Jun Ding

*** ***** ********* **, *** *, Louisville, KY 40217

740-***-****; acr56c@r.postjobfree.com

Education

University of Maryland, Baltimore County (UMBC), Baltimore, MD

Ph.D., Mechanical Engineering, 12/2015 (expected), GPA 3.86/4.0

Research Area: Research and development of blood pump and self-expanding cannula; shear-induced hemolysis and platelet dysfunction relevant to artificial organs.

Ohio University, Athens, OH

M.S. Mechanical Engineering, 03/2011, GPA: 3.78/4.0

Research Area: Robotics and mechatronics

Sichuan University, China

B.E. Industrial Design, 06/2008

Skills

Software: Solidworks/Solidworks Simulation, Auto CAD, Matlab, Mathmatica, Tecplot, Microsoft Office, and C

Laboratory: Kinematics, dynamics, automated control, image processing, particle image velocimetry.

Research and Design Experience

Cardiovascular Innovation Institute, University of Louisville, Louisville, KY

Research Student, Department of Cardiovascular and Thoracic Surgery 11/2014-present

Animal Studies for Ventricular Assist Devices (VADs) 06/2012-present

Collected feedbacks about surgical tools associated with VAD implantation from surgeons and communicated with companies about optimization of the design of those tools for the convenience of implantation.

Provided technical support for acute and chronic studies of China Heart VAD including pre-surgery device testing, device operation and troubleshooting during surgery and post-surgery animal care.

Shear-Affected Platelet Adhesion on Immobilized Proteins 11/2014-present

Investigate the effect of shearing condition existing in artificial organs to platelet adhesion on immobilized proteins and relation between the platelet adhesion and bleeding and thrombosis potential of VAD patients.

Quantify fluorescent images of platelet adhesion by self-written image processing codes in Matlab and derive platelet adhesion model based on experimental data.

Derive platelet adhesion model based on experimental data.

Explore the relation between doses of antiplatelet drugs and platelet adhesion on the immobilized proteins.

University of Maryland, School of Medicine, Baltimore, MD

Research Student, Department of Surgery 06/2012-10/2014

Quantification of Shear-Induced Platelet Activation: High Shear Stresses for Short Exposure Time 08/2013-08/2014

Evaluated platelet activation by four platelet activation markers using flow cytometry or ELISA under high shear stress and short exposure time and obtained coefficients of power law model of platelet activation based on surface P-selectin used for prediction of platelet activation of blood contacting medical devices by computational fluid dynamics (CFD) simulation.

Research and Development of a Novel Blood Pump for 30 Day Oxygenator 02/2014-04/2014

Designed a novel blood pump for a low cost 30 day oxygenator used in extracorporeal membrane oxygenation (ECMO) using magnetic couplings from concept and built 3D model in Solidworks.

Manufactured the prototype, tested it in experiment, and optimized the design.

Repeated the cycle until the pump achieved our goal.

Research and Development of Self-Expanding Cannula 06/2012-08/2013

Designed the fixture for heat treatment for shape memory Nitinol alloy in Solidworks and implemented heat treatment to adjust the transformation temperature of the alloy.

Designed and tested the self-expanding cannula with Nitinol alloy to achieve minimal invasive intervention for ECMO and left ventricular assist device support and submitted an international patent application.

Digital Particle Image Velocimetry (DPIV) Studies on the Thoratec HeartMate III Left Ventricular Assist System (LVAS) 04/2013-06/2013

Obtained the flow fields and pressure head of Thoratec HeartMate III LVAS in different operating conditions of constant speed mode and artificial pulse mode by DPIV and submitted the study report to Thoratec for their pre-clinical report for FDA.

Ohio University, Athens, OH

Research Assistant, Department of Mechanical Engineering 09/2008-03/2011

Mechanism Design, Kinematics and Dynamics Analysis of a 7-Degree-Of-Freedom (DOF) Cable-Driven Humanoid Robot Arm 09/2008-03/2011

Designed a 3D cable-driven robotic arm with 7 DOF in Auto CAD, implemented kinematics and dynamics analysis in MATLAB and proved energy efficiency of cable-driven robotic arm.

Automated Control Cart Project 04/2009-06/2009

Designed and built hardware of a robotic cart and wrote program using C language for automated control, detecting targets and finishing missions.

Patent

Wu, Z. J., Griffith, B. P, Ding, J. (2014). Self-Expanding Cannula. International Patent Application No. PCT/US2014/046978, Patent Pending.

Publications

Chen, Z., Mondal, N. K., Ding, J., Koenig, S. C., Slaughter, M. S., Griffith, B. P., & Wu, Z. J. (2015). Activation and shedding of platelet glycoprotein IIb/IIIa under non-physiological shear stress. Molecular and Cellular Biochemistry, 1-9.

Ding, J., Chen, Z., Niu, S., Zhang, J., Mondal, N. K., Griffith, B. P., & Wu, Z. J. (2015). Quantification of Shear Induced Platelet Activation: High Shear Stresses for Short Exposure Time. Artificial organs.

Chen, Z., Mondal, N. K., Ding, J., Gao, J., Griffith, B. P., & Wu, Z. J. (2015). Shear-induced platelet receptor shedding by non-physiological high shear stress with short exposure time: glycoprotein Ibα and glycoprotein VI. Thrombosis research, 135(4), 692-698.

Ding, J., Niu, S., Chen, Z., Zhang, T., Griffith, B. P., Wu, Z. J. (2015). Shear-Induced Hemolysis: Species Differences. Artificial Organs.

Chen, Z., Zhan, F., Ding, J., Zhang, X., & Deng, X. (2014). A new stent with streamlined cross-section can suppress monocyte cell adhesion in the flow disturbance zones of the endovascular stent. Computer methods in biomechanics and biomedical engineering, 1-7.

Zhang, J., Chen, X., Ding, J., Fraser, K. H., Taskin, M. E., Griffith, B. P., & Wu, Z. J. (2013). Computational Study of the Blood Flow in Three Types of 3D Hollow Fiber Membrane Bundles. Journal of biomechanical engineering, 135(12), 121009.

Ding, J., & Williams, R. L. (2011). 7-DOF Cable-Driven Humanoid Robotic Arm. ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference (pp. 1317-1326). American Society of Mechanical Engineers.

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