Yogesh Aher Page *

Yogesh D. Aher, PhD

Medical University of Vienna, Austria

KEY SKILLS

Preclinical Neuroscience

& in vivo Animal Studies

- Behavioral Neuroscience

(Morris Water Maze, Y-Maze)

- Chemobrain, Neuropathic Pain

- Brain Micro-dissection

- Stereotaxic surgery and

histological assessment

- Neurodegerative Diseases

- Vivarium/CRO management

Molecular biology

- Immunohistochemistry, Neuro-

proteomics, Cryosectioning

- in vitro Biochemical profiling

Relevant experience

- Handling and dosing rodents for

major routes (PO, IV, IP, SC)

- Blood and tissue collection for

pharmacokinetic and

toxicology studies, OECD GLP

Biostatistics (GraphPad Prism)

MS-Office (word, excel, ppt)

Electronic notebook: Benchling

Machine Learning, Bioinformatics

Drafting of Ethics committee/

animal study protocols, reports

Other Skills: Project Management,

Quick learner, Team Player, Proactive

11 peer-reviewed publications in

reputed scientific journals

PROFESSIONAL SUMMARY

Efficient Preclinical Scientist

Multidisciplinary scientist with 9+ years of experience in translational research (in vivo, in vitro, in silico) and 2 years of industrial experience in preclinical in vivo CRO and drug discovery start-ups; results communicated through journal articles, reports and talks.

Meticulous research and innovation professional; designed, planned and executed the projects; independently conducted the experiments and interpreted the results.

Research work was focused on animal models of neurodegenerative disease models using MPTP, scopolamine; target identification of novel CNS drugs (cognitive enhancers) led to scientific articles (4 first-author publications); chemotherapy-induced cognitive impairment (CICI) and neuropathic pain (CIPN); studying the impact of a transcription factor and thyroid insufficiency on myelination and oligodendrocytes differentiation.

Effective communicator

Excellent team player, accept feedback and improvise, ready to take on new challenges.

Established multi-institutional collaborations with 3 principal investigators in United Kingdom, Hungary & Slovakia and played a stellar role in providing technical expertise to set up the lab, on-sight training, troubleshooting and following up the progress.

Coordinated with several lab members, professors and different stakeholders to compile in vivo, in vitro and chemistry data for publishing manuscripts.

Execution/Implementation Specialist

Quick to comprehend, adapt and ascertain knowledge; established animal research unit and conducted the proof-of-concept studies generating meaningful data to attract grants.

Start to end project co-ordination while working in a CRO (i.e. from sponsor communication to data archival) with regular project updates to and from the Sponsors.

Documented and maintained standard operating procedures (SOPs) and protocols, drafted animal licenses, helped in acquiring new projects, assisted in the renewal of grants. CERTIFICATES

National GLP Compliance Monitoring Authority’s Workshop on Quality Assurance 2018

Education and training of persons working with laboratory animals, FELASA-B 2014

General Course on Intellectual Property, World Intellectual Property Organization 2013 linkedin.com/in/yogeshaher

+91-997*-***-***

adjhpg@r.postjobfree.com

Yogesh Aher Page 2

ACADEMIC AND RESEARCH EXPERIENCE

Senior Scientist: Preclinical in vivo Neuroscience 2019-Present Enveda Therapeutics India Private Limited, Vizag, Andhra Pradesh, India Senior Research Scientist: Toxicology and Pharmacology 2018-2019 PRADO- Preclinical Research & Development Organization Private Limited, Pune, India Visiting Postdoc: Neural stem cells and myelination 2016 University of Cambridge, Department of Clinical Neurosciences, Welcome Ttrust, MRC Cambridge Stem Cell Institute, Cambridge, UK

Postdoc: in vivo behavioral neuroscience and target identification 2013-2017 Medical University of Vienna, Division of Laboratory Animal Science and Genetics, Core Unit of Biomedical Research, Himberg, Austria

PhD: Computational drug discovery 2008-2012

University of Vienna, Department of Pharmaceutical Chemistry, Vienna, Austria Master of Science (Pharmacy): Computational drug discovery 2005-2007 National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India Bachelor of Pharmacy 2001-2005

University of Pune, Sinhgad College of Pharmacy, Pune, India SELECTED PUBLICATIONS

A novel heterocyclic compound CE-104 enhances spatial working memory in the radial arm maze and modulates the dopaminergic system, Aher et al, Front. Behav. Neurosci., 2016

Effects of R-Modafinil on spatial reference memory and dentate gyrus synaptic plasticity, Shanmugasundaram et al, PLos One, 2017

A daily single dose of a novel modafinil analogue CE-123 improves memory acquisition and memory retrieval, Kristofova et al, Behav. Brain Res., 2018 (#equal contributing first author)

A novel heterocyclic compound CE-103 inhibits dopamine reuptake and modulates dopamine transporter and D1-D3 containing receptor complexes, Sase et al, Neuropharmacology, 2016

(#equal contributing first author)

Full list of 11 publications can be accessed at Pubmed or Google scholar POSTER PRESENTATIONS

14th International Congress on Amino Acids, Peptides and Proteins, Vienna, Austria 2015

European School on Medicinal Chemistry, Urbino, Italy 2011

EFMC’s Joint Meeting on Medicinal Chemistry, Budapest, Hungary 2009

IASTED’s International Conference on Artificial Intelligence, Innsbruck, Austria 2007

International Conference on Chemoinformatics, Pune, India 2007

International Conference on Bioinformatics, New Delhi, India 2006 REFERENCES

Dr. Yasir Ahmed Syed, University of Cambridge, UK. Currently at the Cardiff University as group leader, Tel. +44-29-206*-****, Email: adjhpg@r.postjobfree.com

Asso. Prof. Dr. Harald Hoeger, Division of Laboratory Animal Science and Genetics, Medical University of Vienna, Austria. Tel. +43-223*-*****, Email: adjhpg@r.postjobfree.com

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