Senior consultant and assistant professor, Infectious diseases

CURRICULUM VITAE OF JOSE’ RAMON FIORE

PERSONAL INFORMATION

Born in Buenos Aires, Argentina, 01/29/1960

Citizenship: Italian

Male

Married

Address:

Josè Ramon Fiore

Via Fratelli De Filippo 23/a

70100 - Bari Italy

Tel: 39-080-*******

Mob: 39-329-*******

e-mail: ****.*****@*****.**

WORKING EXPERIENCE

January 14 2007 - to date Aggregate professor in Infectious Diseases

University of Foggia School of Medicine, Foggia,

Italy

Responsible for STD/HIV section

Clinic and research activity, lectures of Infectious

Diseases, Microbiology and Clinical Microbiology

January 14, 2004-2007 Researcher in Infectious Diseases, University of

Foggia, School of Medicine, Foggia, Italy

Clinic and research activity, lectures of Infectious

Diseases, Microbiology and Clinical Microbiology

June 15 1995 - January 13 2004 Consultant, Infectious Diseases, Policlinico

Hospital, University of Bari, Bari, Italy

EDUCATION AND TRAINING

1980-1987 Degree in Medicine, University of Bari, Bari, Italy

1987-1990 Specialization in Infectious Diseases, University of Bari, Bari,

Italy

1990-1994 Research Doctorate in Infectivological Sciences, University of

Bari, Bari, Italy

January 1992-december 1995 Guest scientist, Microbiology and Tumorbiology Center,

Karolinska Institute, Stockholm, Sweden (supervisors Eva

Maria Fenyo, Jan Albert, Francesca Chiodi)

December 2003 Dissertation PhD thesis in Infection Biology,

Microbiology and Tumorbiology Center, Karolinska Institute,

Stockholm, Sweden

December 2009 Specialization in Psychotherapy and Psychosomatic

Medicine, Riza Institute for Psychosomatic Medicine, Milano,

Italy

Mother tongue: Italian

Other languages: English (C1 level)

Spanish (C1 level)

LIST OF PUBLICATIONS

SUBMITTED PAPERS

IMPACT OF ADDING RALTEGRAVIR TO ANTIRETROVIRAL REGIMENS IN PATIENTS WITH FULL BLOOD VIRAL SUPPRESSION BUT PERSISTENT SEMINAL VIRAL SHEDDING: IMPLICATIONS FOR SEXUAL TRANSMISSION AND ASSISTED REPRODUCTIVE TECHNOLOGIES

Jose’ Ramòn Fiore, Mariantonietta Di Stefano, Fabio Zoboli, Giuseppina Faleo, Massimo Fasano, Teresa Santantonio 2015 AIDS (in press)

UNPROTECTED SEXUAL INTERCOURSES AMONG HIV-SERODISCORDANT COUPLES AS REVELEAD BY SEMINAL BIOMARKERS EVALUATION

Josè Ramòn Fiore, Mariantonietta Distefano, Fabio Zoboli, Giuseppina Faleo, Massimo Fasano, Teresa Santantonio (submitted)

PUBLISHED PAPERS

Impact of adding raltegravir to antiretroviral regimens in patients with blood viral suppression but persistent seminal viral shedding.

Fiore JR1, Zoboli F, Di Stefano M, Faleo G, Fasano M, Santantonio TA.

AIDS. 2016 Apr 24;30(7):1144-6

Cervical human papillomavirus infection and shedding of human immunodeficiency virus in cervicovaginal fluids: a cross-sectional study.

Fornabaio C, Carvalho AC, Lillo F, Fiore JR, Bergamaschi V, Bigoni S, Puzzi PR, Cristini G, Comelli M, Parisi MR, Matteelli A.

J Acquir Immune Defic Syndr. 2012 Sep 1;61(1):78-82. 2.

Sexual behaviour reported by a sample of Italian MSM before and after HIV diagnosis.

Camoni L, Dal Conte I, Regine V, Colucci A, Chiriotto M, Vullo V, Sebastiani M, Cordier L, Beretta R, Fiore JR, Tateo M, Affronti M, Cassarà G, Suligoi B.

Ann Ist Super Sanita. 2011;47(2):214-9. 3.

Changes in at-risk behavior for HIV infection among HIV-positive persons in Italy.

Camoni L, Regine V, Colucci A, Conte ID, Chiriotto M, Vullo V, Sebastiani M, Cordier L, Beretta R, Fiore JR, Tateo M, Affronti M, Cassarà G, Suligoi B.

AIDS Patient Care STDS. 2009 Oct;23(10):853-8. 4.

Occult HBV infection in hemodialysis setting is marked by presence of isolated antibodies to HBcAg and HCV.

Di Stefano M, Volpe A, Stallone G, Tartaglia L, Prato R, Martinelli D, Pastore G, Gesualdo L, Fiore JR.

J Nephrol. 2009 May-Jun;22(3):381-6. 5.

In vitro and in vivo human herpesvirus 8 infection of placenta.

Di Stefano M, Calabrò ML, Di Gangi IM, Cantatore S, Barbierato M, Bergamo E, Kfutwah AJ, Neri M, Chieco-Bianchi L, Greco P, Gesualdo L, Ayouba A, Menu E, Fiore JR.

PLoS One. 2008;3(12):e4073. 6.

Pregnancy and human herpesvirus 8 reactivation in human immunodeficiency virus type 1-infected women.

Lisco A, Barbierato M, Fiore JR, Gasperini P, Favia A, Volpe A, Chironna M, Pastore G, Chieco-Bianchi L, Calabrò ML.

J Clin Microbiol. 2006 Nov;44(11):3863-71. Epub 2006 Aug 30. 7.

A search for antibodies to HHV-8 in hemodialysis patients from South-Eastern Italy argues against HHV-8 spread in hemodialysis units.

Di Stefano M, Fiore JR, Pepe V, Cantatore S, Ingrassia F, Stallone G, Di Mauro L, Dentico P, Greco P, Gesualdo L.

J Clin Virol. 2006 Sep;37(1):75-6. Epub 2006 Jul 5. 8.

Isolated antibodies against the core antigen of hepatitis B virus in HIV-infected pregnant women. Ingrassia F, Fiore JR, Vimercati A, Tateo MG, Campanale F, Volpe A, Di Stefano MA, Greco P, Pastore G.

Minerva Ginecol. 2006 Jun;58(3):255-6. 9.

Detection of hepatitis C virus-RNA in saliva from chronically HCV-infected patients.

Pastore L, Fiore JR, Tateo M, De Benedittis M, Petruzzi M, Casalino C, Genchi C, Lo Muzio L, Angarano G, Serpico R.

Int J Immunopathol Pharmacol. 2006 Jan-Mar;19(1):217-24. 10.

Efficacy of famciclovir in the treatment of oral hairy leukoplakia. Pastore L, De Benedittis M, Petruzzi M, Fiore JR, Serpico R. Br J Dermatol. 2006 Feb;154(2):378-9. No abstract available. 11.

The efficiency of sperm washing in removing human immunodeficiency virus type 1 varies according to the seminal viral load.

Fiore JR, Lorusso F, Vacca M, Ladisa N, Greco P, De Palo R. 12.

Surgical experience with carotid stenosis in young HIV-1 positive patients under antiretroviral therapy: an emerging problem?

Regina G, Impedovo G, Angiletta D, Martiradonna F, Lillo A, Perilli F, Marotta V, Marzullo A, Epifani G, Fiore JR, Maggi P.

Eur J Vasc Endovasc Surg. 2005 Feb;29(2):167-70. 13.

Newly diagnosed HIV-1 infections in pregnancy: evidences from a cohort study in south-eastern Italy.

Favia A, Fiore JR, Pastore G. 14.

High seroprevalence of human herpesvirus 8 (HHV-8) in HIV-1-infected pregnant women of Southeastern Italy: association with injection drug use and hepatitis C virus infection.

Fiore JR, Volpe A, Tosatti MA, De Valentin L, Favia A, Chironna M, Lisco A, Vimercati A, Angarano G, Chieco-Bianchi L, Calabrò ML.

J Med Virol. 2004 Apr;72(4):656-60. 15.

In vitro productive infection of non polarised cervical and rectal biopsies by syncytium-inducing and non syncytium inducing primary HIV-1 isolates.

Di Stefano M, Favia A, Lisco A, Caputi Iambrenghi O, Fiore JR, Pastore G. New Microbiol. 2004 Jan;27(1):71-4.

16.

Correlates of HIV-1 shedding in cervicovaginal secretions and effects of antiretroviral therapies. Fiore JR, Suligoi B, Saracino A, Di Stefano M, Bugarini R, Lepera A, Favia A, Monno L, Angarano G, Pastore G.

AIDS. 2003 Oct 17;17(15):2169-76. 17.

Mutational patterns of paired blood and rectal biopsies in HIV-infected patients on HAART. Monno L, Punzi G, Scarabaggio T, Saracino A, Brindicci G, Fiore JR, Iambrenghi OC, Di Stefano M, Pastore G, Angarano G.

J Med Virol. 2003 May;70(1):1-9. 18.

HIV-1 shedding in genital tract of infected women. Fiore JR, Suligoi B, Monno L, Angarano G, Pastore G.

Lancet. 2002 Apr 27;359(9316):1525-6.19.

Intracellular and cell-free (infectious) HIV-1 in rectal mucosa.

Di Stefano M, Favia A, Monno L, Lopalco P, Caputi O, Scardigno AC, Pastore G, Fiore JR, Angarano G.

J Med Virol. 2001 Dec;65(4):637-43. 20.

Cervicovaginal HIV-1 shedding in pregnant women near delivery.

Saracino A, Di Stefano M, Vimercati A, Greco P, Fiore JR, Monno L, Angarano G, Pastore G. Antivir Ther. 2001 Mar;6(1):79-81.

"In vitro" spontaneous production of B-chemokines by endocervical and endometrial short-term bioptic cultures.

Favia A, Di Stefano M, Lepera A, Mangiacotti L, Saracino A, Fiore JR, Angarano G, Pastore G. New Microbiol. 2001 Jan;24(1):95-8.

22.

Intrafamilial transmission of human herpesvirus 8.

Calabrò ML, Gasperini P, Fiore JR, Barbierato M, Angarano G, Chieco-Bianchi L. J Natl Cancer Inst. 2001 Jan 17;93(2):154-6. 23.

Limited secretory-IgA response in cervicovaginal secretions from HIV-1 infected, but not high risk seronegative women: lack of correlation to genital viral shedding.

Fiore JR, Laddago V, Lepera A, La Grasta L, Di Stefano M, Saracino A, Lopalco P, Pastore G, Angarano G.

New Microbiol. 2000 Jan;23(1):85-92. 24.

Frequent detection of HIV-1 RNA but low rates of HIV-1 isolation in cervicovaginal secretions from infected women.

Saracino A, Di Stefano M, Fiore JR, Lepera A, Raimondi D, Angarano G, Pastore G. New Microbiol. 2000 Jan;23(1):79-83.

25.

Immunological markers in HIV-infected pregnant and non-pregnant women.

Vimercati A, Greco P, Lopalco PL, Loverro G, Fiore JR, Bettocchi S, Angarano G, Selvaggi L. Eur J Obstet Gynecol Reprod Biol. 2000 May;90(1):37-41.

26.

Nonproductive human immunodeficiency virus type 1 infection of human fetal astrocytes: independence from CD4 and major chemokine receptors.

Sabri F, Tresoldi E, Di Stefano M, Polo S, Monaco MC, Verani A, Fiore JR, Lusso P, Major E, Chiodi F, Scarlatti G.

Virology. 1999 Nov 25;264(2):370-84.

Phenotypic patterns of HIV-1 clonal populations during highly active antiretroviral therapy (HAART).

Favia A, Di Stefano M, Fiore JR, Pastore G, Angarano G. New Microbiol. 1999 Oct;22(4):301-7.

28.

HIV-1 disease progression in women: role of the viral phenotype of the HIV-positive steady partner. Fiore JR, Buccoliero G, Pezzotti P, Rezza G, Saracino A, Pastore G, Fenyo EM, Angarano G. AIDS. 1999 Sep 10;13(13):1801-2. No abstract available.

29.

Reproductive choice in individuals HIV-1 infected in south eastern Italy.

Greco P, Vimercati A, Fiore JR, Saracino A, Buccoliero G, Loverro G, Angarano G, Pastore G, Selvaggi L.

J Perinat Med. 1999;27(3):173-7. 30.

Evidence for a local synthesis of beta-chemokines within the genital tract of both HIV-1-infected and uninfected women.

Fiore JR, Di Stefano M, Lepera A, Saracino A, Monno L, Angarano G, Pastore G. J Acquir Immune Defic Syndr. 1999 Jul 1;21(3):255-7. No abstract available.

31.

Detection of multiple drug-resistance-associated pol mutations in cervicovaginal secretions from women largely treated with antiretroviral agents.

Di Stefano M, Fiore JR, Monno L, Lepera A, Pastore G, Angarano G. AIDS. 1999 May 28;13(8):992-4. No abstract available.

32.

Detection of human herpesvirus 8 in cervicovaginal secretions and seroprevalence in human immunodeficiency virus type 1-seropositive and -seronegative women.

Calabrò ML, Fiore JR, Favero A, Lepera A, Saracino A, Angarano G, Schulz TF, Chieco-Bianchi L. J Infect Dis. 1999 Jun;179(6):1534-7.

33.

Frequent cervicovaginal shedding of HIV-1 in asymptomatic, non-severely immunodeficient women.

Fiore JR, Lepera A, Di Stefano M, Saracino A, Favia A, Pastore G, Angarano G. AIDS. 1999 Apr 1;13(5):626-7. No abstract available.

34.

Seroprevalence of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 in several regions of Italy.

Calabrò ML, Sheldon J, Favero A, Simpson GR, Fiore JR, Gomes E, Angarano G, Chieco-Bianchi L, Schulz TF.

J Hum Virol. 1998 Mar-Apr;1(3):207-13. 35.

[Maternal viral and gestational risk factors in vertical transmission of HIV-1 infection]. Greco P, Vimercati A, Fiore JR, Kardashi A, Lotesoriere V, Loverro G, Milillo F, Selvaggi L. Minerva Ginecol. 1998 Nov;50(11):449-54. Italian.

36.

Neurological disorders during HIV-1 infection correlate with viral load in cerebrospinal fluid but not with virus phenotype.

Di Stefano M, Monno L, Fiore JR, Buccoliero G, Appice A, Perulli LM, Pastore G, Angarano G. AIDS. 1998 May 7;12(7):737-43.

37.

Measurement of viral sequences in cerebrospinal fluid of AIDS patients with cerebral white-matter lesions using polymerase chain reaction.

Monno L, Di Stefano M, Zimatore GB, Andreula CF, Appice A, Perulli LM, Fiore JR, Pastore G, Angarano G.

AIDS. 1998 Apr 16;12(6):581-90. 38.

The use of serum-free medium delays, but does not prevent, the cytotoxic effects of seminal plasma in lymphocyte cultures: implications for studies on HIV infection.

Fiore JR, La Grasta L, Di Stefano M, Buccoliero G, Pastore G, Angarano G. New Microbiol. 1997 Oct;20(4):339-44.

39.

Augmented serum neutralizing activity against primary human immunodeficiency virus type 1 (HIV-1) isolates in two groups of HIV-1-infected long-term nonprogressors.

Zhang YJ, Fracasso C, Fiore JR, Björndal A, Angarano G, Gringeri A, Fenyö EM. J Infect Dis. 1997 Nov;176(5):1180-7.

40.

Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype.

Björndal A, Deng H, Jansson M, Fiore JR, Colognesi C, Karlsson A, Albert J, Scarlatti G, Littman DR, Fenyö EM.

J Virol. 1997 Oct;71(10):7478-87. 41.

Biological correlates of HIV-1 heterosexual transmission.

Fiore JR, Zhang YJ, Björndal A, Di Stefano M, Angarano G, Pastore G, Fenyö EM. AIDS. 1997 Jul 15;11(9):1089-94.

42.

Leucocyte identification and analysis in human semen.

Maietta G, Fiore JR, Pellegrino V, Milillo G, Tagliaferro L, Corbelli M, Pastore G. Arch Androl. 1997 Mar-Apr;38(2):99-105.

43.

In vivo evidence of HIV-1 productive infection in cerebrospinal fluid of patients with HIV-1 encephalitis.

Di Stefano M, Monno L, Fiore JR, Angarano G. AIDS. 1997 Jan;11(1):133-5. No abstract available. 44.

Human immunodeficiency virus (HIV) type 1-specific B cell response in seronegative subjects at risk for HIV exposure.

Angarano G, Fiore JR, Di Stefano M, Monno L.

J Infect Dis. 1996 Aug;174(2):447-8. No abstract available. 45.

The role of HIV type 1 phenotype and genotype in long-term responders to zidovudine therapy. Angarano G, Monno L, Vivirito MC, Appice A, Romanelli C, Giannelli A, La Grasta L, Fracasso C, Fiore JR, Milazzo F.

AIDS Res Hum Retroviruses. 1996 Jul 20;12(11):969-75. 46.

Prevalence and incidence of HIV-1 syncytium-inducing phenotype among injecting drug users in south-eastern Italy.

Angarano G, Monno L, Fiore JR, Fracasso C, La Grasta L, Romanelli C. AIDS. 1996 Jun;10(7):805-6. No abstract available.

47.

HTLV-I and HTLV-II infections in subjects at risk for HIV-I infection from southeastern Italy (Apulia region).

Chironna M, Calabrò ML, Quarto M, Germinario C, Fiore JR, Favero A, Potenza D, Chieco-Bianchi L, Barbuti S.

Int J Cancer. 1996 Mar 15;65(6):746-50. 48.

P24 antigen detection, viral isolation, DNA-PCR and in vitro antibody production for the diagnosis of HIV-1 latent infection in heterosexual women at high risk for HIV-1 infection.

Di Stefano M, Fiore JR, Chironna M, Buccoliero G, Romanelli C, La Grasta L, Quarto M, Angarano G, Pastore G.

Genitourin Med. 1995 Apr;71(2):123-5. 49.

The biological phenotype of HIV-1 is usually retained during and after sexual transmission. Fiore JR, Björndal A, Peipke KA, Di Stefano M, Angarano G, Pastore G, Gaines H, Fenyö EM, Albert J.

Virology. 1994 Oct;204(1):297-303. 50.

Detection of human T lymphotropic virus type II/b in human immunodeficiency virus type 1-coinfected persons in southeastern Italy.

Calabró ML, Luparello M, Grottola A, Del Mistro A, Fiore JR, Angarano G, Chieco-Bianchi L. J Infect Dis. 1993 Nov;168(5):1273-7.

51.

A simple method to detect HIV-1 protein specificity of IgG intrathecal synthesis in HIV-1 infection. Carbonara S, Angarano G, Quarto M, Germinario C, Chironna M, Fiore JR, Monno L, Barbuti S, Pastore G.

New Microbiol. 1993 Apr;16(2):121-7. 52.

Preliminary data on the establishment of permanent cell lines continuously producing HIV-1: factors affecting the transmissibility and adaptability of "wild" HIV-1 isolates.

Di Stefano M, Fiore JR, Angarano G, Fico C, Grottola A, Pastore G. New Microbiol. 1993 Jan;16(1):19-26.

53.

Correlation between seroreactivity to HIV-1 V3 loop peptides and male-to-female heterosexual transmission.

Fiore JR, Jansson M, Scarlatti G, Angarano G, Caputo SL, Buccoliero G, Rossi P, Fenyö EM, Pastore G.

AIDS. 1993 Jan;7(1):29-31. 54.

HIV-1 isolation from small amounts of whole blood: a technical evaluation.

Fiore JR, Angarano G, Fico C, Di Stefano M, Grottola A, Monno L, Fracasso C, Pastore G. Microbiologica. 1992 Jan;15(1):35-44.

55.

In vitro production of HIV-1 specific antibodies from "at risk" seronegative subjects.

Quarto M, Fiore JR, Chironna M, Fontana A, Germinario C, Troiano T, Fico C, Congedo P, Grottola A, Monno L, et al.

Microbiologica. 1992 Jan;15(1):29-33. 56.

Pokeweed mitogen-stimulated peripheral blood mononuclear cells from at-risk seronegative subjects produce in vitro HIV-1-specific antibodies.

Fiore JR, Angarano G, Fico C, Quarto M, Congedo P, di Stefano M, Grottola A, Monno L, Germinario C, Fontana A, et al.

AIDS. 1991 Aug;5(8):1034-6. No abstract available. 57.

Lack of HBV and HDV replicative activity in HBsAg-positive intravenous drug addicts with immune deficiency due to HIV.

Monno L, Angarano G, Santantonio T, Milella M, Carbonara S, Fiore JR, Fico C, Pastore G. J Med Virol. 1991 Jul;34(3):199-205.

58.

[Isolation of human immunodeficiency virus (HIV) from whole blood]. Fiore JR, Angarano G, Fico C, Di Stefano M, Fracasso C, Pastore G. Boll Soc Ital Biol Sper. 1991 May;67(5):535-42. Italian.

59.

[Analysis of the replication kinetics in primary culture of isolates of HIV-1 from infected patients in various stages of the disease].

Fiore JR, Angarano G, Fico C, Di Stefano M, Monno L, Pastore G. Boll Soc Ital Biol Sper. 1991 May;67(5):529-34.

60

Different biological properties of paired HIV-1 isolates from peripheral blood mononuclear cells and cerebrospinal fluid.

Fiore JR, Angarano G, Fico C, Monno L, Zimatore GB, Di Stefano M, Fracasso C, Pastore G. Acta Neurol (Napoli). 1991 Feb;13(1):31-6.

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