Evan L. Sticca

*** ****** ****** *** ***, Denver, CO 80220

adjkjt@r.postjobfree.com 719-***-****

Seeking intellectually stimulating employment in genetics, informatics, clinical translational science, biostatistics/statistics, or data science with the goal of making a positive difference in the world. Education

University of Colorado Anschutz Medical Campus Aug 2018 – Present PhD, Human Medical Genetics and Genomics Program

• Mentored by Dr. Christopher Gignoux

• Program Representative for Graduate Student Advisory Group to the Dean, Member of Graduate Student Council, panelist on Student Advocates for Mental Health, Movember Foundation Student Ambassador, contributor to PhD Post newspaper

• Relevant Courses: Biostatistical Methods I/II, Responsible Conduct of Research, Survey of Human Genetics, Practical Biological Data Analysis, Legal and Regulatory Environment of Life Science Innovations, Pain, Paradox & Human Condition

State University of New York at Stony Brook Aug 2013 – Dec 2014 Master’s Degree, Department of Ecology and Evolution, Concentration in Applied Evolution

• Graduate Student Researcher in Henn lab; Mentored by Dr. Brenna Henn

• NGS Journal Club, Evolutionary Genetics Journal Club, The Gotham Seminar on Genomics and Statistics, Stony Brook GSO Member, Ballroom Dancing Club

• Relevant Courses: Principles of Applied Ecology and Evolution, Introduction to Ecological Genetics and Genomics, Biometry, Evolutionary Ecology, Graduate Genetics, Computational Biology, Bioinformatics

(Johns Hopkins independent Coursera)

University of Colorado at Boulder Aug 2009 – Aug 2012 Bachelor’s Degree in Evolutionary Biology and Ecology

• Arnett Honors Housing, CU Program Council, CU Fencing Club

• Arts and Sciences Dean’s List Spring 2012

Employment

Weill Cornell Institute for Precision Medicine

Bioinformatics Analyst – (June 2016- June 2018)

Expanded the analytical platform in the Institute for Precision Medicine (IPM). Developed new software tools and built new pipelines for novel bioinformatics analyses in the context of clinically relevant results for cancer patients. Focused on expanding existing pipelines and production of novel ones with regard to efficiency, robustness, reproducibility and interpretability. Developed tools for visualization of results in an intuitive format. Finally, integrated diverse data to look for biologically relevant connections that might not otherwise be apparent. In all this work focused on the goal of using big data for precision medicine breakthroughs in patients' lives. The Rockefeller University (March 2015-June 2016)

Lead Bioinformatics Specialist – (Promoted August 2015-June 2016) Bioinformatics Research Associate – (March 2015-August 2015) Laboratory of Pediatric Disease – Joseph Gleeson Lab Developed and executed bioinformatics pipelines for processing next generation sequence data from whole exome and whole genome samples. Communicated regularly with next generation sequencing centers for coherence on data delivery, formatting and pipeline procedure. Performed well documented variant calling and annotation methods in addition to experimental RNAseq, de novo variant calling and somatic variant calling on specific projects. Responsible for SQL database maintenance of over 7500 individuals and associated calls for more than 2 million variants. Maintained Gleeson lab internal web server and reporting system for variants of potential causal interest. After curating data for postdoctoral scholars, hosted regular meetings addressing informatics concerns, planning for future experiments, and solving issues as they arose. As Lead Bioinformatics Specialist trained and supervised daily workflow of UCSD branch bioinformatics colleagues as well rotating institutional scholars, students, and interns. Additionally provided consultation to SimulConsult clinical diagnostic software providing training data and helping formalize software goals and functionality.

Selected Research Publications

EXaCT-2: Augmented Whole Exome Sequencing Optimized for Clinical Testing in Oncology Hassane et al. 2019, Journal of Molecular Diagnostics Integrative Molecular Analysis of Patients With Advanced and Metastatic Cancer Sailer et al. 2019, JCO Precision Oncology

Longitudinal Changes of One-Carbon Metabolites and Amino Acid Concentrations during Pregnancy in the Women First Maternal Nutrition Trial Gilley et al. 2019, Current Developments in Nutrition Autism risk in offspring can be assessed through quantification of male sperm mosaicism Breuss et al. 2019, Nature Medicine

Integrating Clinical Genomics into Electronic Health Records to Foster Precision Medicine Sigaras et al. 2018, Journal of Molecular Diagnostics Mutations in MBOAT7, Encoding Lysophosphatidylinositol Acyltransferase I, Lead to Intellectual Disability Accompanied by Epilepsy and Autistic Features Johansen et al. 2016, The American Journal of Human Genetics Technical Skills (see LinkedIn for Certifications)

• Computing languages: R (8 years), Python (6 years), Bash scripting and Unix environment (6 years), MySQL (5 years)

• Deploying Pipelines to Cloud Computing environments (AWS, Microsoft Azure) via Docker

• Informatics tools: GATK, Platypus, TopHat, lumpy, Triodenovo, MuTect, Strelka, MIPgen, samtools, sambamba/samblaster, vcftools, bwa, XHMM, H3M2, PLINK/SEQ, snpEff/snpSift, MEGA, GREAT and Enrichr (Gene Ontology Analysis)

• Extensive familiarity in next generation sequencing technology, processing pipelines, data formatting and downstream analysis

• Conversational competency in Spanish

Additional Leadership and Experience

• Student Ambassador for Movember Foundation since November 2018

• Eagle Scout of Boy Scouts of America since December 2005

• Black Belt 1st dan of Go Ju Ryu since August 2009