*

CURRICULUM VITAE

RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P.

EDUCATION: Oberlin College - Oberlin, Ohio - A.B. 1961 Ohio State University - Columbus, Ohio - M.D. 1965 University of Oriental Studies - Monterey Park, Ca. – Ph.D., Acupuncture, 1983

PROFESSIONAL TRAINING:

1965-1966 Internship - Maumee Valley Hospital - Toledo, Ohio 1966-1968 Resident - Internal Medicine - Maumee Valley Hospital Jan-Jul 1969 Toledo Hospital - Nephrology - Toledo, Ohio Jul-Dec 1969 Resident - Internal Medicine - Maumee Valley Hospital - (Chief Resident)

Jan-Feb 1970 Cleveland Clinic - Nephrology-Hypertension - Cleveland, Cleveland, Ohio

Sep 1971 UCLA - Dr. Paul Terasaki's Tissue Typing Lab - Los Angeles, California

APPOINTMENTS:

1965 Active Staff- Medical College Hospital - Toledo, Ohio Jan 1969 Consulting Staff- Toledo Hospital - Toledo, Ohio Jan 2019 Emeritus Staff

Feb 1970 Instructor - Medical College of Ohio - Toledo, Ohio CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 2

APPOINTMENTS (Continued):

Feb 1970 Director- Hemodialysis Unit - Medical College Hospital- Toledo, Ohio

Feb 1970-2002 Active Staff - Riverside Hospital - Toledo, Ohio Hospital closed

2002-2018 Consulting Staff, Mercy St. Anne Hospital, Toledo, OH 2019 Emeritus Staff

Feb 1970 Medical Advisory Board- Northwestern Ohio Kidney Foundation (Chairman- 1974)

Dec 1970 - Director- Hemodialysis Unit - Toledo Health & Retiree Jul 1972 Center, Toledo, Ohio

Jul 1970- Director - Hemodialysis Unit - Medical College of Ohio Jan 1981 Toledo, Ohio

Jan 1971-75 Coordinating Committee - State of Ohio Renal Disease Mar 1971 Reference Panel Chairman - Regional Medical Program Northwestern Ohio Renal Disease

Sep 1971-Aug. 1976 Assistant Professor of Medicine Medical College of Ohio Toledo, Ohio

Oct 1971-74 Director- Northwestern Ohio Regional Tissue Typing Laboratory

1973-2019 Consulting Staff, The Toledo Hospital, Toledo, Ohio Jun1973-2014 Consulting Staff- St. Luke's Hospital - Toledo, OH 2014- 2018 Affiliate Staff

2019 Resigned

Sept. 1973-78 Director - Total Renal Care Unit - Medical College Hospital Toledo, Ohio

CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 3

APPOINTMENTS (Continued):

June 1975-1995 Active Staff- Mercy Hospital - Toledo, Ohio Co-Director of Acute Hemodialysis and Renal Program

1995 Hospital Closed

Jun 1975-2014 Courtesy Staff- Flower Hospital - Toledo, Ohio July 2014 Affiliate Staff

Sept 1976- Apr 1981 Associate Professor of Medicine - Medical College of Ohio -Toledo, OH Apr 1981 Private Practice – Nephrology/ Internal Medicine/ Pain Control- Toledo, Ohio

Apr 1981- Associate Clinical Professor of Medicine - Medical College of Ohio - Toledo, Ohio

Aug 1981-1984 Medical Director- Symedix/Symed Care - Dialysis Facility Toledo, Ohio

Jan 1982 Courtesy Staff- St. Vincent Hospital - Toledo, Ohio 1983-2018 Consulting Staff

2018 Emeritus Staff

1982 Consulting Staff - St. Charles Hospital - Oregon, Ohio 1993- Active Staff;

2014 Emeritus Staff

Sep 1982-1990 Consulting Staff- Parkview Hospital - Toledo, Ohio 1990 Hospital Closed

1984-1997 Co-Director - Greenfield Dialysis Facility - Toledo, Ohio 1996-2001 Co-Director – Acute Hemodialysis Unit, Riverside Hospital – Toledo, Ohio

1996-2001 Co-Director – Gambro Healthcare Dialysis Facility – Toledo, Ohio

2001-2004 Commissioner – Education and Professional Affairs Commission, The Academy of Medicine of Toledo & Lucas County

CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 4

APPOINTMENTS (Continued):

2005- Commissioner – Community Relations Commission, The Academy of Medicine of Toledo & Lucas County,

2006- Chairman

Oct. 2001-2018 Courtesy Staff - Bay Park Community Hospital, Oregon, Ohio 2018 Affiliate Staff 2018

Aug. 2002-2018 Consulting Staff – Mercy St. Anne Hospital, Toledo, Ohio 2018 Emeritus Staff

May 1988-Jan 1999 Advanced Medical Technology, Medical Director June 1993-2000 Edok.Com, Medical Director

2000 Company Dissolved

Jan. 2000 Physician’s Technology LLC, Medical Director, Monroe MI and Toledo, OH

May 2018 Willow Labs, LLC, Medical Director Monroe, MI April 2009-2013 Director Interval Pain Service – Mercy St. Anne Hospital, Toledo, Ohio

May 2009-2016 Director Continuing Medical Education – Mercy St. Anne Hospital, Toledo, Ohio

May 2015-2018 Co-Director Continuing Medical Education-Mercy Health, Northern Region

Oct. 2012 Reviewer–Journal of Musculoskeletal Pain Feb. 2014 Board of Directors, New Christy Minstrels Foundation MILITARY:

Sep 1966-72 Captain - U.S. Army Reserve - Medical Corps, Honorably Discharged 1978

CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 5

MEDICAL LICENSE:

Ohio #28311

Michigan #28590 (inactive)

California #C28752 (inactive)

Florida #ME0042988 (inactive)

SOCIETIES AND COMMITTEES:

1970-71 Co-Chairman - Renal Electrolyte Phase of Medical Students Medical College of Ohio - Toledo, Ohio

1972-Committee Member

Jan 1971 American Society of Nephrology

Jan 1972 International Society of Nephrology

Jul 1973 American Heart Association - Council on the Kidney 1974- American Federation for Clinical Research

1975 Fellow, The Academy of Medicine of Toledo and Lucas County 1975-2002 The Ohio State Medical Association

1976 American College of Physicians

2007 Fellow American College Physicians

1976 American Association of Tissue Banks

1976 American Society of Internal Medicine

1977-81 American Association of University Professors 1978-79 Network #22 - Medical Review Board

1978-1988 US Renal Physicians Association

1981 Network #22 - Coordinating Council - Medical College of Ohio - Alternate

1982-2017 The American Association of Acupuncture and Oriental Medicine

1983-1992 Center for Chinese Medicine

1986-2005 International Veterinary Acupuncture Society CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 6

SOCIETIES AND COMMITTEES (Continued):

1991- American Academy of Medical Acupuncture

1994-2001 Acupuncture Society of Michigan

1997-2007 Mercy Health Partners, Regional Task Force on Complementary and Alternative Medicine

2001-2004 The Academy of Medicine of Toledo and Lucas County, Education and Professional Affairs Commission.

2005-2018 The Academy of Medicine of Toledo and Lucas County, Community Relations and Communications, Chairman

2018 Organization Paused

2003-2009 Advisory Committee, Therapeutic Massage Program, Mercy College of Northwest Ohio

2007- Midwest Pain Society

AWARDS:

1970, 1973, 1976 Physicians Recognition Award for Continuing Education 1974 Comprehensive Health Planning Award for Outstanding Contributions and Planning for Kidney Disease in Northwest Ohio

1976 Physicians Award - Ohio State Medical Association 1979 Medical Award - Northwestern Ohio Kidney Foundation 0ct 1984 Doctor of Science - Medicina Alternativa - Sri Lanka CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 7

AWARDS (Cont.):

1990 Honorary Advisor International Academy of

Scientific Acupuncture, Dadar, Bombay

1994, 1995 American Academy of Family Physicians, Recognition as an Active Teacher in Family Practice

2007 Fellowship, American College of Physicians (FACP) PATENTS:

U.S. Patent number: 5,024,236 Photoprobe Assembly

U.S. Patent number: 6,187,029 Photo-Thermal Device

U.S. Patent Application Serial No. 11/437,070 Photo-Thermal Therapeutic Device

U.S. Patent Application No.: 13/462,528 Photonic and Thermal Kinetic Energy Therapeutic Device, System and Method.

U.S. Patent 649,257 Photo Thermal Therapy Device and Charging Dock Station

U.S. Patent 634,708 Charging Docking Station for Photo Thermal Therapy Device

U.S. Patent 650,486 Photo Thermal Therapy Device

U.S. Patent Smart Laser Bio-Sensor and Bio-Therapeutic Device System and Methods, issue date 6.2.15

CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 8

COMPANY POSITIONS:

EQUINE PAIN CONTROL, LTD.

1986 – 2002 President

Complementary Medicine techniques in horses for pain control, healing, and rehabilitation

ADVANCED MEDICAL TECHNOLOGY, INC

1987-1995 Vice President of Research, Development, and Promotion of Alternative Health Technology

PHYSICIANS TECHNOLOGY, LLC

1995-2000 Vice President of Medical Research and Clinical Application 2000- Medical Director

EDOK.COM, LLC Medical Director

1998-2004-

2000- PHYSICIAN’S TECHNOLOGY LLC, WILLOW CURVE

Medical Director

2018 WILLOW LABS, LLC, MEDICAL DIRECTOR

CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 9

PUBLICATIONS:

1. Woodson RD., Shapiro RS, Single and Multiple Mechanically Stapled Arteriovenous Fistula for Chronic Hemodialysis -. - Abstracts - American Society of Nephrology-, Nov 1971.

2. Shapiro RS, Woodson, RD, Preservation of Vessel Access for Chronic Hemodialysis. Dialysis & Transplantation, Vol. 2, No. 6, Oct 1973; 48-51. 3. Woodson, RD, Shapiro, RS., Antegrade Vs. Retrograde Fistula Cannulation - - Dialysis & Transplantation, Vol.3, No. 2, February/March 1974; 29-30. 4. Woodson, RD, Shapiro, RS, Vascular Access for Hemodialysis: 3 Years Experience with Mechanically Stapled Arteriovenous Fistulae - - Abstracts American Society of Nephrology, Nov 1973.

5. Shapiro RS, Woodson RD, Bartholomay AF The Use of Activated Partial Thromboplastin Time to Monitor Anticoagulation in Uremic Patients Undergoing Hemodialysis - Dialysis & Transplantation, Apr 1975; 56-58. 6. Vetter L, Shapiro RS, An Approach to Dietary Management of the Renal Patient- - Journal of the American Dietetic Association, Feb 1975; 158-62. 7. Shapiro RS, A Home-Made Method for Peritoneal Dialysis in the Neonate. Journal of Pediatrics, Jan 1976; 160.

8. Bachmann K, Shapiro RS, MacKiewics J, Influence of Renal Dysfunction on Warfarin Plasma Protein Binding. Journal of Clinical Pharmacology, Vol. 16, No. 10, Oct 1976; 468-72.

9. Shapiro RS., Desmukh, A, Kropp KA, Massive Proteinuria After Live Donor Renal Transplantation: Biopsy Proven Nil Disease. Transplantation, Vol. 22, No. 5, Nov. 1976; 489-92.

10. Shapiro RS., Gunning WT, Kropp KA., Identification of Adequate Renal Tissue at the Time of Biopsy. Journal of Dialysis & Transplantation, Jun 1977; 46, 72. 11. Kropp KA, Jhunjhunwala J, Shapiro RS, Unsuspected Primary Renal Tumor in Chronic Renal Failure, In preparation.

12. Bachmann K, Shapiro RS, MacKiewics, J, Warfarin Elimination and Responsiveness in Patients with Renal Dysfunction. Journal of Clinical Pharmacology, Jun 1977; 292-9. 13. Bachmann K, Shapiro RS, Protein Binding of Coumarin Anticoagulants in Disease States

-Clinical Pharmacokinetics, 2:110-126, 1977; 110-26. CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 10

14. Tan SY., Shapiro RS., Franco., Stockard HE,, Mulrow PJ, Indomethacin - Induced Prostaglandin Inhibition with Hyperkalemia: A Reversible Cause of Hyporeninemic Hypoaldosteronism. Clinical Research, Vol. 25, No. 4, Oct 1977. 15. Tan SY, Shapiro RS, Mulrow PJ, Renal Prostaglandins Exert Major Influence on the Renin-Aldosterone Axis and on Potassium Homeostasis. Clinical Research, Vol. 25, No. 4, Oct 1977.

16. Tan SY, Shapiro RS, Mulrow P.J., Renal Prostaglandins Exert Major Influence on the Renin-Aldosterone Axis and on Potassium Homeostasis. Abstracts - The American Society of Nephrology, Nov 1977.

17. Kropp KA, Shapiro R.S, Jhunjhunwala J, Role of Renal Biopsy in End Stage Renal Failure. Urology, Vol. XII, No. 6, Dec 1978; 631-4.

18. Bachmann K, Conway P, Shapiro R S, Inability of Retained Metabolites of Uremia to Alter the Extent of Warfarin Binding in Charcoal Treated Plasma. Research Communications in Chemical Pathology and Pharmacology, Vol. 20, Feb 1978;117-30. 19. Jhunjhunwala J, Shapiro RS, Kropp K, Morbidity and Mortality Associated with Retained Homograft After Discontinuation of Immunosuppression. Paper withdrawn from submission.

20. Tan SY, Shapiro RS, Kish MA, Reversible Acute Renal Failure Induced by Indomethacin. JAMA, Vol. 241, No. 25, Jun 1979; 2732-3.

21. Tan SY, Shapiro RS, Franco R, Stockard, HE, Mulrow,PJ, Indomethacin - Induced Prostaglandin Inhibition with Hyperkalemia: A Reversible Cause of Hyporeninemic Hypoaldosteronism. Annals of Internal Medicine, Vol. 90, No. 5, May 1979;783-5. 22. Tan SY, Shapiro RS, Antonipillai I, Mulrow P.J, Big Renin in Diabetics with Nephropathy. Abstracts - Western Dialysis and Transplant Society, 1978. 23. Shapiro RS, Antonipillai I, Mulrow PJ. Adverse Renal Effects of Non-Steroidal Anti- Inflammatory Drugs (NSAID). Abstracts - Western Dialysis & Transplant Society, 1978. 24. Bachmann K, Shapiro RS., Fulton R, Caroll T, Sullivan T, Smoking and Warfarin Disposition. Journal of Clinical Pharmacology & Therapeutics, Mar 1979; 309-15. 25. Amrutha,B, Bree, R, Shapiro RS, Kuebbeler P, The Pregnant Renal Transplant Patient- Ultrasound to Aid in the Choice of Delivery Mode. Dialysis & Transplantation, Vol. 8, No. 9, Sep 1979; 910.

26. Shapiro RS, Bachmann K, A Suggestion for Measuring Non-Smoking Compliance. paper withdrawn from submission.

CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 11

27. Kaiser L, Kelly TJ, Patterson MJ, Sanchez T, Shapiro RS, Mayor G, Hepatitis B Surface Antigen in Urine of Renal Transplant Recipient. Annals of Internal Medicine, Vol. 94, No. 6, Jun 1981; 783-4.

28. McLeish K, Gohara A, Shapiro R S, Massive Post Transplant Proteinuria with Minimal Change Histology. Transplantation, Jun 1980; 392-6. 29. Bachmann K, Valentovic M, Shapiro RS, A Possible Role for Cyanate in the Albumin Binding Defect of Uremia. Biochemical Pharmacology, Vol. 29, 1980; 1598-1601. 30. Skeel J, Shapiro R S, No More Dialysis: The "Right" Decision for the "Wrong" Reasons. Dialysis and Transplantation, Mar 1981; 190-2.

31. Kollarits CR, Shapiro RS, Swann ER, Roche R, Kollarits FJ, Effect of Hemodialysis on Selected Physical Ocular Parameters. Metabolic and Pediatric Ophthalmology, Vol. 5,1981; 73-76.

32. Suzuki S, Shapiro RS, Mulrow PJ, Tan SY, Urinary Prostaglandin E2 Excretion in Chronic Renal Disease. Prostaglandin Medicine, May 1980; 377-82. 33. Burhkart C, Shapiro RS, Pseudomonas Folliculitis: Occurrence After Home Use of Whirlpool Spa. Cutis, Jun 1980; 642-3.

34. Bachmann K, Valentovic M, Shapiro RS, The Contributions of Cyanate to the Albumin Binding Defect of Uremia. Biochemical Pharmacology, Vol. 30, 1981; 1059-1063. 35. Bachmann K, Shapiro RS, Forney R, Warfarin Binding to Plasma of Workers Exposed to Toluene Disocyanate . International Journal of Clinical Pharmacology, Therapy, and Toxicology, Vol. 20, No. 2, 1982; 47-50.

36. Somani P, Shapiro R S, Stockard H, Unidirectional Gentamicin Kinetics in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis. Clinical Research, Vol. 30, No. 2, 1982; A463-A463.

37. Somani P, Shapiro RS, Stockard H, Unidirectional Gentamicin Exchange Through the Peritoneal Membrane. Clinical Research, Vol. 30, No. 2, 1982; A463-463. 38. Swann E, Shapiro RS, Gillespie C, Shealy R, HLA AI and Steroid-Induced Cataracts in Renal Transplant Patients. Annals of Ophthalmology, Vol. 14, No. 12, Dec 1982; 1116- 1118.

39. Somami P, Simon V, Gupta RD, King P, Shapiro RS, Stockard H. Lorcainide Kinetics and Protein Binding in Patients with End-Stage Renal Disease. Journal of Clinical Pharmacology; International Journal of Clinical Pharmacology, Jan 1984; 121-125. CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 12

40. Somani P, Simon V, Shapiro RS, Gupta RD, Stockard HE, Pharmacokenitcs of Lorcanide in Patients Undergoing Hemodialysis. Clinical Research, Vol. 30, No. 4, 1982; A718- A718.

41. Shapiro RS, Stockard HE, Schank AS, Successful Treatment of Uremic Pruritus with Acupuncture. American Journal of Acupuncture, Vol. 14, No. 3, Jul-Sep 1986; 235-242. 42. Shapiro RS, ChristopherW, Cicora BJ, A Novel Approach to Equine Acupuncture and Healing. International Veterinary Acupuncture Newsletter, Mar 1986; 6. 43. Shapiro RS, Rapid, Effective, Non-Invasive Treatment of Pain and Disease. American Journal of Acupuncture, Mar 1987; 43-47.

44. Shapiro RS, LT-100 (Light Pen) Pain & Healing Therapy Made Simpler and Effective. International Society of Alternative Medicine, Vol. 2, No. 1., Nov 1987; 1-10. 45. Shapiro RS, Stockard HE, Schank A, Uremic Pruritus, Successfully Treated with Acupuncture. Dialysis & Transplantation, Vol. 17, No. 4, Apr 1988; 235-242. 46. Shapiro RS, Electroencephalographic Evidence Demonstrates Altered Brain Wave Pattern by Acupoint Stimulation. American Journal of Acupuncture, Vol. 17, No. 1, Jan- Mar 1989; 25-29.

47. Shapiro, RS, Christopher W, Cicora BJ, Effective Stimulation of Auricular and Body Acupuncture Materials. Veterinary Acupuncture Newsletter, Vol. 14, No. 1, Jan-Mar 1988; 25-26.

48. Shapiro RS, Acupuncture Without Needles for Drug Detoxification and Substance Withdrawal. Submitted for publication.

49. Shapiro RS, An Innovative Aid to Augment Complementary Medicine Techniques. American Chiropractor, Aug 1988.

50. Shapiro RS, Diminution of Electroencephalographic Muscle Tremor Artifact. Journal of Intensive Care Medicine, Vol. 4, No. 5, Sep-Oct 1989; 234-235. 51. Shapiro RS, A Dramatic Therapeutic Possibility in the Management of Rheumatoid Arthritis. American Journal of Acupuncture, Vol. 17, No. 3, Jul-Sep 1989; 211-214. 52. Shapiro RS, Shall S, Ziegler R, Dunlap R, Phototherapy to Accelerate Healing and Pain Control in Post Dental Surgical Patients. In preparation. 53. Shapiro RS, Deshetler N, Stockard HE, Fluid Overload Again! - A Technique to Enhance Fluid Compliance. Dialysis and Transplantation, Vol. 23, No. 6, June 1994; 303-305. CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 13

54. Shapiro RS, Ayers MA Human Electroencephalographic Evidence of Relaxation From Cutaneous Stimulation -.- Paper withdrawn from submission. 55. Drake DA, Shapiro RS, Ayers MA, Equine Relaxation from Cutaneous Stimulation,

"Electroencephalographic Documentation." Paper withdrawn from submission. 56. Bachmann K, Sullivan TJ, Reese JH, Jaurequi L, Miller K, Scott M, Sides D, Shapiro RS, The Influence of Dirithromycin on the Pharmacokinetics of Cyclosporin in Healthy Subjects and in Renal Transplant Patients. American Journal of Therapeutics 2,1995; 490-497.

57. Shapiro RS, Simple and Effective Management of Rheumatoid Arthritis - An Alternative Approach for Physicians. Medical Acupuncture, – Vol 9, No. 1, Spring/Summer 1997; 26-31.

58. Shapiro RS, Alternative Measures for The Older Adult,., by invitation to be published in Handbook in Caring for Older Adults. Ed. McGreevy, Steiner, V, and McMillen W, Medical College of Ohio Press, Toledo, 1998.

59. Seegert E M, Shapiro R S, The Effects of Alternative Exercise on Posture. Clinical Kinesiology, Vol. 53, No. 2, Summer 1999; 41-47.

60. Shapiro RS, Stockard, HE, Successful Treatment of Uremic Puritus: The Acupuncture Approach Revisited, Dialysis and Transplantation, Vol 32, No 5, May 2003. 61. Shapiro R S, An Innovative Technique for Relief of Knee Pain. The American Academy of Medical Acupuncture, Vol. 15, No. 2, January 2004. 62. Shapiro RS, Knee Pain: A Potential Treatment Dilemma. The Academy Corner, Healthy Living News, February 2005, 47-48.

63. Shapiro RS, Bachmann K, Dunlap RC, Safe and Effective Relief of Knee Pain for the Patient with Renal Insufficiency and Renal Failure - New Technology. Dialysis and Transplantation, Vol. 34, No. 11; November 2005, 758-766.

64. Shapiro RS, Doctor, My Knee Hurts, The Academy Corner, Healthy Living News, August 2007.

65. Shapiro RS, A Quick Fix for Hot Flashes. Medical Acupuncture, July 2008.

66. Shapiro RS, New Technology for Safe and Effective Pain Relief. The Academy Corner, Healthy Living News, July 2008

CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 14

67. Shapiro RS, Do you have Toxic Joint Syndrome? Healthy Living News, September, 2011, 15-19.

68. Shapiro RS, Bertrand CA, Chelucci KM, Davis KR, Thaxton LL, Relief from Toxic Joint syndrome in CKD Patients- A New Therapeutic Option. Submitted for publication, 2011.

69. Shapiro RS, Bertrand CA, Are You Plagued with Toxic Joint Syndrome?, Medicine Up To The Minute, http://www.medicineuptotheminute.com/, December, 2011. 70. Shapiro RS, Thaxton LL, Bertrand, CA, Chelucci, KM, Davis, KR, Fadell, Toxic Joint Syndrome – Characterization with a New Therapeutic Option. Monograph published by Physician’s Technology, 2012, http://www.willomd.com. 72. Shapiro R S, Bertrand CA, Toxic Joint syndrome – A New therapeutic Option. Medicine Up To The Minute, http://www.medicineuptotheminute.com/, Jan. 2012. 73. Shapiro RS, Sutton DB, Take a Billion Pain Pills off the Market. Medicine Up To The Minute, http://www.medicineuptotheminute.com/, May 2012. 74. Chelucci KM, Shapiro RS, Bachmann K, White D, Clinical Evaluation of a Non-Invasive Technology for the Treatment of Chronic Joint Symptoms. Journal of Orthopedic Research and Review. Vol. 2013:5, January 2013; 5-11. 75. Shapiro RS, Sutton DB, Exploring New Options for Pain Management, fighting the opioid epidemic. Home Care Magazine.

http://www.homecaremag.com/hme-products-pain-management/exploring-new- options-pain-management, Sept. 2016.

76. Shapiro RS, Sutton DB A Discussion of the Scientific Aspects of Smart Laser Technology, submitted for publication, Jan. 2019.

CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 15

PAPERS AND PRESENTATIONS

1. Vessel Access for Chronic Hemodialysis - Mar 31, 1971 - Toledo Surgical Society - Toledo, Ohio.

2. Single and Multiple Mechanically Stapled Arteriovenous Fistulae for Chronic Hemodialysis - Nov 23, 1971 - The American Society of Nephrology. 3. Dietary Requirements in Renal Disease - Apr 5, 1973 - The Ohio State Dietetic Association.

4. Normal Blood Tests - No Assurance of Normal Renal Function - Oct 31, 1973 - Northwestern Ohio Dietary Association.

5. Renal Problems in Vascular Surgery, and Temporary Supportive Measures - Apr 19, 1975 - American College of Surgeons, Emergency Medical Services, N.W. Ohio, Problems in Vascular Surgery.

6. Chronic Renal Failure - Sep 3, 1975 - Northwestern Ohio Dietetic Association. 7. Acute and Chronic Renal Failure - Nov 8, 1975 - Ohio Student Nurse Association. 8. Renal Failure, Diagnosis and Treatment - Feb 25, 1976 - American Association of Critical Care Nurses.

9. Renal Function and Renal Failure, Problems in The Injured Patient, Trauma Workshop Apr 22-23, 1976 - American Trauma Society.

10. The Role of Renal Biopsy in End Stage Renal Failure - Kropp, K., Shapiro, R., Jhunjhunwala, J. - May 17, 1976 - American Urologic Association. 11. Unsuspected Primary Renal Tumor in Chronic Renal Failure - Kropp, K., Jhunjhunwala, J., Shapiro, R. - May 20, 1976 - American Urologic Association. 12. The Role of Renal Biopsy in End Stage Renal Failure - Shapiro, R., Kropp, K., Jhunjhunwala, J. - Sep 18, 1976 - American College of Physicians, Ohio Regional Meeting and Ohio Society of Internal Medicine.

13. To Dialyze or Not to Dialyze: How and When? - Sep 29, 1976 - The American Trauma Society and Emergency Medical Services, Drugs, Abuse, Overdose and Management.

14. Morbidity and Mortality Associated with Retained Homograft After Discontinuation of Immunosuppression - Jhunjhunwala, J., Shapiro, R.S., Kropp, K. - Oct 1976 - 50th CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 16

Annual Meeting of North Central Section of American Urological Association in West Palm Beach, Florida.

15. Sodium Metabolism in the Brookhaven Salt Sensitive and Resistant Rat - Higgins, J., Shapiro, R., Stockard, H., Kim, G., Rapp, J. - Jun 4, 1977 - Annual Meeting of Midwestern Salt and Water Club.

16. Indomethacin Induced Prostaglandin Inhibition with Hyperkalemia: A Reversible Cause of Hyporeninetnic Hypoaldosteronism - Tan, S.Y., Shapiro, R., Franco, R., Stockard, H., Mulrow, P.J. - 1977- American College of Physicians - Ohio Regional Meeting. 17. Renal Prostaglandins Exert Major Influence on Renin-Aldosterone Axis and on Potassium Homeostasis- Tan, S.Y., Shapiro, R., Mulrow, P.J. - Nov 22, 1977 - American Society of Nephrology.

18. Innovations in the Treatment of Pain - Mar 27, 1985 - Riverside Hospital Toledo, Ohio

- Pain: Trends in Nursing Management.

19. Approach to Pain Management - Apr 23, 1985 - Toledo Dental Society Forum. 20. Alternative Medicine - Oct 1986 - Coors Brewing Company - Management and Wellness Team - Golden, Colorado.

21. Innovations in Pain and Behavior Control - Nov 1986 - State of Ohio Department of Health, Safety and Health Awareness for Public Employees. 22. Breakthrough in Therapy, with Photo and Magnetic Applications - Seminar Jun 1986 - M.E.D.S. Services -Kanata, Ontario.

23. Innovations in Pain Control and Wound Healing - Feb 1987 - West Central Kidney Foundation - Annual Meeting.

24. Complementary Medicine - A course presented at The Adolph Coors Company Medical Wellness Center, Golden, Colorado – Feb. 23-27, 1987. 25. Phototherapy: A Rapid Effective and Efficient Treatment of Pain and Diseases - Apr 2-5, 1987 - American Academy of Acupuncture Medicine (AAAM) - 13th Annual Seminar/Symposium on Acupuncture Auricular Medicine - San Francisco, California.

26. Pain Control and Wound Healing - Riverside Hospital Medical Staff Meeting - Toledo, Ohio - Apr 14, 1987.

27. Effective and Efficient Treatment of Pain and Diseases with Corimag Magnets - Pain, Healing and Addiction Symposium - Ottawa, Ontario Canada -Jun 12-14, 1987. CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 17

28. The 1st

Rib – Stellate Syndrome - Pain, Healing and Addiction Symposium Ottawa, Ontario Canada - Jun 12-14, 1987.

29. Innovations in Pain Control and Wound Healing and Behavior Modification- Findlay University - Findlay, Ohio - Feb 28, 1988.

30. Innovations in Pain Control and Wound Healing - Northwestern Ohio Self-Insurers Association - Sept 20, 1990.

31. Complementary Medicine Techniques for Wound and Pain Care - Emergency Medicine Grand Rounds - Toledo Hospital - Toledo, Ohio - Oct 1990. 32. Approach to Acute Renal Problems- Blanchard Valley Medical Staff - Shapiro, R., Berlacher, P., Perone, S. - Findlay, Ohio - Mar 1991. 33. Workshop: Acute Renal Failure - St. Charles Medical Staff- Toledo, Ohio Feb 1991. 34. The Vascular Autonomic Signal - Magnetic Therapy, Contemporary Innovations in Complementary Medicine - The Miami Acupuncture Center Miami, Florida - Mar 15, 1992.

35. Alternative Medicine - Positive Lifestyles, WFOB Radio, Fostoria, Ohio, Oct 14, 1993. 36. Alternatives in Pain Control and Wound Healing, University of Findlay, Equestrian College, Findlay, Ohio, April 22, 1994.

37. Renal / Electrolyte Workshop, The Toledo-Lucas County Academy of Medicine’s Winter Seminar, Puerto Vallatra, Mexico, January /February 1996. 38. Pain Management/Alternative Therapies, The Toledo-Lucas County Academy of Medicine’s Winter Seminar, Puerto Vallatra, Mexico, January /February 1996. 39. You Can Stop The Pain, A Spectrum of Complementary Diagnosis and Therapeutics, The University of Miami School of Medicine, Acupuncture In Action, Module III, Miami, Florida April 18-19, 1997.

40. Acupuncture and Other Techniques for Pain Management, Mercy Health Partners’ Conference on Integrative Medicine: Evaluating New Approaches to Mind/Body Health, Toledo, Ohio, April 16-17, 1999.

41. Alternative Medicine 2000, Riverside Mercy Hospital, Medical Staff Meeting, Toledo, Ohio, November 14, 2000.

CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 18

42. The Power of Digital Systems at Your Fingertips, Part I, “You can do it all”, Academy of Medicine of Toledo and Lucas County, Winter Seminar 2001, Costa Rica, January 27, 2001.

43. The Power of Digital systems at Your Fingertips, Part II, “You can do it all”, Academy of Medicine of Toledo and Lucas county, Winter Seminar 2001, Costa Rica, January 31, 2001.

44. The MedLite: Stop Pain and Speed Healing, Radio 92.5 Kiss FM Interview, Toledo, Ohio, February 22, 2001.

45. The Spectrum of Complementary and Alternative Medicine – Presentation and Workshop, Medical College of Ohio, Toledo, Ohio, Physician Assistant Humanities Course, March 23, 2001.

46. New Technology for Pain Relief, Devonshire at PGA National, West Palm Beach, FL, April 5, 2001.

47. PhotoThermal Therapy, New Technology for Pain Relief and Accelerated Healing, Medical College of Ohio, Toledo, Ohio, Department of Medicine, Medical Grand Rounds, May 3, 2001.

48. Renal and Electrolyte Workshop, St. Vincents Mercy Hospital, Toledo, Ohio, Department of Medicine Grand Rounds, May 16, 2001. 49. Acupuncture & PhotoThermal Therapy: New Technology to Stop Pain and Speed Healing; St. Charles Mercy Hospital Center for Health Promotion, Wellness Spa Day, Key Note speaker, Toledo, Ohio, June 21, 2001.

50. The Effects of Alternative Exercise on Posture, Seegert, E. M., Shapiro, R. S., The Feldenkrais Society, National Meeting, San Francisco, California, October 10, 2001. 51. The MedLite, an Alternative Approach to Pain Relief and Healing, R. Shapiro & R. Dunlap, Radio WSPD – Mark Standriff Interview, Toledo, Ohio, December 19, 2001. 52. New Technology for Pain Relief and Healing, The Lions Club, The Toledo Club, Toledo, Ohio, Feb. 7, 2002.

53. Acupuncture, Mainstream Medicine?, The Academy of Medicine of Toledo and Lucas County, Winter Seminar 2002, Puerto Vallarta, Mexico, January 28, 2002. 54. Hands on Workshop: Acupuncture in Clinical Practice, The Academy of Medicine of Toledo and Lucas County, Winter Seminar 2002, Puerto Vallarta, Mexico, January 28, 2002.

CURRICULUM VITAE: RONALD S. SHAPIRO, M.D., Ph.D., F.A.C.P. 19

55. The Most Common Headache, The Academy of Medicine of Toledo and Lucas County, Winter Seminar 2002, Puerto Vallarta, Mexico, January 29, 2002. 56. Hands on Workshop: The Most common Headache, The Academy of Medicine of Toledo and Lucas County, Winter Seminar 2002, Puerto Vallarta, Mexico, January 29, 2002. 57. Renal Disease: Tips and Tools, The Academy of Medicine of Toledo and Lucas County, Winter Seminar 2002, Puerto Vallarta, Mexico, February 1, 2002. 58. Acupuncture, Mercy St. Charles

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