Clinical Research Medical

Date of Preparation: April, ****

Personal Data

Name: Joel Edward Lavine, MD, Ph.D.

Work address: Columbia University Medical Center

*** **** ***** ******, ****-105H

New York, NY 10032

<adgxm5@r.postjobfree.com>

Birthplace: Cleveland, Ohio

Citizenship: USA

Academic Appointments

02/2010 -present Department of Pediatrics, Columbia University New York, NY

Professor of Pediatrics (with tenure)

Vice Chair of Pediatrics (Research) (2014-2019)

Chief, Division of Gastroenterology, Hepatology & Nutrition

(2010 – 2020)

Professor of Pediatrics (in the Institute of Human Nutrition)

(11/2016-present)

07/2001 - 02/2010 Department of Pediatrics, University of California San Diego, CA

Professor of Pediatrics (with tenure)

Vice Chair of Pediatrics (Faculty and Fellow Development)

(01/2002 – 12/2009)

Chief, Division of Gastroenterology, Hepatology & Nutrition

(10/1995-02/2010)

10/1995 - 06/2001 Department of Pediatrics, University of California San Diego, CA Associate Professor of Pediatrics

Chief, Division of Gastroenterology, Hepatology & Nutrition

09/1991 - 09/1995 Department of Pediatrics, Harvard Medical School Boston, MA Assistant Professor of Pediatrics

Director, Liver Research

04/1989 - 08/1991 Department of Pediatrics, University of California San Francisco, CA Assistant Professor of Pediatrics

Hospital Appointments

02/2010 - present New York-Presbyterian New York, NY

Morgan Stanley Children’s Hospital

Attending Physician

Director, Division of Gastroenterology, Hepatology and Nutrition

08/1995-01/2010 (Rady) Children’s Hospital San Diego, CA

Senior Attending Physician

Director, Gastroenterology, Hepatology and Nutrition

Director and Co-Founder, Liver Transplantation Program

09/1991– 07/1995 The Children’s Hospital Boston, MA

Assistant Attending Physician

04/1989-08/1991 Department of Pediatrics, University of California San Francisco, CA

Attending Physician

08/1987-08/1991 San Francisco General Hospital San Francisco, CA Attending Physician

Education

09/1980 - 06/1984 University of California San Diego, CA

Doctor of Medicine, awarded 6/1984

09/1976 - 12/1980 University of California Santa Barbara, CA

PhD, Biological Sciences, awarded 12/1980

Thesis: Genetic and Biochemical Characterization of

Tetrahymena Galactokinase

Advisor: Daniel Morse, PhD

09/1971 - 06/1975 University of California Berkeley, CA

AB, Biochemistry, June 1975

Training

07/1986 - 03/1989 Department of Pediatrics, University of California San Francisco, CA

Pediatric Gastroenterology, Hepatology & Nutrition Fellow

Research Training in HHMI/Don Ganem and Harold Varmus

07/1985 - 06/1986 Department of Pediatrics, University of California, San Francisco, CA

Pediatric Resident (short-tracked)

06/1984 - 06/1985 Department of Pediatrics, University of California, San Francisco, CA

Pediatric Intern

Licensure and Board Certification

Licensure

2010-present Medical License, New York State (active)

1985 - 2012 Medical License, State of California (inactive)

1991- 1995 Medical License, State of Massachusetts (inactive)

Board Certification

2008-2018 Certificate of Added Qualification, Transplant Hepatology,ABP #52

2015- 2021 recertification, Pediatrics and Pediatric Gastroenterology, Hepatology, Nutrition

2011- 2015 recertification, Pediatrics and Pediatric Gastroenterology, Hepatology, Nutrition

2005 - 2011 recertification, Pediatrics and Pediatric Gastroenterology, Hepatology, Nutrition

1997 - 2004 recertification, Pediatrics and Pediatric Gastroenterology, Hepatology, Nutrition

1990-1997 initial certification, Pediatrics (ABP #210908) & Pediatric Gastroenterology ABP #150

Honors & Awards

2019 “GI Leader to Know” publication; Becker’s GI and Endoscopy

https://www.beckersasc.com/gastroenterology-and-endoscopy/gi-leader-to-know-dr-joel-lavine-of-new-york-presbyterian.html

1998-2019 Best Doctors in America, (Woodward-White Polling and Research)

2013-2019 U.S. News/Castle-Connolly/New York Magazine; “Top Doctors in New York”

2011-2020 New York “Super Doctors” (Key Media/New York Times Magazine)

2019 Becker’s ASC Review, “117 GI Doctors to Know”

2017 Featured, Nature online article, “Childhood obesity: A growing concern”

https://www.nature.com/articles/d41586-017-05868-y

2014-present Inaugural Fellow of the American Association for the Study of Liver Diseases

Awarded to AASLD members who made significant contributions to Hepatology and the AASLD

2014-2017 Samberg Scholar at New York-Presbyterian Hospital ($500,000)

Recognition of physician leadership in growth initiatives for children’s care

2013-2014 Selected for American Pediatric Society “Success Story in Child Health Research”

Chosen for one of three featured successes in pediatric health advances in America regarding research that led to successful therapy for nonalcoholic steatohepatitis in children (and adults).

2014 “Quote of the Day”, New York Times (June 14) and front-page coverage of Dr. Lavine’s research (June). https://www.nytimes.com/2014/06/14/pageoneplus/quotation-of-the-day-for-saturday-june-14-2014.html?smid=em-share

2010 Presidential Plenary Keynote Address, American Association for the Study of Liver Disease, Boston, MA (3000 attendees)

2008 Congressional citation in House of Representatives Congressional Record, May 21, 2008, for NIH Study for Fatty Liver in Children. Joel Lavine, multi-center study lead, PI, NASH Clinical Research Steering Committee Chair

2007 - 2018 Who’s Who in America (Marquis)

2006 Quality and Innovation Award; The Children’s Hospital, San Diego

Single award per year for most improved access, available services and patient satisfaction scores for the Division of Gastroenterology and Hepatology

1995 - 2001 Who’s Who in the West

1993 - 1997 Who’s Who in the East

1991 North American Society for Pediatric Gastroenterology and Nutrition

Young Investigator Award Finalist

1988 American Association for the Study of Liver Disease

Outstanding Pediatric Research Prize

1984 Class of 1984, UCSD Medical School Graduation Speaker

1983 - 1984 A. Baird Hastings Medical Honor Society

University of California, San Diego

1981 - 1983 Ruben Fleet Foundation Scholarship (UCSD Medical School)

1980 - 1983 B’nai Brith/Hillel Foundation Scholarship at UCSD School of Medicine

1975 Graduation with honors from UC Berkeley

Academic Service

Columbia University Medical Center

2020 Reviewer, Columbia Precision Medicine Initiative, Irving Institute for Clinical and Translational Sciences, Columbia University

2020 Reviewer, Pilot and Collaborative Studies Resource Grants, Irving Institute for Clinical and Translational Sciences, Columbia University

2020 Member, Internal Advisory Committee, Irving Institute for Clinical and Translational Sciences (U54 from NCATS)

2019-24 Mentor, T32 Training Grant in Pediatric Endocrinology and Diabetes,

Department of Pediatrics, Columbia University

2019-24 Mentor, T32 Training Grant in Endocrinology and Diabetes,

Russ Berrie Institute for Diabetes, Dept of Internal Medicine, Columbia University

2018-19 Steering Committee, Opioid Crisis Response, Irving Clinical and Translational Resource, https://www.irvinginstitute.columbia.edu/about-us/key-initiatives/opioid-crisis-response

2018 Scientific Reviewer, Pilots and Collaborative Resources, Irving Clinical and Translational Resource

2018 Symposium organizer, Irving CTRI for “Integrating Special Populations”, topic of

“Environmental Toxicants and Human Health Across the Lifespan” (May)

2018-present Director, Enrichment Core, NIDDK P30 Digestive Health Center Core Grant

(Precision Medicine Digestive Disease Research Center at Columbia University)

In charge of quarterly work-in-progress meetings, visiting professor programs, annual symposia, invited lectureships, core enrichment activity and mini-sabbatical programs.

2018-present Member, Pilot and Feasibility Steering Committee, NIDDK P30 Digestive Health Center Core (Precision Medicine Digestive Disease Research at Columbia University)

2016-present Faculty, Institute of Human Nutrition (Professor)

2017-2018 Member, Physician Scientist Development Committee for Burroughs Wellcome Award

2017-2020 Member, Dean’s Task Force on Opioid Intervention; Irving Clinical and Translational Research Institute

Co-Facilitator, Opioid Brainstorming Symposium on Therapeutic Interventions

2017- present Organizer/Liason, Continuing Medical Education regarding child health

2017-2018 Representative (Pediatrics), Basic Science Department Chairs Committee

2016-present Member, Steering Committee for Columbia Translational Therapeutics Resource

Program, Irving Clinical Research and Translation Center

2016-present Inaugural member, Columbia Summer Research Institute (CSRI) Advisory Board

2016-present Inaugural member, Steering Committee for Translational Research Awards Pilot,

Clinical and Translational Research Institute

2016-present Member, Columbia University Institute for Human Nutrition

2016-21 Director/Supervisor, Pediatric Hub for the Irving Clinical and Translational Science Research Institute, “Integrating Special Populations”

2016-current Judge/Abstract Reviewer, Annual Medical Student Research Day,

Columbia College of Physicians and Surgeons

2011, 2015 Reviewer, Irving Institute for Clinical and Translational Research Awards for Collaborative and Multi-Disciplinary Pilot Research and K12 Awards

2015-20 Member, Internal Advisory Board, Institute for Human Nutrition

2014-2015 Member, Children’s Health Strategic Planning

2013 - present Member, Women and Children’s Research Institute Steering Committee

2012 - present Member, Russ Berrie Diabetes Research Center

2012 - 2013 Member, Digestive Health Strategic Planning Initiative

2012 - 2013 Member, 2020 Vision/Strategic Planning Committee

Department of Pediatrics, Columbia University Medical Center

2018 Member, Driscoll Scholar Selection Committee

2017-2018 Member, Irving Scholars Grant Review Committee

2016-2018 Chair, Search Committee for Chief of Hematology/Oncology/Bone Marrow Transplant

2016-2018 Chair, Underfunded Research Committee (for Career Development Awards)

2015-2018 Chair, Bridge Committee (for research funding)

2015 Member, Compensation Committee

2014-2017 Chair, Research Committee

Works with Chair of the Department to foster research development, facilities, space, core resources, information technology, translational conferences

2014-2018 Member, Chairman’s Cabinet

2014-15 Member, Search Committee for Infectious Disease Division Chief

2013 Chair, Ad hoc Promotion Committee for Hematology/Oncology Chief

2012 - 2013 Chair, Department of Pediatrics Clinical Operations Committee

2012 - 2013 Co-organizer, Junior Faculty Development Program

2011 - 2017 Member, Fellows Research Awards Committee

2011, 2014 Member, John Driscoll Award Selection Committee

2010-2018 Member, Fellowship Scientific Advisory Council

Department of Pediatrics, University of California, San Diego

2007-2010 Member, Steering Committee, Digestive Disease Research Development Center (NIDDK)

2005-2009 Member, School of Medicine Strategic Planning Initiative

Primary coordination (with UCSD Department Chairman) for formation of Foundation joining UCSD Health Sciences, Faculty practices, and Rady Children’s Hospital. This effort formed the 5th largest academic Children’s Hospital in the US in 2010

2009 Organizer, Translational Initiatives in Child Health Symposia

Brought together UCSD, Salk Institute, Scripps Research Institute, Burnham Institute for interdisciplinary lectures on child health to organize basic and clinical science collaborations in San Diego

2004-2009 Chair, Faculty and Fellow Development

2004-2009 Member, UCSD Research Space Allocation Committee

2007 Organizer/moderator, Young Faculty Research and Award Symposium

2005 - 2010 Member, Clinical Investigation Institute, University of California, San Diego

2002-2010 Member, Executive Committee, UCSD/Children’s Specialist’s Medical Group

1999-2010 Medical Director, Pediatric Liver Transplantation

With the Director of Transplant Surgery, brought first liver and living –related donor transplant program to San Diego County and Arizona

2002 - 2005 Inaugural member, Academy of Clinician Scholars

2000-2002 Department representative, Academic Senate

Department of Pediatrics, Harvard Medical School

1991 - 1995 Research Director, Hepatology

1991-1995 Member, Fellow Selection Committee

Professional Organizations and Societies

Membership and Positions:

2018- present Clinical Advisory Committee, NASH Alliance for Federal Policy

2018-present Lead Columbia Physician-Scientist- Coalition for Pediatric Medical Research

2018-2019 Professional member, New York Academy of Sciences

1991-present North American Society for Pediatric Gastroenterology, Hepatology and Nutrition

Lecturer, Post-Graduate Course for World Congress of GI/Nutrition (2016)

Member, Nominating Committee (2014)

Member, Awards Committee (2008-2009)

Member, Committee on Training (2001-2004)

Co-Chair, Symposium on Pediatric Liver Diseases (1991)

Member, (1991-present)

1989-present American Association for the Study of Liver Diseases

Abstract Reviewer, Topics on Pediatric Hepatology: Pediatric Liver Disease - Basic Science; Biliary Atresia and Cholestasis; Viral and Autoimmune Hepatitis; Metabolic and Genetic Diseases; Pediatric Liver Transplantation 2019

Moderator, Placebo Arm and Lifestyle Management in Clinical Trials Session, AASLD and EASL Symposium on “Clinical Endpoints in NASH Conference”

Washington DC, July 2018

Guidelines Committee, Nonalcoholic Fatty Liver Disease, 2011-2021

Moderator, Clinical Workshop, Research in Children and Special Populations 2014

Inaugural Fellow of the American Association for the Study of Liver Diseases 2012-

Presidential Plenary Speaker, 2010

Member, Grants and Awards Committee (2008-2010)

Moderator, Plenary Session for Young Investigators (2008)

Reviewer, Liver Disease Research Agenda Committee for the NIH (2004)

Member, Clinical Research Committee (2001-2004)

Member, Research Grant Selection Committee (1998)

Member, Basic Science Research Committee (1995-1998)

Co-Chair, Plenary session on “Viral Hepatitis” (1994)

Member, (1988-present)

2003-present American Pediatric Society (elected)

Workshop Reviewer (2011)

Member, (2003-present)

2003-present Society for Pediatric Research (elected)

Member, (2003-present)

2008 American College of Gastroenterology

Member/sole pediatrician Task Force on Obesity (2008)

Member, Physician Education Committee (2008)

2007- present International Society for Pediatric Gastroenterology, Hepatology and Nutrition, Member, Working Group on Management of Obesity, Worldwide Consensus (2007)

Member, Working Group on Management of Pediatric Acute Liver Failure (2005-2008)

1994 - present American Liver Foundation

Member, National Medical Advisory Committee (2019 commence)

Member, Committee for Distinguished Lifetime Liver Research Award (1997)

Member, Medical Advisory Board (1996-2010)

Member, Board of Directors (1996-2001)

Member, Grant Review Committee (1994-1997)

Member (1994 - present)

1992 - present American Association for the Advancement of Science

Member

1990 - 2010 Western Society for Pediatric Research

Member

1989 - present American Gastroenterological Association

Nominee, Liver and Biliary Section Vice-Chair, 2020

Abstract Reviewer, Pediatric Liver Metabolic Diseases, 2020

Guidelines Committee, Nonalcoholic Fatty Liver Disease (2011-2016)

Member/sole pediatrician, Task Force on Obesity (2004)

Chair, Digestive Disease Week Symposium for North American Society for Gastroenterology and Nutrition (1991)

Member (1989 – present)

1989 - 2011 American Academy of Pediatrics

Member

Consultative:

National Institute of Health Research

2002-present Nonalcoholic Steatohepatitis Clinical Research Network (NIDDK)

Principal Investigator, (2002-2024)

Member, Executive Committee (2002-2024)

Co-Chair, Steering Committee (2002-2024)

Selected presenter, External Advisory Committee (2013, 2017)

Co-chair and reviewer, Genetics Committee (2010-2024)

Member, Ancillary Studies Committee (2010-2019)

Member, Radiology Committee (2009-2019),

Member, Publications and Presentations Committee (2009-2024)

Member, Pilot and Feasibility Committee (2003-2009)

Chair, Pediatric Committee (2002-2024)

Co-Chair, Database Committee (2002-2024)

2019 Member, Foundation for the National Institutes of Health (FNIH), NIMBLE Consortium (Non-invasive Markers of Metabolic liver Disease)

2018 NIDDK Intramural Program for Hepatology Research Personnel

Reviewer

2017 NIH/National Center for Advancing Translational Sciences; Special Emphasis Panel on Preclinical Research Based on Existing Repurposing Tools. Special Emphasis Panel/Scientific Review Group 05 ZTR1 DPI-2 (01)

Reviewer

2016 NIH/Scientific Review for Kidney, Nutrition, Obesity and Diabetes, Population Sciences and Epidemiology, Collaborations between NIH Intramural/Extramural Investigators; ZRG1 PSE-B 60 C, PAR15--287

Reviewer

2016 NIH/National Center for Advancing Translational Sciences; Special Emphasis Panel on Preclinical Research Based on Existing Repurposing Tools.

Reviewer

2015 NIH/NICHD, Expert Scientific Consultant Panel for Adolescent Bariatrics:

Assessing Benefits and Risks (Teen LABS)

Chairperson and reviewer

2014 NIH R01 Ancillary Studies for Liver Diseases, 2014/10 ZDK1 GRB-C (O1) 1

Reviewer

2014 NIH/CSR Special Emphasis Panel, Population Sciences and Epidemiology Integrated Review Group, 2014/05 ZRG1 PSE-R (02) M

Reviewer

2013 NIH R01 Grant Review, Center for Scientific Review, Population Sciences and Epidemiology Integrated Review Group 2013/05 ZRG1 PSE-R (03) M

Chairperson-Reviewer

2012-2013 NIH National Center for Advancing Translational Sciences, Therapeutics Discovery Section, ZTR1 CI-9 (01)

Reviewer

2012 NIH Population Sciences and Epidemiology, “Member Conflicts: Chronic Disease Epidemiology” ZRG1 PSE-P (02)

Reviewer

2011 NIH Center for Scientific Review, Population Sciences and Epidemiology Integrated Review Group, Metabolic Disorders ZRG1 PSE H(02)

Reviewer

2011 NIDDK, Special Emphasis Panel (ZDK-GRB8-M3) Ancillary Studies to Major Ongoing Clinical Research Studies of Scientific Interest to the NIDDK (R01)

Chairperson-Reviewer

2010 NIH/NICHD, Expert Scientific Consultant Panel for Adolescent Bariatrics: Assessing Benefits and Risks (Teen LABS)

Chairperson-Reviewer

2010 NIDDK, Grant Review Panel for T32, K24, and K23 applications (ZDK1 GRB-7),

Chairperson-Reviewer

2010 NIDDK, Special Emphasis Review Panel, Acute Liver Failure (adults & children),

ZDK1GRB-7(02)

Chairperson-Reviewer

2010 NIDDK, Mentored Applications for Digestive Diseases and Nutrition, ZDK1 GRB-7(03)

Reviewer

2009 NIDDK, Special Emphasis Panel on Immunology in Liver Disease, Grant Review

ZDK1 GRB-N (J2)

Chairperson-Reviewer

2007 NIDDK, Scientific Review Group NIH ZDK1GRB-N (M2) (1)

Reviewer

2007 NIDDK Workshop on Nuclear Hormone Receptors in Digestive Diseases

Co-organizer/Moderator/Lecturer

2006 NIDDK, Scientific Review Group, 2006/08 ZDK GRB N(MI)

Reviewer

2003 NIDDK, Scientific Review Group, (ADK1 GRB-7 04)

Reviewer

2002 NIDDK, Scientific Review Group, (ZDK1GRB-2MIR)

Reviewer

2002 NIDDK Review Branch C Committee (training programs and career development awards)

Reviewer

NIH Data Safety and Monitoring Boards

2019-2014 NIDDK, Surgical or Medical Treatment for Pediatric Type 2 Diabetes

Member

2012-2017 NICHD, Hyperglycemia and Adverse Pregnancy Outcomes

Chair/Reviewer

2009-2010 NIDDK, Cholestatic Liver Disease Research and Education Network (ChiLDREN)

Chair/Reviewer

2004-2009 NIDDK, Biliary Atresia Research Consortium (BARC)

Chair/Reviewer

1998-2003 NIDDK, Acute Liver Failure

Member

U.S. Food and Drug Administration

2013 American Association for the Study of Liver Diseases/Food and Drug Administration Public Workshop for Trial Designs and Endpoints for Liver Disease, “Pediatric Specific Trial Design and Endpoints” and “Trial Design Considerations and Endpoint for Development of Diagnostics for Pediatric Subjects”

Invited lecturer, panelist, moderator

2012-2015 Endocrinology and Metabolism Section; External Advisory Committee

Consultant/employee to provide recommendations on labeling of pharmaceuticals that affect metabolism/liver/obesity

2007 US Food & Drug Administration

Consultant regarding thiazolidinedione trials in children (a drug for type 2 diabetes)

U.S. Department of State

2002 Civilian Research and Development Foundation

Grant Reviewer

International

2020 Research Foundation-Fonds Wetenschappelijk OnderzoekVlaanderen (FWO) Excellence Prizes; Brussels, Belgium

International Jury Reviewer, May

2018-20 NASH Alliance

Clinical Advisory Committee

2018-20 Chronic Liver Disease Foundation

Advisory Board

2017 European Science Foundation, University of Turin

Grant Reviewer

2016, 2018 Medical Research Councils, United Kingdom.

Grant Reviewer

2016 Netherlands Organisation for Health Research and Development (ZonMw) Translational Research Programme

Grant Reviewer

2015-19 The Liver Forum: Facilitating Drug Development for the Treatment of Liver Disease

European Association for the Study of Liver Disease and American Association for the Study of Liver Disease, in collaboration with pharmaceutical and regulatory agencies

Invited Member and Section Leader on Pediatric Drug Development, Vienna, Austria

Executive Committee for the Liver Forum (2015-2107)

Chair, Pediatric Section (2015-2017)

2015 Czech Health Research Council, Ministry of the Czech Republic

Grant Reviewer

2014-16 Global Pediatric Research Network Advisory Board

Member

One of 25 members from academia, pharma, FDA and NIH to form a global network for pediatric clinical trials, to include Columbia University as an inaugural institution

2013 Health and Medical Research Fund under the Hong Kong Special Administrative Region

Grant Reviewer

2012-2018 Qatar National Research Fund, Undergraduate and Graduate Research Experience Program

Grant Reviewer

2012 Raine Medical Research Foundation (Australia) Grant Review Panel

Grant Reviewer

2011-2018 Wellcome Trust Foundation (United Kingdom)

Grant Reviewer

National, Non-federal

2018-20 Site Lead, Institute for Advanced Clinical Trials for Children (iACT)

Best Practices, Education and Tools Committee

2017-18 Co-organizer, New York Academy of Sciences, Symposium on Therapeutic Developments in Fatty Liver Disease (Feb, 2018), NY, NY

2016- Chronic Liver Disease Foundation

Expert Committee Panel/Advisor <chronicliverdisease.org>

2008 Cystic Fibrosis Foundation, Grant Review panel

Grant Reviewer

2007 Cincinnati Children’s Hospital Medical Center Board of Trustees,

Research Foundation and Research Committee

Scientific Advisory Committee, and Reviewer

2004 American Medical Foundation for Peer Review and Education

Reviewer

Industry Consultant

2020 Surrozen, Inc. South San Francisco, CA

2020 Intercept Pharmaceuticals, New York, NY

2020- Thetis Pharmaceuticals, Branford, CT (http://thetispharma.com/cms2/about/advisors/)

2019-20 Novo Nordisk, Denmark

2018-19 Cymabay Therapeutics

2017-19 TARGET PharmaSolutions, NC

2017-18 Pippin Therapeutics, Boston, MA

2017-18 Novartis, Basel, Switzerland

2017-19 Merck and Co., Inc., Kenilworth, NJ

2017-18 Janssen Inc. Jersey City, NJ

2017-18 Gilead, Foster City, CA

2017-18 Bristol Myers Squibb, Lebanon, NJ

2017-18 BASF/Pronova BioPharma, Lysaker, Norway

2017-19 Viking Therapeutics, San Diego, CA

2016-17 Allergan Pharmaceuticals, Jersey City, NJ

2016-17 Albireo Pharmaceuticals, Sweden

2016 Takeda Pharmaceuticals, Chicago, IL

2016 Jefferies LLC, “Biotech Research and Development Summit”, New York, NY

2016-18 Humana Physician Advisory Board, Louisville, KY

2015-18 Merck Pharmaceuticals, Expert Input Forum Advisor, Lebanon, NJ

2015 Prestige Brands, New Brunswick, NJ

2015-2017 Alexion Pharmaceuticals, Boston, MA

2015-2019 Pfizer Pharmaceuticals, Rye Brook, NY

2015-19 Genfit Pharmaceuticals, Paris, France

2011-19 Somalogic, Inc. Boulder, CO

2013-2014 Immuron Ltd. Pharmaceuticals, Southbank, Australia

2013 Millenium Pharmaceuticals, Inc., Cambridge, MA

2013, 2017 Gilead Sciences, Foster City, CA

2013 Merck, Sharp and Dohme, Rahway, NJ

2013-2014 Crosscare/Colief, Dublin, Ireland

2011-2015 Synageva Pharmaceuticals, Lexington, MA

2011 Trinity Partners, Waltham, MA

2010 Quark Pharmaceuticals, Fremont, CA

2008 Takeda Pharmaceuticals, Chicago, IL

Journal Reviewer:

Journal of Clinical Investigation, Gastroenterology, Hepatology, Journal of Pediatric Gastroenterology and Nutrition, Pediatrics, Digestive Diseases and Sciences, Perinatal Diagnosis, Journal of Pediatrics, Teratology, Mayo Clinic Proceedings, Pediatric Research, American Journal of Gastroenterology, Diabetes Care, Gut, Clinical Gastroenterology and Hepatology, Journal of Clinical Gastroenterology, Journal of the American Medical Association, Journal of the American College of Nutrition, Alimentary Pharmacology and Therapeutics, Liver International, Diabetes/Metabolism Research and Reviews, New England Journal of Medicine, Metabolism-Clinical and Experimental, Hormone Research, International Journal of Pediatric Obesity, Annals Internal Medicine, Journal of Pediatric Endocrinology and Metabolism, European Journal of Gastroenterology and Hepatology, BioMed Central Gastroenterology, Metabolism, PLoS One, BMC Biochemistry, Endocrinology, Nature Reviews Gastroenterology and Hepatology, BMC Endocrine Disorders, American Journal of Respiratory and Critical Medicine, Journal of Hepatology, Proceedings of the National Academy of Science (PNAS), European Medical Journal-Hepatology, Childhood Obesity, Journal of the American Medical Association-Internal Medicine; Nutrition, Metabolism and Cardiovascular Disease, British Medical Journal, Molecular and Cellular Endocrinology, Contemporary Clinical Trials, J Mol Diagnostics, BMC Pediatrics, BMC Medical Genetics.

Editorial Boards:

2012-2015 Advances in Anatomic Pathology

Editorial Board

2012- present BMC Gastroenterology

Editorial Board

2012 Seminars in Liver Disease (Pediatric Liver Diseases)

Guest Editor

2008-present Peds Focus

Editorial Board

2010-present Hepatic Medicine: Evidence and Research

Editorial Board

2009-present Journal of Experimental and Clinical Gastroenterology

Editorial Board

2006-2011 Hepatology

Editorial Board (2006-2011)

Editorial Board (1994-2001)

Advisory Committee, Hepatology Elsewhere (1994-2001)

2006-2009 World Journal of Gastroenterology

Editorial Board

1994 Seminars in Liver Diseases (Pediatric Liver Diseases)

Guest Editor

Fellowship and Grant Support

Present Support:

07/01/19- 06/30/24 Clinical Research in Nonalcoholic Steatohepatitis (continuation)

NIDDK U01DK61734-18;

Total direct and indirect: $6,000,000

PI: Lavine (3.6 calendar months); Chair of Steering Committee

07/01/16-06/30/21 Epigenetic Markers of Severity in Nonalcoholic Fatty Liver Disease

NIDDK R01 DK107735-01/A1

Project Director-J. DiStefano Co-investigator: J. Lavine (0.6 calendar mo)

07/01/16-06/30/21 Clinical and Translational Science Award for Columbia University

NCATS/NIH 5UL1TR001873-02 $58.4 Million total costs

PI: M. Reilly; Pediatric Hub Director: J. Lavine (1.2 calendar mo)

This five-year grant allows the Irving Institute to increase its focus on precision medicine in alignment with Columbia University’s Precision Medicine Initiative, by providing substantial resources for training and research in this emerging branch of medicine and for developing translational therapeutics and to integrate special and underserved populations, including children and others with translational research efforts across the human lifespan.

07/01/19-06/30/24 Multidisciplinary Training in Translational Gastrointestinal and Liver Research

NIDDK T32 5 DK083256 (renewal)

Direct support funds: $130,500/y

PI: T Wang, MD; Associate Program Director: Lavine

09/25/17-08/31/22 Advancing Clinical Trials for Children

1U18FD006297-01 Direct Support Funds $1,000,000/year

Institute for Advanced Clinical Trials for Children, Inc. (iACT)

I-ACT for Children, Global Pediatric Clinical Trials Network

PI: E. Connor. Site Champion/PI: J. Lavine (for CUMC Child Health)

09/01/2019-08/31/21 Phase 1 Trial of Elafibranor for Pediatric NAFLD

Genfit Pharmaceuticals- $342,000

PI: J. Lavine

11/23/11-11/22/19 Multicenter-Prospective, Long-Term, Observational Registry of Pediatric Patients with Inflammatory Bowel Disease

DEVELOP/Janssen/Centocor

Direct support funds: $80,000

PI: Lavine

Past Support:

07/01/14- 06/30/19 Clinical Research in Nonalcoholic Steatohepatitis

NIDDK U01DK61734-17;

Direct support funds: $6,400,000

PI: J. Lavine (4.2 calendar mo)

07/01/14-06/30/19 Multidisciplinary Training in Translational Gastrointestinal and Liver Research

NIDDK T32 5 DK083256

Direct support funds: $130,500/y

PI: T Wang, MD; Associate Program Director: J. Lavine

07/01/18-09/30/18 MRI body composition profiling and metabolomics profiling to determine changes after bariatric surgery in adolescents

NIDDK T35 for Columbia P&S medical student Zach Pitkowsky, MS1

Mentor: J. Lavine (PI)

09/01/15-08/31/18 Empire Clinical Research Investigator Program for Pediatric Obesity Education and Research

New York State Department of Health/NYP

Direct support: $1,

Contact this candidate