HPLC, GC, NMR

Curriculum Vitae

Name: Deepa Krishnan

Email: *****.**********@*****.***

Cell phone: 614-***-****

Telephone: 614-***-****

Citizenship: India/US Permanent Resident since July 2016 Summary

Obtained research experience with more than six years in industrial and academic environments conducting high level scientific research. Skilled chemist with comprehensive applied background in LCMS, HPLC and GC techniques.

Education

C# & ASP – DOTNET Application (2013)

Chennai IT Training Solutions (CITS), (A Grade) Chennai, India Doctor of Philosophy in Chemistry (2007–2012)

NANYANG TECHNOLOGICAL UNIVERSITY, Singapore

Master of Science in Applied Chemistry (2002–2004) ANNA UNIVERSITY, Chennai, India

Bachelor of Science in General Chemistry (1999–2002) UNIVERSITY OF MADRAS (MEENAKSHI COLLEGE FOR WOMEN), India Technical Proficiency

Liquid chromatography mass spectrometry (LCMS)

High Resolution Mass Spectrometry (HRMS)

High pressure liquid chromatography (HPLC)

Gas Liquid chromatography (GC)

Nuclear Magnetic Resonance (Bruker & JEOL) spectrometry (NMR)

Fluorescence and UV-Visible spectrometry

FTIR spectrometry

Atomic Absorption Spectrometry

Titration Techniques

Research Experience

Doctoral Research Project:

Designed and conducted research on synthesis of cyclo-metallated sulfur and nitrogen-N- Heterocyclic carbene complexes and their application in catalysis.

Investigated on design and synthesis chiral N-heterocyclic carbene ligands, palladium and platinum NHC scaffolds for asymmetric catalytic reactions.

Analyzed, stereochemical investigation of NHC compounds in both solid and solution state with complete structural characterization using wide range of experimental techniques including 2D ROESY, HMBC, HMQC, VT-NMR, XRD techniques. Deepa Krishnan: Resume, 2016

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Evaluated the catalytic activity of newly developed functionalized N-Heterocyclic carbene complex for reactions mainly focused on [2,3]-Sigmatropic rearrangement, allylic amination, allylic alkylation, Diels Alder reactions.

Master of Science Research Project:

“[(L)-Proline]2Zn Catalyzed synthesis of 1,5-benzodiazepene derivatives under solvent free condition”.

Developed and synthesized a series of Lewis acid Zn-complexes.

Executed an efficient one pot synthesis of 1,5-benzodiazepene derivatives using [(L)- Proline]2Zn catalyst through both conventional and microwave irradiation methods and evaluated a recycling catalytic studies on Zinc proline complex. Industrial Experience

Research Associate in Aurigene Discovery Technologies Ltd Bangalore, India (2004–2007)

Successfully demonstrated the synthesis, purification and characterization of novel 5- substituted indole derivatives as Dipeptidyl Peptidase IV (DPP-IV) inhibitors.

Efficiently Optimize multi-step routes, chemical derivatization methods for targeted small molecule on milligram scale and delivered quality compounds by organic synthesis for biological testing.

Repeatedly proved continuous productivity on working in internal team with contract research organization and delivered compounds by organic synthesis with a wide variety of techniques, including libraries, key intermediates and scale up in required qualities and time lines.

Regularly produced solutions to synthetic challenges and maintained complete and accurate scientific records.

Achievements

Best Project Award for Dipeptidyl Peptidase IV (DDP–IV) team (2006) Aurigene Discovery Technologies Limited, Bangalore, India Teaching Experience

Division of Chemistry and Biological Chemistry, NTU Singapore (2007–2012)

Mentor to Undergraduate students:

Supervised and evaluated the performance of undergraduate students (7) - summer research, final year projects (FYP) in synthetic organic and organometallic chemistry.

Facilitated learning and improved performance by training students individually.

Evaluated highly by the students for stimulating independent thinking and demonstrating an interest in them.

Teaching Assistant [Analytical, Inorganic and Organic Chemistry lab sessions]:

Aided students in handling various analytical instruments.

Trained safe handling of general laboratory techniques.

Given emphasis to keep complete and accurate scientific notes.

Addressed each individual student’s questions and needs. Deepa Krishnan: Resume, 2016

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Other Proficiency

MS–Office

C# & ASP–DOTNET Application

Sci-Finder, PubMed, Scopus & Web of science

Crystal Molecular Structure Visualization analysis

ChemBioDraw Ultra

Endnote X6

Training

Fire safety training in chemistry laboratory, Aurigene Discovery Technologies Ltd (2005)

LCMS, NMR Training, Division of Chemistry & Biological Chemistry, NTU (2007) Presentations

International Symposium on Catalysis and Fine Chemicals (C&FC) Singapore (2007)

UK-Singapore Symposium on Medicinal Chemistry, Biopolis Singapore (2008, 2010) Publications

1. Deepa Krishnan., Sumod A. Pullarkat., Meiyi Wu., Yongxin Li., Pak-Hing Leung (2013). Synthesis, Structural Characterizations and Stereochemical Investigations of Chiral Sulfur-N- Heterocyclic Carbene Complexes of Palladium and Platinum. Chemistry - A European Journal, 19(17), 5468–75 (Impact Factor: 5.771).

2. Deepa Krishnan., Meiyi Wu., Minyi Chiang., Yongxin Li., Sumod A. Pullarkat., and Pak-Hing Leung (2013). N-Heterocyclic Carbene C,S Palladium(II) π-Allyl Complexes : Synthesis, Characterization and Catalytic Application In Allylic Amination Reaction. Organometallics, 32(8), 2389–97 (Impact Factor: 4.253).

3. Minyi Chiang., Yongxin Li., Deepa Krishnan., Sumod A. Pullarkat., Kim Hong Ng., Pak-Hing Leung (2010). Synthesis and Characterisation of a Novel Chiral Bidentate Pyridine-N- Heterocyclic carbene-based Palladacycles. European Journal of Inorganic Chemistry, 9, 1413–18 (Impact Factor: 2.965).

4. Mingjun Yuan., Sumod A. Pullarkat., Crystal Huixian Yeong., Yongxin Li., Deepa Krishnan and Pak Hing. Leung (2009). Controllable Synthesis of P-chiral 1,2– and 1,3–diphosphines via asymmetric Diels–Alder Reactions Involving Functionalized Allylic Phosphines as Dienophiles, Dalton Transactions, 3668–70 (Impact Factor: 4.177). 5. Sivamurugan V., Deepa Krishnan., Murugesan V. (2004). [(L)–Proline]2Zn Catalyzed Synthesis of 1, 5–Benzodiazepine Derivatives under Solvent-Free Condition. Synthetic Communications, 34(21), 3833–46 (Impact Factor: 1.062).

“Reference will be provided upon request”

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