Manning *

Kylie Brooke Manning

**** ********** ****** ***. *** Hoboken, NJ 07030 Home: 717-***-**** acxnxg@r.postjobfree.com Cell: 717-***-****

EDUCATION

New York University, New York, NY 2012-Present

Graduate School of Arts and Sciences

Molecular Design Institute

Received Ph.D. Candidacy May 2014, Chemistry, Emphasis: Synthetic Supramolecular Polymers GPA: 3.84/4.00

Degree Expected: March 2017

Susquehanna University, Selinsgrove, PA 2008-2012

ACS certified B.S., Chemistry. GPA: 3.79/4.00

Degree Earned: May 2012

RESEARCH EXPERIENCE (Principle Investigator: Dr. Marcus Weck)

• New York University, Molecular Design Institute Fall 2012-Present Synthesis of a small library of telechelic, secondary structure-like polymers containing noncovalent recognition motifs at their chain ends as building blocks towards large tertiary polymer constructs. Working to synthesize a rigid-helical, telechelic bulky poly(methacrylamide)s. This building block will be incorporated with other synthetic helical, sheet-forming or random coil polymers via noncovalent recognition motifs at their chain ends. The supramolecular assembly behavior of synthetic tertiary polymer constructs will be probed via a battery of analytical techniques.

• New York University, Molecular Design Institute and CUNY Summer 2016-Present Antifouling polymer for the patterning of functional amines using AFM thermochemical nanolithography. Designed a polymer scaffold containing thermally labile carbamates, crosslinking cinnamates, and varying ratios of anti-fouling sulfobetaine. The polymers were screened as candidates for AFM thermochemical nanolithography in order to pattern amines as functional handles for bioconjugation while preventing nonspecific protein absorption.

• Susquehanna University, (Dr. Geneive Henry) Fall 2011-Spring 2012 Isolation and purification of possible biologically active secondary metabolites from Hypericum mutilum.

Utilized silica gel chromatography, reversed-phase HPLC, and TLC to isolate secondary metabolites from various extracts of Hypericum mutilum at differing stages of purification. The compound structures were characterized on the basis of 1H, 13C and 2D NMR (HMQC, HMBC) data.

• Susquehanna University, (Dr. Geneive Henry) Fall 2010-Spring 2011 Acylphloroglucinol and xanthones from Hypericum ellipticum. An acylphloroglucinol, elliptophenone A, and two xanthones, elliptoxanthone A and elliptoxanthone B, were isolated from the aerial portions of Hypericum ellipticum together with three known xanthones. Their structures were determined by spectroscopic analyses. The acylphloroglucinol and xanthones were evaluated for cytotoxicity using three human colon cancer cell lines (HT-29, HCT- 116 and Caco-2) and a normal human colon cell line (CCD-18Co). Manning 2

• Susquehanna University Summer Research Partners Program Summer 2010 New xanthones from Hypericum ellipticum.

Utilized silica gel chromatography, reversed-phase HPLC, and TLC to isolate secondary metabolites from the plant species Hypericum ellipticum. The structures were characterized on the basis of 1H, 13C and 2D NMR (HMQC, HMBC) data. Purification of an acetone extract of the plant afforded three trihydroxy-xanthones: 8-prenylxanthone. 1,6-dihydroxy-4-methoxyxanthone, 1,4,5-trihydroxyxanthone, and 1,4,

• Susquehanna University, (Dr. Tammy Tobin) Fall 2009-Spring 2010 Bacteria that live in extreme coal mining-impacted environments. Investigated the impacts that bacteria have on ongoing remediation efforts in Shamokin Creek, a waterway severely impacted by acid mine drainage.

PUBLICATIONS

• Elacqua, E.; Croom, A.; Manning, K. B.; Pomerico, S. K.; Lye, D., Young, L.; Weck, M. Supramolecular Diblock Copolymers Featuring Well-defined Telechelic Building Blocks. Accepted to Angewandte Chemie, 2016.

• Manning, K,; Croom, A.; Weck, M. Supramolecular Helix-Helix Block Copolymers. Macromolecules. 2016, 49, 7117-7128.

• Manning, K.; Shtukenberg, A.; Nichols, S.; Kahr, B.; Weck, M. Synthesis and liquid crystalline behavior of bulky poly(methacrylamide)s. J. Polym. Sci. A Polym. Chem., 2015, 53, 2563–2568. Cover of Journal

• Manning, K.; Petrunak, E.; Lebo, M.; González-Sarrías, A.; Seeram, N. P.; Henry, G. E., Acylphloroglucinol and xanthones from Hypericum ellipticum. Phytochemistry 2011, 72 (7), 6. PRESENTATIONS

• Invited Speaker. Kylie B. Manning, Graduate Student Seminar, Synthesis of supramolecularly functionalized, helical poly(methacrylates): Towards topologically diverse block copolymers, New York University, New York, NY (June 2016)

• Marcus Weck, Elizabeth Elacqua, Anna Croom, Kylie Manning, Supramolecular Block Copolymers, Middle Atlantic Regional ACS Meeting, Riverdale, NY (June 2016)

• Marcus Weck, Anna Croom, Beth Elacqua, Kylie Manning, Foldable Supramolecular Block Copolymers, ACS National Meeting, Boston, MA (August 2015)

• Invited speaker, Kylie B. Manning, Synthesis of supramolecular, end-functionalized helical polymers: Towards well-defined secondary structures. Susquehanna University, Selinsgrove, PA

(February 2015)

• Kylie B. Manning and Dr. Geneive Henry, Chemical composition of a hexane extract of Hypericum mutilum. ACS National Meeting, San Diego, CA (March 2012)

• Kylie B. Manning and Dr. Geneive Henry, Acylphloroglucinol and xanthones from Hypericum ellipticum. ACS National Meeting, Anaheim, CA (March 2011)

• Kylie B. Manning and Dr. Geneive Henry. New xanthones from Hypericum ellipticum. Landmark Summer Research Conference, Juniata College, Huntingdon, PA (July 2010) (1st Place) GRANT PROPOSALS AND FUNDING

• Aided in the writing and editing process of a 2015 NSF grant proposal that was accepted for funding by the National Science Foundation

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SKILLS

• Experimental: Small molecule synthesis, structurally unique and functional monomers, RAFT, ROMP, ATRP controlled polymerization techniques, uncontrolled radical polymerization

• Instrumentation: Bruker AV-400 High Performance Digital NMR Spectrometer (400 MHz), Bruker AV-500 High Performance Digital NMR Spectrometer (500 MHz), Bruker AVIII-600 High Performance Digital NMR Spectrometer (600 MHz), Jeol 400 MHz NMR, Aviv Stopped Flow CD Spectropolarimeter Model 202SF, Agilent 1100 Series Capillary LCMSD Trap XCT Spectrometer, Agilent 1100 Series LCMSD VL MS Spectrometer, Shimadzu HPLC/GPC, Waters 1525 HPLC, Agilent 1200 Series HPLC/GPC, Cary 4000 UV-Vis, Lambda 950 UV-Vis, HP 8452A UV-Vis, Nicolet Magna -560-ESP FT-IR, Fluorescence spectrometer, Thermo Nicolet AVATAR FTIR Spectrometer, YAG laser, Atomic Absorption Spectrometer, bomb calorimetry, Ion Chromatograph, GC/MS, Size Exclusion Chromatography

• Computational: Chemdraw, Gaussian03, Mathematica, Visual Molecular Dynamics, MS Office, MatLab, MestReNova.

TEACHING EXPERIENCE

New York University

Teaching Assistant: Organic Chemistry I Lab (2 Sections) September-December 2014 Teaching Assistant: Organic Chemistry II Lab January-May 2014 Teaching Assistant: Principles of Organic Chemistry Lab January-May 2014 Teaching Assistant: Organic Chemistry I Recitations (2 Sections) September-December 2014 Teaching Assistant: Organic Chemistry II Recitation January-May 2013 Teaching Assistant: Introduction to Modern Chemistry Lab January-May 2013 Teaching Assistant: Organic Chemistry II Lab January-May 2013 Teaching Assistant: General Chemistry Lab (2 Sections) Summer 2013 Teaching Assistant: Organic Chemistry I Lab September-December 2013 Susquehanna University

Teaching Assistant: Organic Chemistry I and II Fall 2010-2012 Aided in general laboratory instruction and use of advanced instrumentation. Tutor: General Chemistry and Organic Chemistry 2009-2012 Held weekly tutoring sessions for students in General Chemistry and Organic Chemistry. VOLENTEER WORK- NEW YORK UNIVERSITY

Show inner-city elementary school students (4th and 5th graders) introductory chemistry experiments to spread interest in the sciences. 2012-2014

Perform very elementary chemistry demos to preschool students 2014-2016 ACADEMIC HONORS- NEW YORK UNIVERSITY

• Margaret Strauss Kramer Graduate Fellowship in Chemistry, $18,000 for research and an additional $5,000 to be used for materials and supplies 2016-2017 ACADEMIC HONORS- SUSQUEHANNA UNIVERSITY

• Susquehanna Valley Chapter American Chemical Society Outstanding College Chemist Award Recipient 2012

• Outstanding Senior Chemist 2012

• Dean’s List from 2008-2012

• Valedictorian Scholarship $15,000/yr 2008-2012

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• Arthur Scholarship $3750/yr 2008-2012

• Ruth Botdorf Scholarship $2500 (Awarded to one female chemistry major) 2011

• Stephen Bufton Memorial Education Fund recipient 2010 and 2011

• 1st Place Winner at Juniata College Landmark Symposium in 2010

• Polyed Undergraduate Award winner for achievements in Organic Chemistry, 2010

• Named University Scholar (minimum 3.75 GPA) in 2008, 2009, and 2010 ACADEMIC CLUBS/MEMBERSHIPS

Member, Iota Sigma Pi 2016-Present

Honor society for women in chemistry, NYC Vandium Chapter Member, Scientific Entrepreneurs Society NYU 2016-Present Chemist’s Club, NYU 2012-Present

Student Member, American Chemical Society 2010-Present Member, American Business Women’s Association 2010-Present Member, Beta Beta Beta 2009-2012

Biological Honor Society for students dedicated to improving biological study. Vice President, Gamma Sigma Epsilon Chemistry Fraternity 2011-2012 Responsible for organizing meetings and inducting new members. Candidates must have an academic rank in the upper 10 percent of their class. President and Member, Susquehanna University Chemical Society 2008-2012 President (Spring 2011-2012)

Responsible for organizing bi-weekly meetings, tutoring sessions for underclassmen, educational field-trips, and all paperwork required for the club. Member, Alpha Lambda Delta 2008-2012

National Honor Fraternity for freshman with a minimum GPA of 3.75/4.00. Senior Friends 2008-2010

Service club: Would visit with the mentally impaired elderly once a week.

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