Mohammad A. Yousuf (B.Sc., M.Sc., Ph.D.)
**** ***** ***** ***#***, Irving, Texas
************@*****.***
http://www.linkedin.com/
SUMMARY
Dedicated bio-medical research scientist with 15 years experience contributing to interesting research projects. Strong ability to analyze and interpret data and present findings in understandable ways that help other scientists interprets and applies the information to their own work. Demonstrated ability to author manuscripts and prepare successful grant and funding applications.
Effectively managed lab coordination by consistently ensuring supplies, equipment, staffing and more are available to support researchers and research projects. Delivered solid training and supervision to students and staff to ensure the highest quality standards are attained.
Research specialties and experience includes: mitochondrial protein function and transport mechanism, organelle purification, signaling transduction, immunology, primary cell line, gene silencing, virus production, viral entry, biochemistry, neuroinflammation, traumatic brain injury, slice pharmacology, in vivo drug testing, neurohistopathology, animal behavior, blast TBI, brain dissection, concussion TBI.
NOTABLE ACCOMPLISHMENTS
● Received a ‘Goto Award’ for excellent research activity from Gunma University Graduate School of Medicine by provide evidences of mitosomal proteins localization, function and transport mechanism that could be exploited as novel targets for development of drugs against amoebic dysentery.
●Reported for the first time that HAdV-D37 uses a lipid raft mediated caveolin-1 pathway for entry. This work provides the necessary foundation for the development of drugs to treat human keratoconjunctivitis.
TESTIMONIALS
“Dr. Yousuf has proven himself to be an excellent scientist advancing biomedical research in of national, public health interest”.
Michael Gilmore, Professor, Harvard Medical School
EDUCATION
Doctor of Philosophy, Discipline, Gunma University, Maebashi, Japan 2006-2010
Functional analysis of mitosome of Entamoeba histolytica
Master of Science, Microbiology, Dhaka University, Dhaka, Bangladesh 2001- 2002
Long lived B cell responses in cholera
Bachelor of Science, Microbiology, Dhaka University, Dhaka, Bangladesh 1996 – 2000
AWARDS, DISTINCTIONS AND FELLOWSHIPS
Monbukagakusho (Japanese Government Scholarship) 2005
Ministry of Education, Science, Sport and Culture
Government of Japan
Goto Award 2007
Gunma University Graduate School of Medicine,
For excellent research activity.
Dean’s Award 2007
Gunma University Graduate School of Medicine,
For excellent presentation at Molecular Parasitological Meeting.
Gunma University Travel Grant 2008
Gunma University Graduate School of Medicine.
ASV Travel Grant 2013
American Society for Virology
PROFESSIONAL EXPERIENCE
Senior research associate at University of Texas South Western Medical Center, Dallas 2014-2016
Studying the activation of aberrant Cdk5 in response to traumatic brain
injury by assessing the phosphorylation state of novel pathways in the brain.
Involvement of aberrant cyclin-dependent kinase5/p25 activity in experimental
traumatic brain injury.
Postdoctoral Fellow at Harvard Medical School, Mass. Eye and Ear Infirmary, Howe
Laboratory, Boston, MA. 2010-2014
Studied the role of lipid rafts in adenovirus entry into the human corneal
fibroblast and cell signaling events of corneal cells induced by adenovirus
infection.
Protein kinase C Signaling in Adenoviral Infection
Caveolin-1 Associated Adenovirus Entry into Human Corneal Cells.
PhD at Gunma University and National Institute of Infectious Diseases, Toyama, Japan. 2006-2010
Functional analysis of mitosome of Entamoeba histolytica. Studied the
localization, transport mechanism, and function of different mitosomal proteins.
Localization and Targeting of an Unusual Pyridine Nucleotide Transhydrogenase
in Entamoeba Histolytica.
Senior Research assistant at Center for Health and Population Research, 2004-2005
Dhaka Bangladesh.
Studied the immunological response in patients with enteric infections and
participants given the cholera vaccine using various enzyme immunoassays
such as ELISA, ELISPOT, Vibriocidal assay; also involved in isolating and
culturing PBMC.
SKILLS AND COMPETENCIES
Computer skills: GraphPad Prism; Microsoft Office; EndNote; Adobe Photoshop; Illustrator; ImageJ; Quantity One; SQL developer; Cisco packet tracer, Canva.
Operative system: Windows, Mac.
Programming Language: SQL, PL/SQL
Technical/Technology/Equipment skills:
Techniques: Cell culture, Molecular Biology, Viral purification, Organelles isolation, Biochemistry, Microscopy, Animal handling and behavior, Slice Pharmacology, Histopathology, Immunological techniques.
PUBLICATIONS
Protein kinase C Signaling in Adenoviral Infection. Biochemistry. 2016
Involvement of aberrant cyclin-dependent kinase5/p25 activity in
experimental traumatic brain injury. Journal of Neurochemistry 2016
Exposure to Mild Blast Forces Induces Neuropathological Effects,
Neurophysiological deficits and Biochemical Changes.
Journal of Neurochemistry. In Revision 2017
Recombination of the epsilon determinant and corneal tropism: Human
adenovirus species D types 15, 29, 56, and 69.Virology. 2015
Caveolin-1 Associated Adenovirus Entry into Human Corneal Cells. PLOS ONE. 2013
Predicting the Next Eye Pathogen: Analysis of a NovelAdenovirus. mBio. 2013
Molecular evolution of human adenoviruses. Scientific Reports. 2013
Heat Shock Protein 27 Mediated Signaling in Viral Infection. Biochemistry. 2012
Localization and Targeting of an Unusual Pyridine Nucleotide Transhydrogenase
in Entamoeba Histolytica. Eukaryotic Cell 2010
Mitosomes in Entamoeba histolytica contain a sulfate activation pathway.
Proc NatlAcadSci 2009
PRESENTATIONS/CONFERENCES/POSTERS
Unique characteristics of pyridine nucleotide transhydrogenase in
Entamoeba histolytica. International Symposium on Membrane Traffic Awaji, Japan. 2007
Cryptic dual targeting of Pyridine Nucleotide Transhydrogenase in
Entamoeba histolytica. Molecular Parasitology Meeting XIX,, Woods Hole. 2008
Differential mode of viral entry in corneal stromal cells by human adenovirus
type 37. American Society for Virology, 2011, Minneapolis, Minnesota. (Oral). 2011
Predicting the Next Corneal Pathogen: System Biology Analysis of a Novel Human
Adenovirus. ARVO, Port Lauderdola, Florida. 2011
Protein kinase C regulates the lipid raft component caveolin-1 in human
adenovirus type 37 infections of corneal fibroblasts. American Society for Virology,
Madison, Wisconsin. (Oral). 2012
Role of protein kinase C in human adenovirus type 37 infection of corneal cells.
American Society for Virology, Pennsylvania. (Oral). 2013
Adenoviral Pathogenesis in Epidemic Keratoconjunctivitis: Failure of Hexon
Gene Sequence to Predict Corneal Tropism. ARVO, Seattle, Washington. 2013
MyD88 adapter protein is required for adenoviral keratitis. Biennial
Cornea Conference, October18-19, 2013, Boston. 2013
LANGUAGES
English: “fluent written and spoken”.
Bengali: “fluent written and spoken”.
PROFESSIONAL AFFILIATIONS
Affiliate Member, American Society for Virology 2010-2015
PERSONAL INTERESTS
I take part in orphanage volunteer program.