Professional Experience Assistant

MUSHTAQ AHMAD

** ****** ******

Bloomfield, NJ **003

Home: 973-***-**** *******.********@*****.***

SUMMARY

** ***** ** ********** ** an Analytical Chemist in the field of nucleosides, nucleotides, peptides and intermediates and final products as potential drug molecules. Analyzed nucleosides, nucleotides using UV, Chromatography (liquid, ion exchange and gel filtration). Analyzed peptides using amino acid analysis, electrophoresis, tryptic mapping. Strong background in NMR, UV and LC/MS instruments and flash chromatography. Experience in synthesis of nucleosides, nucleotides, peptides and investigational drug molecules.

PROFESSIONAL EXPERIENCE

HOFFMANN-ROCHE, Nutley, NJ 1970 – 2010

Associate Principal Scientist, Discovery Chemistry Department (1994-2011)

Analyzed organic compounds using TLC, HPLC, UV, IR, NMR and LC/MS to be sent for clinical evaluation.

Synthesized intermediates and final products in grams quantity to be evaluated as clinical candidate.

Research Scientist, Peptide Research Department (1976-1993)

Analyzed peptides using amino acid analysis of Thymosin alpha- 1 and Growth Hormone Releasing Factor (1-44) and clinical release for investigational studies

Identified and synthesized the sequence of Roche hepatitis C drug (PEGASYS ) that produced more antibodies than the competitor product.

Synthesis of peptides using solution and solid phase methodology from milligrams to multigrams scale.

Assistant Chemist

Analyzed oligonucleotides using ion exchange chromatography, Gel filtration, UV and HPLC.

Synthesized protected nucleotides and oligonucleotides for the mini gene project.

Prepared nucleosides and analogs for evaluation as antiviral and antitumor agent.

EDUCATION

M.S. Organic Chemistry, Punjab University,Lahore,Pakistan

One year Graduate Education, Organic Chemistry, New York University, New York, NY

PUBLICATIONS AND POSTERS

12 Publications and 10 Posters (available on request)

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