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Ph.D. mycobacterial immunology, autophagy

Location:
Bhubaneswar, Odisha, India
Posted:
December 07, 2020

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Resume:

Curriclulum-Vitae

Name

Sex: -

: - Dr. Shradha Mawatwal

: - Female

Corresponding address:-

Nationality : - Indian

Email Id : - adie7s@r.postjobfree.com

Mobile no. : - 993-***-****

D 16/4, Doordarshan colony,

Chandrasekharpur, Dist -

Khurda, P.O.- Sainik school,

Bhubaneswar- 751005, Odisha,

India

Skype ID : -live:shraddhamawatwal

Current position:-

Completed Ph.D. with thesis entitled “Modulation of Autophagy and its Effect on Intracellular Mycobacteria by Calcium Ionophores”.

Supervisor:-

Name : - Dr. Rohan Dhiman

Designation : - Assistant professor

Institution : - Department of Life Sciences, NIT Rourkela Academic qualifications:-

2015 – 2019 : Ph.D. in Life Science, NIT Rourkela, with 8.93 2013-2014 : M.Phil in Botany, Utkal University, with 77.25% 2011-2013 : M.Sc. in Botany, Utkal University, First class with Distinction, 77.5%

2008 - 2011 : B.Sc. in Botany, Utkal University, First class with Distinction, 73.22%

2007 - 2008 : 12th (Physics, Chemistry, Biology) from C.B.S.E. Board, K.V. 2 CRP Bhubaneswar with 70.8%

2005- 2006 : 10th (Mathematics, Physics, Chemistry, Biology) from C.B.S.E. Board, K.V. 2 CRP Bhubaneswar with 76.6%

Research Experience:-

Research Associate : NISER, jatni

Awards and Fellowship:-

Junior Research Fellowship and Senior Research fellowship through Graduate Aptitude Test in Engineering scholarship from MHRD, Government of India. GATE percentile in 2014 – 90.1 percentiles

Publications:-

1. Mawatwal, S., Behura, A., Ghosh, A., Kidwai, S., Mishra, A., Deep, A., Agarwal, S., Saha, S., Singh, R. and Dhiman, R., 2017. Calcimycin mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner. Biochimica et Biophysica Acta (BBA)-General Subjects, 1861(12), pp.3190-3200. 2. Mawatwal, S., Behura, A., Mishra, A., Singh, R. and Dhiman, R., 2018. Calcimycin induced IL-12 production inhibits intracellular mycobacterial growth by enhancing autophagy. Cytokine, 111, pp.1-12.

3. Kidwai, S., Park, C.Y., Mawatwal, S., Tiwari, P., Jung, M.G., Gosain, T.P., Kumar, P., Alland, D., Kumar, S., Bajaj, A. and Hwang, Y.K., Song, C.S., Dhiman, R., Lee, I.Y. and Singh, R., 2017. The dual mechanism of action of 5-Nitro-1, 10-Phenanthroline against Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, pp.AAC-00969. 4. Mishra, A., Behura, A., Mawatwal, S., Kumar, A., Naik, L., Mohanty, S.S., Manna, D., Dokania, P., Mishra, A., Patra, S.K. and Dhiman, R., 2019. Structure-function and application of plant lectins in disease biology and immunity. Food and Chemical Toxicology, 134, pp.110827.

5. Behura, A., Mishra, A., Chugh, S., Mawatwal, S., Kumar, A., Manna, D., Mishra, A., Singh, R. and Dhiman, R., 2019. ESAT-6 modulates Calcimycin-induced autophagy through microRNA-30a in mycobacteria infected macrophages. Journal of Infection, 79, pp. 139-152. 6. Pradhan, N., Parbin, S., Kausar, C., Kar, S., Mawatwal, S., Das, L., Deb, M., Sengupta, D., Dhiman, R. and Patra, S.K., 2019. Paederia foetida induces anticancer activity by modulating chromatin modification enzymes and altering pro-inflammatory cytokine gene expression in human prostate cancer cells. Food and Chemical Toxicology, 130, pp. 161-173. 7. Omanakuttan, M., Konatham, H.R., Dirisala, V.R., Jeevan, A., Mawatwal, S., Dhiman, R., Ly, L.H. and McMurray, D., 2019. Prokaryotic Expression, In Vitro Biological Analysis, and In Silico Structural Evaluation of Guinea Pig IL-4. Molecular biotechnology, 62 (2) pp.104-110. 8. Dewangan, S., Mishra, S., Mawatwal, S., Dhiman, R., Parida, R., Giri, S., Wölper, C. and Chatterjee, S., 2019. Synthesis of Ferrocene Tethered Heteroaromatic Compounds Using Solid Supported Reaction Method, their Cytotoxic Evaluation and Fluorescence Behavior. Chemistry Select, 4(15), pp.4434-4442.

9. Dewangan, S., Barik, T., Mishra, S., Mawatwal, S., Kumari, S., Giri, S., Das, S., Dhiman, R., Wölper, C. and Chatterjee, S., 2018. Half sandwich based rhodamine hydrazone single molecule probe: Light responsive, metal sensing and imaging properties. Applied Organometallic Chemistry, 32(12), pp.e4612.

10. Ekka, B., Nayak, S.R., Achary, L.S.K., Kumar, A., Mawatwal, S., Dhiman, R., Dash, P. and Patel, R.K., 2018. Synthesis of hydroxyapatite-zirconia nanocomposite through sonochemical route: A potential catalyst for degradation of phenolic compounds. Journal of environmental chemical engineering, 6(5), pp.6504-6515.

11. Dewangan, S., Barik, T., Parida, R., Mawatwal, S., Dhiman, R., Giri, S. and Chatterjee, S., 2019. Solvent free synthesis of ferrocene based rhodamine–hydrazone molecular probe with improved bioaccumulation for sensing and imaging applications. Journal of Organometallic Chemistry, 904, pp.120999.

12. Omanakuttan, M., Dirisala, V.R., Konatham, H.R., Madhuri, M., Jojula, M., Mawatwal, S. and Dhiman, R., 2020. Deciphering the Biological Activity of Recombinant Guinea Pig Proteins. Current Trends in Biotechnology & Pharmacy, 14(1). Paper/Poster/Oral talk presented in National/International Conferences 1. Poster presentation on “Calcimycin-induced IL-12 production enhances autophagy and restrict intracellular mycobacterial growth” at the Keystone Symposia on Molecular and Cellular Biology on Autophagy: From Model Systems to Therapeutic Opportunities at Eldorado Hotel & Spa, Santa Fe, New Mexico, USA.

2. Poster presentation on “Calcimycin induced autophagy decreases mycobacterial growth in THP-1 cells through P2RX7 dependent pathway mediated by intracellular calcium” in 5th Global Forum on TB Vaccines, New Delhi, India.

3. Poster presentation on “Calcimycin kills mycobacteria by inducing autophagy through intracellular calcium in p2rx7 dependent pathway” in 44th Annual Conference of the Indian Immunology Society (IIS) (IMMUNOCON 2017), Ahmedabad, Gujarat. 4. Participated in 2nd International conference on frontiers in biological sciences in NITR

(INCOFIBS - 2015).

Research Interest and skills

1. Mammalian cell culture (both adherent and suspension) 2. Polymerase Chain Reaction

3. Maintenance of mycobacterial culture

4. Cell based assays and Immunoassays.

5. Fluorescence microscopy

6. Confocal microscopy

7. Western blot

8. ELISA

9. qRT-PCR

10. FACS

11. Gene silencing

12. Protein purification

13. Plasmid isolation

14. Immunohistochemistry

Personal Competencies:-

Ability to work in a fast-paced environment to set deadlines

Excellent oral and written correspondence with an exceptional attention to detail

Highly organised with a creative flair for project work

Enthusiastic self-starter who contributes well to the team

Good knowledge of word processing, spreadsheets, table and graph generation and use of applicable computer software

Excellent organizational skills

Good working knowledge of scientific terminology, medical and research concepts

Strong communication skills

Excellent interpersonal skills

Proficient use of English language

Referees:-

Dr. Rohan Dhiman

Assistant Professor

Department of Life Science

National Institute of

Technology Rourkela

Odisha 769008 India

Ph: +91-859*******

Email: adie7s@r.postjobfree.com

Dr. Sujit Kumar Bhutia

Associate Professor

Department of Life Science

National Institute of

Technology Rourkela

Odisha 769008 India

Ph: +91-889*******

Email: adie7s@r.postjobfree.com

Dr. Mohammed Saleem

Reader - F

School of Biological Sciences

National Institute of Science

Education and Research (NISER)

Jatni, Odisha 752050 India

Ph: +91-993*******

Email: adie7s@r.postjobfree.com

I declare that the above information is correct and complete to the best of my knowledge and belief. Dr. Shradha Mawatwal



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