Curriculum Vitae

Dr. John Jose E

Fellowship (Interventional & structural Cardiology, Germany), DM (Cardiology), MD (General Medicine)

Professor (Cardiology)

Christian Medical College Hospital Vellore-632004, India Mobile : +919*********

E mail : adg2se@r.postjobfree.com, adg2se@r.postjobfree.com Academic Qualifications:

• European Association of Percutaneous Cardiovascular Interventions (EAPCI) awarded training Fellowship in Interventional, endovascular and structural Cardiology-2014-15: Heart Center, Segeberger Kliniken (Academic teaching hospital of Universities of Kiel, Luebeck and Hamburg), Germany

• Advanced training in structural heart interventions at University heart center, Leipzig, Germany- 2018

• M.B.B.S:1996-2001, MD (Medicine)-2007, DM (Cardiology)-2011: Christian Medical College Vellore, India

Professional Affiliations:

• European Association of Percutaneous Cardiovascular Interventions, European Society Of Cardiology

• Cardiology Society Of India

Professional Experience:

• Professor, Cardiology 2017, Christian Medical College Hospital Vellore till present

• Physician/Adjunct Professor, Cardiology 2016, Christian Medical College Hospital Vellore

• Interventional Cardiologist, 2014-2015, Segeberger Kliniken GmbH, Germany

• Associate Professor, Cardiology 2013, Christian Medical College Hospital Vellore

• Assistant Professor, Cardiology 2011-2013, Christian Medical College Hospital Vellore

• Senior Resident, Cardiology 2007-2011, Christian Medical College Hospital Vellore

• Resident, Internal Medicine 2004-2007, Christian Medical College Hospital Vellore Experience and area of expertise: Interventional Cardiology experience of more than 10 years.

• Area of expertise: Trans catheter aortic valve implantation, transcatheter mitral valve-in-valve implantation, transcatheter pulmonary and tricuspid valve implantation, other structural heart interventions including valvuloplasties, device closure of left atrial appendage, ruptured sinus of Valsalva aneurysm, ASD, PFO, VSD and PDA, diagnostic coronary and peripheral angiogram including OCT, IVUS, iFr, FFr assessment, complex coronary and peripheral angioplasty including rotablation, use of peripheral atherectomy system, use of cerebral embolectomy devices, IABP and Impella circulatory assist system, endovascular repair of aneurysms, vena caval filter deployment.

• Started the percutaneous heart valve implantation program (TAVI) at CMCH Vellore. Performed the first transcatheter heart valve replacement with self-expanding and balloon expandable valves at CMCH Vellore, 2017.

• Proctor for transcatheter aortic valve implantation. Area of interest: Structural heart and aortic valve interventions Awards, prizes, accomplishments:

Cardiology

• Initiated the percutaneous heart valve implantation program (TAVI) at Christian Medical College Hospital Vellore.

Performed the first transcatheter heart valve replacement with self-expanding and balloon expandable valves at Christian Medical College Hospital Vellore, 2017

• Performed the first transcatheter pulmonary valve implantation

• European Association of Percutaneous Cardiovascular Interventions (EAPCI) interventional cardiology grant recipient, 2014

• One of the selected winners of the ‘Fellows got Talent’ at at The Transcatheter Cardiovascular Therapeutics (TCT) conference, San Francisco, USA 2015

• IABP Scholarship Case Winner at The Transcatheter Cardiovascular Therapeutics (TCT) conference, San Francisco, USA 2013

• Presenter of the best challenging case award at National Interventional Council meet in Cardiology, Kochi, 2014

• BBraun Medical Trust Foundation Scholarship Award in Cardiology, 2009

• I.P. Sukumar Memorial Award 2000

Medicine

• Dr. J.C.M Shastri Award, M.D. General Medicine, CMCH Vellore

• First Prize winner of ENDO-QUIZ, Winter Symposium on Endocrinology, Vellore, 2007

• First Prize winner of Chest Medicine Quiz by Respiratory Research Foundation, Chennai

• Dr.Niyamathullah Memorial Gold Medal and first Prize in 2007, Indian Society of Nephrologists Annual Conference, Hyderabad,

• Dr.Niyamathullah Memorial 2nd Prize winner in 2006, Indian Society of Nephrologists Annual Conference, Trivandrum

Research

• Primary on-site investigator for the multicenter Myval transcatheter heart valve trial

• Primary on-site investigator for the multicenter HYDRA transcatheter heart valve trial

• Primary on-site investigator and collaborator for multicenter the ISCHEMIA-CKD trial Publications:

1. Clinical bioprosthetic heart valve thrombosis after transcatheter aortic valve implantation: incidence, characteristics and treatment outcomes. John Jose, Dmitriy S. Sulimov, Mohamed El-Mawardy, Takao Sato, Abdelhakim Allali, Erik W. Holy, Björn Becker, Martin Landt, Julia Kebernik, Bettina Schwarz, Gert Richardt, Mohamed Abdel-Wahab. JACC cardiovascular Interventions 2017; 10(7):686-97.

2. Redo TAVI: initial experience at two German centres. Schmidt T1, Frerker C, Alessandrini H, Schlüter M, Kreidel F, Schäfer U, Thielsen T, Kuck KH, Jose J, Holy EW, El-Mawardy M, Allali A, Richardt G, Abdel-Wahab M. EuroIntervention. 2016 Sep 18;12(7):875-82. 3. 1-Year Outcomes After Transcatheter Aortic Valve Replacement With Balloon-Expandable Versus Self-Expandable Valves: Results From the CHOICE Randomized Clinical Trial. AbdelWahab M, Neumann FJ, Mehilli J, Frerker C, Richardt D, Landt M, Jose J, Toelg R, Kuck KH, Massberg S, Robinson DR, El-Mawardy M, Richardt G; CHOICE Investigators. J Am Coll Cardiol. 2015 Aug 18;66(7):791-800.

4. Transfemoral TAVI devices: design overview and clinical outcomes. Abdel-Wahab M, Jose J, Richardt G. EuroIntervention. 2015 Sep;11 Suppl W:W114-8. doi: 10.4244/EIJV11SWA33. 5. Setting up a transcatheter aortic valve implantation program: Indian perspective. Jose J, Manik G, Abdel-Wahab M. Indian Heart J. 2016 Sep - Oct;68(5):732-736. 6. Balloon- or Self-Expandable TAVI: Clinical Equipoise? Jose J, Richardt G, Abdel-Wahab M. Interventional Cardiology Review, 2015;10(2):103–8. 7. MY APPROACH to Management of Aortic Stenosis in the Elderly. Richardt G, Jose J. Practice Update Cardiology July 2015

8. Safety and Efficacy of Left Atrial Appendage Closure with the Amplatzer Cardiac Plug in Very High Stroke and Bleeding Risk Patients with Non-Valvular Atrial Fibrillation. Kebernik J, Jose J, Abdel-Wahab M, Stöcker B, Geist V, Richardt G. Cardiol Ther. 2015 Dec;4(2):167- 77. doi: 10.1007/s40119-015-0053-z. Epub 2015 Nov 13. 9. Effect of strut distribution on neointimal coverage of everolimus-eluting bioresorbable scaffolds: an optical coherence tomography study. Takao Sato, John Jose, Abdelhakim Allai, Mohamed El-Mawardy, Ralph Tölg, Gert Richardt & Mohamed Abdel-Wahab. J Thromb Thrombolysis. DOI 10.1007/s11239-017-1511-3

10. Comparison of Bailout and Planned Rotational Atherectomy for Heavily Calcified Coronary Lesions: A Single-Center Experience. Allali A, Abdel-Wahab M, Sulimov DS, Jose J, Geist V, Kassner G, Richardt G, Toelg R. J Interv Cardiol. 2017 Apr;30(2):124-133 11. Neointimal response to everolimus-eluting bioresorbable scaffolds implanted at bifurcating coronary segments: insights from optical coherence tomography. Sato T, Jose J, El-Mawardy M, Sulimov DS, Tölg R, Richardt G, Abdel-Wahab M. Int J Cardiovasc Imaging. 2017 Feb;33(2):169-175

12. Predictors of acute scaffold recoil after implantation of the everolimus-eluting bioresorbable scaffold: an optical coherence tomography assessment in native coronary arteries. Sato T, Jose J, El-Mawardy M, Sulimov DS, Tölg R, Richardt G, Abdel-Wahab M. Int J Cardiovasc Imaging. Int J Cardiovasc Imaging. 2017 Feb;33(2):145-152. 13. Relationship between peri-strut low intensity areas and vascular healing response after everolimus-eluting bioresorbable scaffold implantation: An optical coherence tomography study. Sato T, Jose J, El-Mawardy M, Sulimov DS, Tölg R, Richardt G, Abdel-Wahab M. J Cardiol. 2016 Aug 9. pii: S0914-5087(16)30146-0.

14. Testosterone as a marker of coronary artery disease severity in middle aged males. Gururani K, Jose J, George PV. Indian Heart J. 2016 Dec;68 Suppl 3:S16-S20. 15. Neointimal coverage of overlapping everolimus-eluting bioresorbable scaffolds: An optical coherence tomography study in native coronary arteries. Sato T, Jose J, El-Mawardy M, Sulimov DS, Tölg R, Richardt G, Abdel-Wahab M. Int J Cardiol. 2016 Oct 15;221:243-5. 16. Follicular thyroid carcinoma with tumour thrombus extending into superior vena cava and right atrium – A case report. Geetesh Manik, John Jose, B. Hygriv Rao. Manik G, Jose J, Hygriv Rao B. Indian Heart J. 2016 Sep;68 Suppl 2:S146-S147. 17. Transjugular balloon mitral valvotomy in a patient with inferior vena-caval interruption. Jose J, Kumar V, Joseph G. JACC CardiovascInterv. 2012 Feb;5(2):243-4. 18. Infective Endocarditis presenting with ST segment elevation. Jose J, Narayanan K, Chacko ST, George OK. J HeartValveDis. 2011 Jul;20(4):468-70. 19. Assessment of right ventricular strain and strain rate in patients with severe mitral stenosis before and after balloon mitral valvuloplasty. Kumar V; Jose VJ; Pati PK; Jose J: Indian Heart J. 2014 Mar-Apr;66(2):176-82

20. L Wave in Echo Doppler. Kumar V; Jose J; Jose VJ. Indian Heart J. 2014; 66(3):392-3 21. Profile of incident chronic kidney disease related-mineral bone disorders in chronic kidney disease Stage 4 and 5: A hospital based cross-sectional survey. A. T. Valson, M. Sundaram, V. G. David, M. N. Deborah, S. Varughese, G. Basu, A. Mohapatra, S. Alexander, J. Jose, J. Roshan, B. Simon, G. Rebekah, V. Tamilarasi, C. K. Jacob. Indian J Nephrol. 2014 Mar;24(2):97-107

22. High-Dose Statin Therapy in Asians: Not as Relevant as in Western Populations. V Jacob Jose, PK Pati, John Jose. Journal of Clinical and Preventive Cardiology, January 2012, Number 1

23. Intracardiac blood-filled cysts of the heart: a rare cause of embolic stroke. Jacob JJ, Jose J, John B. Singapore Med J. 2007 May;48(5):e125-6.

24. MycophenolateMofetil in Neuropsychiatric Systemic Lupus Erythematosus. J.Jose, B.K. Paulose, Z. Vasuki, D. Danda. Indian J Med Sci, Vol. 59, No. 8, August 2005. 25. Abstracts from the World Congress of Cardiology Scientific Sessions: Oral Presentations From the WORLD CONGRESS OF CARDIOLOGY Scientific Sessions 2012: Dubai, United Arab Emirates18–21 April 2012 Circulation. 2012;125:e659-e740 26. Postprandial angina: not always due to stenotic coronary artery disease. Ghosh GC, Jose J, George PV. BMJ Case Rep. 2017 Nov 3;2017. pii: bcr-201*-******. doi: 10.1136/bcr-2017- 223030.

27. Anomalous left coronary artery from pulmonary artery as a rare cause for exertional angina in a young wife. Ghosh GC, Jose J, Gururani K. Heart Views (In print) Conference Presentations/Faculty role

• Faculty and speaker, India Live 2019

• Faculty Cardiovascular therapeutics conference 2018

• Faculty India Valves 2017, 2018

• Accepted case abstracts- Euro PCR 2020, TCT-USA 2019, Asia-PCR 2017, PCR London valves 2017, CCT Kobe 2016

• OCT guidance for left main bifurcation PCI- KI Imaging, Korea 2016

• Valve thrombosis after trancatheter aortic valve replacement: incidence, characteristics and outcomes (TCT 2015)

• TAVI in a patient with degenerated stentless aortic bioprosthesis(TCT 2015)

• Relationship between the degree of device oversizing and clinical outcomes in patients treated with transcatheter aortic valve replacement using balloon-expandable or self-expanding valves: Insights from the randomized CHOICE trial (TCT 2015)

• Hemodynamic support with an Impella pump during percutaneous mitral valve repair using MitraClip in a patient with severe symptomatic mitral regurgitation, severe left ventricular dysfunction and recent acute myocardial infarction. (Challenging case TCT 2015)

• TAVI with PCI in a patient with degenerated stentless aortic bioprosthesis and re-implanted coronaries (PCR London Valves 2015)

• Transjugular Balloon Mitral Valvuloplasty in a Patient With Severe Scoliosis, EUROPCR 2014

• Treatment of type-3 endoleak following EVAR by translumbar cyanoacrylate glue injection and improvement of apposition between overlapping aortic stent-grafts by Palmaz stent deployment, NIC Mid-term meet Kochi, 2014

• IABP Scholarship Case, TCT 2013, San Francisco USA

• Correlates of functional tricuspid regurgitation in rheumatic mitral valvular disease by 2D and 3D echocardiography, European Society of Echocardiography, Euro ECHO Imaging, Istanbul, Turkey, 2013

• Endovascular treatment of thoracic aorta, 5

th

Asia Pacific Vascular Society Summit, 2013,

New Delhi

• Coronary Artery Disease & Diabetes Mellitus, Distance Education Fellowship in Diabetes Management (DFID) Course Lecture, 2013 & 2014, Vellore

• Percutaneous retrieval of dislodged Atrial Septal Occluder device. Structural Heart Disease Case, NIC Mid-term meet, 2013

• Percutaneous intervention for totally occluded Aortic Co-arctation, TCT-AP, 2013, Seoul, Korea

• Determinants of functional TR severity. World Congress Of Cardiology 2012, Dubai, UAE Interests: TAVI; structural, endovascular and peripheral interventions, complex coronary interventions, clinical research

John Jose E Date of birth: 19-5-1979 Languages: English, German, Hindi, Malayalam, Tamil Professor, Department Of Cardiology, Christian Medical College Hospital, Vellore

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