Jean Carol Baum

*** * ****** ** #*

Arcadia, Ca, 91007

Cell Phone: 805-***-****

Email: acxirx@r.postjobfree.com

QUALIFICATIONS

** ***** ********** ** ******* research and development of small molecule pharmaceuticals.

6 years experience organic synthesis of small molecules and polymers.

EDUCATION

19972001

M.S. Chemistry, Department of Chemistry and Biochemistry, University of California, Los Angeles.

19861990

B.S. Mechanical Engineering, University of California, San Diego.

EXPERIENCE

2012 present

Chemist, Process Research and Development Dept., Norac Pharma.

Part of the PR&D team in a contract manufacturing pharmaecutical company responsible for developing

processes for delivery of active pharmaceutical ingredients and intermediates. Experienced in handling

controlled substances and potent compounds. Synthesized small molecules and bioconjugate peptides.

20012011

Process Chemist, Chemical Process Research and Development, Amgen Inc.

Synthesized small molecule pharmaceuticals and intermediates for scaleup in a GMP/GLP facility.

Promoted in 2002 and 2009 up to Senior Associate Scientist.

19972001

Research Assistant, Department of Chemistry and Biochemistry, University of California, Los Angeles, Dr. Robin

Garrells research group.

Worked in a surface chemistry lab synthesizing organic small molecules for reaction and characterization

on selfassembled monlayers.

19972000

Teaching Assistant, Department of Chemistry and Biochemistry, University of California, Los Angeles.

Taught General Chemistry and Organic Chemistry Laboratory.

19921997

Laboratory Technician, Fluorochem, Inc., Azusa, CA.

Synthesized organic small molecules and performed reactions on polymers.

Optimized conditions for largescale synthesis on scales up to 50 L.

Operated 50 gallon Pfaudler pressure reactor.

SKILLS

Process development and process research of small molecules for GLP/GMP production.

Characterization by HPLC, mass spectroscopy, TLC, NMR, and FTIR.

Quantitative analysis by HPLC and QNMR to determine mass balance and product purity.

Purification by recrystallization, distillation, silica gel column chromatography, and preparative scale TLC.

Development of crystallizations via solubility analysis and Process Analytical Technology (PAT).

Solid state polymorph analysis by DSC, microscope, and XRPD.

Collaboration with Engineers, Analytical Chemists, and Pharmaceutical Chemists.

Synthesis of bioconjugate polymers and purification by tangential flow filtration.

PUBLICATIONS

Baum, Jean C. Milne, Jacqueline. An Efficient and Scalable Ritter Reaction for the Synthesis of

tertButyl Amides, Organic Synthesis 201*-**-******.

Baum, Jean C. Milne, Jacqueline E. Murry, Jerry A. Thiel, Oliver R. An Efficient and Scalable Ritter

Reaction for the Synthesis of tertButyl Amides, Abstracts of Papers, 240th ACS National Meeting,

Boston, MA, United States, August 2226, 2010.

Baum, Jean C. Milne, Jacqueline E. Murry, Jerry A. Thiel, Oliver R. An Efficient and Scalable Ritter

Reaction for the Synthesis of tertButyl Amides, Journal of Organic Chemistry 2009 74(5) 22072209.

Andersen, Denise Storz, Thomas Liu, Pingli Wang, Xin Li, Leping Fan, Pingchen Chen, Xioqi

Allgeier, Alan Burgos, Alain Tedrow, Jason, Baum, Jean Chen, Ying Crockett, Rich Huang, Liang

Syed, Rashid Larsen, Robert D Martinelli, Mike. Stereoselective Synthesis of a MCHr1 Antagonist,

Journal of Organic Chemistry 2007 72(25), 96489655.

Andersen, Denise L. Liu, Pingli Storz, Thomaz Wang, Xin Allgeier, Alan Baum, Jean Chen, Ying

Crockett, Rich Huang, Liang Larsen, Robert D. Martinelli, Mike. Practical Route to a

MelaninConcentrating Hormone Receptor 1 (MCHr1) Antagonist,: Abstracts of Papers, 234th ACS

National Meeting, Boston, MA, United States, August 1923, 2007.

Liu, Pingli Huang, Liang Lu, Yuelie Dilmeghani, Mina Baum, Jean Xiang, Tingjian Adams, Jeff

Tasker, Andrew Larsen, Rob Faul, Margaret M. Synthesis of Heterocycles via Ligandfree palladium

Catalyzed Reductive Heck Cyclization, Tetrahedron Letters 2007 48(13): 23072310.

Wang, Xin Zhi, Ben Baum, Jean Chen, Ying Crockett, Richard Huang, Liang Eisenberg, Shawn Ng,

John Larsen, Robert Martinelli, Mike Reider, Paul. A Practical Synthesis of

2((1HPyrrol[2,3b]pyridine4yl)methylamino)5Fluoronicotinic Acid. Journal of Organic Chemistry

2006 71(10): 40214023.

Larsen, Robert D. Lu, Yuelie Xiang, Tingjian Zhi, Ben Baum, Jean Liu, Pingli Huang, Liang Chen,

Ying Wang, Xin Crockett, Richard Overland, Doug Schulz, Craig Eisenberg, Shawn Martinelli,

Michael. Development of Practical Syntheses of VEGFR Inhibitors, Abstracts of Papers, 231st ACS

National Meeting, Atlanta, GA, United States, March 2630, 2006.

Baum, J. Fox, M. Garrell, R.L. Bis(Epoxyalkyl) and Epoxyalkyl Glycosylalkyl Disulfides: Synthesis

and Incorporation into SAMS for Molecular Recognition and Controlled Cell Adhesion. Pacifichem,

2000, Honolulu, Hawaii, United States, December 1419, 2000.

Baum, Kurt Baum, Jean C. Ho, Tai. SideLoop Polymers Based on the Hydrosilylation of

Polybutadiene, Journal of the American Chemical Society 1998 120(13): 29932996.

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