Curriculum Vitae

Name:

Kamran Salayev

Office Address:

Boston Children's Hospital

Division of Developmental Medicine

* ********* *****

Brookline, MA, 02445

E-Mail:

ad3wrq@r.postjobfree.com

Phone:

857-***-****

Education and Postdoctoral training:

09/20–02/24

Fellow

Research Bioethics

International Bioethics Research Postdoctoral Training—C. Asia Network (Harvard Medical School; Boston Children’s Hospital)

06/13–07/13

Fellow

Research Methodology and Bioethics

Summer Institute on Research Methodology and Bioethics in Health Science (Koc University in collaboration with Boston Children’s Hospital and Harvard Medical School)

04/03–03/07

Ph.D.

Neurology

School of Medicine, Tohoku University (Japan)

10/06–03/07

Ph.D.

Neonatal EEG

Dept. of Neonatology, Sendai Red Cross Hospital (Japan)

09/01–07/02

Internship

Psychiatry

Baku-city Psychiatric Hospital 2

09/95–0701

M.D.

Medicine

Azerbaijan Medical University

Academic Appointments:

10/07–08/22

Assistant professor

Dept. of Neurology and Clinical Genetics, Azerbaijan Medical University

04/03–03/07

Teaching assistant

School of Medicine, Tohoku University, Japan

Professional Positions:

2009–present

Director, Medina Medical Center for Children with Developmental Disabilities

Founded and led a multidisciplinary team of more than 50 medical and rehabilitation specialists.

Supervised all clinical services. Consulted patients with neurological disorders.

2020-2023

Neurologist, Ortopediatri Clinic

Developed neurophysiology laboratory, trained staff for neurophysiology studies. Consulted neurological patients

2021

Expert, Governmental Qualification Commission of the Ministry of Healthcare of the Azerbaijan Republic

Prepared and supervising the process of writing multiple-choice questions on pediatric neurology for the state medical licensing examination

2019

Expert, State Examination Center of the Republic of Azerbaijan

Writing multiple-choice questions on neurology for the residency board examination

2008–2009

Consultant, “USG” Non-profit organization for children with disabilities

2007–2009

Neurologist, Optimed Medical Center

Developed neurophysiology laboratory, trained staff for neurophysiology studies. Consulted neurological patients

Major Administrative Leadership Positions:

2010–2013

Course organizer

“Children and Adolescents Mental Health”:

The course consisted of 4 trainings (5 days, 6 hours per day) provided by specialists of Norwegian Uni Health to local mental health specialists

2011

Course organizer

The III Caucasian Regional Summer School on Clinical Epileptology.

The International League Against Epilepsy (ILAE).

Report of Regional and International Invited Teaching and Presentations:

2023

20th International Congress of the European Society for Child and Adolescent Psychiatry (oral presentation)

2018

Non-communicable Diseases and Global Mental Health Symposium. NIH; Harvard Medical School; Fogarty IC (oral presentation)

2016

The 2nd International Conference. Early Intervention for Disability Prevention. (oral presentation)

2016

The 7th Caucasian Regional Summer School on Clinical Epileptology. The International League Against Epilepsy (ILAE) (oral presentation, faculty member)

2012

The IV Caucasian Regional Summer School on Clinical Epileptology. The International League Against Epilepsy (ILAE). (oral presentation)

2004

American Epilepsy Society’s 58th Annual Meeting. American Epilepsy Society (poster presentation)

Professional Societies:

2018–present

Azerbaijan Medical Association, Board member

2009–present

Azerbaijan Psychiatric Association, Ethic Committee member

2021–present

International Headache Society, Member

2009–2022

International League Against Epilepsy, Azerbaijan Chapter, Member

2015–2021

World Federation of Neurologists, Azerbaijan Chapter, Member

Editorial Boards:

2017

Editorial Board member, Azerbaijan Medical Association Journal

2016

Reviewer, Azerbaijan Psychiatric Journal

2018

Reviewer, Eurasian Journal of Clinical Science

2017–2023

Ad Hoc Reviewer:

– Journal of Pediatric Neurology

– Adolescent Psychiatry

– Neurological Disorders and Epilepsy Journal

– Journal of Advanced Pediatrics and Child Health

Research grants:

2021

Fogarty Fellow research project fund, The Fogarty International Center / National Institutes of Health (FIC/NIH) funded International Bioethics Research Postdoctoral Training at the Boston Children’s Hospital and Harvard Medical School (D43TW011237) (Fellow)

2019

Research project “Intellectual disabilities in preschool children” Founded by Education Institute of Azerbaijan Republic (Primary investigator)

2019

Research project “Relationship between Level of Social Functioning and Serum Vasopressin and Saliva Cortisol in Children with Autism Spectrum Disorder,” supported by the Fogarty International Center / National Institutes of Health (FIC/NIH) funded Global Mental Health/Developmental Disorders Research Training Initiative at the Boston Children’s Hospital and Harvard Medical School (Co-investigator)

2018

Research project “Speech disorders in preschool children” Founded by Education Institute of Azerbaijan Republic (Primary investigator)

2018

Research project “Hearing impairment in preschool children” Founded by Education Institute of Azerbaijan Republic (Primary investigator)

Awards:

2003–2004

Scholarship, Rotary Club of Sendai (Japan)

Original Articles:

1.V Salpietro, R Maroofian, M Zaki, K Salayev. (2024) Bi-allelic genetic variants in the translational GTPases GTPBP1 and GTPBP2 cause a distinct identical neurodevelopmental syndrome The American Journal of Human Genetics 111 (1), 200-210

2.K Salayev, U Aslanova, K Munir. (2023) Evaluating the Decisional Capacity for Informed Consent of Transition age Children to Adolescence in Human Subject Research Journal of Empirical Research on Human Research Ethics

3.EM Toepffer, N Meave Ojeda, S Bakhtiari, S Efthymiou, R Horvath, H Lochmüller, MS Zaki, M Azam, T Ben-Omran, I Karagoz, R Kaiyrzhanov, U Guliyeva, S Gulieva, K Salayev, S Hiz, SM Hiatt, E Kunstmann, M Miryounesi, F Hashemi-Gorji, GM Cooper, H Houlden, H Jungbluth, M Kruer, J Gleeson, HS Dafsari. (2023) Expanding SNX14-Associated Movement Disorders in a Genotype–Phenotype Spectrum Neuropediatrics 54, S1-S32

4.K Salayev, U Guliyeva, S Guliyeva, R Kaiyrzhanov, U Aslanova, N Guliyeva, H Houlden, K Munir. (2023) Attitudes of Parents of Children with Rare Neurological Disorders Toward Clinical Genetic Testing In Press

5.K Saida, R Maroofian, T Sengoku, T Mitani, AT Pagnamenta, D Marafi, ... K Salayev. (2023) Brain monoamine vesicular transport disease caused by homozygous SLC18A2 variants: A study in 42 affected individuals. Genetics in Medicine 25 (1), 90-102

6.K Salayev, U Aslanova, N Guliyeva, G Geraybeyli, K Munir. (2023) Assessment of Research Ethics Knowledge of Pediatricians in Azerbaijan.

7.K Salayev, C Rocca, R Kaiyrzhanov, U Guliyeva, S Guliyeva, A Mursalova, ... (2022) AP4B1-associated hereditary spastic paraplegia: Expansion of clinico-genetic phenotype and geographic range. European Journal of Medical Genetics 65 (11), 104620

8.E Calì, SJ Lin, C Rocca, Y Sahin, A Al Shamsi, S El Chehadeh, ... K Salayev. (2022) A homozygous MED11 C-terminal variant causes a lethal neurodegenerative disease. Genetics in Medicine 24 (10), 2194-2203

9.R Kaiyrzhanov, M Ganieva, K Salayev, U Guliyeva, S Gulieva, C Shashkin, ... (2022) Whole exome sequencing in 62 families with early-onset movement disorders, cerebellar ataxia and hereditary spastic paraplegia from Kazakhstan, Tajikistan, and Azerbaijan. MOVEMENT DISORDERS 37, S289-S290

10.R Kaiyrzhanov, K Salayev, M Ganieva, B Sukhudyan, N Tabatadze, ... (2022) Whole exome sequencing in 444 families with rare paediatric neurological disorders in Central Asia and Transcaucasia. EUROPEAN JOURNAL OF NEUROLOGY 29, 164-164

11.R Kaiyrzhanov, C Rocca, M Suri, S Gulieva, MS Zaki, NZ Henig, K Siquier, ... K Salayev. (2022) Biallelic loss of EMC10 leads to mild to severe intellectual disability. Annals of Clinical and Translational Neurology 9 (7), 1080-1089

12.MA Kurian, R Kaiyrzhanov, P Allahyarova, U Guliyeva, S Gulieva, ... K Salayev. (2021) Commentary: GM1 Gangliosidosis Type III Associated Parkinsonism. Movement Disorders Clinical Practice 8 (Suppl 1), S24

13.R Kaiyrzhanov, U Guliyeva, S Gulieva, K Salayev, A Mursalova, ... (2021) GM1 gangliosidosis type III associated parkinsonism. Movement Disorders Clinical Practice 8 (Suppl 1), S21

14.C Tremblay Laganière, R Kaiyrzhanov, R Maroofian, TTM Nguyen, ... K Salayev. (2021) PIGH deficiency can be associated with severe neurodevelopmental and skeletal manifestations. Clinical Genetics 99 (2), 313-317

15.S Kamran, M Sharif, G Garay. (2019) Validation of the Azeri version of the pediatric epilepsy side effects questionnaire. Child's Nervous System 35, 2379-2383

16.V Chelban, MP Wilson, J Warman Chardon, J Vandrovcova, MN Zanetti, ... K Salayev. (2019) PDXK mutations cause polyneuropathy responsive to pyridoxal 5 phosphate supplementation. Annals of Neurology 86 (2), 225-240

17.V Salpietro, CL Dixon, H Guo, OD Bello, J Vandrovcova, S Efthymiou, ... K Salayev. (2019) AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders. Nature communications 10 (1), 3094

18.K Salayev MY Məmmədova, SS Mirzəyev. (2018) Nevroloji dilema. Eurasian Journal of Clinical Science 1 (4), 86-93

19.S Mahalov, K Salayev, T Rəhimli. (2018) Farmakorezistent gicgah payinin epilepsiyasi. (2018) “Səhiyyədə müasir nailiyyətlər” mövzusunda konfrans, Bakı.

20.K Salayev, B Sanne, R Salayev. (2017) Psychiatric and Behavioural Problems in Children and Adolescents with Epilepsy. East Asian Arch Psychiatry, 106-14.

21.K Salayev, B Sanne. (2016) The strengths and difficulties questionnaire (SDQ) in autism spectrum disorders. International Journal on Disability and Human Development, DOI: 10.1515/ijdhd-2016-0025

22.K Salayev, R Salayev, İ Rüstəmov. (2016) Güclü Tərəflər və Çətinliklər Anketinin (GTÇA) Azərbaycan versiyası. Azərbaycan psixitriya jurnalı, Bakı.

23.K Salayev, I Rustamov, N Gadjiyeva, R Salayev, B Sanne. (2014) The Discriminative Ability of the Azeri Version of the Strengths and Difficulties Questionnaire in Outpatient Practice. Community Mental Health Journal, DOI: 10.1007/s10597-014-9791-y

24.Н Абасова, М Мамедова, K Салаев. (2010) К оценке прогноза и профилактики фебрильных судорог. ATU-nun 80 illik yubileyinə həsr olunmuş beynəlxalq elmi konfrans.

25.R Rzayev, Z Əliyev, N Abasova, K Salayev, K Ağayeva, G Hüseynova. (2010) Uşaqlarda epilepsiya üzrə klinik protokol. AR SN.

26.R Rzayev, N Əliyev, N Abbasova, S Bədəlova, K Salayev, Ə Zeynalov, A Əhmədov. (2009) Epilepsiyanın diaqnostika və müalicəsi üzrə klinik protokol. AR SN.

27.С Бадалова, У Бадалова, К Салаев, М Садигов, М Миралиева, М Исмайлова. (2009) Неэпилептические пароксизмальные расстройства: критерии диагностики. II Azərbaycan Nevroloqlar Konfransının toplusu, Bakı

28.K Salayev, M Orucov. Maqnitoensefaloqrafiya vasitəsiilə epileptik ocağın müəyyən edilməsi. (2008) Nevrologiya və psixiatriyanın aktual məsələləri, Bakı.

29.K Salayev, N Nakasato, M Ishitobi, H. Shamoto, A Kanno, K Iinuma. (2007) Continuity of Surface Negativity from Fissural Cortex to Gyral Cortex at Latency of MEG Spike Peak. Neurology Asia (Supplement)

30.K Salayev, N Nakasato, M Ishitobi, H Shamoto, A Kanno, K Iinuma. (2006) Spike orientation may predict epileptogenic side across cerebral sulci containing the estimated equivalent dipole. Clinical Neurophysiology, 1836–1843

31.K Salayev, N Nakasato, M Ishitobi, H Shamoto, A Kanno, K Iinuma. Orientation of equivalent current dipole may predict epileptogenic side in central and interhemispheric MEG spikes. (2006) Journal of Japan Biomagnetism and Bioelectromagnetism Society, 244–245

32.K Salayev, N Nakasato, M Ishitobi, H Shamoto, A Kanno, T Tominaga, K. Iinuma. (2006) Evaluation of interhemispheric time difference by magnetoencephalography before and after total callosotomy. Two cases report. Neurologia medico-chirurgica (Tokyo), 136–142

33.K Salayev, N Nakasato, M Ishitobi, H Shamoto, A Kanno, K Iinuma. (2004) Comparison of MEG and EEG before and after Total Callosotomy. Epilepsia (Supplement 7), 253–254

34.K Salayev, N Nakasato, M Ishitobi, H Shamoto, A. Kanno, T Tominaga, K Iinuma. (2004) Comparison of MEG and EEG before and after Total Callosotomy. Journal of Japan Biomagnetism and Bioelectromagnetism Society, 64–65

Clinical Guidelines:

2023

Clinical Guideline on Pediatric Epilepsy. The second national clinical guideline on diagnosing and management of epilepsy in children. Adopted by the Ministry of Health of Azerbaijan Republic

2013

Clinical Guideline on Dementia. The national clinical guideline on diagnosing and management of dementia. Adopted by the Ministry of Health of Azerbaijan Republic

2010

Clinical Guideline on Pediatric Epilepsy. The first national clinical guideline on diagnosing and management of epilepsy in children. Adopted by the Ministry of Health of Azerbaijan Republic

2009

Clinical Guideline on Epilepsy. The first national clinical guideline on diagnosing and management of epilepsy. Adopted by the Ministry of Health of Azerbaijan Republic

Ph.D. Thesis:

"Spike orientation may predict epileptogenic side across cerebral sulci containing the estimated equivalent dipole"

Ph.D. Thesis in Medicine at Tohoku University, Japan, March 2007.

Translation & Adaptation:

2021

Test of Residents' Ethics Knowledge for Pediatrics, TREK-P (authors: Kesselheim, McMahon, Joffe)

2021

The University of California, San Diego Brief Assessment of Capacity to Consent, UBACC (authors: Jeste, Palmer, Appelbaum, Golshan, Glorioso, Dunn, Kim, Meeks, Kraemer)

2015

Children's Sleep Habits Questionnaire (author: Owens)

2015

Eyberg Child Behavior Inventory, ECBI (author: Eyberg)

2015

The Strengths and Difficulties Questionnaire P2–4, SDQ (author: Goodman)

2015

The Pediatric Epilepsy Side Effects Questionnaire, PEQS (author: Morita)

2013

The Development and Well-Being Assessment, DAWBA (author: Goodman)

2012

The Strengths and Difficulties Questionnaire, SDQ (author: Goodman)

Languages:

English Fluent

Russian Native

Turkish Fluent

Azeri Native

Japanese Intermediate

Social media accounts

LinkedIn https://www.linkedin.com/in/kamran-salayev/

Facebook https://www.facebook.com/Dr.Kamran.Salayev

Instagram https://www.instagram.com/drkamransalayev/

Narrative Report

I am a neurologist-scientist with an extensive background in neurodevelopmental disorders and epilepsy. I consulted over 20,000 patients over the past fifteen years. I specialize in the treatment of neurological conditions, including epilepsy, cerebral palsy, developmental delay, language disorders and autism spectrum disorders. I spend my time diagnosing and treating patients with these disabling neurological conditions and working on various research projects. I intensive training (2003-2007) in conducting and analyzing neurophysiological studies (awake and sleep EEG in neonates, children and adults; MEG and evoked magnetic fields) at Kohnan Hospital, Tohoku University and Sendai Red Cross Hospital in Japan. I analyzed independently over 25,000 EEG recordings since 2007. My approach to treatment is always patient-centered and combines drug therapy and consulting on interventional treatments (such as speech therapy, applied behavior therapy, physical and occupational therapy). I strongly emphasize preventative/prophylactic measures, life-style modification, health education, non-pharmacological treatment modalities. I have been involved in training, mentoring and educating medical students, and residents at Azerbaijan Medical University.

My academic works have focused on epileptic focus localization and presurgical evaluation of treatment resistant epilepsy patients, which compromise a significant proportion of cases. I showed that combined simultaneous application of EEG and MEG in source analysis process can provide important information that cannot be obtained by each of these modalities separately (Salayev et al., 2006). Another line of my research involved children with neurodevelopmental disorders. I translated and adopted a number of tools to study prevalence of mental symptoms among children with neurodevelopmental disorders. I studied mental symptoms in children with autism spectrum disorders and epilepsy. These studies led to changes in the national mental health guidelines. Since I was enrolled in research bioethics fellowship at Harvard Medical School and Boston Children’s Hospital funded postdoctoral training in 2000, I designed and conducted several research studies on important ethical issues in pediatrics such as assessment of pediatricians’ knowledge of ethics (Salayev et al., 2022), measuring children’s capacity for informed consent (Salayev et al., 2023), study of parental attitude toward genetic testing in rare neurological disorders (Salayev et al., 2023).

I spend considerable amount of time in social activities aimed on promoting more inclusion of people with disabilities in society. I joined the Institute of Education of the Republic of Azerbaijan as an expert in children’s neurodevelopment. Under my leadership the group of authors developed four textbooks for preschoolers that were adopted by the Ministry of Education and distributed freely among children in all governmental kindergartens (more than 150,000 copies yearly). I also authored a recommendation guide for parents of first grade primary school students that was aimed to facilitate the transit from preschool stage to primary school. In order to promote the inclusion of children with special needs, I wrote a novel depicturing a difficult path of a child with autism. This book received two international awards, was translate into English and Russian, and the comics book was created based on my story.

I truly enjoy being a neurologist and an epilepsy and neurodevelopmental disorders specialist, caring for patients, and teaching students and residents. I am honored and privileged to be able to collaborate with leading scientists in my field. I strive to improve the lives of people with epilepsy and neurodevelopmental disorder by being involved in daily care and research activities.

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