, Maharashtra Member of Student Council, Sept 2011 to May 2015

General Secretary, July 2013 to July 2014

3. Jayant Poverty Eradication Campaign Student Volunteer, June 2011 to Present 4. T. B. Lulla Charitable Foundation Student Volunteer, June 2015 till date.

Contact this candidate