Medical Care

EDUCATION:

Medical School and Internship

****-**** *.*.*.S, Maulana Azad Medical College, University of Delhi, Delhi, India

Residencies and Fellowships

****-**** *.*. **********, Safdurjung Hospital, University of Delhi, Delhi, India

2005-2008 Pediatric Residency, University at Buffalo, Buffalo, NY

2008-2011 Pediatric Endocrinology Fellowship, University at Buffalo, Buffalo, NY

2011-2012 Pediatric Endocrinology Academic Research fellowship, Women and Children’s Hospital of Buffalo

BOARDS & CERTIFICATIONS:

Mar 1999 M.B.B.S, University of Delhi, India

Feb 2002 M.D. Pediatrics, University of Delhi, India

Oct 2002 Diplomate of National Board (Peds), India

Oct 2008 Diplomate of the American Board of Pediatrics-Pediatrics

Nov 2011 Diplomate of the American Board of Pediatrics- Pediatric Endocrinology

Mar 2017 Diplomate in Obesity Medicine

Professional Memberships

2014- present American Diabetes Association

2009-present The Endocrine Society

2009-present Pediatric Endocrine Society

2005-present American Academy of Pediatrics

2001-present Indian Academy of Pediatrics

Medical License

Full License: State of New York

AWARDS & HONORS:

Jun 2011 Endocrine Society - Clinical Fellows Travel Grants at ENDO 2011

Apr 2011 Pediatric Endocrine Society- Travel Grant

Mar 2011 Eastern Society for Pediatric Research Trainee Travel Award

Jun 2010 Endocrine Society - Clinical Fellows Travel Grants at ENDO 2010

Jun 2010 Endocrine Trainee Day - Class of 2010 at ENDO 2010

Apr 2010 Thomas F. Frawley, M.D., Residency Research Fellowship, Honorable Mention; University at Buffalo

Sep 2009 LWPES/ESPE 8th Joint Meeting- Travel Grant

Feb 2001 Dr. Satya Gupta Award; Best Original Research, Indian Academy of Pediatrics

PROFESSIONAL APPOINTMENTS:

ACADEMIC

Aug2018- Present

Clinical Associate Professor of Pediatrics

Department of Pediatrics, Division of Endocrinology and Diabetes Center

John R. Oishei Children’s Hospital &

University at Buffalo, State University of New York, Buffalo, NY

Aug 2012-Aug2018

Clinical Assistant Professor of Pediatrics, Department of Pediatrics,

Division of Endocrinology and Diabetes Center

John R Oishei Children’s Hospital &

University at Buffalo, State University of New York, Buffalo, NY

NON-ACADEMIC

Dec 2014-present Medical Director, Children’s Healthy Weigh of Buffalo

John R Oishei Children’s Hospital, Buffalo, NY

Dec 2012-present

Program Coordinator for American Diabetes Association Education Recognition Program Diabetes Center, John R Oishei Children’s Hospital, Buffalo, NY

Nov 2012-present

Medical Staff, Kaleida Health, John R Oishei Children’s Hospital

May2002- May2005

Registrar (Equivalent to Hospitalist), Pediatrics, Sir Ganga Ram Hospital, New Delhi, India

CLINICAL EXPERIENCE

Present Appointment

Aug2018- Present

Clinical Associate Professor of Pediatrics

Department of Pediatrics, Division of Endocrinology and Diabetes Center

John R. Oishei Children’s Hospital &

University at Buffalo, State University of New York, Buffalo, NY

I am board certified in pediatric endocrinology and diabetes. As a pediatric endocrinologist, I manage children and adolescents, both as inpatients and outpatients, with various endocrinological and metabolic disorders. I am particularly involved in the care of youths with juvenile diabetes, obesity, metabolic syndrome, calcium and bone disorders, abnormalities of growth and puberty, and disorders of sex development.

I am significantly involved in the care of youth with abnormal weight gain and insulin resistance, which was also the focus of my research in fellowship.

I was integrally involved in the development of the diabetes self-care management education program at the Diabetes Center of the Women and Children’s Hospital of Buffalo. Subsequently, our center was recognized by the American Diabetes Association (ADA) for the Education Recognition Program. I am the Program Coordinator at the Diabetes Center of the Women and Children’s Hospital of Buffalo (WCHOB) for the program. I supervise the diabetes self-care management education provided by the center’s certified diabetes educators and nutritionists to youth diagnosed with type 1 and type 2 diabetes. Additionally, I coordinate quality improvement projects that are focused on improving diabetes care delivery.

In my role as an American Board of Obesity Medicine certified physician and a pediatric bariatrician, I have worked with the Kaleida Health Foundation and department of Pediatric Surgery at the Women and Children’s Hospital of Buffalo to develop a multi-disciplinary weight management center for the children and adolescents. It is a regional referral center designed to manage youth with obesity and obesity-related co-morbidities. A select population of the youth undergoes bariatric surgery. As the medical director of the center, I am not only responsible for the clinical care but have administrative responsibilities including, but not limited to, coordination of care between the various providers, management of budget, review of the revenue cycles, and evaluation and management of quality of care.

I conduct clinical research and publish on various aspects of general pediatrics and pediatric endocrinology. My current focus is on the prevention of abnormal weight gain in children and adolescents with new-onset type 1 diabetes.

I also mentor UB medical students, pediatric residents, pediatric surgical residents and pediatric endocrine fellows in research on topics related to diabetes and obesity.

Aug 2012- Aug2018

Clinical Assistant Professor of Pediatrics

Department of Pediatrics, Division of Endocrinology/ Diabetes Center

Women and Children’s Hospital of Buffalo &

State University of New York at Buffalo

Buffalo, NY

Previous Appointments

Jul 2011- Jun 2012

Academic Research Fellow

Division of Endocrinology/ Diabetes Center

Women and Children’s Hospital of Buffalo &

State University of New York at Buffalo

Buffalo, NY

Following completion of my ACGME accredited fellowship in Pediatric Endocrinology at the State University of New York, University at Buffalo in June 2011, I worked as an academic research fellow in the same division for another year to enhance my experience in clinical research. During this year, I focused on clinical research in Type 1 Diabetes and Obesity. The preliminary findings of the research were presented at ADA 72nd scientific sessions in the form of a poster and, finalized results were later presented in the Endocrine Society meeting in 2013.

Jul 2008- Jun 2011

Pediatric Endocrinology Fellow

Division of Endocrinology/ Diabetes Center

Women and Children’s Hospital of Buffalo &

State University of New York at Buffalo

Buffalo, NY

The John R Oishei Children’s Hospital (formerly known as the Women and Children's Hospital of Buffalo) is the regional referral center for all pediatric endocrine disorders in Western NY. The various pediatric multi-specialty divisions in the hospital, including the hematology-oncology, genetics, pediatric and neonatal intensive care divisions provide a large referral base for neonates and children with extremely challenging endocrine disorders. Additionally, over 900 children with Type 1 and Type 2 diabetes receive their care at the Diabetes Center.

This created an excellent learning experience, providing me with opportunities to manage neonates, children, and adolescents with a variety of endocrine disorders and diabetes. I additionally volunteer as medical staff at the ADA diabetes camp annually, which has been one of the most valuable experiences that I have gained in the day-to-day care of children with T1DM. Research being an important part of my career, I spent a significant part of my time at the biochemistry laboratory in the University at Buffalo, under the mentorship of Lucy Mastrandrea, MD, PhD, to study new bio-markers for insulin resistance.

Jul 2005-Jun 2008

Pediatric Resident

Department of Pediatrics

Women and Children’s Hospital of Buffalo &

State University of New York at Buffalo

Buffalo, NY

Pediatric residency in a university-based program at a multi-specialty, free-standing Children's hospital was an invaluable experience, which helped me refine my skills as a pediatrician. I was able to pursue research activity during this period which was presented as a poster at a national meeting and was recently accepted for publication in a peer-reviewed journal. The training period helped me realize the importance of pediatric-sub-specialization, not only to provide quality care for children but also for my development as a clinician and a scientist. I found my niche in pediatric endocrinology.

May 2002-May 2005

Pediatric Registrar (equivalent to Hospitalist)

Department of Pediatrics, Center for Child Health,

Sir Ganga Ram Hospital, New Delhi,India

I was responsible for both in-patient and out-patient care of pediatric patients including those in the PICU, and the Liver transplant-ICU. I was directly involved in the post-operative care of pediatric patients following liver transplants. Simultaneously, I was involved in the care of pediatric patients in a 10 bedded PICU.

Additionally, I supported the care of pediatric patients in various sub-specialties including pediatric endocrinology and diabetes. The variety of complex pediatric patients seen at the center provided ample opportunities for clinical research and publications.

May 1999- Apr 2002 Pediatric Resident

Safdarjung Hospital

New Delhi, India

Pediatric residency in one of the busiest hospitals in India set the stage for excellent on-job training in pediatrics. I had many opportunities to manage large numbers of extremely complicated pediatric conditions since Safdarjung hospital is a referral center for patients from all over India. It also provided the logistic support, mentoring, and population base required for clinical research. By the end of my residency, I had not only evolved as a clinician but was also able to publish my research in a peer-reviewed journal.

Jan 1998-Jan 1999 Medical/Surgical Internship

Maulana Azad medical College

New Delhi, India

The rotatory internship is a mandatory part of medical school training where the focus is on the development of clinical experience. I was involved in direct patient care for 1-2 months duration in each of the following specialties - medicine, surgery, obstetrics and gynecology, ENT, ophthalmology, pediatrics, preventive and social medicine.

Administrative Responsibilities:

1. Medical Director of Children’s Healthy Weigh of Buffalo, the multi-disciplinary pediatric and adolescent weight management center at the Women and Children’s Hospital of Buffalo.

2. Program Coordinator for the ADA recognized Diabetes Self Care Management education program for the Diabetes Center at the Women and Children’s Hospital of Buffalo.

PROFESSIONAL ACTIVITIES:

2016, 2019 PLOS One, Journal: Reviewer

2015-present Clinical Pediatrics, Journal Reviewer

2017-2021 International Journal of Environmental Research and Public Health, Journal:

Reviewer

Jan 2015 Endocrine Society: Endo 2015: Abstract Reviewer

2008-2011 Medical Team, American Diabetes Association- Camp Aspire, Rochester, New York

Committee Assignments

2018-present Promotions and Tenure Committee

2017-present Jacobs School of Medicine and Biomedical Sciences, Faculty Council

Representative

2014-present Member, Clinical Competency Committee, Endocrine Fellowship, University at Buffalo.

2012-present Member, Pediatric Residency Recruitment Committee, University at Buffalo.

2012-2015 Member: Teaching Interest Group: Women and Children’s Hospital of Buffalo

Other Activity

Jun 2015-Nov 2016 Member of Pediatric Endocrine Society’s Pediatrician and Practitioner Education Committee: Development of educational material for pediatricians and primary care providers

GRANT / CLINICAL TRIALS:

Current

10/2019- present

Basket Study: Setmelanotide ( RM- 493-014) Phase 2 Treatment Trial in Patients with Rare Genetic Disorders of Obesity.

Sponsor: Rhythm Pharmaceutical

Role: Principal Investigator

5/2012-present

“Type 1 Diabetes TrialNet”

Sponsor NIDDK

Role: Co-investigator

8/2012-present

Type 1 Diabetes Exchange

Sponsor: Jaeb Center (http://www.jaeb.org)

Role: Co-investigator

Completed

8/2017-5/2020 Genetic Testing and Phenotypic Characterization of Severely Obese Pediatric and Adult Volunteers

Sponsor: Rhythm Pharmaceutical

Role: Principal Investigator

4/2017-06/2018 Role of contingency management in the treatment of youth and their

parents in a pediatric tertiary care weight management program

Sponsor: Clinical and Translational Science Institute (CTSI) Pilot Studies Program; Supported by National Center for Advancing Translational Science of National Institute of Health under award number ULTR001412 to University at Buffalo

Role: Principal Investigator

5/2016-5/2018 “A randomized, double-blind, placebo-controlled trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of liraglutide in obese children aged 7 to 11 year(NN8022-4181)

Sponsor: Novo Nordisk

Role: Co-Investigator

2016-9/2018 “A 24 Week, Multicenter, Randomized, Double-Blind, Parallel-Group, Phase 3 Trial with a 28 Week Long Term Safety Extension Phase Evaluating the Safety and Efficacy of Dapagliflozin 10 mg in T2DM Subjects age 10-24 years”

Sponsor: AstraZeneca

Managed through the Pediatric Diabetes Consortium

Role: Co-Investigator

11/2016-11/2018 “Effect of liraglutide for weight management in pubertal adolescent subjects with obesity. A 56-week, double-blind, randomized, parallel-group, placebo-controlled multi-national trial (NN8022-4180)”

Sponsor: Novo Nordisk

Role: Co-Investigator

12/2016-12/2018 “A 6-month, multi-center, randomized, open-label, 2-arm, parallel-group study comparing the efficacy and safety of a new formulation of insulin glargine and Lantus injected once daily in children and adolescents with Type 1 diabetes”

Sponsor: Sanofi

Role: Co-Investigator

1/2017-1/2020 “A Phase 3, double-blind, placebo-controlled, randomized, multi-center study to assess the safety and efficacy of exenatide once weekly in adolescents with Type 2 diabetes and clinical study (D5551C00002)”

PUBLICATIONS:

Refereed Journal Articles

*Trainee

1. Shah, T, Majumdar I, Mastrandrea LM, Quattrin T. Perception of Diabetes Self-Efficacy and Glycemic Control in Youth with Type 1 Diabetes. Diab Spectrum. Accepted for publication Dec2020

2. Lamoshi, A*, Chen, M., Majumdar, I, Harmon CM. Bariatric Surgery in Adolescents. Curr Treat Options Peds May 2020; 6:140–154. https://doi.org/10.1007/s40746-020-00196-2

3. Majumdar I, Espino B*, Bianco K*,Epstein J*, Mamilly L*, Harmon CM. Multi-disciplinary weight management compared to routine care in youth with obesity: what else should be monitored? Endocrine. 2019 Aug; 65(2):263-269

4. Alsaleem M*, Miller D*, Saadeh L*, Majumdar I. Aromatase Deficiency: A Rare Cause of Maternal Virilization and Ambiguous Genitalia in Neonates. BMJ Case Rep. 2019 Jun 16; 12(6). e231267.

5. Cairo SB*, Majumdar I, Pryor A, Posner A, Harmon CM, Rothstein DH; Delivery of Surgical Care Committee of the American Academy of Pediatrics Section on Surgery. Response to Letter to the Editor; Comments on "Challenges in Transition of Care for Pediatric Patients after Weight-Reduction Surgery: a Systematic Review and Recommendations for Comprehensive Care". Obes Surg. 2018 2018 Sep;28(9):2914-2915

6. Cairo SB*, Majumdar I, Pryor A, Posner A, Harmon CM, Rothstein DH; Delivery of Surgical Care Committee of the American Academy of Pediatrics Section on Surgery. Challenges in Transition of Care for Pediatric Patients after Weight-Reduction Surgery: a Systematic Review and Recommendations for Comprehensive Care. Obes Surg. 2018 Apr;28(4):1149-1174

7. Majumdar I, Black TA, Nair J. Hypernatremia management: Focus on etiology. Clin Pediatr. 2018, 57(1): 96-98

8. Majumdar I, Wagner S. Kawasaki Disease Masquerading as Hepatitis: A Diagnostic Challenge for Pediatricians. Clin Pediatr. 2016, 55(1): 73-75.

9. Majumdar I, Bethin K, Quattrin T. Weight trajectory of youth with new-onset type 1 diabetes comparing standard and enhanced dietary education. Endocrine May;2015 (49): 155-62

10. Majumdar I, Mastrandrea LD. Serum sphingolipids and inflammatory mediators in adolescents at risk for metabolic syndrome. Endocrine. 2012 June; 41(3): 442-9

11. Majumdar I, Hartley-McAndrew ME, Weinstock A. Central nervous system Herpes simplex virus infection in afebrile children with seizures. J Child Neurol. 2012 Apr; 27(4):445-50

12. Majumdar I, Mastrandrea LD. Lingual Thyroid as a Cause of Primary Hypothyroidism: Congenital Hypothyroidism in the Neonatal Period and Beyond. Clin Pediatr. 2010 Sep; 49(9):885-8

13. Majumdar I, Sachdev A, Gupta D, Chugh K. To evaluate the impact of initial chest radiograph on final outcome of ventilated patients. Ind J Crit Care Med. 2005; 9 (2): 77-80

14. Majumdar I, Paul P, Talib V.H, Ranga S. The effect of iron therapy on the growth of iron-replete and iron-deplete children. Journal of Tropical Pediatrics. 2003; 49 (2): 84-8

Book chapters

1. Bethin KE, Majumdar I, Muglia LJ. Adrenal insufficiency. In: Pediatric Endocrinology: A Practical Clinical Guide, 3ed. Eds: Radovick S, Misra M. Springer, NY; 2018, pp 285-310

2. Majumdar I, Mazur T. Management of Infants Born with Disorders/Differences of Sex Development. In: Pediatric Endocrinology: A Practical Clinical Guide, 3ed. Eds: Radovick S, Misra M. Springer, NY; 2018, pp 617-640

3. Majumdar I, Mazur T. Management of Infants Born with Disorders of Sex Development. In: Pediatric Endocrinology: A Practical Clinical Guide, 2ed. Eds: Radovick S, McGillivray MH. Springer, NY; 2013, pp 423-440.

4. Majumdar I, Quattrin T. Obesity. In: Succinct Pediatrics: Evaluation and Management for Common and Critical Care. Eds: Feld LG, Mahan JD. American Academy of Pediatrics, Elk Grove Village, IL; 2015. Chapter 38, Obesity; p.415-428.

INVITED PRESENTATIONS:

National/ Regional

Oct 2019 AAP National Conference, New Orleans, LA

-Metabolic Syndrome Seminar

-Endocrine issues in Obesity- When to consult a specialist- Focused Topic

Apr 2018 “Multidisciplinary Approach for Management of Obesity in Youth and Their Families”. The University of Alabama, Birmingham, AL. Pediatric Grand Rounds.

Jul 2016 “Management of Obesity in Youth – A Multidisciplinary Approach in Western NY”. The University of Rochester, Golisano Children’s Hospital, Rochester, NY. Pediatric Grand Rounds.

July 2014 “Diabetes Mellitus- What is new?” South Buffalo Mercy Hospital, Buffalo, NY. Pediatric Grand Rounds.

University at Buffalo and Children’s Hospital of Buffalo

Apr 2016 “Obesity epidemic in youth- What can we do in Western NY?”. Pediatric Grand Rounds.

Aug 2012 “Are children with type 1 diabetes obese: What can we do?” Pediatric Grand Rounds.

Apr 2011 “Association of Serum Sphingolipids and Serum Adipocytokines with Insulin Resistance in Adolescents at Risk for Metabolic Syndrome.”. Pediatric Grand Rounds.

Local Presentations:

Sep2020:

Obesity in youth- it is time to manage it differently. Oishei Children’s Hospital “Healthy U”- Free Community Education Class

May2019 & 2018:

Management of Obesity in Youth-Why is it so challenging and what can be done? Oishei Children’s Hospital “Healthy U– Childhood Obesity” series.

Mar2019:

“Management of Obesity in Youth” for Nurses and Nurse Practitioners in Buffalo Public School-Based Health Program

Media Presentations Offering Professional Expertise:

Podcast: #Charting Pediatrics. podcast on obesity treatment. Nov2019

Television

1. Kaleida Health- Medical Minute Video. Mar2019

2. Medically Speaking Interview. Feb2019

3. WIVB- Channel 4 Buffalo Live Television Interview on Morning Show: March 2015: Obesity epidemic in children

4. Channel 4: Children’s Telethon : Jan 2015: Management of Obesity in youth

Radio

1. Radio Interview: Sep 2016: Kiss 98.5: Discussion on weight management at Children’s Healthy Weigh of Buffalo

2. Radio Interview: Jun 2016: Great Lakes Health Radio: Weight management of youth in WNY.

Newspaper

1. The Buffalo News: Sep 3, 2016: Children’s Hospital program helps kids tackle obesity

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