CURRICULUM VITAE

Dr. Madhu LN

S/o U Narayana

Thenginahitlu

Ullal Bail, Ullal

Mangalore-575020, India

acxtff@r.postjobfree.com

Mob: +919*********

Professional Objective

To be an asset to my work place through the application of my skills in logical thinking, organizing, research, communication, and leadership.

Education Details

Courses Name of Institute University/Board Year of passing Percentage of marks PhD (Biotechnology) Nitte University Nitte University May 2014 - M.Sc(Biotechnology) Mangalore University Mangalore University 2009 69.08 B.Sc (Biochemistry,

Zoology, Botany)

St. Aloysius college Mangalore University 2007 70

P. U. C Vishwamangala P U

College, Konaje

Department of Pre

University Education

2004 57.83

S. S. L. C St. Sebastian High

School, Ullal

Karnataka Secondary

Education

Examination Board

2002 75.68

Personal Details

Name : Madhu L N Date of Birth : 23-03-1987

Father’s Name : Narayana U Sex : Male

Mother’s Name : Leelavathi K Nationality : Indian

Mobile : +919********* Religion : Hindu

Residence : 082*-******* Marital Status : Married

Email : acxtff@r.postjobfree.com Passport No. : H1349978 K-SET

Cleared Karnataka State eligibility test for lectureship/Assistant Professor PhD Thesis Title

In vivo Studies on Comparative and Synergistic Radioprotective Effect of Triazole Derivatives and Nardostachys jatamansi

Work Experience

Presently working as a Assistant professor at St. Aloysius College, Mangalore for MSc Biochemistry

4 Year Teaching experience at St. Aloysius College, Mangalore for MSc Biochemistry

2 year Research experience as Junior Research Fellow at Nitte University

4 months Research experience as Senior Research Fellow at Nitte University External Funded Projects

As Principal Investigator

UGC Minor Project-In vivo Antiangiogenesis and Tumor Suppressive Property of Thiazole Acetamide Derivatives- (2013-2015)- Amount-Rs. 2,00,000/-

BRNS Major Project- In Vitro Studies of Chemotherapeutic Drug Sensitivity On Acquired Radio- Resistance Breast Cancer Cells- (2014-2016)- Amount-Rs. 15,11,750/- Member

Life member of Indian Association of Biomedical Scientists (IABMS). Skill set

Good knowledge of Biochemical analysis, Animal handling experiments, cell culture and maintainance.

Molecular biology techniques of Genomic and Plasmid DNA isolation, Cloning Experiments. Restriction digestion, Ligation, Transformation. PAGE, Agarose gel electrophoresis, Western blotting,

Micro nucleus assay, comet assay, cell viability and proliferation assays, maintenance of experimental animals like mice, rat.

Plant and Animal tissue culture- Primary explant culture, Lymphocyte culture, cell line maintenance, Tumor transplantation, and various methods of plant tissue culture. Computer skills

Compute basics, Microsoft office, Statistical software’s -PRISM, SPSS. Communication skills

Languages known: English, Kannada, Hindi, Tulu.

Publications

1. Madhu LN. Sham Rao, BK, Sarojini. No impact on P-gp level in radioresistant MCF-7 cells

(Abstract) . Journal of Radiation and Cancer research 2016; 7(5): 2-56. 2. Vijay R, Vishakh R, Sharmila K P, Madhu L N, Pushpalatha K C, Suchetha Kumari. Effect of Sub lethal dose electron beam irradiation on Swiss albino mice lung: A pilot Study. International Journal for Agro Veterinary and Medical Sciences 2015; 9(2): 51-60. 3. Prakash S. Nayak, B. Narayana, B. K. Sarojini, Jennifer Fernades, B. R. Bharath, L. N. Madhu. Synthesis, molecular docking and biological evaluation of novel bis-pyrazole derivatives for analgesic, anti-inflammatory and antimicrobial activities. Medicinal Chemistry Research 2015; DOI 10.1007/s00044-015-1467-9. 4. Shama Rao, Sukanya Shetty, Suchetha Kumari Nalilu, Madhu LN. Radioprotective Properties of Chitosan on Cultured Human Lymphocytes against Electron Beam Radiation. Journal of Applied Pharmaceutical Science 2015; 5(08):147-151. 5. Viveka S, Madhu LN, Nagaraja GK. Synthesis of new pyrazole derivatives via multicomponent reaction and evaluation of their antimicrobial and antioxidant activities. Monatshefte für Chemie - Chemical Monthly. DOI: 10.1007/s00706-015-1428-5. 6. Shama Rao, Sukanya Shetty, Suchetha Kumari N, Madhu LN, Ganesh Sanjeev. Radioprotective properties of Allium sativum (Garlic) extract on cultured Human lymphocytes against electron beam radiation. International Journal of Pharmaceutical Sciences and Drug Research 2015;7(2): 151-156.

7. Suchetha Kumari N, Madhu L N. Dietary supplementation of Natural and synthetic products reduces anxiety in mice against electron beam radiation induced oxidative stress. Nitte University Journal of Health Sciences 2014;4(3): 28-32. 8. Madhu L N, Suchetha Kumari N, Sarojini B K. Radioprotective effect of 4-amino-4H-1,2,4- triazole-3-thiole against electron beam radiation induced Biochemical and Clastogenic effect. Journal of Pharmacy Research 2014;8(3):400-404

9. Sapna Kumari M, Narayana B, Sarojini BK, Madhu LN. Synthesis of new indazole derivatives as potential antioxidant agent. Medicinal Chemistry Research 2014; 23:2368- 2376. DOI: 10.1007/s00044-013-0835-6.

10. L N Madhu, N S Kumari. Radioprotective effect of sulphydryl group containing triazole derivative to modulate the radiation – induced clastogenic effects. Research in Pharmaceutical Sciences 2014; 9(1): 23-29.

11. Sukanya Shetty, Shama Rao, SuchethaKumari N, Madhu L N, Vishakh R. Modulatory effect of Allium sativumEthanolic Extract on Cultured Human Lymphocytes. Journal of Applied Pharmaceutical Science 2013; 3(4): 073-077. 12. L N Madhu, N Suchetha Kumari N, P Naveen, Ganesh Sanjeev. Protective effect of Nardostachys jatamansi against radiation-induced damage at biochemical and chromosomal levels in swiss albino mice. Indian Journal of Pharmaceutical Science 2012; 74(5): 460-465.

13. Shankar Shetty, Suchetha Kumari N, Madhu L N. Oxidative stress, antioxidant status and DNA damage in Type 2 diabetes melittus. Research journal of pharmaceutical, biological and chemical sciences 2013; 4(1): 437-443.

14. Madhu L N, Suchetha Kumari N, Vijay R. Validation of DNA Damage Progression with Days after Single Exposure of Sublethal Dosage of Electron Beam Radiation. Journal of Applied Pharmaceutical Science 2012; 2(12): 023-026. 15. S. Samshuddin, B. Narayana, B.K.Sarojini, L. N. Madhu. A study on the reactions of alkyl 4,6-bis(4-fluorophenyl)-2- oxocyclohex-3-ene-1-carboxylate and in vitro antioxidant activity of derivatives. Medicinal Chemistry Research 2013; 22(6): 3002-3011. 16. Shankar Shetty, Suchetha Kumari N, Madhu LN. Variation in serum Myloperoxidase levels with respect to hyperglycemia, duration of diabetes, BMI, sex and aging in type 2 diabetes mellitus. International journal of research in pharmaceutical and biomedical sciences 2012; 3(2): 652-655

17. Suchetha Kumari N, Madhu L N, Satheesh Bhandary, Sukanya Shetty, Veena Shetty. Evaluation of Erythrocyte antioxidant defense enzyme activity in electron beam irradiated mice. Proceedings of International conference on Emerging frontiers and Challenges in radiation biology, January 24-25, 2012. Page No. 169-173. 18. N. Suchetha Kumari, L.N. Madhu, Protective Effect of Nardostachys jatamansi on Radiation Induced Anxiety and Oxidative Stress. Biomedicine: 2012; 32(3): 337- 341. 19. L N Madhu, N Suchetha Kumari, Ganesh Sanjeev, Efficiency of Nardostachys jatamansi extract in modifying electron beam radiation induced mortality and clastogenicity in mice. Journal of Pharmacy Research 2011; 4(12): 451*-****-**. Madhu L N, Suchetha Kumari N, Sarojini BK. In vitro and In vivo antioxidant property of sulphydryl group containing 1, 2, 4 Triazole derivative. Drug Invention Today 2011; 3(12): 297-300.

21. Suchetha Kumari. N, Madhu L N. Effect of electron beam radiation on hematopoietic cells of Swiss Albino mice. Nitte University journal of Health science 2011; 1: 15-18. 22. Suchetha Kumari. N, K M Damodara Gowda, Sukesh N, Madhu L N, Kathyayani, “Effect of yoga therapy on body mass index and oxidative status” Nitte University journal of Health science 2011; 1: 10-14.

23. Naveen P, Suchetha Kumari N, Ganesh Sanjeev, Damodara Gowda K M, Madhu L N. Radioprotective effect of Nardostachys jatamansi against whole body electron beam induced oxidative stress and tissue injury in rats. Journal of Pharmacy Research 2011; 4(7): 2197- 2200.

24. N Suchetha Kumari, L N Madhu, Ganesh sanjeev. Effect of Electron Beam radiation on Antioxidant status of Swiss albino mice. Proceedings of NAARRI international conference, dec13-15, 2010. Page No. 413-416.

25. Siddartha, Pooja Mohan Rao, Suchetha Kumari N, Sampath Kumar, Madhu LN. An epidemiology of prevalence of Type 2 Diabetes among the adult residents in Dakshina Kannada district, Research Journal of Pharmaceutical, Biological and Chemical Sciences 2010; 1(3): 586.

26. Shenoy Manjunath, Suchetha Kumari N., Shetty Gaurav, Madhu L.N., Ramitha K. Status of Lipid Perodixation And Sialic Acid in Generelised Vitiligo. Journal of Advance Researches in Biological Sciences 2010; (Special Issue) 33-36. 27. Hongqi Li, B. K. Sarojini, C. G. D. Raj, L. N. Madhu and H. S.Yathirajan. (E)-3-(3- Bromophenyl)-1-(4-methylphenyl) prop-2-en-1-one, Acta Cryst. 2008; E64: o2238. Papers Presented at conferences

1. Madhu LN, Shama Rao, Sarojini BK. No Impact on P-gp in Radioresistant MCF-7 cell lines. International conference on Radiation research 2016, BARC, Mumbai 2. Madhu LN1, Sandeep Telkar, Divyalaxmi Kamath, Melita Evan D souza, Shama Rao, Prakash S Nayak. In vitro anticancer property VEGF inhibition by thiazole acetamide derivative. Global cancer summit 2015. IISc Bangalore. 3. Madhu LN, Divyalaxmi Kamath, Melita Evan D souza, Shama Rao, Prakash S Nayak. Synthesis of Novel Thiazole Acetamide Derivatives and Tumor suppressive property against HeLa and Erlich’s Ascites Cancer. National Conference on New vistas in Biological sciences, Jan 2015, St Aloysius College, Mangalore. 4. Shama Rao, Madhu LN, Sukanya Shetty, Suchetha Kumari N. Radiosensitizing effect of chitosan on HeLa and LN 18 brain tumor cells exposed to electron beam radiation. International Conference on Radiation Biology. November 2014. New Delhi 5. Madhu L N, Suchetha Kumari N. Radioprotective effect of sulphydryl group containing triazole derivative to modulate the radiation- induced clastogenic effects. International conference on radiation Biology. October 2013, Nitte University, Mangalore 6. Madhu L N, Suchetha Kumari N, Vijay R. Radiation- induced DNA damage in human lymphocytes and their prevention by sulphydryl group containing 1, 2, 4 triazole. National conference on Perspectives of Biotechnology in Health and Industry. 24-25 Feb 2012. Alva’s College, Moodabidri, Mangalore.

7. Vijay R, Krishna Nayak, Suchetha Kumari N, Dilip Quadros, Madhu L N, Ajay Dethose. Assessment of DNA damage in Buccal Mucosa Cells and Lymphocytes in Subjects treated with Nickel Stainless steel Orthodontic Appliances. National conference on Perspectives of Biotechnology in Health and Industry. 24-25 Feb 2012. Alva’s College, Moodabidri, Mangalore.

8. Madhu L N, Suchetha Kumari N, Vijay R. Comet Assay Based Evaluation of Single Strand DNA Breaks in Lymphocytes of Mice Exposed to Whole Body Electron Beam Radiation. International Conference- Molecular Medicine-2012. 19-22 Feb 2012. VIT University, Vellore.

9. Satheesh Bandary, Suchetha Kumari N, Madhu L N. Protective Effect of Nardostachys jatamansi on Radiation Induced Anxiety and Oxidative Stress in Mice. International conference on Emerging frontiers and challenges in radiation biology. 24-25 Jan, 2012. Bikener, Rajasthan.

10. N. Suchetha Kumari, L.N. Madhu. Radioprotective Effect of Sulphydryl Group Containing Triazole Derivative to Modulate the Radiation- Induced Clastogenic Effects. International conference on Emerging frontiers and challenges in radiation biology. 24-25 Jan, 2012. Bikener, Rajasthan.

11. Sukanya shetty, Suchetha Kumari N, Madhu L N. Effect of Electron Beam Radiation on Hematopoietic Cells of Swiss Albino Mice. International conference on Emerging frontiers and challenges in radiation biology. 24-25 Jan, 2012. Bikener, Rajasthan. 12. L N Madhu, N Suchetha Kumari, Ganesh Sanjeev. Efficiency of Nardostachys jatamansi Extract in Modifying Electron Beam Radiation Induced Mortality and Clastogenicity in Mice. IABMS conference 2011, Punjab University, Chadigarh. 13. Suchetha Kumari N, Madhu L N. Using Sulphydryl Group Containing Triazole Derivative- Novel Approach for Radioprotection. IABMS conference 2011, Punjab University, Chadigarh.

14. Mahesh Bekal, Suchetha Kumari, Madhu L N, Vijay R. Affects of Electron Beam Radiation on memory, learning ability and Anxiety levels of mice. IABMS conference 2011, Punjab University, Chadigarh.

15. Vijay R, Suchetha Kumari N, Madhu L N, Mahesh Prasad B, Sharmila K P. In vitro Evaluation of Synergistic Antioxidant Potential of Punica garnatum and Gallic Acid. IABMS conference 2011, Punjab University, Chadigarh. 16. Madhu L N, Suchetha Kumari N, Naveen P, Samshuddin S. In vitro and In vivo Antioxidant Property of 1, 2, 4 Triazole Derivatives. World Congress Biotechnology 2011, Hyderabad. 17. Madhu L N, Suchetha Kumari N, Narayana B, Ganesh Sanjeev, Sarojini B K, Naveen P, Samshuddin S, Damodara G. Protective Effect Of 1,2,4 Triazole On Electron Beam Radiation Induced Oxidative Stress In Swiss Albino Mice. International conference “ICRB 2010-chennai” Nev 15-17, 2010.

18. L N Madhu, N.Suchetha Kumari, B.Narayana, P.Naveen, Ganesh Sanjeev. Electron Beam Radiation Dosage On Antioxidant Status In Swiss Albino Mice. International conference

“APSRC 2010-Lonavala, Mumbai. Sep 14-17, 2010.

19. Shetty Gaurav, Shenoy Manjunath,Madhu.L.N, Kumari Suchetha N ‘Evaluation of serum Sialic acid and Malondialdehyde level in generalized Vitiligo disease and control groups’ International Conference on “Genetic and Molecular Diagnosis in Modern Medicine and Biology” 27feb-1march 2010 at Yenapoya University, Mangalore, India. 20. B.K.Sarojini, Mustafa Khaleel, C.G.Darshan Raj, L.N.Madhu ‘Studies on Antioxidant property of (2E)-3-(substituted aryl)-1-(2-hydroxyphenyl)-prop-2-en-1-ones’ International conference on Frontiers in Chemical research ICFCR-2008 held on Dec. 28-31, 2008 at Department of Chemistry, Mangalore University, India PP-20 21. B.K.Sarojini, B.Narayana N.Suchetha Kumari, C.G.Darshan Raj, L.N.Madhu Studies on Antioxidant property of new Chalcone and Bischalcone derivatives’ International conference on Frontiers in Chemical research ICFCR-2008 held on Dec. 28-31, 2008 at Department of Chemistry, Mangalore University,India OP-20. References

Dr. Suchetha Kumari N

Professor

Dept. of Biochemistry

K.S.Hegde Medical Academy

Nitte University

Deralakatte, Mangalore-575018

Dr. B. Narayana

Professor

Department of Chemistry

Mangalore University

Mangalagangotri

Konaje, Mangalore

B.K.Sarojini

Professor

Department of Industrial Chemistry

Mangalore University

Mangalore

Declaration

I solemnly declare that, the above statements made by me in this form are correct to the best of my knowledge and belief.

Place: Mangalore MADHU L N

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