Parisa Eslami
Ph.D of Materials Science &
Nanotechnology- Nanomedicine
Nanomedicine & Drug delivery Researcher with
More than Five Years Experience in Fabrication
and Characterization of Nanoparticles, Smart
Nanohybrids, and Polymeric Compounds for
Cancer Diagnosis and Therapy
parisa.eslami@unifi.it
Florence, Italy
www.lamm.unifi.it/vp-226-parisa-eslami.html
linkedin.com/in/parisa-eslami-7a0a2657
TECHNICAL SKILLS
Analysis 1. TLC, Column Chromatography,
Plate Chromatography, and HPLC
Analysis 2. DLS, ICP, UV, FT-IR, NMR
Analysis 3. XRD, DSC-TG, Thermal Microscopy,
Dilatometery.
Purification 4. Crystalization and Dialysis
Technique for Polymer Purification,
Biological Test 5. Cell Viability Test, Cellular Uptake Study, and Culture Media
Preparation
SKILLS
1. Synthesis, Purification, and Characterization of pH and Thermoresponsive (Co)Polymers based PNVCL & PNIPAM Poly (N- vinylcaprolactam) and Poly (N-isopropylacrylamide) Corresponding to the RAFT Polymerization and Free Radical Polymerization Methods
2. Lab Scale Synthesis and Characterization of Nanoparticles (NPs) Including Quantum Dots and Gold Nanorods in addition to Scale-up Fabrication and Characterization of Iron Oxide Magnetic Nanoparticles (MNPs) by polyol technique for Highly Effective Magnetic Hyperthermia Cancer Therapy 3. Functionalization of Magnetic Nanoparticles by Biocompatible Polymers and Capping Ligands in addition to Doxorubicin (Drug) and Rhodamine 110 (Florecent Dye) Conjugation 4. Drug Delivery and Controlled Drug Release in Conjunction with Hyperthermia Cancer Treatment 5. Synthesis, Purification, and Characterization of Organic Compounds such as Heterocylic Compounds in addition to Thermosensitive Nanogels
6. Synthesis and Characterization of Bioglass/Biopolymer Composite as a Coating for Metallic Implant by Electrophoretic Deposition Technique
7. In Vitro Cytotoxicity Evaluation of Magnetic Nanoparticles on Melanoma Cells 8. Cellular Uptake Investigation of Magnetic Nanoparticles in Melanoma Cells Using Rhodamine 110 as Fluorescent Dye
EDUCATION
11/2015 – 04/2019
Ph.D
University of Florence
Italy, Sesto fiorentino, Florence
Nanomedicine & Drug Delivery
09/2006 – 02/2008
Master of Science
Shahid Beheshti University
Iran, Tehran
Organic Chemistry
Courses
Courses
Page 2 of 3
WORK EXPERIENCE
11/2015 – 04/2019
Ph.D Thesis
University of Florence & Colorobbia Italia s.p.a
Florence, Italy
Synthesis & Characterization of Smart Magnetic Nanocomposite (MNCs) as Multi Functional Therapeutic Agents for Drug Delivery, Controlled Drug Release & Hyperthermia Treatment Improving Synergistic Effect of combined Thermo-Chemotherapy. Synthesis & Characterization of Stimuli-Responsive (Co)Polymers Based Poly(N-Vinylcaprolactam) (PNVCL). Encapsulation of Magnetic Nanoparticles by Double pH &Thermoreponsive PNVCL to Provide Highly Stable Ferrofluid of MNCs . Exceptional Drug Loading Capacity of Obtained MNCs with Excellent Dual pH & Temperature-Triggered Controlled Drug Release under Exposure of Alternating Magnetic Field (AMF) with Low Frequency & Intensity, which is Suitable for Clinical Trials. Contact: Dr. Giovanni Baldi & Prof. Andrea Caneschi – adbnzr@r.postjobfree.com, andrea.caneschi@unifi.it 02/2015 – 10/2015
Researcher in Nanomedicine
Colorobbia Italia s.p.a
Sovigliana, vinci (FI), Italy
Development of Manufacturing Process of MNPs to Obtain NPs with Extraordinary Heat Generation Ability at Low Dosage : Scale- up Synthesis and Characterization of Flower-Like MNPs (~ 14 nm) by polyol method for Effective Hyperthermia Therapy. Contact: Dr. Giovanni Baldi – adbnzr@r.postjobfree.com 02/2013 – 02/2015
Researcher in Biomaterials Science & Engineering
Colorobbia Italia s.p.a
Sovigliana, Vinci (FI)
Fabrication and Characterization of Sol-Gel Based Bioglass-Ceramic@Chitosan as a Biocompatible Coating for Metallic Implant Using Electrophoretic Deposition (EPD) Technique
Contact: Dr. Giovanni Baldi – adbnzr@r.postjobfree.com 04/2011 – 02/2013
Researcher in Nanomedicine
Avicenna research Institute, Shahid Beheshti University Tehran, Iran
Fabrication and Characterization of Quantum Dots Nanoparticles for Cancer Imaging Scale-up Production of Biocompatible and Highly Stable QDs NPs with Narrow Size Distribution and Average Diameter of 3-4 nm for Biological Imaging
Contact: Dr. Ramin Ghahremanzadeh
09/2006 – 02/2008
Master Thesis
Shahid Beheshti University
Tehran, Iran
Synthesis and Characterization of Spiro Heterocyclic Compounds with Pharmaceutical Properties Contact: Dr. Khosrow Jadidi – adbnzr@r.postjobfree.com
RESEARCH PUBLICATION
1. Hybrid Nanogels: Stealth and Biocompatible Structures for Drug Delivery Applications, Pharmaceutics. 2019, 11, 71 P. Eslami, F. Rossi, S. Fedeli
2. A Regioselective and Diastereoselective Synthesis Spiro-Isoxazolidines via 1,3-Dipolar Cycloaddition Isatin ketonitrone and Various Dipolarophiles, Monatsh chem. 2011, 142, 917 M. Mehrdad, L. Faraji, K. Jadidi, P. Eslami, H. Sureni 3. Experimental and ab Initio Study on Structures and Internal Barriers to Rotation in α-Stannyl, Germanium and Silicon Carbamates, Journal of Molecular Structure. 2009, 920, 409 K. Jadidi, N. Ghaffari Khaligh, P. Eslami, R. aryan, H. arvinnezhad 4. Eco-Friendly Synthesis of 1,4-Benzodiazepine-2,5-Diones in Ionic Liquid [bmim]Br, Monatsh Chem. 2008, 139, 1229 K. Jadidi, R. Ghahremanzadeh, D. Asgari, P. Eslami, H. Arvinnezhad Achievements/Tasks
Achievements/Tasks
Achievements/Tasks
Achievements/Tasks
Achievements/Tasks
Page 3 of 3
HONOR AWARDS
1. Top Student Award with a Cumulative of 17.78/20 GPA (02/2005)
Shahid Beheshti University
2. Top Student Award with a Cumulative of 18.67/20 GPA with an “Excellent” Thesis Grade (02/2008)
Shahid Beheshti University
3. Marie Curie Fellowship for Research Project in
Biomaterials Science (02/2013 – 02/2015)
Ce.Ri.Col Research Center of Colorobbia Italia s.p.a Company 4. INSTM Doctorate Scholarship (10/2015 – 10/2018) University of Florence & Colorobbia Italia s.p.a
SCIENTIFIC INTERESTS
Nanotechnology, Nanomedicine, Polymer Chemistry, Organic Synthesis, Biomaterials Science, Stimuli-responsive Materials, Functional Surfaces, Drug Delivery, Nanomagnetism, Magnetic Fluid Hyperthermia, Organic-Inorganic Materials, Controlled Drug Release, Cancer Detection, Diagnosis, and Therapy, In vivo Investigation, Drug Formulation, Protein Chemistry LANGUAGES
Fluent, TOEFL (IBT) 82,
November, 2010
Professional Working
Proficiency
Persian
Native or Bilingual Proficiency
Italian
Limited Working Proficiency
CERTIFICATES & WORKSHOPS
1. HPLC Workshop, Sharif University, Tehran, Iran
(10/2011)
2. Nanotechnology Workshop (IKNW2012), Tarbiat
Modares University, Tehran, Iran (10/2012)
3. Functional Ceramics-Ferroelectrics and
Thermoelectrics Course, Politecnico di Torino, Italy
(06/2013)
4. Workshop in Glass Science and Technology,
Montpellier, France (07/2013)
5. 2th GlaCERCo Workshop, University of Erlangen,
Germany (10/2013)
6. Polymer Matrix Composite Materials workshop,
Politecnico di Torino, Italy (03/2014 – 04/2014)
7. International Sol-Gel Summer School (ISGS), Paris, France, (07/2014)
8. 3th GlaCERCo Workshop, Rennes, France
(10/2014)
9. Nanomedicine School, Bari, Italy (12/2015) 10. Workshop on Magnetism in Medicine, Florence, Italy (02/2017)
11. XIX National School of Materials Science and
Technology, Ischia, Italy (07/2017)
12. School of Nanomedicine, Bari, Italy (10/2017)
13. 4th Italian School of Magnetism, Turin, Italy
(05/2018)
CONFERENCES
1. Seminar of Organic Chemistry 9 September, 2006, Bu-Ali Sina University, Hamedan
2. Seminar of Organic Chemistry August 27-29, 2008, Razi University, Kermanshah, Iran
3. XVII International Sol-Gel Conference August,
2013, Madrid, Spain
4. 6th Forum on New Materials of “CIMTEC 2014”,
June, 2014 Montecatini Terme, Italy
5. XI National Congress on Materials Science and
Technology, July 2017, Ischia, Italy.
TRAINING COURSES
Electron Microscopy: Detection, Characterization
and Qualification of Nanomaterials (07/2018)
University of Pisa
Plasmonic and Magnetic Nanoparticles for
Biomedical Application (10/2018)
University of Florence
Peptide Based Drug Development (06/2017)
University of Florence
Nanoparticles-Based DNA Biosensors (05/2016)
University of Florence
Chemical Techniques for Attaching Peptides to
Metal Oxides and Biocompatible Polymers (05/2016)
Colorobbia Italia s.p.a
Biocompatible Polymers for Nanomedicine
Applications (06/2016)
Colorobbia Italia s.p.a