Research

Yang, Ya-Ting (Mornica)

Chelmsford, MA *****

***********@*****.***

Objective

I have studied bio-medical science for 6 years, including liver and renal disease. I would love to do more research projects and would be interested in research and development.

Employment status

U.S. Green Card

Languages

English and Mandarin

Certification

Medical Technologist

Technician Certificate, Child Care Provider

Kawai Class 5 Piano Instructor

Education

2007-2009 M.S. Biotechnology Hungkuang University

Taichung, Taiwan

2003-2007 B.S. Medical Technology Chung Hwa University of Medical

Technology, Tainan, Taiwan

Work Experience

2016- Present Research assistant, Henry M. Goldman School of Dental Medicine,

Boston University Medical Center, MA, USA

2013- 2015 Shop assistant, Teapatea, Taiwan (not continuous)

2010- 2012 Ph.D. student, Academia Sinica, Taiwan

2009- 2010 Research assistant, Tri-Service General Hospital, Taiwan

2006- 2009 Piano Instructor, Kawai, Taiwan

Research Projects

2011- 2012 (PhD thesis)

Studied knock-out mice (AC6 for the role of type VI adenylyl cyclase (AC6) signalosome in water transport of kidney.

2010- 2011

Established a cell model with C-reactive protein for inducing renal disease and investigated the mechanism of different genes.

Studied the mechanism of metastasis by injecting different malignant cells with GFP plasmid construct into mice.

Compared different knock-out mice with genes in regulation of water reabsorption.

2009- 2010

Cross-bred different strains and knock-out/in mouse.

Created animal and cell models for several renal diseases and discovered gene and herbal therapies.

Detected the associated proteins in chronic renal disease, researched the mechanism and defined the numerous biomarkers.

2007- 2009

Researched the combination of common Chinese herbal Echinacea purpura and caffeic acid to reduce fatty liver symptoms in adult zebrafish model.

Studied the effect of phenylthiocarbamide (PTC) on gene expression levels of cytochrome p450 8B1 in a transgenic zebrafish (lfabp:EGFP) line.

Skills

1.Animal models

(1)Zebrafish-Transgenic fish (microinjection)

(2)Mouse-UUO (unilateral ureteral obstruction) model, autoimmune model

2.Mouse

(1)Cross-breeding

(2)Intraperitoneal injection

(3)Intravenous injection

(4)Oral feeding

(5)Orbital sinus sampling

(6)Cardiac puncture

(7)Tail Nick

(8)Urine collection

(9)Sacrifice

(10)Lymph node isolation

(11)Perfusion

3.Techniques

(1)Cell culture

(2)Cell transfection

(3)Flow cytometry

(4)Fluorescence activated cell sorting (FACS)

(5)IVIS

(6)Confocal microscopy

(7)Phenotyping

(8)Plasmid constructs

(9)RNA/DNA/Protein extraction

(10)Western blot

(11)SDS-PAGE

(12)DNA Sequencing

(13)Polymerase chain reaction (PCR)

(14)Agarose gel electrophoresis

(15)Quantitative real time polymerase chain reaction (qPCR)

(16)ELISA

(17)TUNNEL assay

(18)T cell proliferation

(19)Thymidine uptake assay

(20)Frozen and paraffin sections

(21)Human lymphocyte primary culture

4.Tissue staining

(1)Hematoxylin &Eosin stain

(2)PAS stain

(3)Oil red o stain

(4)ISH: In situ hybridization or Whole mount

(5)IHC: immunohistochemical staining

(6)ICC: immunocytochemistry

(7)IF: immune-fluorescence

Awards

2012 Academia Sinica Fellowship (Taiwan)

2010-2012 National Defense Medical Center Fellowship (Taiwan)

2007-2009 National Science Council Fellowship (Taiwan)

Major Publications

1.Regulation of aquaporin-2 by a calcium-inhibitable adenylyl cyclase (AC6) (first author, in preparation)

2.SMAD-7 ameliorates diabetic nephropathy in mice. (secondary author, submitted)

3.IgG Fc receptor II plays a pathogenic role in the development of IgA nephropathy. (secondary author, submitted)

Conference Reports

1.Ya-Ting Yang, Yu-Shuo Wu, Hsing-Lin Lai, Chen-Li Chien, YijuangChern. Regulation of aquaporin-2 by a calcium-inhibitable adenylyl cyclase (AC6) (2012). The 27th Joint Annual Conference of Biomedical Science, in Taipei, Taiwan. 2012/03/17-2012/03/18

2.Ya-Ting Yang, G.Y. Chen, M.H.C Chen. The relationship between the gene level and of the cytochrome p450 CYP8B1 and phenylthiocarbamide (PTC) in the transgenic zebrafish (lfabpEGFP) line (2009). Deregulation of Transcription in Cancer: Controlling Cell Fate Decisions (E2), INEC-Ireland's National Events & Conference Centre, Killarney, Co. Kerry, Ireland. 2009/06/21-2009/06/26

3.Ya-Ting Yang, G.Y. Chen, C.W. W, J.L. Wu, M.H.C Chen. Expression and regulation of the cytochrome p450 CYP8B1 in the transgenic zebrafish (lfabp:EGFP) line (2009). The 24th Joint Annual Conference of Biomedical Science, Poster 651, in Taipei, Taiwan.2009/03/21-2009/03/22.

4.Ya-Ting Yang, M.C. Chang, X.J. Huang, J.L. Wu, W.L. Liao, S.D. Lin, M.H.C Chen. To Induce the Syndrome of Fatty Liver Disease by Butter in Zebrafish (2009). The 24th Joint Annual Conference of Biomedical Science, Poster 742, in Taipei, Taiwan. 2009/03/21-2009/03/22.

5.Ya-Ting Yang, S.F. Yen, W.S. Ko, C.W. Wei, J.L. Wu, M.H.C Chen. Effects of the Phenylthiocarbamide on the expression of drug-responsive genes in larvae zebrafish (2008).The 23th Joint Annual Conference of Biomedical Science, Poster 59, in Taipei, Taiwan. 2008/03/28-2008/03/29.

Special work experience

Since I enjoy tea I decided to learn how to make the best tea by working at the first and best bubble tea shop in the world, Teapatea. I started as a cashier and every 8 hour day I would encounter hundreds of customers! I had to be quick in resolving many different problems to give them the best service possible. I had to be courteous, polite, and accommodating. This was a very challenging job but I excelled at it. Even through difficult situations, I was able to communicate well and keep the shop running smoothly. I believe that everything, including running a tea shop, has an SOP, communicating with people also has an SOP. Eventually I learned all the roles in the tea shop but the most important benefit was that I learned how to communicate with people.

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