Biostatistician

Location:

Flower Mound, TX

Posted:

August 17, 2016

Contact this candidate

Resume:

Hyunsu Ju, Ph.D.

Biostatistician II

Heart/Lung Transplant and Pulmonary Research

Annette C. and Harold C. Simmons Transplant Institute

Baylor University Medical Center

**** ***** ******, ***** 560

Dallas, TX 75246

Phone: 214-***-****

Fax: 214-***-****

Email: *******@*****.***

CURRENT PROFESSIONAL POSITION & EMPLOYMENT HISTORY

2016 - Present Biostatisician II, Baylor University Medical Center at Dallas

2005- 2016 Assistant Professor, Sr. Biostatistician

Department of Preventive Medicine and Community Health

University of Texas Medical Branch, Galveston, TX

EDUCATION

1999 – 2004 Ph.D., Statistics

Dissertation: Topics in Analyzing Longitudinal Data,

Texas A&M Univeristy, College Station, TX

Dissertation Chair: Suojin Wang, Ph.D.

1996 – 1998 M.S., Statistics

Thesis : Study on Mantel-Haenszel Homogeneity tesing procedure,

Seoul National University, Seoul, Korea

1989 – 1996 B.S., Applied Statistics

Chung-Ang University, Seoul, Korea

PROFESSIONAL EXPERIENCE

• Provide biostatistical input on interdisciplinary project teams

• Involve protocol reviews in UTMB Institutional Animal Care and Use Committee (IACUC)

• Collaborate with Investigators, performed statistical analyses and serves as coauthor on collaborative manuscripts

• Conduct statistical research and give presentations in professional meetings participated in writing statistical analysis plans for various grant applications

• Create and manage multiple large data sets using Windows SAS (Seer Medicaid/Medicare, Clinical informatics, NHANES, Hispanic EPESE study

• Perform sample size calculations and writes statistical analysis plans and statistical data analyses for multiple projects (longitudinal data analysis, mixed models, chi-square procedures, logistic regression, factor analysis, etc)

RESEARCH INTERESTS

Hidimensional Data, Data Mining, Variable Selection and Classification, Longitudinal Data,

Linear Mixed Model, Survival Model via Semiparametric and Nonparametric estimation,

Multi-level model and Bootstrap methodology.

Advanced Statistical Methods (SAS, SPSS, STATA, R, Matlab, WinBugs)

US PATENT APPLICATIONS

US Patent Application US 2013/0004473 A1, Jan. 3, 2013 “Method and Biomarkers for the

Detection of Dengue Hemorrhagic Fever”

US Patent Application US 2014/022510 Oct. 9, 2014 “Biomarkers for chagas disease related

cardiomyopathy”

US Patent Application US 2015 Oct.1, 2015 “Methods and Compositions for identifying

pulmonary aspergillosis”

PUBLISHED ARTICLES IN PEER-REVIEWED JOURNALS

1.Buchanan RJ, Wang S, Ju H, Graber D. Analyses of gender difference in profiles of nursing home residents with Alzheimer's disease. Gender Medicine 2004; 1:48-59.

2.Buchanan RJ, Chakravorty B, Wang S, Ju H, Hackethorn, D. Nursing home residents with emphysema/COPD compared to other residents. J Social Work in Disability & Rehab 2004; 3:53-78.

3.Buchanan RJ, Choi MA, Wang S, Ju H. End of life care in nursing homes: residents in hospice compared to other end stage residents. J Palliative Medi 2004; 7:221–32.

4.Buchanan RJ, Martin RA, Wang S, Ju H. Analyses of nursing home residents with MS at admission and one year after admission. Multiple Sclerosis 2004;10:74-9.

5.Buchanan RJ, Martin RA, Moore L, Wang S, Ju H. Nursing home residents with MS and dementia compared to other MS residents. Multiple Sclerosis 2005;11:610-6.

6.Buchanan RJ, Wang S, Ju H. Nursing home residents with Alzheimer's disease in special care units compared to other residents with Alzheimer's disease. Dementia: Intl J Soc Res and Prac 2005; 4:249-67.

7.Buchanan RJ, Wang S, Martin RA, Ju H. Utilization of rehabilitation therapies by nursing home residents with MS at admission. NeuroRehabilitation 2006;21(3):178-87.

8.Lui CY, Ju H. Impact of Enzyme Replacement Therapy on Cardiac Morphology and Function and Late Enhancement in Fabry’s Cardiomyopathy. Readers’ Comments. Am J Cardiol 2006; 98:1557-8.

9.Stimpson JP, Ju H, Raji MA, Eschbach K. Neighborhood deprivation and health risk behaviors in NHANES III. Am J Health Behavior 2007 Mar; 31(2):215-22.

10.Stimpson JP, Nash AC, Ju H, Eschbach K. Neighborhood deprivation is associated with lower levels of serum carotenoids among adults participating in the Third National Health and Nutrition Examination Survey. J Am Diet Assoc 2007 Nov;107(11):1895-902.

11.Koo ST, Lim GS, Jung KS, Ju H, Jung JM. Electroacupuncture-induced analgesia in a rat model of ankle sprain pain is mediated by spinal alpha-adrenoceptors. Pain 2008 Mar; 135(1-2):11-9.

12.Brasier AR, Victor S, Boetticher G, Ju H, Lee C, Bleecker ER, Castro M,Busse WW, Calhoun WJ. Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage-derived cytokines. J Allergy Clin Immunol 2008 Jan;121(1):30-37.e6.

13.Raji MA, Tamborello LP, Kuo YF, Ju H, Freeman JL, Zhang DD, Giordano SH, Goodwin JS. Risk of subsequent dementia diagnoses does not vary by types of adjuvant chemotherapy in older women with breast cancer. Med Oncol 2009 Dec;26(4):452-459.

14.Reyes-Ortiz CA, Ju H, Eschbach K, Kuo YF, Goodwin JS. Neighbourhood ethnic composition and diet among Mexican-Americans. Public Health Nutr 2009 Mar; 12:2293-2301.

15.Reyes-Ortiz CA, Ju H, Inniss A, Eschbach K, Kuo YF, Goodwin JS. Acculturation and serum nutrients thought to be involved with cancer prevention among Mexican American men in the United States. Cancer Control: Journal of the Moffitt Cancer Center 2009 Apr;16(2):169-75.

16.Allan R. Brasier, Sundar Victor, Hyunsu Ju, William W. Busse, Douglas Curran-Everett,Eugene Bleecker, Mario Castro, Kian Fan Chung, Benjamin Gaston, Elliot Israel, Sally E. Wenzel, Serpil C. Erzurum, Nizar N. Jarjour and William J. alhoun. Predicting Intermediate Phenotypes in Asthma Using Bronchoalveolar Lavage-Derived Cytokines. Clinical and Translational Science 2010 Aug;3(4)147-257.

17.John R. Petersena, Felix O. Omoruyib, Amin A. Mohammadc, Thomas J. Sheaa, Anthony O. Okorodudua and Hyunsu Ju. Hemoglobin A1c: Assessment of Three POC Analyzers Relative to a Central Laboratory Method. Clinica Chimica Acta 12/2010;411(23-24):2062-6.

18.Norma Perez, Luisa Franzini, Daniel H. Freeman, Hyunsu Ju and Kristen Peek. A Population-Based Study of Job Stress in Mexican Americans, non-Hispanic Blacks, and non-Hispanic Whites. Hispanic Journal of Behavioral Sciences 2011 33: 221.

19.Malcolm P Cutchin, Karl Eschbach, Christine A Mair, Hyunsu Ju, James Goodwin. (2011). The socio-spatial neighborhood estimation method: An Approach to operating the neighborhood concept. Health & Place 2011 Jun 7; 17(5):1113-21.

20.Suresh K. Bhavnani, Sundar Victor, William J. Calhoun, William W. Busse, Eugene Bleecker, Mario Castro, Hyunsu Ju, and Allan R. Brasier.(2011) How Cytokines Co-occur across Asthma Patients: From Bipartite Network Analysis to a Molecular-Based Classification. Journal of Biomedical Informatics 12/2011;44 Suppl 1:S24-30.

21.Allan R Brasier, Hyunsu Ju, Josefina Garcia, Heidi M. Spratt, Sundar S., Victor, Brett M. Forshey, Eric S. Halsey, Guillermo Comach, Gloria Sierra, Patrick J. Blair, Claudio Rocha, Amy C. Morrison, Thomas W. Scott, Isabel Bazan, Tadeusz J. Kochel, and the Venezuelan Dengue Fever Working Group. A Three-Component Biomarker Panel For Prediction Of Dengue Hemorrhagic Fever, Am J Trop Med Hyg, 02/2012; 86(2):341-8.

22.Allan R Brasier, Josefina Garcia, John E. Wiktorowicz, Heidi M. Spratt, Guillermo Comach, Hyunsu Ju, Adrian Recinos III, Kizhake Soman, Brett M. Forshey, Eric S. Halsey, Patrick J. Blair, Claudio Rocha, Isabel Bazan, Gloria Sierra, Iris Chacon, Carlos Espino, Sundar S Victor, Zheng Wu, Susan Stafford, and Douglas Watts, Amy C. Morrison, Thomas W. Scott and Tadeusz J. Kochel. Discovery proteomics and nonparametric modeling pipeline in the development of a candidate biomarker panel for dengue hemorrhagic fever. Clinical and Translational Science, 2012 Feb;5(1):8-20.

23.Markides KS, Al Snih S, Walsh T, Cutchin M, Ju H, Goodwin JS Problem drinking among Mexican Americans: The influence of acculturation, nativity, and neighborhood context? American Journal of Health Promotion: March 2012, Vol. 26, No. 4, pp. 225-229.

24.Celeste C. Finnerty, Hyunsu Ju, Heidi Spratt, Sundar Victor, Marc G. Jeschke, Sachin Hegde, Bruce A. Luxon, Allan R. Brasier and David N. Herndon. Proteomics Improves the Prediction of Burns Motality: Results from Regression Spline Modeling. Clinical and Translational Science, 06/2012; 5(3):243-9.

25.Lee-Jane W Lu, Thomas K Nishino, Raleigh F Johnson,Fatima Nayeem, Donald G Brunder, Hyunsu Ju, Morton H Leonard Jr, James J Grady and Tuenchit Khamapirad. Comparison of breast tissue measurements using magnetic resonance imaging, digital mammography and a mathematical algorithm. Physics Medicine Biology, 10/2012; 57(21):6903-27.

26.Heidi Spratt, Hyunsu Ju and Allan R. Brasier, A structured approach to predictive modeling of a two-class problem using multidimensional data sets. Methods, 2013 May;61(1):73-85.

27.Hyunsu Ju, Allan R. Brasier, Variable selection methods for developing a biomarker panel for prediction of dengue hemorrhagic fever. BMC Research Notes 09/2013 6(1):365.

28.Mehnaz G. Mustafa, John R. Petersen, Hyunsu Ju, Luca Cicalese, Ned Snyder, Sigmund J Haidacher, Larry Denner, and Cornelis Elferink. Biomarker Discovery for Early Detection of Hepatocellular Carcinoma (HCC) in Hepatitis C (HCV) Infected Patients. Molecular & Cellular Proteomics, 2013 Dec;12(12):3640-52.

29.Allan R. Brasier, Hyunsu Ju, Analysis and Predictive Modeling in Asthma Phenotypes, In Heterogeneity in Asthma”, Allan R. Brasier (Ed.), Springer, (ebook, 10/2013), Springer US press, 795: 273-88.

30.Lata Kaphalia, Nahal Boroumand, Ju Hyunsu, Bhupendra S. Kaphalia, William J. Calhoun. Ethanol metabolism, oxidative stress and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding, Toxicol Appl Pharmacol 2014 Jun 1;277(2):109-17..

31.Gengming Huang, Joseph D. Krocker, Jason L. Kirk, Lucas R. Wieck, Shehzad N. Merwat, Hyunsu Ju, Roger D. Soloway, Albert Li, Anthony O. Okorodudu, John Petersen, Nihal E. Abdulla, Andrea Duchini, Luca Cicalese, Cristiana Rastellini, Peter C. Hu, Jianli Dong, “Evaluation of INK4A Promoter Methylation using Pyrosequencing and Circulating Cell free DNA from Patients with Hepatocellular Carcinoma”, Clin Chem Lab Med. 2014 Jun;52(6):899-909.

32.Ju, H, Brasier AR, Kurosky A, Xu B, Reyes VE and Graham DG. Diagnostics for statistical variable selection methods for prediction of peptic ulcer disease in helicobacter pylori infection, J Proteomics Bioinform 2014, 7:095-101.

33.Fatima Nayeem, Hyunsu Ju, Donald G. Brunder, Manubai Nagamani, Karl E. Anderson, Tuenchit Khamapirad, and Lee Jane W. Lu. Similarity of Fibroglandular Breast Tissue Content Measured from Magnetic Resonance and Mammographic Images, and by a Mathematical Algorithm. International Journal of Breast Cancer 2014 June 3., Vol. 2014:1-15.

34.Hyunsu Ju, Moving block bootstrap for analyzing longitudinal data. Communications in Statistics – Theory and Methods, 2015;44(6):1130-1142.

35.Allan R. Brasier, Yingxin Zhaoa, John E. Wiktorowicz, Heidi M. Spratt, Eduardo J.M. Nascimentoh, Marli T. Cordeirof,Kizhake V. Soman, Hyunsu Ju, Adrian Recinos III, Susan Stafford,Zheng Wu, Ernesto T.A. Marques Jrf, Nikos Vasilakis. Molecular classification of outcomes from dengue virus -3 infections, Journal of Clinical Virology 2015, 64:97-106

36.Adetoun Ejilemele, Jamie Unabia, Hyunsu Ju, John R. Petersen A1c Gear: Laboratory quality HbA1c measurement at the point of care. Clinica Chimica Acta 2015 Mar 21, 139-142

37.Poonam Desai, Jun Yang, Bing Tian, Hong Sun, Mridul Kalita, Hyunsu Ju, Adriana Paulucci-Holthauzen, Yingxin Zhao, Allan R. Brasier and Rovshan G. Sadygov. Mixed-Effects Model of Epithelial-Mesenchymal Transition Reveals Rewiring of Signaling Networks, Cellular Signalling, 2015, 7:1413-1425

38.Allan R. Brasier, Yingxin Zhao, Heidi M. Spratt, John E. Wiktorowicz, Hyunsu Ju, L. Joseph Wheat, Lindsey Baden, Susan Stafford, Zheng Wu, Nicolas Issa, Angela M. Caliendo, David W. Denning, Kizhake Soman, Cornelius J Clancy, M. Hong Nguyen, Michele Sugrue, Barbara D. Alexander and John R. Wingard. Improved detection of invasive pulmonary aspergillosis arising during leukemia treatment using a panel of host response proteins and fungal antigens, Plos one, 2015,10(11):1-21.

39.Choi S, Huang X, Ju H, Ning J. (2016). Semiparametric joint accelerated intensity models for correlated recurrent and terminal events. Statistica Sinica, In Press

40.Michael Kinsky, Nicole Ribeiro, Maxime Cannesson, Donald Deyo, George Kramer, Michael Salter, Muzna Khan, Hyunsu Ju, William E Johnston. (2016) Peripheral Venous Pressure as an Indicator of Preload Responsiveness During Volume Resuscitation from Hemorrhage, Anesthesia & Analgesia, In Press

41.V-M. Sadagopa Ramanujam, Fatima Nayeem, Karl E. Anderson, Yong-Fang Kuo, Nai-Wei Chen, Hyunsu Ju, and Lee-Jane W. Lu (2016). Riboflavin as a Specific, Sensitive, and Independent Tracer for Adherence to Intervention Agents in a Randomized Double-blind and Placebo-Controlled Clinical Trial, Clinical Pharmacology & Therapeutics, In Press

42.Rachel R. Deer, Jared M. Dickinson, Steven Fisher, Hyunsu Ju, Elena Volpi (2016). Identifying Effective and Feasible Interventions to Accelerate Functional Recovery from Hospitalization in Older Adults: A Randomized Controlled Pilot Trial. Contemporary Clinical Trials, In Press

WORKING PAPERS

1.Modern Proteomics Book Chapter “Statistical Approaches to Candidate Biomarker Panel Selection” Heidi Spratt and Hyunsu Ju

2.Semi-parametric Joint Accelerated Intensity Model for Correlated Recurrent and Terminal events, Sangbum Choi and Hyunsu Ju

3.Mutual Information using Copula Functions in Proteomics, Hyunsu Ju and Jong Min Kim

4.Mixed Linear Models for Heterogeneity in Group Difference, Hyunsu Ju

5.The Effects of Conflict Resolution Skill on Victimization and Perpetration of Dating Violence Among Adolescents, Chorong Kim and Hyunsu Ju

FUNDING RESEARCH ACTIVITY

07/2009 - Current Biostatistician, Co-Investigator.

UTMB Clinical and Translational Science Award

(Allan Brasier, Principal Investigator)

NIH

07/2009 - Current BERD (Biostatistics Epidemiology Research Design) Member

Institutes for Translation Science, UTMB

07/2009 - Current Biostatistician, Co-Investigator.

UTMB NIEHS center in Environmental Toxicology

(Elferink, Cornelis, Principal Investigator)

07/2009-03/2011 Biostatistician, Co-Investigator.

UTMB Clinical Proteomics Centers for Infectious Diseases and

Biodefense

(Allan Brasier, Principal Investigator)

NIH/NIAID

07/2009-08/2010 Biostatistician, Co-Investigator.

UTMB Office of Biostatistics

Effects of Disability on the Diagnosis of Breast Cancer

(Mabel Caban, Principal Investigator)

NIH/NCI

05/2005-8/2009 Biostatistician, Co-Investigator.

UTMB Claude Pepper Older Americans Independence Center

(James S. Goodwin, Principal Investigator).

National Institute on Aging. (P60AG17231)

05/2005-8/2009 Biostatistician, Co-Investigator.

Hispanic Established Population for Epidemiologic Studies of the Elderly.

(Kyriakos Markides, Principal Investigator).

National Institute on Aging. (R01 AG10939)

05/2005-8/2009 Biostatistician, Co-Investigator.

Project 1. Hispanic Neighborhoods and Cancer Risks and Outcomes.

UTMB Center for Population Health and Health Disparities. (James S. Goodwin, MD., Center Principal Investigator) National Cancer Institute (IP50 CA105631-01)

09/2001-12/2004 Graduate Research Assistant, Texas A&M University, College Station,

Texas.

03/1996-08/1999 Research Assistant, Seoul National University, Seoul Korea

TEACHING ACTIVITIES

Summer 2013 Graduate Teaching Instructor (Special Topics Correlated Data Analysis,

Course PHS6396-003)

Spring Semester 2012 Graduate Teaching Instructor (Introduction to linear model, Course PHS

6433) Department of Preventive Medicine and Community Health

The University of Texas Medical Branch, Galveston, Texas

Spring Semester 2011 Graduate Teaching Instructor (Introduction to linear model, Course PHS 6433)

(1/2011-4/30/2011) Department of Preventive Medicine and Community Health

The University of Texas Medical Branch, Galveston, Texas.

06/2006-07/2006 Graduate Teaching Co-Instructor (Longitudinal Data Analysis, Course PHS 6000) The University of Texas Medical Branch, Galveston, Texas.

08/1999-08/2001 Graduate Teaching Assistant, Texas A&M University, College Station,

Texas.

03/1996-08/1999 Graduate Teaching Assistant, Seoul National University, Seoul, Korea.

MEMBERSHIP IN SCIENTIFIC SOCIETIES/PROFESSIONAL ORGANIZATIONS:

1999 - Present Institute of Mathematical Statistics

1999 - Present International Biometric Society Eastern North American Region

1999 - Present American Statistical Association

HONORS & ACHIEVEMENT:

2005 - Current Listed in Marquis’s Who’s Who in the World

1999 - 2000 Regents’ Fellowship, Texas A&M University.

1995 - 1996 Chung-Ang University Undergraduate Fellowship Award in Statistics Department, Chung-Ang University.

1990 - 1994 Undergraduate Scholarships awarded by the College of Politics and

Economics, Chung-Ang University.

ADDITIONAL INFORMATION:

Consulting Experience

03/2009 - Current Director, Biostatistics Facility, Integrative Health Science Facility Core, NIEHS center, UTMB, Galveston, Texas

05/2005 - Current Office of Biostatistics, University of Texas Medical Branch, Galveston, Texas.

08/2002 - 12/2004 Member of the Statistical Consulting Center, Department of Statistics, Texas A&M University, College Station, Texas.

08/1996 - 08/1998 Statistical Consultant at the Biostatistics Consulting Unit founded by SNUCM (Seoul National University, College of Medicine), Seoul National University, Seoul, Korea.

PRESENTATIONS INFORMATION:

08/2015 Title: Copula Modeling for Developing a Biomarker Panel for Prediction of Dengue Hemorrhagic Fever

Location: Joint Statistical Meeting 2015, Seattle, WA

11/2014 Title: Shrinkage methods and functional mixed models for the analysis of large data

Audience: Quantitative seminar/Campus-wide

Location: PMCH University of Texas Medical Branch, Galveston, TX

01/2013 Title: Statistical methods in variable selection and classification

Audience: Quantitative seminar/Campus-wide

Location: PMCH University of Texas Medical Branch, Galveston, TX

10/2011 Title: A predictive model approach to dengue fever

Audience: Quantitative seminar/Campus-wide

Location: PMCH University of Texas Medical Branch, Galveston, TX