Nicholas J. Costello, MLS (ASCP)CM
Address: **** ****** ***** ***** #****, San Marcos, Texas 78666
Phone: 512-***-****
Email: *********@*****.***
Qualifications Profile
Experienced laboratory professional with leadership qualities and proven technical ability
Extensive training with complex medical diagnostic equipment in highly regulated work environments
Problem solver, with excellent ability to multitask and effectively communicate complex scenarios
In-depth understanding of FDA, OSHA, CAP and CLIA guidelines, including cGMP
Professional Experience
Grifols - San Marcos, TX
Testing Technologist September 2013 – Present
Ensure the health of donors and the safety of donor plasma by performing high–volume serologic testing
Utilize the optimal processes, communication methods, and documentation practices needed to meet FDA regulations and exceed
compliance in a worldwide market
Instrumentation: Ortho Summit System, Abbott Prism, Helena SPIFE systems, Grifols Triturus
Laboratory information system: Aurora AccLaIM (Stratec)
Austin Regional Clinic - Austin, TX
Medical Technologist III (prn) August 2012 – October 2015
Exemplified expertise in hematology, clinical chemistry, coagulation, and urinalysis in performing high-volume testing in an
organized and timely manner
Delivered accurate test results within established turnaround times above 90%
Instrumentation: Siemens Vista 1500 & Immulite 2000, Beckman LH 750, ACL Elite Pro
Laboratory information system: Orchard Harvest LIS
St. David's South Austin Medical Center - Austin, TX
Shift Supervisor April 2013 – September 2013
Planned and delegated nightly workflow to achieve above 95% productivity
Coordinated a team of technologists and phlebotomists to guarantee all duties are completed with timeliness and prioritized
appropriately
Instrumentation: Siemens Vista 1500, Haemonetics TEG 5000, Beckman Coulter LH 750 & Iris iChem Velocity
Laboratory information system: Medical Information Technology (MEDITECH)
Seton Family of Hospitals - Austin, TX
Medical Technologist II September 2008 – April 2013
Demonstrated proficiency in all areas of a complete medical laboratory including blood bank
Assisted multiple acute care hospitals by exhibiting capacity to self-start, adapt, and quickly learn numerous complex instruments
Reduced average turnaround time of troponin levels by 37% through streamlining the processing, testing, and reporting of cardiac
enzymes at Seton Williamson Hospital
Served as laboratory safety officer and Environment of Care committee member at Seton Northwest Hospital
Instrumentation: Beckman Coulter Unicel DxC 600i Synchron & Access2, Sysmex XT-1800i, Stago and ACL coagulation instruments
Laboratory information systems: Sunquest, Misys, Mediware Transfusion Software (HCLL)
The University of Texas at Austin–College of Pharmacy - Austin, TX
Research Assistant/Undergraduate Research September 2003 – January 2006
Explored the catalytic mechanism of dimethylargininase (DDAH); a significant enzyme in blood pressure regulation, cell signaling, and
progression of vascular disease
Engineered variant DDAH enzymes through site-specific mutagenesis of active site residues
Performed kinetics testing of variant DDAH enzymes with different substrates
Developed a new assay for trapping intermediate structures formed during DDAH catalysis, which supported our hypothesis of a
covalent interaction with substrate
Education and Credentials
Bachelor of Arts in Biology: December 2004
The University of Texas at Austin - Austin, TX
Medical Laboratory Scientist– American Society for Clinical Pathology: September 2008
Austin State Hospital Program in Medical Laboratory Science - Austin, TX
Awards and Honors
UT College of Natural Sciences Honors Day Award: September 2004
University Cooperative Society Undergraduate Research Fellow: September 2004
Phi Theta Kappa Honor Society: May 2000 – September 2001
Dean’s list: Spring 2000, Fall 2000, Spring 2001
Publication
Stone, E.; Costello, N.; Fast, W. (2005). Characterization of a transient covalent adduct formed during DDAH catalysis. Biochemistry,
44(18), 7069-7078.
Technical acumen
Clinical Chemistry
ELISA, PCR, TMA, ISE, spectrophotometry, electrophoresis (DNA, serum protein), chromatography (HPLC, TLC, affinity), site-specific
mutagenesis, DNA/ RNA manipulation & purification, enzyme kinetics, reagent management
Immunohematology
Collection procedures, tube testing, gel cards, antibody panels, multiple antibody crossmatch, warm auto antibodies, cold
alloantibodies, massive transfusion protocol, plasma exchange, elution, fetal bleed screen, RhIg indications, neonatal requirements,
immunocompromised indications, product storage, inventory management
Hematology
Peripheral blood smear, white cell differential, cell morphology, staining techniques, hemocytometer usage, erythrocyte sedimentation
rate, identification/differentiation of anemia, myeloproliferation, myelodysplasia, blood parasites
Coagulation
Mixing studies, platelet mapping, comprehensive whole blood hemostasis
Microbiology
Sterile processing, gram staining, culture setup
Community service
Pet Therapy; Hays Nursing and and Rehabilitation Center (San Marcos, TX): February 2016 – Present
Patient Care; Seton Northwest Hospital E.R. (Austin, TX): July 2010 – April 2013
Underprivileged Youth Assistance; Heart House (Austin, TX): May 2002 – May 2003