Georgia Southern University
Abha Sood
Dept.of Chemistry and Biochemistry Apt # 1026
Ph: 857-***-**** Statesboro
*****@***************.*** GA-30461
Education
**** -**** ******sity of Texas Health Medical School, Houston, TX Postdoctoral Research Associate (Department of Neurology) 2007-2012 University of Massachusetts, Boston, MA
Ph.D in Chemistry (Biological Chemistry track)
2004-2006 Panjab University, Chandigarh, India
M.Sc (Honors) in Chemistry (Department of Chemistry) 2001-2004 Panjab University, Chandigarh, India
B.Sc (Honors) in Chemistry (Department of Chemistry) Employment History
2014-Current Limited term teaching faculty at Georgia Southern University 2012-2014 Postdoctoral research fellow at University of Texas health Medical School at Houston 2008-2012 Teaching Assistant (II), Umass Boston
2007-2008 Teaching Assistant (I), Umass Boston
Research and Technical/Linguistic Skills
• iClicker, Document Camera, Desire2Learn, Use of Simulations for teaching various topics, LabQuest.
• UV-Vis spectrophotometers; Fluorescence spectrometers; FTIR; NMR; Mass spectrometry.
• In-depth working knowledge of Wet chemistry. Titration methods ; Experience with instruments such as Atomic force microscopy, Gas Chromatography
• Technically proficient with MS Office (Word, Excel, Powerpoint), Adobe (Reader/Writer, Photoshop), ChemDraw, Web of science, Scifinder.
• Proficiency in English, Hindi, Punjabi. IELTS score 8.0 (June, 2016) Research Interests/Experience
Biochemistry and Organic Chemistry: Development and quantification of protein aggregation assays and characterization of aggregates using atomic force microscopy, Fluorescence microscopy, Size exclusion high performance liquid chromatography, ELISA. Design and synthesis of small organic drug like molecules and their characterization using Column Chromatography, High Performance Liquid Chromatography, LC-Mass Spectroscopy, GC-Mass Spectroscopy. Toxicity studies of small molecules in ex-vivo cell proliferation assays
Research History
Postdoctoral Research Associate UT Health Medical School, Houston (2012-2014) PI: Dr. Claudio Soto
Research Description:
• Recognized and Targeted Common Pathways of Many Neurodegenerative Diseases (Alzheimer’s and Prion Disease).
• Designed, Screened and Developed SAR Studies of Small Molecule Inhibitors of Calcineurin Enzyme: One of the Novel Target Involved in the Pathogenesis of Various Neurodegenerative Diseases.
• Performed Protein Mis-folding Amplification.(PMCA)
• Studied Adaptability of vCJD Prion Strain to Different Physiological Environment.
• Performed Early Diagnosis of Prion Protein in Blood. Graduate Research Associate University of Massachusetts Boston, MA (2007-2012) PI: Dr. Marianna Torok
Research Description:
• Targeted Multiple Pathways Involved in the Pathogenesis of Alzheimer’s Disease.
• Discovered and Published 3 main Lead Compounds, Active Against Amyloid β Protein Self- Assembly, Potent Cholinesterase Inhibitors, Excellent Anti-Oxidant Property, Thorough Systematic Structure Activity Relationship Studies. (SAR)
• Elucidated Structural Feature Requirement of Aβ Fibril and Oligomer Inhibitors Separately.
• Discovered and Published Important Structural Findings to Distinguish between Fibril vs Oligomer Inhibitors of Aβ Aggregation
Master’s and Bachelor’s Projects Panjab University, Chandigarh, India (2001-2006) PI: Dr. Paramjit Singh
Research Description:
• Promoted Stereoselective Lithiation-Substitution of Tertiary Amines and Phosphines with Lewis Acid
Teaching Experience
Faculty
2014-Current Georgia Southern University
• Teaching Nursing Chemistry class (Chem-1151), Student strength-144
• Teaching and conducting Laboratory (Chem-1151, 1145)
• Teaching Chemistry principles I (Chem-1145)
Teaching Assistant
2008-2012 University of Massachusetts, Boston
• Laboratory Instructor for undergraduate General chemistry (CH-117) and Organic Chemistry Labs (CH-255). Solely responsible for functioning of lab and course material
• Teaching Assistant for Undergraduate Biochemistry II Lab (CH-386-****-**** University of Massachusetts Boston
• Teaching Assistant for undergraduate General and Organic lab (CH-256)
• Lectured Biochemistry discussion session and conducted one on one problem solving session with students
• 5 years of directly advising and supervising 6 undergraduate and 5 graduate students towards the completion of their honors project
• Helping with Poster preparation and presentation skills for undergraduate students at various national and regional undergraduate conferences
Awards and Honors
2013 UMB Chancellor's “Distinguished Dissertation Award in the Physical Sciences” (2012-2013) 2012 Alzheimer's Drug Discovery Foundation Young Investigator Scholarship UMB Chemistry Program Award for Outstanding Achievement. 2011 UMB Office of International and Transnational Affairs' Student Travel Support. UMB Chemistry Department Vincent Mastricola Award, Awarded to Highest Performing Graduate Student.
2009-2011 UMass representative of ACS, Northeastern Section of Younger Chemists Committee. (NSYCC) 2008-2010 Member of Golden Key International Society: Invitation Only. (OSWP-GPA) 2006 Joint CSIR-University Grants Commission (UGC) National Eligibility Test (NET) for Lectureship, Government of India.
2006 Merit Certificate for standing third in Bachelor’s in entire Department. Professional Development and Service
2014-2015: Workshops Attended
• Teaching the Net Generation (Ms. Louis Fetcher and Ms. Judith Longfield (Centers for Teaching and Technology; CT2), Georgia Southern University
• Writing a Teaching Philosophy Part 1-2 (Ms. Judith Longfield)
• Folio Foundations - Quizzes Workshop
• Applying the Quality Matters Rubric (APPQMR) workshop 2014-2016: Service
• Member of open house committee. Help organizing and representing chemistry department at Majors fair at GSU.
• Organized and participated in Science Olympiad for Middle and High school students at Georgia Southern University. February, 2015.
• Judged both oral and poster presentations at 15
th
annual Research Symposium at Georgia
Southern University. April, 2016.
• Served as an active reviewer for “Turkish Journal of Chemistry” and “Biomedical and Chemistry Letters” peer reviewed Journals (invitation by the editor).
• Line-up Assistant for Undergraduate Commencement Ceremony for spring 2015 Professional Affiliations and Contribution
2007-2011 Member, American Chemical Society
2008-2011 Member of Northeastern Section of Younger Chemists Society 2011 Volunteered at Organizing Green Chemistry Symposium Held at UMass Boston Publications
Invited Review Article
Datta S, Sood, A, Torok M. Steps toward Green Peptide Synthesis. Current Organic Synthesis, 8, 262-280, 2011 Research Publications
Horton W, Sood A, Peerannawar S, Kugyela N, Kulkarni A, Tulsan R, Tran C, Soule J, LeVine H, Török B, Török M. Synthesis and Application of beta-Carbolines as Novel Multi-functional Anti-Alzheimer’s Disease Agents. Bioorganic & Medicinal Chemistry Letters, 2016 (accepted for publication)
Sood A, Brown A, Alonzo J, Sutton S, Christianson M, Stocking R, Torok B, Landge S. Effect of solvent polarity on the regioselective hydroxyalkylation of indole with trifluoroacetaldehyde hemiacetals. Tetrahedron Letters, 2016 (Submitted)
Bag S, Tulsan R, Sood A, Cho H, Redjeb H, Zhou W, Levine H, Torok B, Torok M. Sulfonamide as multifunctional agents for Alzheimers disease, Bioorganic & Medicinal Chemistry Letters, 2015, 25: 626-630
Török B, Sood A, Bag S, Tulsan R, Ghosh S, Borkin D, Kennedy A R, Melanson M, Madden R, Zhou W, LeVine H III, Török M. Diaryl Hydrazones as Multifunctional Inhibitors of Amyloid Self-Assembly Biochemistry, 2013, 52: 1137-1148
Bag S, Ghosh S, Tulsan R, Sood A, Zhou W, Schifone C, Foster M, LeVine H III, Török B, Török M. Design, Synthesis and Biological Activity of Multifunctional α,β-Unsaturated Carbonyl Scaffolds for Alzheimer’s Disease. Bioorganic & Medicinal Chemistry Letters, 2013, 23: 2614-2618
Melanson M, Sood A, Török B, Török M Introduction to Spin Label Electron Paramagnetic Resonance Spectroscopy of Proteins. Biochemistry and Molecular Biology Education, 2013, 41: 156-162
Bag S, Tulsan R, Sood A, Datta S, Török M. Pharmacophore Modeling, Virtual and In Vitro Screening for Acetylcholinesterase Inhibitors and their Effects on Amyloid-ß Self-assembly. Current Computer-Aided Drug Design, 2013, 9: 2-14
Torok B, Sood A, Bag S, Kulkarni A, Borkin D, Lawler E, Dasgupta S, Landge S, Abid M, Zhou W, Foster M, LeVine H. and Torok M. “Structure Activity Relationship of Organofluorine Inhibitors of Amyloid Beta Self- Assembly, ChemMedChem, 2012, 7, 910-919
Sood A, Abid M, Sauer C, Hailemichael S, Foster M, Török B, Török M. Disassembly of Preformed Amyloid βeta Fibrils by Small Organofluorine Molecules Bioorganic & Medicinal Chemistry Letters, 2011, 21, 2044-2047
Borkin D, Morzhina E, Datta S, Rudnitskaya A, Sood A, Török M, Török B. Heteropoly Acid-Catalyzed Microwave-Assisted Three-Component Aza-Diels-Alder Cyclizations: Diastereoselective Synthesis of Potential Drug Candidates for Alzheimer’s Disease Organic and Biomolecular Chemistry, 2011, 9, 1394-1401
Sood A, Abid M, Hailemichael S, Foster M, Török B, Török M. Effect of Chirality of Small Molecule Organofluorine Inhibitors of Amyloid Self-Assembly on Inhibitor Potency. Biorganic & Medicinal Chemistry Letters, 2009, 19, 6931-6934
References
• Dr. Marianna Torok
Associate Professor of Chemistry
University of Massachusetts Boston
Department of Chemistry
Ph: 617-***-****
Email: ********.*****@***.***
• Dr. Bela Torok
Associate Professor of Chemistry
University of Massachusetts Boston
Department of Chemistry
Ph: 617-***-****
Email: ****.*****@***.***
• Ms. Jessica Orvis
Associate Professor
Department of Chemistry
Georgia Southern University
Ph: 912-***-****
Email: *******@***************.***