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Ph.D of Materials science & Nanotechnology

Location:
Florence, Province of Florence, Italy
Posted:
February 07, 2020

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Parisa Eslami

Ph.D of Materials Science &

Nanotechnology- Nanomedicine

Nanomedicine & Drug delivery Researcher with

More than Five Years Experience in Fabrication

and Characterization of Nanoparticles, Smart

Nanohybrids, and Polymeric Compounds for

Cancer Diagnosis and Therapy

parisa.eslami@unifi.it

+393*********

Florence, Italy

www.lamm.unifi.it/vp-226-parisa-eslami.html

linkedin.com/in/parisa-eslami-7a0a2657

TECHNICAL SKILLS

Analysis 1. TLC, Column Chromatography,

Plate Chromatography, and HPLC

Analysis 2. DLS, ICP, UV, FT-IR, NMR

Analysis 3. XRD, DSC-TG, Thermal Microscopy,

Dilatometery.

Purification 4. Crystalization and Dialysis

Technique for Polymer Purification,

Biological Test 5. Cell Viability Test, Cellular Uptake Study, and Culture Media

Preparation

SKILLS

1. Synthesis, Purification, and Characterization of pH and Thermoresponsive (Co)Polymers based PNVCL & PNIPAM Poly (N- vinylcaprolactam) and Poly (N-isopropylacrylamide) Corresponding to the RAFT Polymerization and Free Radical Polymerization Methods

2. Lab Scale Synthesis and Characterization of Nanoparticles (NPs) Including Quantum Dots and Gold Nanorods in addition to Scale-up Fabrication and Characterization of Iron Oxide Magnetic Nanoparticles (MNPs) by polyol technique for Highly Effective Magnetic Hyperthermia Cancer Therapy 3. Functionalization of Magnetic Nanoparticles by Biocompatible Polymers and Capping Ligands in addition to Doxorubicin (Drug) and Rhodamine 110 (Florecent Dye) Conjugation 4. Drug Delivery and Controlled Drug Release in Conjunction with Hyperthermia Cancer Treatment 5. Synthesis, Purification, and Characterization of Organic Compounds such as Heterocylic Compounds in addition to Thermosensitive Nanogels

6. Synthesis and Characterization of Bioglass/Biopolymer Composite as a Coating for Metallic Implant by Electrophoretic Deposition Technique

7. In Vitro Cytotoxicity Evaluation of Magnetic Nanoparticles on Melanoma Cells 8. Cellular Uptake Investigation of Magnetic Nanoparticles in Melanoma Cells Using Rhodamine 110 as Fluorescent Dye

EDUCATION

11/2015 – 04/2019

Ph.D

University of Florence

Italy, Sesto fiorentino, Florence

Nanomedicine & Drug Delivery

09/2006 – 02/2008

Master of Science

Shahid Beheshti University

Iran, Tehran

Organic Chemistry

Courses

Courses

Page 2 of 3

WORK EXPERIENCE

11/2015 – 04/2019

Ph.D Thesis

University of Florence & Colorobbia Italia s.p.a

Florence, Italy

Synthesis & Characterization of Smart Magnetic Nanocomposite (MNCs) as Multi Functional Therapeutic Agents for Drug Delivery, Controlled Drug Release & Hyperthermia Treatment Improving Synergistic Effect of combined Thermo-Chemotherapy. Synthesis & Characterization of Stimuli-Responsive (Co)Polymers Based Poly(N-Vinylcaprolactam) (PNVCL). Encapsulation of Magnetic Nanoparticles by Double pH &Thermoreponsive PNVCL to Provide Highly Stable Ferrofluid of MNCs . Exceptional Drug Loading Capacity of Obtained MNCs with Excellent Dual pH & Temperature-Triggered Controlled Drug Release under Exposure of Alternating Magnetic Field (AMF) with Low Frequency & Intensity, which is Suitable for Clinical Trials. Contact: Dr. Giovanni Baldi & Prof. Andrea Caneschi – adbnzr@r.postjobfree.com, andrea.caneschi@unifi.it 02/2015 – 10/2015

Researcher in Nanomedicine

Colorobbia Italia s.p.a

Sovigliana, vinci (FI), Italy

Development of Manufacturing Process of MNPs to Obtain NPs with Extraordinary Heat Generation Ability at Low Dosage : Scale- up Synthesis and Characterization of Flower-Like MNPs (~ 14 nm) by polyol method for Effective Hyperthermia Therapy. Contact: Dr. Giovanni Baldi – adbnzr@r.postjobfree.com 02/2013 – 02/2015

Researcher in Biomaterials Science & Engineering

Colorobbia Italia s.p.a

Sovigliana, Vinci (FI)

Fabrication and Characterization of Sol-Gel Based Bioglass-Ceramic@Chitosan as a Biocompatible Coating for Metallic Implant Using Electrophoretic Deposition (EPD) Technique

Contact: Dr. Giovanni Baldi – adbnzr@r.postjobfree.com 04/2011 – 02/2013

Researcher in Nanomedicine

Avicenna research Institute, Shahid Beheshti University Tehran, Iran

Fabrication and Characterization of Quantum Dots Nanoparticles for Cancer Imaging Scale-up Production of Biocompatible and Highly Stable QDs NPs with Narrow Size Distribution and Average Diameter of 3-4 nm for Biological Imaging

Contact: Dr. Ramin Ghahremanzadeh

09/2006 – 02/2008

Master Thesis

Shahid Beheshti University

Tehran, Iran

Synthesis and Characterization of Spiro Heterocyclic Compounds with Pharmaceutical Properties Contact: Dr. Khosrow Jadidi – adbnzr@r.postjobfree.com

RESEARCH PUBLICATION

1. Hybrid Nanogels: Stealth and Biocompatible Structures for Drug Delivery Applications, Pharmaceutics. 2019, 11, 71 P. Eslami, F. Rossi, S. Fedeli

2. A Regioselective and Diastereoselective Synthesis Spiro-Isoxazolidines via 1,3-Dipolar Cycloaddition Isatin ketonitrone and Various Dipolarophiles, Monatsh chem. 2011, 142, 917 M. Mehrdad, L. Faraji, K. Jadidi, P. Eslami, H. Sureni 3. Experimental and ab Initio Study on Structures and Internal Barriers to Rotation in α-Stannyl, Germanium and Silicon Carbamates, Journal of Molecular Structure. 2009, 920, 409 K. Jadidi, N. Ghaffari Khaligh, P. Eslami, R. aryan, H. arvinnezhad 4. Eco-Friendly Synthesis of 1,4-Benzodiazepine-2,5-Diones in Ionic Liquid [bmim]Br, Monatsh Chem. 2008, 139, 1229 K. Jadidi, R. Ghahremanzadeh, D. Asgari, P. Eslami, H. Arvinnezhad Achievements/Tasks

Achievements/Tasks

Achievements/Tasks

Achievements/Tasks

Achievements/Tasks

Page 3 of 3

HONOR AWARDS

1. Top Student Award with a Cumulative of 17.78/20 GPA (02/2005)

Shahid Beheshti University

2. Top Student Award with a Cumulative of 18.67/20 GPA with an “Excellent” Thesis Grade (02/2008)

Shahid Beheshti University

3. Marie Curie Fellowship for Research Project in

Biomaterials Science (02/2013 – 02/2015)

Ce.Ri.Col Research Center of Colorobbia Italia s.p.a Company 4. INSTM Doctorate Scholarship (10/2015 – 10/2018) University of Florence & Colorobbia Italia s.p.a

SCIENTIFIC INTERESTS

Nanotechnology, Nanomedicine, Polymer Chemistry, Organic Synthesis, Biomaterials Science, Stimuli-responsive Materials, Functional Surfaces, Drug Delivery, Nanomagnetism, Magnetic Fluid Hyperthermia, Organic-Inorganic Materials, Controlled Drug Release, Cancer Detection, Diagnosis, and Therapy, In vivo Investigation, Drug Formulation, Protein Chemistry LANGUAGES

Fluent, TOEFL (IBT) 82,

November, 2010

Professional Working

Proficiency

Persian

Native or Bilingual Proficiency

Italian

Limited Working Proficiency

CERTIFICATES & WORKSHOPS

1. HPLC Workshop, Sharif University, Tehran, Iran

(10/2011)

2. Nanotechnology Workshop (IKNW2012), Tarbiat

Modares University, Tehran, Iran (10/2012)

3. Functional Ceramics-Ferroelectrics and

Thermoelectrics Course, Politecnico di Torino, Italy

(06/2013)

4. Workshop in Glass Science and Technology,

Montpellier, France (07/2013)

5. 2th GlaCERCo Workshop, University of Erlangen,

Germany (10/2013)

6. Polymer Matrix Composite Materials workshop,

Politecnico di Torino, Italy (03/2014 – 04/2014)

7. International Sol-Gel Summer School (ISGS), Paris, France, (07/2014)

8. 3th GlaCERCo Workshop, Rennes, France

(10/2014)

9. Nanomedicine School, Bari, Italy (12/2015) 10. Workshop on Magnetism in Medicine, Florence, Italy (02/2017)

11. XIX National School of Materials Science and

Technology, Ischia, Italy (07/2017)

12. School of Nanomedicine, Bari, Italy (10/2017)

13. 4th Italian School of Magnetism, Turin, Italy

(05/2018)

CONFERENCES

1. Seminar of Organic Chemistry 9 September, 2006, Bu-Ali Sina University, Hamedan

2. Seminar of Organic Chemistry August 27-29, 2008, Razi University, Kermanshah, Iran

3. XVII International Sol-Gel Conference August,

2013, Madrid, Spain

4. 6th Forum on New Materials of “CIMTEC 2014”,

June, 2014 Montecatini Terme, Italy

5. XI National Congress on Materials Science and

Technology, July 2017, Ischia, Italy.

TRAINING COURSES

Electron Microscopy: Detection, Characterization

and Qualification of Nanomaterials (07/2018)

University of Pisa

Plasmonic and Magnetic Nanoparticles for

Biomedical Application (10/2018)

University of Florence

Peptide Based Drug Development (06/2017)

University of Florence

Nanoparticles-Based DNA Biosensors (05/2016)

University of Florence

Chemical Techniques for Attaching Peptides to

Metal Oxides and Biocompatible Polymers (05/2016)

Colorobbia Italia s.p.a

Biocompatible Polymers for Nanomedicine

Applications (06/2016)

Colorobbia Italia s.p.a



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