John Vincent George CEng MIChemE

E-mail: adehn7@r.postjobfree.com

Mobile: +1-832-***-****

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SUMMARY

A Chartered Chemical Engineer (Engineering Council, UK) with four years of research and develop- ment experience in Bioenergy/ Biochemical related projects, three years of Project Management Consultant, and ten years of combined Process Engineering and Production experience in Biochemi- cal, Oil& Gas processing projects, Fine chemicals, and pharma projects, and specialization on Process Safety Management (PSM) systems

Proven experience executing projects in research, process design & continuous improvement, scale- up, and technology transfer, process equipment validation, operating, startup & commissioning ac- tivities

Working knowledge of large-scale manufacturing facilities that comply with quality system regula- tions, GMPs

Proactive at managing projects from concept to commissioning, and leading projects with multidisci- plinary teams

SKILLS:

Molecular Biology techniques: Cell free protein synthesis, microbial culture, plasmid design & construction, DNA amplification, DNA & RNA gel electrophoresis, cell viability assays, nucleic acid extraction and purifica- tion assays, in vitro gene and DNA cloning, HPLC, filtration, sterilization, centrifugal and chromatographic separation, Crystallization, media preparation and characterization Process/ safety Engineering: Process simulation model, Process Flow Diagrams (PFD), Piping and Instrumen- tation Diagrams (P&ID), Operating, startup & commissioning manual, Design for Manufacturability, Technol- ogy Transfer, Process Control, equipment/ piping design,Anaerobic reactor, distillation, evaporation, ad- sorption, crystallization, Process Scale-Up, FMEA, HAZOP/PHA, Process validation, Quality by Design, Design of Manufacturing (DOM)

Software/Programming: MATLAB, ChemCAD, Aspen HYSYS, AutoCAD, machine learning in Python, Flarenet, LabVIEW, SAS, predictive analytics, visual programming tools Imaging and Analysis Methods: confocal microscopy, image analysis with MATLAB, Python Statistical Analysis: knowledge of Lean six sigma, Statistical Process Control (SPC), Design of Experiments

(DOE), statistical tests

PROFESSIONAL EXPERIENCE:

University of Tennessee/ ORNL, Knoxville, TN August 2017-July 2020 Graduate Research Assistant

Investigate how the physical condition of a cell such as crowding and confinement alters cell-free gene expression.

Collected data from wet-lab experiments and confocal microscope, and analyzed the big data with a statistical tool such as SAS and programming language MATLAB, Python to arrive at meaningful re- sults

Evaluate and optimize enzymatic pathway reactions for use in cell-free metabolic engineering Texas A&M, College station, TX August 2016-August 2017 Graduate Research Assistant

Implemented the production of bio-succinic acid from conceptual to lab-scale: Developed biorefin- ery model using possible feedstocks such as agricultural wastes, and conversion technology, found John Vincent George CEng MIChemE

E-mail: adehn7@r.postjobfree.com

Mobile: +1-832-***-****

Resume

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an optimal pathway, validated the modeling output with an experimental process: pretreatment, anaerobic fermentation, filtration, HPLC measurement

Applied Design Of Experiments (DOE) to find an optimal culture media and operating condition for bio-succinic acid production

Analyzed process-related impurities to support bioprocess validation in line with ICH Q6B, through mass spectrometry, spectroscopy, HPLC and chromatography assays WorleyParsons Engineering Ltd., Houston, TX September 2012-June 2015 Senior Process Engineer

Assessed the safety integrity of existing Oil &Gas processing and chemical production facilities. Activ- ities include overpressure analysis, risk ranking, adequacy check on relief valve capacity, flare and blowdown system, low-temperature study, acoustic and flow-induced vibration study and other safety integrity checks

Carried out Pre-Feed/ FEED level project for chemicals, Biodiesel, Heavy Oil Production, Oil & Water Treatment facilities, Export pipeline, Utilities

Developed HYSYS-simulation model, FLARENET-Flare network model, HYSYS-Dynamic depressuring model for chemical, Biodiesel, upstream Oil & Gas facilities

Provided critical input during HAZID/HAZOP meetings WorleyParsons Engineering Ltd., Abu Dhabi, UAE February 2009-Septemebr 2012 Project Management Consultant

Reviewed, endorsed & approved all ASSESS, FEED, EPC Contractors and vendor’s deliverables for chemical production and oil & gas processing facilities

Defined scope of work for engineering contractors

Conducted Energy efficiency/ Emission reduction study on Wellhead gathering & Dehydration, Com- pressor station, LNG plant

Assessed adequacy of existing gas processing facility by data collection and analysis of oil production and equipment details

Coordinated with Client for negotiating any scope deviations or contractual agreements with Con- sultant

Responsible for verifying man-hour estimates proposed by Contractor/ Consultant Process Engineer responsibilities:

Generated PFD’s, P&ID’s, DP/DT, MSD and datasheets for equipment and Instruments for chemical, Crude, Vacuum, and Naphtha production units & gas separation, gas treatment and compression units, hydrogen generation/ purification, export pipeline, LPG/LNG plant

Developed a Process simulation model for natural gas processing facility including gas treatment, LNG/LPG, Nitrogen compression, cryogenic operation

Performed hydraulic check & vessel sizing for process & offsite storage/ dispatch facilities

Prepared various deliverables such as process design basis, cause & effect diagram, control & safe- guarding narrative, line & equipment list, battery limit/ tie-in & hazardous source List

Actively participated in Value engineering and Optimization studies to reduce OPEX/CAPEX while en- suring safety integrity of facilities

Led the Process team during Design review, HAZOP, SIL study John Vincent George CEng MIChemE

E-mail: adehn7@r.postjobfree.com

Mobile: +1-832-***-****

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Acted as a Quality Auditor for inspecting Quality management system of Engineering consultancy companies and, as Interface engineer between different disciplines

Acted as Deputy lead to executing Conceptual to detailed engineering phase of a gas plant

Trained Junior engineers on utilizing HSYSY-Depressurizing utility and developing P&IDs L&T Chiyoda, Vadodara, India January 2005-January 2009 Process Engineer

Produced process engineering deliverables for Process & Offsite Storage/ Dispatch Facilities of crude refining units and Shell Gas-To-Liquid (GTL) projects, chemical production facilities with minimal revi- sions. The deliverables include PFD’s, P&ID’s DP/DT, MSD and datasheets for equipment and Instru- ments, Hydraulic & Vessel sizing report, operating, control, and commissioning manual, PSV sizing Orchid Pharmaceuticals, Chennai, India January 2004-December 2004 Junior Engineer-Process

To recover solvent from the waste stream used in API and drug process, I collaborated with R&D to evaluated the characteristic of waste solvents, and performed DOE in a lab-scale to find a suitable separation method and solvent, scaled up the process from lab to large scale plant. This resulted in cost savings for the project.

Associated with troubleshooting activities to improve the purity of recovered solvents using amine- based solvents in Liquid-Liquid Extraction, batch reactor, Distillation columns.

Conducted a feasibility study for recovering Iso-Propyl Alcohol (IPA) from dilute IPA by Azeotropic Distillation and validated the study results using existing equipment

Carried out FAT for new equipment and associated logic controls

Involved in Commissioning, Pre-commissioning, Stabilization activities for new Solvent recovery pro- jects

Implemented an Operational methodology Transfer in recovering Dimethyl Acetamide by Liquid-Liq- uid Extraction instead of conventional thermal method

Worked with quality engineers to develop process control plans and FMEA’s Trichy Distilleries and Chemicals, Trichy, India July 2001-January 2004 Junior Engineer-Production

Provided process design and debottlenecking solutions to day-to-day operational issues of Acetic anhydride, acetic acid, API and Ethanol plant, and new product development

Involved in optimization studies to increase the production yield of fine chemicals. Equipment han- dled: thermal cracker, distillation column, Heat exchangers, Fermenters, centrifugal separators, crys- tallizer, batch, and continuous reactor, and utilities

Performed Thermal rating of existing shell & tube heat exchanger for the expanded thermal duty of Azeo- mixture (Acetic Acid-Butyl Acetate) condenser

Produced material and energy balance report for the scaling up of fine chemicals from lab to com- mercial scale: Iso Propyl formate (IPF), Dihydro Mercinol

Performed Design of Experiment (DOE’s) and Design for Manufacturing (DFM’s) to improve product yield by finding a suitable solvent and operating condition for new API products

Utilized RCA to troubleshoot process related problems

Wrote process control sequences for batch reactions, tuned control loops John Vincent George CEng MIChemE

E-mail: adehn7@r.postjobfree.com

Mobile: +1-832-***-****

Resume

Page 4

EDUCATION:

M.S chemical and Biomolecular Engineering, University of Tennessee, Knoxville, TN, GPA =3.6/4 M.S. Energy Texas A&M College station, TX, GPA=3.9/4 B.E Chemical - Bharathiar University, Tamilnadu, India, GPA=3.6/4 REGISTRATIONS/ AFFILIATIONS

E.I.T (NCEES), working towards P.E(Texas), EIT #: 64419 CHARTERED CHEMICAL ENGINEER (CEng), IChemE Membership ID.: 99946052

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