Research Associate

Quinn Liu

Quinn (Qin) Liu, Ph. D.

**** *** ***, *******, ** 98121 Email: aconlh@r.postjobfree.com Mobile:631-***-****

Biochemist with 8 years of experience in protein function research.

Fast learner, creative problem solver, effective communicator with a

multidisciplinary background.

EXPERIENCE

Brookhaven National Laboratory, Upton, NY 2011-2014

Postdoctoral research associate, Department of Biosciences

Explored subunit interaction of 9 stearyol-acyl carrier protein desaturase

Developed a strategy to produce heterodimers of desaturase protein

•

Demonstrated a half-of-the-sites reactivity mechanism of a desaturase

•

protein

Identified the key amino acids disrupting the dimeric organization

•

Investigated the enzyme stabilities of desaturases

•

University of Alberta, Edmonton, Canada

Graduate research, Department of AFNS 2005-

2011

Investigated the function/structure relationship of ER membrane protein acyl-

CoA:diacylglycerol acyltransferase 2 (DGAT2).

Probed the functional and structural role of signature residues and

•

motifs in ER membrane protein DGAT2, using mutagenesis in combination with

chemical modification.

Characterized that the topological orientation of DGAT2 orhtologues is

•

not universally conserved across different species.

Identified several residues/motifs essential for DGAT2 activities.

•

Central South University, Changsha, China

Graduate research, Department of Chemistry 2002-

2005

Established a novel route to extract and partially purify polysaccharides

•

from Solanum nigrum.

Optimized the microwave-assisted extraction process of steroidal

•

alkaloids from Solanum nigrum.

TECHNICAL SKILLS

Protein biochemistry: gel electrophoresis, immunoblotting, differential scanning

fluorimetry, protein expression and coexpression, protein purification, protein labeling,

enzyme bioconjugation, UV-Vis spectroscopy, FPLC, HPLC, FRET, circular dichroism,

SAXS, radioactive assay

Lipid chemistry: Lipid Extraction and Separation, TLC, column chromatography, GC-

MS, fatty acyl-CoA and fatty acyl-ACP synthesis and purification.

1

Quinn Liu

Molecular and cell biology: PCR, DNA tailing, rapid amplification of cDNA ends,

cloning, mutagenesis, cell culture, high-throughput mutation detection, confocal

microscopy

Computer: GenBank searching, multiple sequence alignment, tree building, membrane

topology prediction and modeling, use of ExPAsy tools, familiar with software including

Vector NTI, Geneious, Clonemanager, PyMOL, Sigmaplot, Origin, ISIS/draw, Coreldraw,

Adobe Photoshop, Endnote

SIGNIFICANT HONORS AND AWARDS (13 in total)

Travel Grant for Gordon Research Conference/Seminar 2013

•

Honored Student Award, American Oil Chemist’s Society 2010

•

Second place winner of the Biotechnology Student Excellence Award,

•

American Oil Chemist’s Society 2010

Queen Elizabeth II Graduate Scholarship, University of Alberta 2009

•

•

PUBLICATIONS AND PRESENTATIONS

9 publications in peer reviewed journals (the highest impact factor is over 10 and the

citation counts are more than 90), one book chapter, two gene submissions, one U.S.

patents, and 9 presentations at international conferences.

EDUCATION

University of Alberta, Edmonton, Canada

2011

Ph. D. in biotechnology,

Central South University, Changsha, China 2002,

2005

M. Sc. and B.E. in analytical chemistry,

PROFESSIONAL ACTIVITES

Reviewer of PLOS one

Judge of WAC science fair

Mentor of the 2013 DOE internship program

member of the Protein Society, American Oil Chemists’ Society and National

Postdoctoral Association

SIGNIFICANT VOLUNTEER WORK

• Elected as lab-wide liason between Postdocs and National Laboratory Director

REFERENCES

• Available upon request.

2

Contact this candidate