Medical Assistant

Scott Jafarian Kerman

**** ********* *** *** **** • College Park, MD. 20740

615-***-**** • Email: **********@*****.***

EDUCATION

Vanderbilt Univ. Medical Center – Nashville, TN 2015-2017 Master of Science in Clinical Investigation

Tehran Univ. of Medical Sciences – Tehran, Iran 2005-2013 Doctor of Medicine

PROFESSIONAL WORK EXPERIENCE

Food and Drug Administration – Silver Spring, MD 2019- Present Post-Doctoral Fellow - Center for Drug Evaluation and Research, Office of Clinical Pharmacology, Division of Applied Regulatory Sciences

• Assessing drugs for the risk of Torsade de Point based on CiPA initiative

• Assessing the accuracy of Pupillometry in the setting of opioid agonist/antagonist

• Pharmacokinetic and pharmacodynamic of biosimilars (generic biologic drugs) o Responsibilities included literature review, proposal preparation, providing standard operation of procedures (SOP) documentation, providing statistical analysis plan, medical oversite, research-related clinical consultation, data analysis, manuscript preparation, and internal and external presentations. Vanderbilt University Medical Center – Nashville, TN. 2015 - 2019 Post-Doctoral Fellow - Department of Medicine, Division of Clinical Pharmacology

• Studied the effects of resveratrol supplementation on in-vivo and in-vitro platelet activity via a randomized clinical trial

• Completed a project detailing the contribution of Neuropeptide Y (NPY) to Vasoconstriction and Sympathetic Activation in the Setting of Dipeptidyl Peptidase IV (DPP4) Inhibition. o Responsibilities included literature review, volunteer recruitment, volunteer screening, volunteer admission, monitoring and blood draws, performing study assays, proposal preparation, data analysis, manuscript preparation, internal presentations, and lab work

(platelet aggregation testing, flow cytometry, bifocal microscopic evaluation, western blots, etc.)

Iran University Medical Sciences – Tehran, Iran 2013 - 2015 Research/Clinical Fellow - Department of Medicine, Cardiology Division

• Clinical duties included rounding, attending cardiology clinic, and mentoring medical students

• Projects included B-type natriuretic peptides help in cardioembolic stroke diagnosis and B-type natriuretic peptide and renovascular hypertension

o Responsibilities included case reports, clinical evaluation, literature review, volunteer recruitment, volunteer screening (history taking, physical examination), proposal preparation, data analysis, manuscript preparation and presentation. Scott Jafarian Kerman

9630 Milestone Way Apt 5136 • College Park, MD. 20740 615-***-**** • Email: **********@*****.***

CLINICAL EXPERIENCE

Vanderbilt University Medical Center – Nashville, TN. 2018-2019 Clinical Research hands-on - Department of Medicine, Clinical Research Center o Research subject recruitment, screening (including history taking, physical examinations, and routine lab test evaluation)

o patient admissions for research, monitoring and blood draws (daily work with Epic and RedCap)

Vanderbilt University Medical Center – Nashville, TN. 2016-2018 Clinical Observership (volunteer)

o 2-3 hours/week in cardiology - hypertension clinic – Various attending physicians o limited history taking and physical examination

Bushehr University of Medical Sciences – Dashtestan Province, Bushehr, Iran 2014 - 2015 Village Physician – part time

o Provided comprehensive care to all outpatients – both adult and pediatric populations o Cared for about 7,000 individuals in my jurisdiction Tehran University of Medical Sciences – Tehran, Iran 2011-2013 Medical Intern

o Completed an 18 months internship in internal medicine, pediatrics, and emergency medicine Iranian Red Crescent – Tehran, Iran 2010-2014

Volunteer Medical Assistant & Volunteer Physician

o Responsible for patient care and preventative care education ADDITIONAL RESEARCH EXPERIENCE

• Peer reviewer for numerous journals (2014-present)

• Section editor, Acta Medica Iranica Journal. Tehran, Iran (Remote) (2016-present)

• Member of Research Council of Tehran University of Medical Sciences. Tehran, Iran. (2012-2014)

• Researcher, Head of Students Cardiology Research Community, Scientific Students Research Committee, Tehran, Iran. (2011-2013)

HONORS & RECOGNITION

• Best poster presentation in FDA Clinical Pharmacology Science Week Award (2020)

• VICTR award for research, Vanderbilt university of medical Sciences, Nashville, TN (2017)

• Full scholarship award, Master’s in Clinical Investigation, Vanderbilt (2015)

• Iranian Patent registration, Artificial Lower esophageal sphincter. (2014) Scott Jafarian Kerman

9630 Milestone Way Apt 5136 • College Park, MD. 20740 615-***-**** • Email: **********@*****.***

• Best Student researcher in Tehran University of Medical Sciences of 2012, Awarded for TUMS Research Grant. Tehran, Iran. (2013)

• Best Student Reviewer in 13th National Annual Research Congress of Medical Sciences. Babolsar, Iran. (2012)

• Best Student Workshop, 15th Tabriz International Medical Sciences Conference. Tabriz, Iran. (2012)

• Honored Medical Intern in Burns and Accidents Hospital for excellent sense of responsibility. Tehran, Iran (2012)

• Best Student Reviewer in Annual Research Congress of Eastern Medical Sciences Students, Mashhad, Iran. (2012)

• Best Intern of Firoozgar Hospital. Tehran, Iran. (2011)

• Best prize in Internal Medicine poster session, 11th Iranian Annual Medical Research Congress. Awarded for Iranian Ministry of Health Research Grant. Bandar-Abbas, Iran. (2010) TEACHING EXPERIENCE

• Invited speaker, Introduction to biostatistics for residents at Las Palmas Medical Center El Paso, TX – Summer 2020

• Biostatistics for USMLE, Spring - Summer 2020

• Adjunct Professor of Biology - Fortis College and Institute - Spring 2019

• Teaching Assistant in Hypertension Pharmacology – Vanderbilt University – Department of Pharmacology, Summer 2016 – 2018

• Research Knowledge in Medical Sciences, Medical Journalism and Publication Strategy, IFMSA Training New Trainers, Moderator for Street Workshop on Clinical Epidemiology Studies, General Research Methods and Scientific, Writing Basic Research Knowledge in Medical Sciences workshops, English Scientific Writing in Medical Sciences, and Sampling & Sample Size in Medical Studies – Iran – 2009 through 2014 (Numerous)

• Medical Student Mentor – Rasoul-e-Akram, Ali-Asghar and Firoozgar hospitals – Tehran, Iran – 2012-13 SKILLS & SOFTWARES

• Microsoft office package

• SPSS

• STATA

• R

• Biostatistics

• Epidemiology

• Pharmacodynamic and pharmacokinetic analysis

• Clinical/translational research design

• Grant submissions

• Medicine and physiology

• Clinical Trial design

• EPIC EMR system

• RedCap data management

PUBLICATIONS

1. Moradi S, Mollabashi M, Jafarian Kerman SR. Relation between Serum C-Reactive Protein Levels and Body Mass Index in patients with Polycystic Ovarian Syndrome. Gynecol Endocrinol. 2011 Jul;27(7):480-5

2. Hajsadeghi S, Chitsazaan M, Pouraliakbar HR, Jafarian Kerman SR. Swyer James McLoad syndrome. Iran Cardiovas Res J. 4(3):134-138; 2010

3. Hajsadeghi S, Gholami S, Jafarian Kerman SR, Khamseh ME, et al. IGF-I concentration and changes Scott Jafarian Kerman

9630 Milestone Way Apt 5136 • College Park, MD. 20740 615-***-**** • Email: **********@*****.***

in critically ill patients. J Res Med Sci. 16(2): 170-178, 2011 4. Hajsadeghi S, Gholami S, Gohardehi G, Seifi Moghadam N, Shafiee Sabet A, Jafarian Kerman SR, Moradi M. Association of Troponin T and ICU mortality, a changing trend. Cardiovasc J Afr. 2012 May; 23(4):186-90.

5. Hajsadeghi S, Jafarian Kerman SR, Farsi N. Limb Ischemia and Dyspnea; A Plausible Indication of Paradoxical Embolism. Iran Cardiovasc Res J 2011;5(2):73-76 6. Shidfar F, Moghayedi M, Jafarian Kerman SR, Hosseini S, Shidfar S. Effects of a calcium supplement on serum lipoproteins, apolipoprotein B, and blood pressure in overweight men. Int J Endocriol Metab. 2010; 8(4):194 -200.

7. Moradi S, Salari F, Jafarian Kerman SR. Association between diabetes Complications and leukocyte Count in Iranian patients. J Inflamm Res. 2012;5:7-11 8. Hajsadeghi S, Tavakkoli N, Jafarian Kerman SR, Shahabadi A, Khojandi M. Electrocardiography findings and serum Troponin I in carbon monoxide poisoned patients. Acta Med Iran. 2012; 50(3):185- 91.

9. Hajsadeghi S, Jafarian Kerman SR, Khojandi M, Vaferi H, Ramezani R, Movasseghi Jourshari N, Mousavi SAJ, Pouraliakbar HR. Accuracy of D-dimer/fibrinogen ratio to predict developing of pulmonary thromboembolism in patients admitted to intensive care units. Cardiovasc J Afr. 2012 Sep;23(8):446-56

10. Sezavar SH, Farahani B, Gholami S, Moradi M, Zarei M, Ganji M, Miri S, Khalili N, Jafarian Kerman SR. Association of Aspirin intake and myocardial infarction size. GMJ. 2012; 1(1):35-3 11. Moradi S, Jafarian Kerman SR, Mollabashi M. The effect of Topiramate on weight loss in patients with type two diabetes. J Res Med Sci. 2013 Apr; 18(4):297-302. 12. Hajsadeghi S, Kashani Amin L, Bakhshandeh H, Rohani M, Azizian AR, Jafarian Kerman SR. The Diagnostic Value of N-terminal Pro-brain Natriuretic Peptide in Differentiating Cardioembolic Ischemic Stroke. J Stroke Cerebrovasc Dis. 2013 May; 22(4):554-60. 13. Hajsadeghi S, Jafarian Kerman SR, Pouraliakbar H, Mohammadi R. A huge coronary artery aneurysm in osteogenesis imperfecta: a case report. Acta Med Iran. 2012 Nov; 50(11):785-8. 14. SRJ Kerman. Aspirin Resistance, True or False? GMJ 2 (4), 133-134. (Editorial) 15. Hajsadeghi S, Oraii S, Riahi H, Sezavar S, Ghanooni A, Jafarian Kerman S, Ahmahi R. Atrial Dissociation in a Middle-Aged Patient: a Case Report. Acta Med Iran 2014; 52(8):641-643. 16. Hajsadeghi S, Kerman SRJ, Joodat R, Hejratie M, Vaferi H, Farsi N, et al. Deep Vein Thrombosis, Demographic Characteristics and Risk Factors in Iran. GMJ 2013; 2 (4):135-140 17. Moshar S, Broumandpour M, Mohsenikia M, Jafarian Kermanm SR, Zavareie S, MousaviVaezi SY, Mirlohi SMJ. The Relation between Electrocardiogram Damage Rating and Hospitalization Outcome in Myocardial Infarction. Thrita. 2013 November; 2(2): 52-5. 18. Maleki A, Samandari S, Almeida O, Jafarian Kerman SR, Abdolvand M, Aliyari F, Foroughi S. Correlation Between Hypertension, C-Reactive Protein and Serum Uric Acid With Psychological Well- being. Iran Red Crescent Med J. 2014 July; 16(7): e17205 19. Hajsadeghi S, Samiee S, Hosseini SS, Hassanzadeh M, Jafarian Kerman SR. Novel echocardiographic indices as predictors of immediate recurrence after undersized ring annuloplasty for ischemic mitral regurgitation. Echocardiography. 2015 Sep;32(9):1339-46. 20. Hajsadeghi S, Naghshin R, Hejrati M, Jafarian Kerman SR. Right Ventricular Thrombus in a 36-Year- Old Man with Factor V Leiden. J Teh Univ Heart Ctr 2015;10(1):46-49. 21. Llombart V, Antolin-Fontes A, Bustamante A, Giralt D, Rost NS, Furie K, Shibazaki K, Jafarian- Kerman SR et al. B-type natriuretic peptides help in cardioembolic stroke diagnosis: pooled data meta- Scott Jafarian Kerman

9630 Milestone Way Apt 5136 • College Park, MD. 20740 615-***-**** • Email: **********@*****.***

analysis. Stroke. 2015 May;46(5):1187-95.

22. A Maleki, M Cheraghi, SRJ Kerman, M Montazeri, N Rashidi, R Ghanavati. Aspirin Resistance in Different Doses by Bleeding Time and Urinary 11-dehydro-thromboxane B2. Indian J Physiol Pharmacol 60 (1), 30-37

23. SRJ Kerman. “Rescue-egg” Antioxidants, what they really do? Galen Medical Journal 4 (4), 130-31 24. Hajsadeghi S, Bagheri Ym Manteghi MJ, Firouzi A, Jafarian Kerman SR, Hassanzadeh M. B-type natriuretic peptide and renovascular hypertension; is there any relation? Med Res J 2017 5(6); 1-10 25. Hajsadeghi S, Rahbar MH, Iranpour A1, Salehi A, Asadi O, Jafarian SR. Dobutamine-induced takotsubo cardiomyopathy: A systematic review of the literature and case report. Anatol J Cardiol. 2018 Jun;19(6):412-416.

26. Sandip C, Yangchen SL, Amir S, Rezza JKS, Hisatomi A. Effects of Long- and Intermediate-Acting Dihydropyridine Calcium Channel Blockers in Hypertension: A Systematic Review and Meta-Analysis of 18 Prospective, Randomized, Actively Controlled Trials. J Cardiovasc Pharmacol Ther. 2018 Jan 1:1074248418771341.

27. Hubers S, Wilson, JR, Jafarian-Kerman SR, Brown NJ, et al. DPP (Dipeptidyl Peptidase)-4 Inhibition Potentiates the Vasoconstrictor Response to NPY (Neuropeptide Y) in Humans During Renin- Angiotensin-Aldosterone System Inhibition Hypertension. 2018;72:712–719 28. Hajsadeghi S, Bagheri Y, Ghafouri MH, Jafarian Kerman SR, Hassanzadeh M High-Sensitive Troponin I and Re-Hospitalization in Patients With Decompensated Congestive Heart Failure Acta Medica Iranica 2019, 116-121

29. Wilson, JR; Kerman, SJ; Hubers, SA; Yu, C; Nian, H; Grouzmann, E; Eugster, PJ; Mayfield, DS; Brown, NJ. Dipeptidyl Peptidase 4 Inhibition Increases Postprandial Norepinephrine via Substance P

(NK1 Receptor) During RAAS Inhibition. J Endo Soci 2019, 3(10):178*-****-**. Prinsen JK, Kannankeril PJ, Sidorova TN, Yermalintskaya LV,Boutaud O, Zagol-Ikapitte I, Jafariank- Kerman SR et al. Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension. JACC: Basic and trans Sci. Article in Press. 31. Mashayekhi M, Jafarian-Kerman S, Wilson JR, Brown N. Diabetes, Obesity and Metabolism. In Press UNDERGOING RESREARCH / CONSIDERATION FOR SUBMISSION or PUBLICATION 1. Jafarian-Kerman SR, Oates JA, et al. The effects of resveratrol supplementation on in-vivo and in-vitro platelet activity; a randomized clinical trial (Temporarily on hold) 2. Jafarian-Kerman, SR, Brown NJ; Contribution of Neuropeptide Y (NPY) to Vasoconstriction and Sympathetic Activation in the Setting of Dipeptidyl Peptidase IV (DPP4) Inhibition (accepted for publication)

3. Jafarian-Kerman SR, Strauss DG, Vicente J. Automated Analysis of Drug-induced Electrocardiogram Changes from Cardiac Safety Trials (manuscript ready to be submitted) 4. Jafarian-Kerman SR, Florian J, Strauss DG et al. The role of pupillometry in evaluating opioid reversal effects in an opioid agonist/antagonist in comparison to rebreathing assessments (undergoing)

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