D A V I D A. S C A D U T O

** ***** ******, *******, *** York 11769 631- 7 07 - 3 951 acx3qn@r.postjobfree.com 1/6

EDUCATION

STONY BROOK UNIVERSITY College of Engineering and Applied Sciences Candidate for Doctor of Philosophy, Biomedical Engineering September 2010 – Present Dissertation: Clinically Translating Contrast-Enhanced X-ray Breast Imaging Master of Science, Biomedical Engineering May 2012 CAMPEP-Accredited Graduate Program in Medical Physics BOSTON UNIVERSITY College of Engineering

Bachelor of Science, Biomedical Engineering May 2009 RELEVANT COURSEWORK

Radiation Physics

Radiobiology

Medical Health Physics

Medical Imaging Physics

Radiation Oncology Physics

BOARD CERTIFICATION & LICENSURE

Successfully completed Part 1 of the American Board of Radiology examination in Medical Physics in August 2012

AWARDS AND HONORS

Boston University Outstanding Service Award, 2009

Boston University Scarlet Key Society

MEMBERSHIPS AND ASSOCIATIONS

American Association of Physicists in Medicine

Member, Tomosynthesis Subcommittee

Member, Task Group No. 245: Tomosynthesis Quality Control

Member, Website Editorial Committee

Radiological Society of North America

D A V I D A. S C A D U T O

17 Trout Street, Oakdale, New York 11769 631- 7 07 - 3 951 acx3qn@r.postjobfree.com 2/6

PUBLICATIONS & PROCEEDINGS

1. Hu Y-H, Scaduto DA, Zhao W. Optimization of contrast enhanced breast imaging: Analysis using a cascaded linear system model. Med Phys. In press.

2. Scaduto DA, Hu Y-H, Lu Y, et al. Dependence of Contrast-Enhanced Lesion Detection in Contrast- Enhanced Digital Breast Tomosynthesis on Imaging Chain Design. In: Tingberg A, Lång K, eds. Breast Imaging. Malmo, Sweden: Springer Berlin Heidelberg; 2016. 3. Scaduto DA, Yang M, Ripton-Snyder J, Fisher PR, Zhao W. Digital breast tomosynthesis with minimal breast compression. In: Hoeschen C, Kontos D, Flohr TG, eds. SPIE Medical Imaging. Vol 9412. Orlando, FL: International Society for Optics and Photonics; 2015:94121Y. doi:10.1117/12.2081543.

4. Lu Y, Peng B, Lau BA, Hu Y-H, Scaduto DA, et al. A scatter correction method for contrast-enhanced dual-energy digital breast tomosynthesis. Phys Med Biol. 2015;60(16):6323-6354. doi:10.1088/0031- 9155/60/16/6323.

5. Scaduto DA, Lubinsky AR, Rowlands JA, et al. Investigation of spatial resolution and temporal performance of SAPHIRE (scintillator avalanche photoconductor with high resolution emitter readout) with integrated electrostatic focusing. In: Whiting BR, Hoeschen C, eds. SPIE Medical Imaging. Vol 9033. ; 2014:90333S. doi:10.1117/12.2043187. 6. Lu Y, Peng B, Scaduto DA, Zhao W, Gindi G. Application of the Ordered-Subsets Transmission Reconstruction Algorithm to Contrast-Enhanced Dual-Energy Digital Breast Tomosynthesis. In: Proc. IEEE Nuclear Science Symposium and Medical Imaging Conference IEEE NSS/MIC. Seattle, WA; 2014.

7. Hu Y-H, Scaduto DA, Zhao W. Optimization of clinical protocols for contrast enhanced breast imaging. In: Nishikawa RM, Whiting BR, eds. SPIE Medical Imaging. Orlando, FL: International Society for Optics and Photonics; 2013:86680G. doi:10.1117/12.2008028. 8. Scaduto DA, Zhao W. Determination of System Geometrical Parameters and Consistency between Scans for Contrast-Enhanced Digital Breast Tomosynthesis. In: Maidment ADA, Bakic PR, Gavenonis S, eds. Lecture Notes in Computer Science. Vol 7361 LNCS. Lecture Notes in Computer Science. Berlin, Heidelberg: Springer Berlin Heidelberg; 2012:24-31. doi:10.1007/978-3-642-31271-7_4. 9. Hu Y-H, Scaduto DA, Zhao W. The Effect of Amorphous Selenium Thickness on Imaging Performance of Contrast Enhanced Digital Breast Tomosynthesis. In: Maidment ADA, Bakic PR, Gavenonis S, eds. Lecture Notes in Computer Science. Vol 7361 LNCS. Lecture Notes in Computer Science. Berlin, Heidelberg: Springer Berlin Heidelberg; 2012:9-16. D A V I D A. S C A D U T O

17 Trout Street, Oakdale, New York 11769 631- 7 07 - 3 951 acx3qn@r.postjobfree.com 3/6

ORAL PRESENTATIONS

Annual Meeting of the American Association of Physicists in Medicine, 2016 Measuring Spatial Resolution in Digital Breast Tomosynthesis: Update of AAPM Task Group 245.

July 2016

Washington, DC, USA

SPIE Medical Imaging, 2015

Digital breast tomosynthesis with minimal breast compression. February 2015

Orlando, FL, USA

Annual Meeting of the American Association of Physicists in Medicine, 2014 Increasing Amorphous Selenium Thickness in Direct Conversion Flat-Panel Imagers for Contrast-Enhanced Dual-Energy Breast Imaging. July 2014

Austin, TX, USA

11th International Workshop on Breast Imaging

Determination of System Geometrical Parameters and Consistency between Scans for Contrast-Enhanced Digital Breast Tomosynthesis. July 2012

Philadelphia, PA, USA

POSTER PRESENTATIONS

13th International Workshop on Breast Imaging

Determination of System Geometrical Parameters and Consistency between Scans for Contrast-Enhanced Digital Breast Tomosynthesis. June 2016

Malmö, Sweden

SPIE Medical Imaging, 2014

Investigation of spatial resolution and temporal performance of SAPHIRE (scintillator avalanche photoconductor with high resolution emitter readout) with integrated electrostatic focusing. February 2014

San Diego, CA, USA

CLINICAL EXPERIENCE

STONY BROOK MEDICINE Department of Radiation Oncology January – May 2012

Completed 120-hour clinical practicum with radiation oncology physicists

Observed and participated in LINAC, HDR and IMRT quality assurance procedures

Assisted with photon/electron beam calibrations, related calibrations and acceptance testing

Attended weekly department case-review session with physicians, physicists and dosimetrists D A V I D A. S C A D U T O

17 Trout Street, Oakdale, New York 11769 631- 7 07 - 3 951 acx3qn@r.postjobfree.com 4/6

RESEARCH

STONY BROOK UNIVERSITY Department of Radiology September 2010 – Present Dissertation: Clinically Translating Contrast-Enhanced X-ray Breast Imaging Advisor: Wei Zhao, Ph.D.

Abstract: Contrast-enhanced digital mammography (CEDM) and digital breast tomosynthesis (CEDBT) are radiographic breast imaging techniques currently being investigating to improve the diagnosis of breast cancer. While initial studies of these methods have shown promising results, the techniques remain nascent and are immature for clinical adoption. This work aims to address problems at several stages of the clinical translational pathway. Methods and metrics to evaluate performance and consistency of digital breast tomosynthesis for clinical imaging and contrast-enhanced applications are developed. Improvements to mammographic x-ray detector performance are investigated for low- dose imaging and contrast-enhanced breast imaging applications. Imaging techniques are developed and evaluated to reduce requisite breast compression to facilitate contrast medium perfusion in the breast. Finally, the feasibility of CEDM and CEDBT for improved breast cancer diagnosis is demonstrated in clinical patient studies.

Determination of system geometrical parameters for contrast-enhanced digital breast tomosynthesis

Developed a geometrical calibration technique for digital breast tomosynthesis systems using pose estimation through projective geometry

Determined geometrical system parameters of prototype tomosynthesis unit and evaluated geometrical reproducibility using calibration algorithm

Designed new calibration phantom for easier and more accurate system characterization

Presented findings at 11th International Workshop on Breast Imaging in 2012 Development of quality control metrics and procedures for digital breast tomosynthesis

Working with AAPM Task Group No. 245 to develop and test performance metrics for digital breast tomosynthesis

Collaborate with phantom manufacturers, digital breast tomosynthesis system manufacturers and academic medical centers to evaluate developed phantoms and tools

Analyze data acquired at Stony Brook Medicine and other academic medical centers

Communicate results with Task Group, manufacturers

Presented update of Task Group at Annual Meeting of AAPM in 2016 D A V I D A. S C A D U T O

17 Trout Street, Oakdale, New York 11769 631- 7 07 - 3 951 acx3qn@r.postjobfree.com 5/6

Investigation of spatial resolution and temporal performance of SAPHIRE with integrated electrostatic focusing

Investigated imaging performance of prototype sensor fabricated by industrial collaborators

Consulted on experimental evaluation of sensor

Authored software to analyze acquired data

Presented findings at SPIE Medical Imaging in 2014 Imaging performance of a direct conversion amorphous selenium detector with thicker conversion layer for dual-energy contrast-enhanced breast imaging

Authored new and updated existing software to characterize x-ray detector detective quantum efficiency (DQE) according to IEC 62220-1 Standard

Evaluated DQE of commercial and prototype x-ray detectors for digital breast tomosynthesis

Implemented mathematical model to predict characteristics of prototype x-ray detectors

Presented findings at Annual Meeting of AAPM in 2014 Development of imaging technique for DBT with reduced breast compression

Developed imaging technique for digital breast tomosynthesis to maintain image quality, radiation dose while reducing breast compression

Implemented mathematical model to investigate imaging technique

Evaluated imaging technique in phantom, clinical studies

Presented findings at SPIE Medical Imaging in 2015 Investigation of dual-energy subtraction techniques for contrast-enhanced digital breast tomosynthesis

Designed various imaging chains for contrast-enhanced digital breast tomosynthesis

Evaluated lesion detectability for each imaging chain in phantom and patient images

Presented findings at the 13th International Workshop on Breast Imaging in July 2016 BOSTON UNIVERSITY Department of Biomedical Engineering September 2008 – May 2009 Design of an Anatomical Ultrasound Simulator

Researched and developed an inexpensive, computer-based diagnostic ultrasound simulation system for use by clinicians in underserved communities and developing countries

Created project proposal detailing background, methodology, budget and timeline

Drafted incremental team progress reports detailing project status and complications

Prepared comprehensive final report, and presented to academic and industrial community at Boston University Biomedical Engineering Senior Conference in May 2009 D A V I D A. S C A D U T O

17 Trout Street, Oakdale, New York 11769 631- 7 07 - 3 951 acx3qn@r.postjobfree.com 6/6

TEACHING EXPERIENCE

Taught history and fundamentals of mammography in graduate medical imaging course

Lectured undergraduate radiology technologist students on fundamentals of computed tomography

Presented lecture on the history and state of art of portal imaging in radiation oncology

Periodically present research at international scientific conferences

Regularly communicate results of research projects to interdepartmental breast tomosynthesis interest group

EMPLOYMENT EXPERIENCE

Research Foundation of State University of New York September 2010 – Present Graduate Research Assistant

Engage in a variety of independent and collaborative research projects related to digital breast tomosynthesis and contrast-enhanced breast imaging

Develop MATLAB code to model x-ray physics phenomena, design imaging schemes, analyze imaging system performance characteristics and process patient images from clinical studies

Author clinical research protocols, maintain all submissions and related documents and ensure research studies comply with Institutional Review Board and ethical standards

Collaborate with researchers from various laboratories, companies

Regularly communicate results and conclusions to colleagues, academic and industrial collaborators

Vision Quest Lighting Inc. February 2010 – August 2010 Project Manager for Translational Inventory Control

Planned and managed material requirements for manufacture of custom lighting for national retail chains

Managed relocation of factory to new facility, coordinating construction of stock room and material relocation

Directed annual inventory count of over 4,000 active parts, totaling over $1.6 million REFERENCES

Wei Zhao, Ph.D., Stony Brook University: acx3qn@r.postjobfree.com, 631-***-**** Terry M. Button, Ph.D., Stony Brook University: acx3qn@r.postjobfree.com, 631-***-**** Gene Gindi, Ph.D., Stony Brook University: acx3qn@r.postjobfree.com, 631-***-**** Paul R. Fisher, M.D., Stony Brook Medicine: acx3qn@r.postjobfree.com, 631-***-****

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