Cross-functional Scientist and Manager in Biomarker Discovery
Resume:
Shanaz Ghandhi, PhD
Cross-functional Scientist and Manager in Biomarker Discovery
ad21kc@r.postjobfree.com
Self-motivated and resilient researcher raising the bar in translational investigations on biomarker detection and validation of radiation dose and dose rate effects in human and animal models, resulting in 3 independent grants totaling $500k and 2 consortia grants totaling $50m over 10 years.
Cross-functional research management skills with extensive experience in functional omics technologies, biochemistry, RNA and protein expression using high throughput technology and multi-omics, as evidenced by 38 publications with more than 1100 citations.
Ability to work independently and within a scientific and lay-person team from design to deployment of SOPs and projects for gene biomarker discovery and development from in vitro to in vivo model systems, evidenced by 10 collaborations including one with 40 institutions worldwide and the European Network of Biological and Physical dosimetry.
WORK EXPERIENCE
R&D and Project Management Expertise in Translational Biology
Gained as an Assistant Professor of Radiation Oncology, at Columbia University Medical Center, New York
Subject Matter Expert able to expand scientific understanding relevant to radiation stress response biomarker screening and discovery for medical triage using omics analyses and machine learning on gene expression data, as evidenced by 38 separate publications submitted and published in top peer-reviewed journals and peer reviewer for 30 journals.
Technical expertise, writing and editing skills for establishment of study design and in-lab use of protocols and equipment to meet study objectives, as evidenced by lab management and training of 30 laboratory members and annual progress reports and renewal documentation.
Strong stakeholder engagement and management, maintaining contracts and business relationships resulting in 25% reduction of direct costs.
Expert at critical thinking and writing with organizational skills related to project management, prioritizing problems and solutions, grant writing, experimental design, delivery of timely results, as demonstrated by 2 consortia grants totaling $ 50m over 10 years, with 10 manuscripts in preparation.
Mentorship and Laboratory Expertise in Cellular and Molecular Biology
Gained as an Associate Research Scientist, at Columbia University Medical Center, New York
Experience working with multi-disciplinary teams with a strong ability to investigate multiomic approaches on transcriptomic and proteomic response in biofluids of varied radiation and cell-based models, as evidenced by 50 presentations including recently at the Nuclear Medical Defense conference 2023 and the Radiation Research Society conference 2022.
Growth-oriented innovative researcher with ability to advance understanding of biological response, comparisons of in vivo models of radiation, working with industry and government agencies, resulting in 5 topical publications.
Scientific leader and communicator on the radiation bystander effect investigating proteostasis and RNA biogenesis including alternative splicing, leading to 8 invited talks and posters at the International Radiation Research conference and cross-institutional events and 23 topical articles.
EDUCATION
PhD, Molecular, Cellular and Developmental Biology at The Graduate Center of the City University of New York
TECHNICAL SKILLS (selected)
Project leadership
Subject Matter Expert
Mentoring expert
Problem-Solving
Writing & Editing
Generative AI
Quantitative Research
Translational Biology
Data Analysis
PCR and analysis
Gene regulation
Aging research
Expression profiling
Human genetics
Microarrays
RNAseq
Multi-omics
Systems biology
Molecular genetics
Hub genes
Comparative analysis
Genomics
Proteomics
Transcriptomics
Science dissemination
RNA biomarkers
Animal research
Network Analysis
Radiation biology
Stress response
Biological mechanisms
System perturbation
Qualitative Research
Genomics
Lab notebook
Safety compliance Integrated OMICS Blood biomarkers Chemical Safety Blood Saliva research
Human research
Non-human primates
Biofluids
Assay validation
Gene signatures
Lab training
Presentation Skills
Technical Literacy
Equipment care
Troubleshooting
Lab maintenance
Collaboration Skills
Innovative Research
Project Management
People Management
Financial Acumen
Record management
Biomarker identification Animal models
Microsoft Office, Prizm, R, ML GCP, CITI training, IACUC and IRB
AFFILIATIONS, CERTIFICATIONS, PEER REVIEWER, AWARDS & HOBBIES
Nature Editorial Board member
Good Clinical Practice (GCP), Clinical Coordinator Mandatory training, HIPAA, and Human Subjects Protection training (including minors and FDA), Radiation, Biological and Chemical Safety training.
BMC genomics, Nature Scientific Reports, Radiation Research Journal etc. 150 scientific manuscripts peer reviewed
Radiation Research Society
Health Physics Society
European Network of Biological and Physical dosimetry
Member of the New York Academy of Sciences
American Physiological Society
Music and fashion follower
Google Scholar: http://tiny.cc/y2c8vz
Research Gate: http://tiny.cc/w2c8vz
Scopus: http://tiny.cc/23c8vz
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