Medical Clinical Research
Resume:
Nicolas T. Kummer, MD-PhD
*** *** *****, *** ****, Los Angeles, CA 90095
Work Phone: 310-***-**** Mobile Phone: 310-***-**** acrlv6@r.postjobfree.com
Education
MD-PhD New York Medical College 2003 - 2011
Valhalla, NY
Bachelor of Science University of California, Santa Cruz 1994 - 1999 Santa Cruz, CA
Biochemistry and Molecular Biology
Pharmacology and Toxicology Pathway
High School Robert Louis Stevenson Boarding School 1992-1994 Pebble Beach, CA
Post-Graduate Training
Residency Radiation Oncology, University of California, Los Angeles 2012 - 2016 Los Angeles, CA
Translational Internship Mary Imogene Bassett Hospital/Columbia University 2011 - 2012 Cooperstown, New York
Licensure
California Medical License A125582 May 2012
Board Certifications
American Board of Radiology Radiation Oncology Board Eligible Pending
Citizenship
United States of America
Swiss
Professional Experience
Chief Resident UCLA Department of Radiation Oncology 2015 – 2016 Los Angeles, CA
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Research Technician III Fred Hutchinson Cancer Center 2002 – 2003 Mark Groudine, MD-PhD (PI)
Basic Science Division
Seattle, WA
Associate Research Scientist Specialty Laboratories Inc 2000 – 2002 Molecular Oncology
Santa Monica, CA
English Instructor Geneva, Switzerland 1999-2000
Scientific Research Diver Wrigley Marine Science Center 1998-1998 Catalina, CA
Clinical Lab Technician Student Health Clinic 1997-1999 University of California, Santa Cruz
Santa Cruz, CA
Academic Research Experience
Resident Research Characterization of a novel, programmable 2014-2014 Project small DNA binding molecule as a radiosensitizer UCLA Department of Radiation Oncology
Division of Molecular and Cellular Oncology
Nicholas G. Nickols, MD-PhD (PI)
Resident Research Developed a database to investigate clinically 2012-2015 Project relevant multiparametric MRI characteristics of prostate cancer
UCLA Department of Radiation Oncology
AMA Seed Grant BRAF mutations drive MMP expression and 2010-2011 tumor invasion in thyroid cancer
New York Medical College
Graduate School of Basic Medical Sciences
Graduate Student Characterization of arachidonic acid 5 lipoxygenase 2005-2009 in the molecular oncogenesis of papillary thyroid cancer New York Medical College
Graduate School of Basic Medical Sciences
Jan Geliebter, PhD (PI)
Undergraduate Bioengineering of the yeast RNA debranching enzyme 1998-1999 Senior Thesis to develop a lariat RNA isolation system University of California, Santa Cruz
Department of Molecular and Cellular Biology
Manual Ares Jr, PhD (PI)
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Grants
American Medical Association New York Medical College 2010 Seed Grant Recipient
Honors and Awards
First Place, Basic Science Poster Competition 2010 American College of Physicians, New York Regional Meeting Research Travel Award 2010
Central Society for Clinical Research, Annual Meeting Third Place, Basic Science Oral Presentation 2010
Medical Student Research Forum
New York Medical College
Research Travel Award 2008
Central Society for Clinical Research, Annual Meeting Second Place, Oral Presentation 2008
Graduate Student Research Forum
New York Medical College
Third Place, Oral Presentation 2007
Graduate Student Research Forum
New York Medical College
Dean’s Award For Outstanding Research 2004
New York Medical College
Second Place, Oral Presentation 2003
Medical Student Research Forum
New York Medical College
Research Award, Senior Thesis 1999
Student Research Symposium
University of California, Santa Cruz
Oral Presentations at National Meetings
1. Kummer NT, Mesko S, Kupelian P, Margolis D, Banerjee R, Kamrava M. Improving prostate cancer risk stratification through multiparametric MRI prostate imaging. 95th meeting of the American Radium Society; Scottsdale, AZ 2013.
2. Kummer NT, Azzi J, Iacob C, Suslina N, Komorowski Z, Schaefer S, Tiwari RK, Geliebter J, Schantz S. Correlation of Arachidonic Acid 5-lipoxygenase Expression with Tumor Invasion in Papillary Thyroid Carcinoma. 7th International Conference on Head and Neck Cancer; San Francisco, CA 2008. Nicolas T. Kummer, MD-PhD
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Presentations at International Meetings
Oral Presentation
1. Kummer NT, Yang F, Diaz-Perez S, Dervan P, Nickols NG (June, 2015). DNA Repair Interference with Sequence Specific DNA Binding Pyrrole Imidazole Polyamides; a Novel Radiation Sensitizer. Presented at the Scientific Association of Swiss Radiation Oncology Annual Meeting; Basal, Switzerland. Poster Presentation
2. Kummer NT, Margolis DJ, Mesko S, Wang J, Kupelian P, Kamrava M (June, 2015). Sub-Stratification of Intermediate Risk Group Prostate Cancer by Multi-Parametric MRI Evaluation of ADCmean Values and Maximum Tumor Diameter. Presented at the Scientific Association of Swiss Radiation Oncology Annual Meeting; Basal, Switzerland.
Poster Presentations at National Meetings
1. Kummer NT, Mesko S, Kupelian P, Kamrava M (April, 2014). Peripheral Zone Prostate Cancer Lesions on Diffusion Weighted Imaging MRI Show Different Correlations With Gleason Score, NCCN Risk and Tumor Size Than Central Lesions. Oral poster presentation. American Brachy Society Annual Meeting; San Diego, CA.
2. Kummer, NT, Nowicki, TS., Bedwell, J., Shantz, S., Tiwari, RK., Geliebter, J. (2010, April). Expression of matrix metalloproteinases are significantly increased in the papillary thyroid carcinoma cell line, BCPAP and enhance invasion by extracellular matrix degradation. Poster presentation. Annual combined meeting of CSCR and MWAFMR, Abstract #65; Chicago, IL. 3. Kummer, NT., Bedwell, J., Nowicki, TS., Schantz, S., Shin, E., Schaefer S., Tiwari, RK., Geliebter, J. (2010, April). Matrix metalloproteinase expression and secretion in papillary thyroid carcinoma. Poster presentation. American Association of Cancer Research Abstract # 529; Washington, DC. 4. Nowicki, TS., Kummer, NT., Iacob, C., Suslina, S., Moscatello, A., Shantz, S., Schaefer, S., Shin, E., Tiwari, RK., Geliebter, J. (2010, April). Inhibition of uPAR and uPA reduces invasion and degradative potential in papillary thyroid carcinoma cells. Poster presentation. Proceedings of the American Association of Cancer Research Abstract # 520; Washington, DC.
5. Kummer NT, Iacob C, Schantz S, Geliebter J. (2008, April). Upregulation of Arachidonic Acid 5- Lipoxygenase in Papillary Thyroid Carcinoma Correlates With Increased Tumor Invasion In-Vivo and Increases Extracellular Matrix Degradation and Invasion In-Vitro. Poster presentation. American Society of Clinical Investigation/American Academy of Physicians Joint Annual Meeting Abstract #191; Chicago, IL. 6. Kummer NT, Tiwari RK, Suslina N, Codrin I, Schantz S, Schaefer S, Geliebter J. (2007, April). Lipoxygenase expression in papillary thyroid carcinoma - correlation with tumor grade. Poster presentation. American Association of Cancer Research Abstract 48, #4675; San Diego, CA. 7. Kummer NT, Reyes I, Iacob C, Schaefer S, Schantz S, Geliebter J. (2006, April). 5-Lipoxygenase and 15- Lipoxygenase-2 expression in papillary thyroid carcinoma: Potential therapeutic targets and prognostic markers. Poster presentation. American Association of Cancer Research Abstract 47, #3481; Washington, DC.
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Bibliography and Publications
A. PUBLICATIONS (Peer-Reviewed)
1. Sollier E, Go DE, Che J, Gossett DR, O’Byrne S, Weaver WM, Kummer N, Rettig M, Goldman J, Nickols N, McCloskey S, Kulkarni RP, Di Carlo D. Size-selective collection of circulating tumor cells using Vortex technology. Lab Chip 2014, Jan 7; 14(1):63-77.
2. Karsy M, Arslan E, Kummer N, Mow, F. Women’s Health Initiative Findings on Glioma Incidence after Hormone Therapy in Post-Menopausal Women. PeerJ (PrePrint), Nov 13, 2013; 134v1. 3. Kummer NT, Nowicki TS, Azzi JP, Reyes I, Iacob C, Xie S, Swati I, Darzynkiewicz Z, Gotlinger KH, Suslina N, Schantz S, Tiwari RK, Geliebter J. Arachidonic 5 lipoxygenase expression in papillary thyroid carcinoma promotes invasion via MMP-9 induction. J Cell Biochem. 2012 Jun; 113(6):1998-2008. 4. Nowicki TS, Kummer NT, Iacob C, Suslina N, Schaefer S, Schantz S, Shin E, Moscatello AL, Tiwari RK, Geliebter J. Inhibition of uPAR and uPA reduces invasion in papillary thyroid carcinoma cells. Laryngoscope. 2010 Jul; 120(7): 1383-90. Cited in PubMed; PMID: 20578104. 5. Brand M, Ranish JA, Kummer NT, Hamilton J, Igarashi K, Francastel C, Chi TH, Crabtree GR, Aebersold R, Groudine M. Dynamic changes in transcription factor complexes during erythroid differentiation revealed by quantitative proteomics. Nature Structural and Molecular Biology. 2004 Jan; 11(1): 73-80. Cited in PubMed; PMID: 14718926.
B. SUBMITTED MANUSCRIPT (ACCEPTED)
1. Kang JJ, Reiter R, Kummer N, De Kernion JB, Steinberg ML, King CR. Wrong to be Right: Margin Laterality Is an Independent Predictor of Biochemical Failure after Radical Prostatectomy. American Journal of Clinical Oncology. Accepted 6/26/15.
C. SUBMITTED MANUSCRIPT (IN REVEW)
2. Kummer NT, Margolis DJ, Mesko S, Wang J, Kupelian P, Kamrava M. Sub-Stratification of Intermediate Risk Prostate Cancer by Multi-Parametric MRI into Gleason 3 and Gleason 4 Predominant Populations. Journal of Clinical Radiology.
D. PAPERS IN PREPARATION (RESEARCH COMPLETED)
1. Kummer NT, Yan F, Dervan P, Nickols N. Radiosensitization by DNA - Binding Pyrrole - Imidazole Polyamides.
E. BOOK CHAPTERS
1. Kummer NT, Gage DL. Chapter: Treatment of Tracheal Carcinomas by Radiation Oncology. In Modern Thoracic Oncology, 1st Edition. Editors: Robert B. Cameron, MD, Diana L. Gage, MD, PhD, Olga Olevsky, MD.
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Leadership
Chief Resident 2015-2016
UCLA Department of Radiation Oncology
Resident Round Table Series for Medical Students 2013-2014 UCLA Medical School
Clinical Skills Instructor 2011
New York Medical College
Valhalla, NY
Committee Member 2010-2011
American Association of Physician Scientist Policy Committee Chicago, IL
Interviewer/Student Representative 2010-2011
New York Medical College Admissions Committee
Valhalla, NY
Chapter Founder and Institutional Representative 2005-2011 American Physician Scientist Association, NYMC Chapter Valhalla, NY
Chairman, Annual Meeting Committee 2007-2008
American Physician Scientist Association
Chicago, IL
Teaching Assistant 2005-2007
Department of Microbiology and Immunology
New York Medical College
Valhalla, NY
Guest Instructor for Leadership and Development 2006 New York Medical College Science and Technology Enrichment Program For High School Students
Valhalla, NY
Residency Luncheon Program Coordinator 2005
American Physician Scientist Association Annual Meeting Chicago, IL
Founder/President 2003-2005
Public Speaking Club
New York Medical College
Chapter President 2001-2002
Toastmaster Public Speaking, Specialty Laboratories Chapter Santa Monica, CA
Vice President of Public Relations 2000-2001
Toastmaster, Specialty Laboratories Chapter
Santa Monica, CA
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Chapter Founder and President 1995-1999
Student Pugwash Science and Ethics Group
University of California, Santa Cruz
Santa Cruz, CA
HIV Test Counselor 1997-1998
University of California, Santa Cruz Health Clinic Santa Cruz, CA
Wilderness Leadership Course Co-Leader 1993
Robert Louis Stevenson High School Wilderness Leadership Program Pebble Beach, CA
President and Founder 1992-1994
SCUBA Diving Club
Robert Louis Stevenson High School
Honorary and Professional Societies
American Society for Radiation Oncology
American Medical Association
American Association of Cancer Research
American Brachytherapy Society
Scientific Association of Swiss Radiation Oncology Skills & Abilities
A. TECHNIQUES IN RADIATION ONCOLOGY
3D Conformal Radiotherapy across body sites
Eclipse (Varian Medical Systems), Tomotherapy (Accuray)
Electron therapy for cutaneous malignancies
Intensity-modulated Radiation Therapy
Eclipse and RapidArc (Varian Medical Systems), Tomotherapy (Accuray),
Image-guided and adaptive radiotherapy (Varian, Accuray)
Head and neck, thoracic, gastrointestinal, prostate, gynecological, CNS, extremity, abdomen, hepatic, retroperitoneal
Image-guided Radiation Therapy
Anatomical and fiducial-based; Adaptive radiotherapy (Varian, Accuray)
ExacTrac (BrainLab Medical Systems), Cone-Beam CT (kvCT Varian, MVCBCT Accuray)
FDG-PET/CT based (Siemens Medical Systems)
Align RT IGRT and treatment gating (Deep Inspiratory Breath Hold Breast Treatment) LINAC-based Stereotactic Body Radiation Therapy/Stereotactic Radiosurgery
Novalis TX (Varian and BrainLab Medical Systems), True Beam
CNS, Prostate, lung, liver, spine, abdomen, head and neck, extremity, and oligometastases
SRS for trigeminal neuralgia; SRS/SBRT for AVM
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MRI-Guided Radiation Therapy
ViewRay for IMRT and SBRT
Treatment gating
Adaptive planning
High Dose Rate Radiation Brachy Therapy
Significant experience with interstitial brachy therapy for prostate mono therapy, and combined with IMRT
Superficial treatment of skin cancer with Leipzig applicator, and custom applicators
Experience with interstitial brachy therapy for various body sites including breast, GYN, and head and neck
Nucletron Elekta delivery system
Planning systems
Proficient with Eclipse, iPlan, MIM, EPIC, ARIA
B. CLINICAL RESEARCH SKILLS
Database compilation, management and interrogation
Proficient with various electronic medical record systems including EPIC
Descriptive and inferential statistics on using various software platforms
Grant writing, prepared and submitted numerous grants to the AMA, ASTRO, and RSNA; awarded an AMA seed grant
C. TRANSLATION RESEARCH SKILLS
Extensive experience in developing and implementing basic science research projects in molecular oncology both independently and in a group setting
Expertise in various laboratory methodologies including molecular techniques and radiobiology. Extensive experience in real time PCR, protein chemistry, molecular genetics, clonogenic assay, radiation sensitivity enhancement ratio, DNA damage assessment, immunofluorescence chemistry, and microarrays
Professional experience translating bench-to-market novel clinical assays (work experience at Specialty Laboratories as a research associate)
D. QUALITY IMPROVEMENT
Formulated and led a department QI project to incorporate neuroradiology with our stereotactic radiosurgery and neuro-radiotherapy conference; tracked impact
Currently working to integrate medical informatics and tele-networking to standardize patient care across a network of satellite facilities
E. COMPUTER SKILLS
Proficient in Microsoft Word/Excel/PowerPoint; experience with Access
Proficient in multiple statistic platforms including JMP 11, NCSS, PRISM Graph Pad, Excel
Graphic design and editing with vector based imaging platforms, Photoshop, GNU Imaging Manipulation Program
Telecommunication with Webex and Polycom
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F. PUBLIC SPEAKING
Proficient public speaker, president of Toast Masters International local chapter, founder of public speaking club in medical school, Certified Toastmasters (CTM) Award G. LANGUAGES
English - fluent spoken, fluent written
French - fluent spoken, moderate written
Extracurricular Accomplishments
PADI Scuba diving instructor
American Associating of Underwater Scientist Research Diver 3rd degree black belt and Yoshukia Karate instructor Commercials rated instrument airplane pilot with additional sailplane rating Aerobatic aviation, sportsman rating
Eagle Scout, Boy Scouts of America
Outdoorsman, camping, backpacking, hiking, fly-fishing, skiing, surfing, boating, sailing
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