Paul E. Alexander, Bachelors (Hon), MHSc, MSC, PhD
**** *** * ****, **** 64615
Communication preference: e-mail at firstname.lastname@example.org
Re: Cover letter in support of the accompanying resume for the advertised position
Dear Human Resource Department/hiring manager,
This cover letter is an adjunct to the included resume below, tendered in the hopes of success in competing for the advertised position within your company/agency/organization.
Broadly and as an introduction, I have gained specific training and expertise in health research methods (all aspects of research methods, research design, conduct, analysis, and reporting), and particularly strong quantitative as well as qualitative and mixed methods research skills. Specific skills surround design and conduct of randomized controlled trials, meta-analyses, systematic reviews, network meta-analyses, public health and clinical practice guidelines. More importantly, prior academics and work experience has allowed the development of strong project management and executive abilities which have served me well with my past and current employer (s).
As shown in the resume and with more detail, I have completed post-secondary education including Masters education in Health Sciences at York University, Ontario; a Masters degree from the University of Toronto, Ontario, in Epidemiology; a Masters degree from the University of Oxford, Great Britain, in Evidence based medicine/clinical epidemiology; and a doctorate from McMaster University, Hamilton, in Health Research Methods/evidence based medicine/healthcare/clinical epidemiology (February/March 2015). This included a post doctorate at McMaster University. Research at McMaster, Hamilton, Ontario, University of Oxford, Great Britain, and University of Toronto, has allowed the privilege of working with the top biostatistics and research methodologists globally. Skill sets gained ranges from general and advanced epidemiology and public health, to a specialization in evidence-based medicine and statistics. Moreover, work experience spans both the local Canadian market and international market.
With this introduction, the reality is that your organization provides the chance for an enriching and rewarding career. Of importance is the chance to lead and to further develop within the workplace and the fact is that not all employment opportunities provide for this. After careful thought, I believe strongly that your organization provides a chance to contribute (executive and/or technical), as well as an opportunity to grow and develop/improve further. This is a critical deciding factor. I can function at any position within the organization, being able to both manage and provide the technical input needed. I bring to you a strong desire for life-long learning, honesty, commitment, and the framework of capacity with some very strong technical and executive/project management skills. Once fully oriented, I will quickly learn all about your organization for effective performance and success.
Let me close by asking for your consideration of this resume and at least a chance to have a face-to-face meeting whereby you can appreciate what is being offered to your organization. Allow the opportunity to share additional depth about what is being offered, and for me to learn more about your organization.
I ask you consideration.
Dr. Paul Alexander, PhD
February 1st, 2019
Dr. Paul E. Alexander
Primary e-mail: email@example.com (private)
Skills and Experience
Research methodologist (improving research methods)
Expert in evidence-based medicine (EBM) (practice and teaching)
Extensive experience conducting systematic literature reviews, meta-analyses, network-meta-
Extensive experience in synthesizing primary and meta-analytical research literature as evidence
for facilitating research, clinical medicine, and policy decisions
Extensive biostatistics, statistics skills
Member of GRADE Working Group; expert in GRADE methods application
Skills in conduct GRADE-based reviews of critical public-health questions
Extensive experience setting up disease/risk factor surveillance systems
Strong Qualitative research methods; mixed-methods
Strong Project Management skills
Advanced statistical analysis skills (use of statistical software) e.g. multivariable regression
modelling, logistic regression etc.
Extensive knowledge of clinical study design e.g. Randomized Controlled Trials (RCTs)
Computer skills Presentation skills, for example, epidemiology presentations, power-point etc.
Deep knowledge of real-world data
Advanced experience in data analytics
Expertise leading methodology and biostatistical teams
Leading with preparation of reports, presentations and papers for peer-review manuscripts/reports
20 years of hands-on medical scientific/technical writing, peer-reviewed publications
20 years of editing/writing analytical reports
20 years of scientific research
15+ years of training and development of public health/research experts
40+ peer-reviewed publications
Scientific book chapters
General Epidemiology (infectious and chronic disease epidemiology)
Public health surveillance and disease modelling
Technical skills in the epidemiology of Biological warfare, bio-terrorism, weaponization of infectious
pathogen, medical and public health/social aspects of bio-war response
Teaching (university students and clinical/surgeon medical experts EBM/research methods)
McMaster University, Hamilton, Ontario, September 2014 to present.
Department of Clinical Epidemiology and Biostatistics (CE&B), Health Research Methods.
Role of Assistant Professor (Sept 2014 to present)
Lecturer/tutor for introduction to epidemiology (MPH program, master’s level)
Lecturer/tutor for introduction to randomized controlled trial design and analysis
Lecturer/tutor for introduction to scientific research methods
Hosting seminars to surgeons, clinicians, and medical students on conducting critical appraisal of the scientific evidence
Membership in the GRADE Working Group for developing GRADE methods and the application of GRADE methods in rating the quality or certainty in evidence (study estimates of effect).
The Infectious Diseases Society of America (IDSA). Wilson Boulevard Suite 300 Arlington, Virginia (VA).
January 2017 to present.
Role of Senior Methodologist, Program Specialist, in guideline development department
Role of Evidence Based Medicine specialist in guideline development department
Role of Systematic Review and meta-analysis/network-meta-analysis conduct and management
Guideline development (all phases, conception to final guidance reports)
Providing the technical analytical input as well as the full analysis and reporting/guidance/ science-based and/or regulatory advice and recommendations to senior leadership and management
Designing and delivering guideline development and associated technical analysis classes, along with systematic and meta-analysis review training to infectious diseases specialists/guideline panel members of the USA as part of guideline development
Consultancy (research methodology) for the organizations such as American Thoracic Society (ATS)/Chest Physicians, New York, NY, January 2018 to present.
Role of consultant/methodology trainer to the American Thrombotic Society (ATS) research methodology trainee program participants involved in respective guidelines
Lead research methodologist for the American Thrombotic Society (ATS) COPD guidelines (2018/2019).
GUIDE Research Methodology Group, Hamilton, Ontario, Canada, January 2018 to present.
Role of research methodology consultant across all aspects of systematic review and meta-analysis/network meta-analysis conduct, and guideline development (http://guidecanada.org/)
Public Health Agency of Canada (PHAC), Ottawa, Ontario, January 2009 to May 2014.
Epidemiologist/researcher/evidence-based medicine in Transfusion Transmitted Injuries Surveillance System and Transfusion Errors Surveillance System (TESS) division.
Developed and lead two national surveillance systems (blood errors and injuries and tissue and organ transplant adverse events)
All lead functions (chair) and epidemiology towards monitoring federal blood transfusion related events and the transfusion error surveillance
The lead for PHAC on all unit projects (working groups) and daily statistical analysis, report writing regarding all epidemiological reporting and public health related reports, presentations, dedicated work as part of working groups on blood safety, partnering with the provinces and blood surveillance users at all levels of government and hospital settings
Duties included surveillance system design, database design, working with large surveillance datasets.
McMaster University, Hamilton, Ontario 2013-2015
Tutor, Health Research Methods. Master’s level course ‘Research Methods’.
World Health Organization (WHO) Europe Office, Copenhagen, Denmark, mid Jan 2008 to Dec 2008, post
Regional Surveillance/Epidemiology Officer Europe, internationally recruited (one-year assignment/secondment)
Epidemiology and regional surveillance technical officer and coordinator for all 52 European countries in terms of NCDs and risk factors surveillance; regional surveillance focal point for Europe, tobacco
All related research and analyses of disease risk factors and data regionally for WHO Europe country offices (direct coordination and collaboration daily with WHO Europe country office heads)
Regional surveillance officer for the four (4) nations of Poland, Russian Federation, Ukraine, and Turkey in terms of surveillance, research, epidemiology, training, project management at regional level
Pan American Health Organization (PAHO)/American Region (AMRO) and World Health Organization (WHO) Caribbean posting (OECS Caribbean states), Trinidad/Caribbean
Epidemiology and public health surveillance consultant (Dec 2007) on HIV and AIDS patient monitoring and tracking systems, surveillance, HIV drug resistance early warning indicators (EWIs)
Assessing patient monitoring and tracking systems relating HIV drug resistance, ART treatment
Addressing gaps for strengthening patient monitoring in 4 OECS Caribbean nations
Health Canada, Health Products and Food Branch Inspectorate, Ontario Region, Toronto Office
Drug Inspector (July 2005 –Oct 2007)
As a designated drug inspector, involved in the planning and conducting of investigations and compliance issues around the Food and Drugs Act and Regulations (FDA) and the Natural Health Products Regulations
All matters pertaining regulatory and compliance aspects of drugs manufactured within Canada as well as imported into Canada, for example, safety, quality, efficacy, and effectiveness.
Health Canada, Healthy Environments and Consumer Safety Branch, Ontario Region, Toronto Office
Toxicologist and Risk Assessment Specialist (July 2005 –Oct 2007)
The Ontario regional toxicologist and federal link/representative between the province and city and federal governments regarding federally owned or managed lands, buildings, properties etc. that are contaminated or potentially contaminated with toxic materials, for example, PCBs, asbestos etc.
Health Canada, Human Resources Directorate, Ontario Region, Scarborough Office
Special Advisor/Projects to the Regional Director (July 2005 –Oct 2007)
Human resources planning and needs analysis, composing and delivering employee surveys and opinion feedback; composing and conducting analysis and scans of human resources issues and practices; regional retirement analysis/forecasting, benchmarking, best practices studies, environment scans, etc.
Health Canada, Centre for Infectious Disease Prevention and Control (CIDPC),
Brooke Claxton Building, Tunney’s Pasture, Ottawa (August 2002-April 2004)
Canadian Public Health Epidemiologist
Epidemiology for CIDPC/PPHB (now PHAC)
Posted to South Asia as the in-field Canadian Public Health epidemiologist for the SAARC-Canada TB and HIV/AIDS Regional Prevention and Control Project (TB/HIV co-infection was added to the project’s mandate after my joining). The project focused on prevention and control of HIV/AIDS, TB, and TB/HIV for region countries India, Pakistan, Nepal, Bangladesh, Sri Lanka, Bhutan, Maldives.
Project management in-field, as well as providing all technical epidemiology and related inputs to drive CIDA funded SAARC-Canada 4-year Regional project. The aim was to derive suitable deliverables and outcomes
Duties entailed developing a close working relationship with UNAIDS and WHO (as well as UNICEF, UNDP, UNFPA, World Bank etc.) public health officials for South Asian (SAARC) region countries India, Pakistan, Nepal, Bangladesh, Sri Lanka, Bhutan, Maldives.
Forging partnerships regionally, setting up disease surveillance systems, networks, collaborations, meetings, seminars, discussions, policy meetings, MOUs and all aspects of collaborations.
Central West Health Information Planning Network, Hamilton, Ontario - Jan 2nd 2002 - August 2002
Population health consultant/epidemiologist
Epidemiological advice and statistical research and analysis of population health data/projects such as the potential role of SES type factors in disease (i.e. cardiovascular-type disease) with multivariate regression modeling
Spatial patterning of Palliative care utilization (revealing possible causal factors) via the use of spatial mapping and spatial analytical skills
Patterns (possible determinants) of service utilization of Home-care, Hospitalizations, Day-surgery services and all areas within the hospital setting.
Cancer Care Ontario, Preventive Oncology Department, PMH, Toronto, Ontario- May 1st 2000-Dec.31st.2000
Practicum from May to August 2000. Entailed research projects on cancer such as colon cancer, stomach cancer, and prostate cancer
Infectious disease and possible roles in chronic disease i.e. Helicobacter pylori infection and its role in gastric carcinoma
Life-analysis projects etc. Subsequent employment on contract at CCO from Sept.2nd to Dec.31st 2000.
Scarborough General Hospital/Endoscopy Unit, Scarborough, Ontario - May 1st 2000-June 2001
Epidemiologist/research #3030 Lawrence Ave. East, Suite 214, M1P2T7, Tel: 416-***-****
Researcher, as part of University of Toronto’s graduate epidemiology practicum, leading a project on colorectal cancer and surgical procedures, published in the Canadian Journal of Gastroenterology (July 2001).
TD Waterhouse, Toronto, Ontario - 1998
Stock Brokerage position, sales/customer support, completed licensing exams (CSC & CPH exams) Yonge /York Mills.
York University, Toronto, Ontario 1997
Teaching assistant/research assistant in the Faculty of Health Sciences
Duties included setting up and conducting laboratories in university courses, marking assignments and exams and managing all undergraduate student concerns.
Scotia Bank, Scarborough, Ontario - 1992-1994
Customer sales of Bank’s products, accounts, Sheppard/Midland Branch, Agincourt, Toronto
-Post-doctoral fellowship, McMaster University, Hamilton, Ontario (April 2015 to May 2016)
Under supervision of Dr. Gordon Guyatt (founder of evidence-based medicine/EBM and GRADE) working within the field of evidence-based medicine, GRADE, guideline development, and research methods.
-McMaster University, Hamilton, Ontario (March 2015 thesis defense)
Doctorate completed, PhD, Health Research Methods and Clinical Epidemiology and Biostatistics (2012-2015)
The research focused on all aspects of research methods, evidence synthesis, guideline development, use of GRADE
methods, systematic reviews, randomized controlled trial, meta-analyses design, conduct, network meta-analysis conduct and others.
-University of Oxford, Oxfordshire, England (2008 to 2011)
Masters of Science degree (MSc) Graduate student/research degree in Evidence-based medicine (EBM)/clinical epidemiology completed.
Evidence-based medicine, research methods/design, advanced statistical analysis techniques, design and conduct of randomized controlled trials, design and conduct and interpretation of systematic reviews and meta-analysis, decision analysis, advanced research design and methods
-London School of Hygiene and Tropical Medicine LSHTM (2008)
Epidemiology Fundamentals (e) course-Continuing Professional Development
A focus on measures and statistical approaches/terminology in epidemiological research.
Current epidemiology issues in public health, interventional studies, observational studies, and essentially all areas of clinical research.
-Ryerson University, Toronto, Canada (Summer 2002)
Certificate Program courses in Applied Geographic Information Systems (GIS) and Digital
-Johns Hopkins University School of Public Health and Hygiene (Bloomberg) (Summer 2001)
Graduate Institute of Epidemiology and Biostatistics at Johns Hopkins, Civilian Institute
for Bio-defense Studies, Baltimore, Maryland, U.S.A. Program
Medical and Public Health Aspects of Biological Warfare/Bioterrorism & Emergency Preparedness & Management for Global Cities.
This program involved all aspects of pathogen weaponization, delivery of weaponized pathogen such as anthrax, small-pox, plague etc. into small and large cities, all aspects of public health responses, use of all chemical, biological, radiological/nuclear etc. materials to build weapons for covert and overt use. The program aimed to focus on the public health response to an attack, all epidemiological and societal constraint/control strategies at
mitigating the outcome/risk. Warfare/ Bioterrorism& Emergency Preparedness & Management for Global Cities.
-University of Toronto (1999-2001): Faculty of Medicine, Graduate Department of Public Health
Sciences, Mc Murrich Building, 12 Queen’s Park Crescent West, Toronto, Ontario
Masters of Health Science (MHSc) completed. Epidemiology/biostatistics and Public Health degree completed.
Specialization in epidemiology (infectious diseases/chronic diseases) and public health, community health, biostatistics.
-York University (1996-1997): Dept. of Health Sciences
4700 Keele St., Downsview, Ontario
Masters of Arts (MA) Health Sciences/Health Psychology level studies, graduate courses completed included advanced statistical analyses techniques and research design methods, study design etc. Transferred to Graduate studies, University of Toronto
-York University (1992-1996): Bachelors (Specialized Honors)
4700 Keele St., Downsview, Ontario
Completed degree and undergraduate courses in statistics, intermediate and advanced statistics, chemistry,
anatomy, physiology, biology, psychology, biological psychology, natural sciences, and neurosciences.
Academic achievements and Awards:
-2014- McMaster University Doctoral Research Scholarship (part of overall funding)
-2013: McMaster University Doctoral Research Scholarship
-2012: McMaster University Doctoral Research Scholarship/Fellowship
-1996: awarded The Governor General’s Academic Medal for Honors University Results, awarded to the
graduating University student with the highest academic GPA standing
-1996: delivered Valedictorian address at York University’s spring Convocation
-2000: Graduate Epidemiology & Biostatistics award at University of Toronto
-1997-1998: Government Graduate Scholarship (OGS) for graduate research at York University
-2001-2002: Joint University of Toronto & Ryerson University Full Master’s Graduate Scholarship
-1997: awarded York’s Master’s Academic Graduate Studies Scholarship
-2000: Ontario Province OGS Government Scholarship for graduate studies at University of Toronto
-1999: awarded University of Toronto Open Fellowship
-1994: Atkinson College Retirees’ Association Award, York University
-1994: awarded the Leonard Foundation Scholarship
-1995: awarded the Leonard Foundation Scholarship/Award
-1994: awarded the York University Undergraduate Academic Scholarship
-1996: awarded the Atkinson College Students Association Academic Scholarship/York University
GRADE Working Group (http://www.gradeworkinggroup.org/), 2013-present
CLARITY statistical working group, McMaster University, Hamilton, Ontario
Network meta-analysis working group GRADE methods, 2016-present.
GUIDE Canada Research methods group (http://guidecanada.org/)
Publishing record (primary or supporting):
1. Paul E Alexander, Michael R. Gionfriddo, Shelly-Anne Li, Lisa Bero, Rebecca J Stoltzfus, Ignacio Neumann, Juan P. Brito, Benjamin Djulbegovic, Victor M. Montori, Susan L. Norris, Holger J Schünemann, Lehana Thabane, Gordon H Guyatt. A number of factors explain why WHO guideline developers make strong recommendations inconsistent with GRADE guidance. J Clin Epidemiol. 2016 Feb;70:111-22. doi: 10.1016/j.jclinepi.2015.09.006. Epub 2015 Sep 21.
2. Brignardello-Petersen R, Bonner A, Alexander PE, Siemieniuk RA, Furukawa TA, Rochwerg B, Hazlewood GS, Alhazzani W, Mustafa RA, Murad MH, Puhan MA, Schünemann HJ, Guyatt GH; GRADE Working Group. Advances in the GRADE approach to rate the certainty in estimates from a network meta-analysis. J Clin Epidemiol. 2018 Jan;93:36-44. doi: 10.1016/j.jclinepi.2017.10.005. Epub 2017 Oct 17.
3. Chatree Chai-Adisaksopha, Paul E. Alexander, Gordon Guyatt, Mark A. Crowther, Nancy M. Heddle, Martin Ellis, David Roxby, Daniel I. Sessler, John W. Eikelboom. Mortality outcomes in patients transfused with fresher versus older red blood cells: A meta-analysis. Vox Sang. 2017;112 (3):268-278. doi: 10.1111/vox.12495. Epub 2017 Feb 20.
4. Agoritsas T, Merglen A, Heen AF, Kristiansen A, Neumann I, Brito JP, Brignardello-Petersen R, Alexander PE, Rind DM, Vandvik PO, Guyatt GH. UpToDate adherence to GRADE criteria for strong recommendations: an analytical survey. BMJ Open. 2017 Nov 16;7(11):e018593. doi: 10.1136/bmjopen-201*-******.
5. Li SA, Alexander PE, Reljic T, Cuker A, Nieuwlaat R, Wiercioch W, Guyatt G, Schünemann HJ, Djulbegovic B. Evidence to Decision (EtD) framework provides a structured 'roadmap' for making GRADE guidelines recommendations.
J Clin Epidemiol. 2018 Sep 22. pii: S0895-4356(17)31403-8. doi: 10.1016/j.jclinepi.2018.09.007.
6. Alexander PE, Li SA, Gionfriddo MR, Bero L, Stoltzfus RJ, Neumann I, Brito JP, Djulbegovic B, Montori VM, Schünemann HJ, Guyatt GH. Experiences of senior GRADE methodologists as part of WHO guideline development panels: an inductive content analysis. J Clin Epidemiol. 2015 Sep 15. pii: S0895-4356(15)00422-9.
7. Timothy M. Uyeki, Henry H. Bernstein, John S. Bradley, Janet A. Englund, Thomas M. File Jr, Alicia M. Fry, Stefan Gravenstein, Frederick G. Hayden, Scott A. Harper, Jon Mark Hirshon, Michael G. Ison, B. Lynn Johnston, Shandra L. Knight, Allison McGeer, Laura E. Riley, Cameron R. Wolfe, Paul E. Alexander, and Andrew T. Pavia. Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA): 2018 Update Diagnosis, Treatment, Chemoprophylaxis and Institutional Outbreak Management of Seasonal Influenza. Clinical Infectious Diseases (CID). IDSA Influenza Clinical Guidelines 2018. November 2018, In Press. Electronic publication pages 1-47.
8. Shawwa K, Kallas R, Koujanian S, Agarwal A, Neumann I, Alexander P, Tikkinen KA, Guyatt G, Akl EA. Requirements of clinical journals for authors' disclosure of financial and non-financial conflicts of interest: a cross sectional study. PLOS ONE. 2016;11(3):e0152301. doi: 10.1371/journal.pone.0152301. eCollection 2016.
9. Zhang Y, Tikkinen KA, Agoritsas T, Ayeni OR, Alexander P, Imam M, Yoo D, Tsalatsanis A, Djulbegovic B, Thabane L, Schünemann H, Guyatt GH. Patients' values and preferences of the expected efficacy of hip arthroscopy for osteoarthritis: a protocol for a multinational structured interview-based study combined with a randomised survey on the optimal amount of information to elicit preferences. BMJ Open. 2014;4(10):e005536.
10. Alexander PE, Li SA, Tonelli M, Guyatt G. Canadian Primary Care Physicians' Attitudes Toward Understanding Clinical Practice Guidelines for Diabetes Screening. Can J Diabetes. 2016;40(6):580-585. doi: 10.1016/j.jcjd.2016.05.018. Epub 2016 Aug 30.
11. Velandia Oscar M M, Alexander PE et al. Patients values and preferences regarding continuous subcutaneous insulin infusion (CSII) and artificial pancreas in adults with type 1 diabetes: a systematic review of quantitative and qualitative data. Diabetes Technology and Therapeutics. 2019 Mar 6. doi: 10.1089/dia.2018.0346. [Epub ahead of print].
12. Alexander P, Heels-Ansdell D, Siemieniuk R, Bhatnagar N, Chang Y, Fei Y, Zhang Y, McLeod S, Prasad K, Guyatt G. Hemicraniectomy versus medical treatment with large MCA infarct: a review and meta-analysis. BMJ Open. 2016;6(11):e014390. doi: 10.1136/bmjopen-201*-******.
13. Bonner A, Alexander PE, Brignardello-Petersen R, Furukawa TA, Siemieniuk RA, Zhang Y, Wiercioch W, Florez ID, Fei Y, Agarwal A, Yepes-Nuñez JJ, Beyene J, Schünemann H, Guyatt GH. Applying GRADE to a network meta-analysis of antidepressants led to more conservativeconclusions. J Clin Epidemiol. 2018 May 22. pii: S0895-4356(17)31085-5. doi: 10.1016/j.jclinepi.2018.05.009. [Epub ahead of print].
14. Zhang Y, Flórez ID, Colunga Lozano LE, Bakar Aloweni FA, Kennedy SA, Li A, Craigie S, Zhang S, Agarwal A, Lopes LC, Devji T, Wiercioch W, Riva JJ, Wang M, Jin X, Fei Y, Alexander P, Morgano GP, Zhang Y, Carrasco-Labra A, Kahale LA, Akl EA, Schünemann HJ, Thabane L, Guyatt G. Reporting and methods for handling missing participant data for continuous outcomes in randomized controlled trials: a systematic survey. J Clin Epidemiol. 2017 Jun 2. pii: S0895-4356(17)30573-5. doi: 10.1016/j.jclinepi.2017.05.017. [Epub ahead of print].
15. Kahale LA, Diab B, Brignardello-Petersen R, Agarwal A, Mustafa RA, Kwong J, Neumann I, Li L, Lopes LC, Briel M, Busse JW, Iorio A, Vandvik PO, Alexander PE, Guyatt G, Akl EA. Systematic reviews do not adequately report, or address missing outcome data in their analyses: a methodological survey. J Clin Epidemiol. 2018 Mar 2. pii: S0895-4356(17)31397-5. doi: 10.1016/j.jclinepi.2018.02.016.
16. Siemieniuk RA, Foroutan F, Mirza R, Mah Ming J, Alexander PE, Agarwal A, Lesi O, Merglen A, Chang Y, Zhang Y, Mir H, Hepworth E, Lee Y, Zeraatkar D, Guyatt GH. Antiretroviral therapy for pregnant women living with HIV or hepatitis B: a systematic review and meta-analysis. BMJ Open. 2017 Sep 11;7(9):e019022. doi: 10.1136/bmjopen-201*-******.
17. Paul E Alexander, Rebecca Barty, Yutong Fei, Per Olav Vandvik, Menaka Pai, Reed A.C. Siemieniuk, Nancy M Heddle, Neil Blumberg, Shelley L. McLeod, Jianping Liu, John W. Eikelboom, Gordon H Guyatt. Transfusion of fresher versus older red blood cells in hospitalized patients: a systematic review and meta-analysis. Blood. 2016 ;127(4):400-10. doi: 10.1182/blood-201*-**-******. Epub 2015 Dec 1.
18. Alexander PE, Bero L, Montori VM, Brito JP, Stoltzfus R, Djulbegovic B, Neumann I, Rave S, Guyatt G. World Health Organization recommendations are often strong based on low confidence in effect estimates. J Clin Epidemiol. 2014;67(6):629-634. doi: 10.1016/j.jclinepi.2013.09.020. Epub 2014 Jan 3.
19. Siemieniuk RA, Meade MO, Alonso-Coello P, Briel M, Evaniew N, Prasad M, Alexander PE, Fei Y, Vandvik PO, Loeb M, Guyatt GH. Corticosteroid Therapy for Patients Hospitalized With Community-Acquired Pneumonia: A Systematic Review and Meta-analysis. Ann Intern Med. 2015;163(7):519-28. doi: 10.7326/M15-0715.
20. Bonner A, Alexander P et al. Application of the GRADE approach added value to the interpretation of the results of a network meta-analysis of antidepressants. J Clin Epidemiol. In Press, 2018.
21. Neumann I, Santesso N, Akl EA, Rind DM, Vandvik PO, Alonso-Coello P, Agoritsas T, Mustafa R, Alexander PE, Schunemann H, Guyatt GH. A guide for health professionals to interpret and use recommendations in guidelines developed with the GRADE approach.
J Clin Epidemiol. 2016; 72:45-55. doi: 10.1016/j.jclinepi.2015.11.017. Epub 2016 Jan 6. Review.
22. Violette PD, Agoritsas T, Alexander P, Riikonen J, Santti H, Agarwal A, Bhatnagar N, Dahm P, Montori V, Guyatt GH, Tikkinen KA. Decision aids for localized prostate cancer treatment choice: Systematic review and meta-analysis. CA Cancer J Clin. 2015;65(3):239-51. doi: 10.3322/caac.21272. Epub 2015 Mar 12.
23. Alba AC, Alexander PE, Chang J, MacIsaac J, DeFry S, Guyatt GH. High statistical heterogeneity is more frequent in meta-analysis of continuous than binary outcomes. J Clin Epidemiol. 2015. pii: S0895-4356(15)00424-2.
24. Siemieniuk RAC, Taylor GP, Guyatt GH, Lytvyn L, Chang Y, Alexander PE, Lee Y, Agoritsas T, Merglen A, Kirpalani H, Bewley S. Authors respond to "Comment from PROMISE team" Re: Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline 10 October 2017 http://www.bmj.com/content/358/bmj.j3961/rr-0.
25. Paul E Alexander, Ashley J. Bonner, Arnav Agarwal, Shelly-Anne Li, Abishek Hariharan, Zain Izhar, Neera Bhatnagar, Carolina Alba, Elie Akl, Yutong Fei, Gordon H Guyatt, Joseph Beyene. Sensitivity sub-group analysis based on single center versus multi-center trial status when interpreting meta-analyses pooled estimates: the logical way forward. J Clin Epidemiol. 2015 Nov 17. pii: S0895-4356(15)00510-7. doi: 10.1016/j.jclinepi.2015.08.027. [Epub ahead of print].
26. Akl EA, Kahale LA, Agarwal A, Al-Matari N, Ebrahim S, Alexander PE, Briel M, Petersen RB, Busse J, Diab B, Iorio A, Kwong J, Li L, Lopes LC, Mustafa R, Neumann I, Tikkinen KA, Vandvik PO, Zhang Y, Alonso-Coello