ANSHUMAN CHANDRA

Mo. +91-701*******

adcjpq@r.postjobfree.com

Professional Qualification:

Pursuing PhD 2015-2020 on is “Designing of potential antagonist of SRPK1 for application in cancer therapy” under supervision of Dr. Imteyaz Qamar, Assistant professor, School of Biotechnology, GBU, Greater Noida, India. (Thesis submitted) S.

No

.

Course Institute/ Board Marks/

CGPA

Year of

Passing

1 Post Graduation

(Integrated B.Tech +

M.Tech in

Biotechnology

specialization in Genetic

engineering )

Gautam Buddha University 6.36 2015

2 Graduation Gautam Buddha University 6.36 2015

3 Class 12th CBSE 68% 2010

4 Class 10th CBSE 74% 2008

Experience:

Junior Research Fellow in Indian Council of Medical Research (ICMR, New Delhi) funded research project entitled “Designing of potential agonists of ASF/SF2 for application in cancer therapy”.

Six months dissertation work based on ‘Cloning, expression and purification of tRNA adenosine deaminase from Mycobacterium tuberculosis’. I have in-depth knowledge of techniques used like PAGE, Western blotting, Sequencing, Chromatography using Acta prime and crystallization setup.

Two months summer training on ‘Wound healing by Low Level Laser Therapy’ during June to August 2014 from DIPAS, DRDO, Delhi during this training, I learnt Animal handling, Basic technique used for LLLT, and Advance assays.

Two months summer training on ‘Tools & techniques used in Molecular biology’ during June to August 2013 from DIBER, DRDO, Uttarakhand. Main focus was on Genomic and plasmid DNA isolation, PCR, Gel electrophoresis and SDS-PAGE.

Training programme on ‘Marketing strategies for bio-instruments’ organized by BENCOS at New Delhi.

COMPUTATIONAL SKILL: Molecular modelling, rigid and flexible docking, virtual screening of large compound dataset, molecular dynamics simulations, protein structure determination. WET LAB SKILL: Molecular cloning, overexpression, protein purification, cell culture, immune histochemistry & Western Blotting, FACS, bacterial transformation, qRT-PCR, microscopy, RNA and DNA extraction, Molecular biology techniques, and chromatography, crystallization setups and enzyme kinetics.

Publications:

Goyal N, Chandra A, Qamar I, Singh N. Structural studies on dihydrouridine synthase A

(DusA) from Pseudomonas aeruginosa. Int J Biol Macromol. 2019 Jul 1;132:254-264. doi: 10.1016/j.ijbiomac.2019.03.209. Epub 2019 Mar 28. PMID:30928375. (IF=4.7)

Chandra A, Goyal N, Qamar I, Singh N. Identification of Hot Spot Residues on Serine- Arginine Protein Kinase-1 by Molecular Dynamics Simulation Studies. doi:10.1080/07391102.2020.1734487 (J Biomol. Struct. Dyn. In press). (IF=3.3)

Chandra A, Srivastava A, Qamar I, Singh N. Designing of Anticancer Therapeutic agents Using SRPK1 as Target. (Under Review)

Chandra A, Qamar I, Singh N. Structural insights into mechanism of specific Inhibition of SRPK1 for designing of novel anticancer compounds. (Under review)

Chandra A, Qamar I, Singh N. Mode of Specific Inhibition of SRPK1 by Human Papilloma Virus Protein E1^E4. (Under review)

Dwivedi A.K, Chandra A, Qamar I, Singh N. Characterization of TadA from Mycobacterium Tuberculosis: A Novel Target for the Action of Tetracyclines. (Manuscript under preparation)

Conference:

Abstract accepted for "28th International Conference on Cancer Research and Pharmacology (ICCRP-2020) to be held during February 21-22, 2020 at Paris, France entitled “Identification of potential antagonist of SRPK1 for application in cancer therapy”.

Presented a poster in International Conference on Emerging Advancement in Science and Technology (ICEAST 2019)"on “Identification of small molecules as inhibitors of Serine Argnine Rich Protein Kinase1".

Presented a poster in International Conference on Recent Trends in Biotechnology & Bioinformatics (ICBAB-2019) on “Identification of small molecules as inhibitors of SRPK1 for application in cancer therapy".

Presented a poster in International Conference on Recent Trends in Biotechnology & Bioinformatics (ICBAB-2019) on “Identification of small molecules as inhibitors of SRPK1 for application in cancer therapy".

Presented a poster in Insights and Innovations in Biotechnology (BIOGENESIS-V) national conference on “Designing of potential antagonist of SRPK1 for application in cancer therapy". II Prize

Awards & Achievements:

GATE – 2016, Ministry of human Resource Development (MHRD), Government of India

(GOI), New Delhi, India.

3rd prize in eco model – iTech -2012 at Gautam Buddha University, Greater Noida.

1st prize in eco model – Abhivyanjana 2011 at Gautam Buddha University, Greater Noida.

1st prize in instrumental music group competition organized by Young Men's Christian Association, New Delhi.

References:

Dr. Imteyaz Qamar, Assistant Professor, School of Biotechnology, Gautam Buddha University, Greater Noida, Uttar Pradesh- 201312 (adcjpq@r.postjobfree.com)- Supervisor

Dr. Nagendra Singh, Assistant Professor, School of Biotechnology, Gautam Buddha University, Greater Noida, Uttar Pradesh- 201312 (adcjpq@r.postjobfree.com)

Dr. Barkha Singal, Assistant Professor, School of Biotechnology, Gautam Buddha University, Greater Noida, Uttar Pradesh- 201312 (adcjpq@r.postjobfree.com) Personal Details:

Contact Address: A-88, Sector-36, Noida. (201301)

Date of Birth: 10 August 1992

Father’s Name: Suresh Chandra

I hereby Declare that the information contained above is true and to the best of my knowledge.

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