*

Lemuel F. Melecio Rodríguez, MD

Telephone: 939-***-****

E-mail: adgtnc@r.postjobfree.com

SUMMARY OF QUALIFICATIONS

Accomplished healthcare professional with 10+ years of experience in scientific research in academic setting and more than two years of experience in clinical research. Expertise in scientific methodology, analysis, interpretation and communications. Experience in medical diagnosis, communicating with patients, and coordinating clinical trials. Knowledgeable about GCP and GLP compliance. High-impact interpersonal, verbal and written communication skills with experience in development and management of relationships with external collaborators, academic partners, government organizations, and internal stakeholders. Published author and successful speaker at scientific meetings. Fluent in Spanish and English.

EDUCATION

MD – Universidad Iberoamericana, School of Medicine, Santo Domingo, Republica Dominicana. GPA: 3.29 (JAN 2009 – JUN 2013)

BS, Cellular and Molecular Biology Major – Department of Science and Technology, MIE Project Scholarship, Universidad Metropolitana, San Juan, Puerto Rico. GPA: 3.40

(AUG 2004 – JUN 2008)

LICENSES

Physician Assistant Certification of the Puerto Rico Department of Health, License # 751-P.A.

WORK EXPERIENCE

Clinical Research Coordinator

Pan American Center for Oncology Trials, LLC

Hospital Oncológico, Puerto Rico Medical Center

2nd Floor –Barrio Monacillos

Río Piedras, Puerto Rico 00935

June 2020 – present

• Responsible for ensuring study is compliance with local and federal laws and regulations

• Conducts or participates in the informed consent process

• Recruits and screens potential study participants and performs intake assessments

• Creates and/or maintains all documents and records related to the study

• Acts as a point of reference for study participants by answering questions and keeping them informed on the study progress

• Maintaining detailed records of studies as per FDA guidelines, including things such as drug dispensation

2

Clinical Trial Assistant

Gastroenterology Cancer Prevention,

School of Medicine, Medical Science Campus,

UPR

March 2017 – December 2019

• Assist with the coordination of every aspect of the clinical trials.

• Oversee completion of safety documentation for all trials and ensure that staff have all required safety certification and training.

• Manage patient recruitment and oversee patient compliance in each study.

• Asses that each protocol is implemented appropriately to obtain the required data from each study.

• Conduct surveillance of adverse effects and asses proper use of the study agent.

• Serve as primary contact with the pharmaceutical companies who sponsor the clinical studies.

Research Technician and Animal Breeding Assistant

Department of Anatomy and Neurobiology, School of Medicine, Medical Science Campus, UPR

June 2014 – June 2016

• Managed the laboratory, ensuring that safety compliance was in order and that all the materials and equipment were in place for the students and researchers to conduct the studies.

• Managed a study that was part of the research grant; designed and conducted experiments with the Principal Investigator, performed literature searches, and developed publications.

• Maintained the laboratory equipment including HPLC and Microdialysis.

• Created a C57 mouse breeding colony that was used for the laboratory studies. Clinical Consultant/Costumer Care

HUMANA Medicare Advantage 5 Star Program

TELEMEDIK (Call Center)

August 2013 – November 2013

• Conducted phone calls to patients who were in the HUMANA Medicare Advantage 5 Star Program to assess compliance with medication and treatments.

• Discussed with patients the benefits of the HUMANA program and provided advice on best practices for patients to gain the most advantage on their treatment. RESEARCH EXPERIENCE

• Spring 2018– Winter 2019: Phase II Trial of Weekly Erlotinib Dosing to Reduce Duodenal Polyp Burden Associated with Familial Adenomatous Polyposis. Comprehensive Cancer Center University of Puerto Rico.

• Spring 2017– Winter 2019: Randomized, Double-blind, Placebo-controlled Trial of Meriva (curcuminoid) as a Candidate Chemoprevention Agent for Gastric 3

Carcinogenesis. Comprehensive Cancer Center University of Puerto Rico.

• Spring 2017– Winter 2019: Phase I Trial of a Therapeutic DNA Vaccine for Chronic Hepatitis C Virus (HCV) Infection. Comprehensive Cancer Center University of Puerto Rico.

• Spring 2017– Winter 2019: Targeted Chemoprevention of Gastric Carcinogenesis in High Risk Populations. Comprehensive Cancer Center University of Puerto Rico.

• Spring 2016–Summer 2016: C57BL/6J Mice Breeding for Ethanol Intake Studies. Department of Anatomy and Neurobiology, School of Medicine Medical Science Campus, UPR.

• Summer 2014–2016: Prefrontal Glutamate Plasticity in Adolescent C57BL/6J Mice Drinking Alcohol. Department of Anatomy and Neurobiology, School of Medicine Medical Science Campus, UPR.

• Summer 2007: A Cooled Water-irrigated Intraesophageal Balloon to Prevent Thermal Injury During Cardiac Ablation: Experimental Study Based on an Agar Phantom. Instituto de Biomedicina de Valencia, Valencia, Spain.

• Sumer 2006: Cell Cycle Progression Analysis of Galactosemic Lens Epithelial Cells in Culture Using Flow Cytometry and Propidium Iodide Staining. Universidad Metropolitana, San Juan, Puerto Rico.

• Summer 2005: Western Blot Analysis of Cyclins in Galactosemic Lens Epithelial Cells in Culture. Universidad Metropolitana, San Juan, Puerto Rico.

• Fall 2004 and Fall and Spring 2005, 2006, 2007: Cell Cycle Changes in Galactosemic Lens Epithelial Cells. Universidad Metropolitana, San Juan, Puerto Rico.

TRAINING AND CERTIFICATIONS

• Yale Center for Clinical Investigation Clinical Research Workshops - Sponsored by Puerto Rico Consortium for Clinical Investigation.

• Biosafety Complete Training Series, COLLABORATIVE INSTITUTIONAL TRAINING INITIATIVE (CITI PROGRAM)

• Good Clinical Practice, COLLABORATIVE INSTITUTIONAL TRAINING INITIATIVE (CITI PROGRAM)

• Health Information Privacy and Security (HIPS) for Clinical Investigators, COLLABORATIVE INSTITUTIONAL TRAINING INITIATIVE (CITI PROGRAM)

4

• Human/Biomedical Research, COLLABORATIVE INSTITUTIONAL TRAINING INITIATIVE (CITI PROGRAM).

• Certification for Management of Regulated Biomedical Waste.

• Certification for Management and Exposure to Human Blood Borne Pathogens.

• Certification and Training of Global Harmonization System. CLINICAL ROTATIONS (HOSPITAL EXPERIENCE)

• Internal Medicine, Hospital de la Concepción, San German, Puerto Rico.

• Surgery, Hospital Dr. Félix María Goico, Santo Domingo, Dominican Republic.

• Psychiatry, Hospital Psiquiatrico Padre Billini, Santo Domingo, Dominican Republic.

• Pediatrics, Hospital Infantil Dr. Robert Reid Cabral, Santo Domingo, Dominican Republic.

• Ob/Gyn, Hospital de la Mujer Dominicana, Santo Domingo, Dominican Republic.

• Family Medicine, Centro de Atencion Primaria el Caliche, Santo Domingo, Dominican Republic.

AWARDS

• 2007, Financial A i d A w a r d, S A C N A S Conference, Kansas City, Missouri

• 2006, Best Poster Presentation Award, MIE Dissemination Conference, Bowie, Maryland

• 2006, Best Poster Presentation Award, XVII MIE Undergraduate Research Symposium, MIE Program at UMET, San Juan, Puerto Rico

• 2006, Best Poster P r esentation Award, Research Poster Symposium, Arizona State University, Tempe, Arizona

• 2006, Financial Aid Award, SACNAS Conference, Tampa, Florida

• 2005, Financial Aid Award, SACNAS Conference, Denver, Colorado

• 2004, 2005, 2006, 2007, Model Institutions for Excellence Scholarship, Universidad Metropolitana, San Juan, Puerto Rico

5

PRESENTATIONS AT SCIENTIFIC MEETINGS

• 2019, Gastrointestinal Oncology Conference: Innovation in Endoscopic, Surgical and Oncologic Approaches, San Juan, Puerto Rico

• 2019, El Nuevo Camino Contra el Cáncer, PanOncology Trials, San Juan, Puerto Rico

• 2018, 11th AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, New Orleans, Louisiana

• 2018, Investigators’ and Site Coordinators’ Opportunity for Research Excellence

(I-SCORE), NCI DCP Early Phase Cancer Prevention Clinical Trials Program Annual Meeting, Rockville, Maryland

• 2016, 25

th

Puerto Rico Neuroscience Conference, San Juan, Puerto Rico

• 2007, S A C N A S Conference, Kansas City, Missouri

• 2007, XVIII MIE Undergraduate Research Symposium, MIE Program at UMET, San Juan, Puerto Rico

• 2006, ARVO Annual Meeting, Ft. Lauderdale, Florida

• 2006, Research Poster Symposium, Arizona State University, Tempe, Arizona

• 2006, XVII MIE Undergraduate Research Symposium, MIE Program at UMET, San Juan, Puerto Rico

• 2006, MIE Dissemination Conference, Bowie, Maryland

• 2006, SACNAS Conference, Tampa, Florida

• 2005, SACNAS Conference, Denver, Colorado

• 2005, XVI MIE Undergraduate Research Symposium, MIE Program at UMET, San Juan, Puerto Rico

PUBLICATIONS

Juan L Lequerica, Enrique J Berjano, Maria Herrero, Lemuel Melecio and Fernando Hornero. (2008). A cooled water-irrigated intraesophageal balloon to prevent thermal injury during cardiac ablation: experimental study based on an agar phantom Phys. Med. Biol.53(4), N25-34.

Melecio Rodríguez LF, Hernandez J, Pérez-Mayoral J, Molina AS, Carlo Chévere VL, Rodriguez LM, Cruz-Correa M. Planning for the unexpected: Strategies for maintaining a robust clinical trial program. Contemp Clin Trials Commun. 2020 Aug 20;19:100645. doi: 10.1016/j.conctc.2020.100645. PMID: 32913917; PMCID: PMC7471617. 6

News Articles:

Article: Desde Puerto Rico se prueba lo que podría ser la primera vacuna contra la hepatitis C. Publication: Medicina y Salud Publica, Digital Magazine Link: http://www.medicinaysaludpublica.com/desde-puerto-rico-se-prueba-lo-que-podria- ser-la-primera-vacuna-contra-la-hepatitis-c-2/

Article: In the Wake of Hurricane Maria, Mayo Clinic Clinical Trials Carry On in Puerto Rico. Publication: In the Loop: News and views from across Mayo Clinic Link: https://intheloop.mayoclinic.org/2017/11/14/in-the-wake-of-hurricane-maria-mayo- clinic-clinical-trials-carry-on-in-puerto-rico

Contact this candidate