Lab researcher, chemistry & biopharm

Cathryn Olsen

* **** ***, ******, ** ***** • 518-***-****

linkedin.com/in/cathryn-olsen • **********@*****.***

SUMMARY OF QUALIFICATIONS

Research Scientist with more than 20 years of experience at GE in analytical chemistry and method development in collaborations with the Bill and Melinda Gates Foundation for malaria rapid detection tests, GE Healthcare for product improvement & manufacturing process control, and Penn State for fluid dynamic and membrane fouling studies. Accomplishments include delivering the first ever method for TB antigen capture and developing a fluidics test to elucidate porous structure functional sizes.

Range of skills includes operation of all chem lab analytical equipment, design of experiment (DoE) for characterization, 6-Sigma, idea generation for process improvement, and documentation. Dedicated professional who demonstrates strong work ethic, time management, enjoyable teamwork, and commitment to quality.

WORK EXPERIENCE

GE Global Research Center, Niskayuna, NY 2004–2017 This leading science and technology company delivers biopharmaceutical manufacturing and purification products to the industry along with developing new biotech assays, perfusion and filtration solutions. The GE portfolio is widely diversified, spanning healthcare, aviation, energy and now, the industrial internet.

Lead Research Scientist, Materials, Manufacturing, Chemistry and Physics group.

Analyze, develop and optimize products for precise separation of biopharmaceuticals. Develop paper-based rapid diagnostic tests. Develop low-fouling bio-filtration products.

Chemical and physical characterization for product and process control.

Development of methods for ligand density quantification in chemically functionalized membranes and resins and for signal amplification in LFA.

Design of experiments and statistical analysis to assess products and results.

Extractable & leachable testing. Working knowledge of Class VI, biocompatibility.

Clean room management for antigen-antibody assay testing. Compliance with EHS, chemical waste disposal.

Laboratory equipment expertise: HPLC, UPLC, SEM, GPC, Instron, TOC, Zeta Potential, LC-OCND, ELISA immunoassay, AKTA Explorer and Crossflow, IR, UV-Vis, contact angle, lateral flow assay and development, limited DNA sequencer use.

Bristol Myers Squibb Laboratory, Syracuse, NY

Bristol Myers Squibb is a leading biopharmaceutical manufacturing company, evolving from their roots in penicillin fermentation production to current small batch biologics.

Chemist, β-lactam antibiotic development

Develop synthetic cephalosporins and optimize the processes to introduce a replacement for fermentation-produced antibiotics.

Synthetic Organic Chemistry, process development, launch of synthetic antibiotics.

Optimization of process. Statistical analysis for yields over time.

Documentation for FDA product launch.

Independent Business Experience 1986–2001

Owner of a hotel and conference center. Gained management, financial, HR experience.

PATENTS 15 total, most recent listed here.

2017: Title: High sensitivity TB Rapid Detection Test Device

Collaboration: Bill & Melinda Gates’ Global Good, Intellectual Ventures Lab, GE GRC

Submitting Contributor: CATHRYN OLSEN, Matt Misner, John Connelly, Berhard Weigl.

2016: Rapid Multiplexed Glycan monitoring by paper-based diagnostics in cell culture.

Submitting Contributor: CATHRYN OLSEN

2016: TB-LAM antigen capture for improved sensitivity in commercial Rapid DiagnosticTests

Submitting Contributor: CATHRYN OLSEN, Greg Grossman, Matt Misner.

Other patents on request, 2007-2016. Patents from the 1990s relate to plastics formulations.

PUBLICATIONS

2015: Analytical and Bioanalytical Chemistry 10/2015; 408(5). “Immobilizing affinity proteins to nitrocellulose: A toolbox for paper-based assay developers”. Holstein, Chevalier, Bennett, Yager, Zhou, Olsen.

2014: Biotechnology Progress. 11/2014; 31(1) “Effects of chemical sanitization using NaOH on the properties of polysulfone and polyethersulfone membranes.” Teela, Zhou, Olsen, Robinson, Zydney.

Additional external publications on request. (4).

GE Internal publications: 25. Physical and chemical tests methods and clean room protocols.

EDUCATION

Syracuse University, dual major in chemistry and biology, 1978.

Some medical school auditing at Upstate Medical Center. Neurophysiology, anatomy.

6-Sigma, Design Expert, ELISA testing, radioimmunoassay, biopharma seed train, bioprocess knowledge gleaned through GE, GE Healthcare, attendance at bioprocess conferences.

AWARDS

2014 GE Technical Excellence Award, 2013 GE Project of the Year Award, multiple awards for teamwork, personal drive, project support and technical contributions.

ENDORSEMENTS

From GE HR performance evaluations, 2016

Greg Grossmann, molecular biologist, 518-***-****

Cathryn is an invaluable colleague in the work we have contributed to the Bill & Melinda Gates Foundation / Global Good malaria and tuberculosis early diagnosis projects. Her broad experience and training give her tremendous facility for biosample processing in various engineered assemblies with an instinctive eye for considerations ranging from hazards containment to detection sensitivity. She has made diligent survey and intelligent choices of the technologies available for our purposes, and her clarity and creativity of thought allow for outstanding analysis and understanding of our data. Not only strongly directed towards specific project goals and timelines, as well as an effective communicator of our results to collaborators, Cathryn inspires rich discussion and ideation beyond our immediate focus in the Point-of-Care diagnostics field.

In short, she is a delight to work with, and a credit to the company!

Greg Grossmann 11/30/2016, 1:22 PM

David Moore, manager Membrane Separation Group 518-***-****

I am so thankful for all that you have done and that you do. You are so hardworking. Your passion is endless. You want to make a difference. And you have and you will continue to make a difference. Keep your ideas coming. Keep interacting without boundaries. Keep advocating for what is right. Keep being a tremendous advocate for safety and compliance. And lastly, keep keeping me honest.

David Moore 11/15/2016, 1:25 PM Manager Materials and Separations Lab

Andre St. Onge, manager GE Healthcare, Westborough, MA 508-***-****

Cathryn,

Thank you for going above and beyond supporting M1 initiatives for NPI Project Horizon-D. In particular, support around the fiber development activities. With your true diligence and timeless efforts it is greatly appreciated! As of May/11/2016 NPI project is now at M2.

Sincerely,

Horizon-D Project Manager Andre St. Onge

Andre St. Onge 05/12/2016, 9:25 AM

Thank you,

Cathryn Olsen

Available immediately due to GE’s global reorganization and new emphasis on IT.

**********@*****.*** 518-***-**** 5 references can be provided.

linkedin.com/in/cathryn-olsen

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